ABC Transporters in Human Diseases |
Autore | Falguières Thomas |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (494 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences |
Soggetto non controllato |
ABC transporters
drug action regulatory extension regulatory insertion mechanism of action MRP1 MRP4 breast cancer proliferation migration invasion cAMP ABCG2 ABCB1 blood-brain barrier PET Alzheimer's disease beta-amyloid tariquidar erlotinib ABCG5 ABCG8 ATP-binding cassette transporter cholesterol polar relay sitosterolemia 5' untranslated region cis-acting elements ABCA subfamily bioinformatics ABC transporter therapy response disease-free survival next-generation sequencing competitive allele-specific PCR P-glycoprotein amyloid-beta neuron SK-N-SH gene therapy AAV PFIC BSEP ABCB11 bile salts intrahepatic cholestasis chaperones PFIC2 BRIC ATP-binding cassette transporter A1 (ABCA1) cholesterol homeostasis reverse cholesterol transport HDL-C dyslipidemia type 2 diabetes microparticles ABCG2 genotype clinico-genetic analysis ethnic specificity genetic variations precision medicine rare variant Roma serum uric acid SUA-lowering therapy urate transporter bile secretion ABCB4 ABCC2 ABCG5/G8 molecular partners phytosterol xenosterol atherosclerosis gall stone ABC transporter ABC (ATP-binding cassette) transporters multidrug resistance transport trafficking urate mutations polymorphisms ABCC6 TNAP NT5E Pseudoxanthoma elasticum (PXE) cancer membrane protein functional divergence calcification pseudoxanthoma elasticum generalized arterial calcification of infancy pyrophosphate therapies ABCA7 phagocytosis Aβ peptides yeast multidrug transporter anticancer antifungal resistance mechanism peroxisome adrenoleukodystrophy fatty acids gout early-onset gout hyperuricemia uric acid BCRP single nucleotide polymorphism SNP homology modeling substrate-binding site cellular ATP efflux mutagenesis intracellular traffic MDR3 phosphatidylcholine RAB GTPase taxol drug transport |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910674029103321 |
Falguières Thomas | ||
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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The Origin and Early Evolution of Life : Prebiotic Systems Chemistry Perspective |
Autore | Fiore Michele |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (320 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences |
Soggetto non controllato |
origin of life
peptidyl-transferase center pseudo-symmetry proto-ribosome SymR emergence of biological systems RNA ligation dimerization standard genetic codes codon assignment tRNA aminoacyl-tRNA synthetase classes thiophene acetylene transition metal sulfides hydrothermal conditions early metabolism origin-of-life prebiotic chemistry protein-monosaccharide recognition protein-monosaccharide interactions FRET analysis glycocodon theory glucose oxidase Mars prebiotic chemical evolution early Earth astrobiology CHNOPS transition elements sample return exoplanets complex organic molecules astrochemistry interstellar medium molecular ices solid state protoplanetary disks star forming regions comets vesicles division urea-urease enzymatic reaction bending modulus budding ADE theory dynamic kinetic stability cognition chemical evolution systems chemistry metabolism network expansion simulation temperature thermodynamics protocell compartment solid interface lipid polymerization cyclic nucleotides autocatalytic set osmotic pressure cell division lipid membrane bistable reaction system template-directed RNA synthesis origin of genetic code time order of canonical amino acids proto-metabolism chirogenesis quartz amino acids radiation damage GC×GC-TOFMS origins of life prebiotic membranes protoamphiphiles metal ions hot springs N-acyl amino acid analogue conditions viroids ribozyviruses primordial replicators ribozymes bilayer structure molecular dynamics aggregation process selection evolution Fenton chemistry reduced phosphorus pyrophosphate chemical complexity minerals schreibersite olivine serpentinite ulexite |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Origin and Early Evolution of Life |
Record Nr. | UNINA-9910580210103321 |
Fiore Michele | ||
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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