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Genetics and Genomics of Pulmonary Arterial Hypertension
| Genetics and Genomics of Pulmonary Arterial Hypertension |
| Autore | Southgate Laura |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (188 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Genetics (non-medical) |
| Soggetto non controllato |
pulmonary arterial hypertension
massive parallel sequencing NGS digenic inheritance and genetics BMPR2 promoter pathogenic variant heritable pulmonary arterial hypertension genetic analysis NGS gene panel BMPR2 TBX4 GDF2 EIF2AK4 genomics pediatrics lung disease endothelial cells smooth muscle cells DNA damage DNA repair expression quantitative trait locus eQTL blood genetics exome sequencing molecular genetics paediatrics bone morphogenetic protein receptor type 2 heritable familial estrogen estradiol penetrance gender PAH forward phenotyping forward genetics reverse genetics reverse phenotyping intermediate phenotypes whole-genome sequencing epigenetic inheritance genetic heterogeneity phenotypic heterogeneity pulmonary hypertension bone morphogenetic protein receptor 2 signaling repurposed drugs pharmaceuticals miRNA clinical trials |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595078603321 |
Southgate Laura
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Basis of Cardiovascular Diseases : : Implications of Natriuretic Peptides / / Speranza Rubattu, Massimo Volpe
| Molecular Basis of Cardiovascular Diseases : : Implications of Natriuretic Peptides / / Speranza Rubattu, Massimo Volpe |
| Autore | Rubattu Speranza |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (212 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
postmortem biochemistry
medulla animal models remodeling BNP PCSK9 guanylyl cyclase/natriuretic peptide receptor-A cardiorenal syndrome forensic medicine preserved ejection fraction kidney renin-angiotensin-aldosterone system atrial fibrillation vasopressor congestive heart failure atrial natriuretic peptide gene-knockout obesity heart failure angiogenesis adipose tissue vascular LDL receptor metabolic syndrome linkage analysis cardiometabolic disease cardiomyocyte cardiac dysfunction cardiac hypertrophy insulin lipid metabolism cGMP Idiopathic Pulmonary Arterial Hypertension (IPAH) Natriuretic Peptide Clearance Receptor (NPR-C) signaling gene-duplication renin–angiotensin system natriuretic peptides angiotensin receptor–neprilysin inhibitor cardiac remodelling ARNi NT-proBNP inflammation pulmonary arterial hypertension vascular homeostasis endothelial cell Atrial Natriuretic peptide natriuretic peptide vasodilator stroke genetic variants arterial hypertension fibroblast MANP hypertension guanylyl cyclase receptor A |
| ISBN |
9783039215836
3039215833 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367751403321 |
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Rubattu Speranza
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Mechanisms in Pulmonary Hypertension and Right Ventricle Dysfunction
| Molecular Mechanisms in Pulmonary Hypertension and Right Ventricle Dysfunction |
| Autore | Karmouty-Quintana Harry |
| Pubbl/distr/stampa | Frontiers Media SA, 2019 |
| Descrizione fisica | 1 online resource (170 p.) |
| Collana | Frontiers Research Topics |
| Soggetto topico |
Physiology
Science: general issues |
| Soggetto non controllato |
Bleomycin
endothelial cell Fibrosis hypoxia Inflammation Iron Mitochondria pulmonary arterial hypertension Smooth Muscle Cell vascular remodeling |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557237303321 |
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Karmouty-Quintana Harry
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| Frontiers Media SA, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Oligonucleotide, Therapy, and Applications
| Oligonucleotide, Therapy, and Applications |
| Autore | Aliño Salvador |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (123 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Amplex Red
anti-proliferative activity antisense oligonucleotide antisense oligonucleotides antisensense oligonucleotide aptamer aptasensor covalent dimer construct DNA methylation DNAzyme dopamine neurotransmission double mutant A30P*A53T* exon skipping fibrillin-1 Foxp3 G-quadruplexes histone code influenza light-induced activity Marfan syndrome microRNA motor deficits nanoparticles noncoding RNA Parkinson's disease primary cell culture of human glioma pulmonary arterial hypertension quantum dots (QDs) regulatory T cells ROS SERS splice-switching Sporothrix schenckii transgenic mouse model vaccine immunogenicity virus detection α-synuclein |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557615903321 |
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Aliño Salvador
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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PPARs as Key Mediators of Metabolic and Inflammatory Regulation
| PPARs as Key Mediators of Metabolic and Inflammatory Regulation |
| Autore | Vázquez-Carrera Manuel |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (456 p.) |
| Soggetto topico |
Biochemistry
Biology, life sciences Research and information: general |
| Soggetto non controllato |
adipose tissue
AMPK amygdala atopic dermatitis bezafibrate brain browning cancer common carotid artery occlusion coregulator corticotropin releasing hormone coumarin crystal structure cytomegalovirus dairy animals depression diabetes DNA methylation docking doping control dual/pan agonist electroretinography ELISA energy homeostasis exercise fatty acid oxidation fatty acids fenofibrate fenofibric acid fibroblast growth factor 21 fluorescent ligand GDF15 gene transcription glucose GSK3787 GW0742 hepatic damage hepatic sex-biased gene expression histone modification HIV immunity immunohistochemistry infection inflammation insulin resistance kidney fibrosis ligand lipid droplets lipid metabolism lipidomics lipopolysaccharide (LPS) liver damage lung M. leprae M. tuberculosis metabolic alterations metabolic reprograming metabolic syndrome microglia micronutrients miRNA molecular docking mycobacteria n/a neural stem cells neurogenesis neuroinflammation neuropathology nitric oxide synthase non-alcoholic fatty liver disease (NAFLD) non-alcoholic steatohepatitis (NASH) nonalcoholic fatty liver disease (NAFLD) norepinephrine nuclear factors nuclear receptor nuclear receptors nucleus accumbens nutrigenomics obesity oleoylethanolamide P2Y2 receptor palmitoylethanolamide pattern-recognition receptors pemafibrate peroxisome peroxisome proliferator-activated receptor peroxisome proliferator-activated receptor alpha peroxisome proliferator-activated receptor gamma (PPARγ) peroxisome proliferator-activated receptors (PPAR) peroxisome-proliferator-activated receptor phagocytosis pharmacological targets PPAR PPAR gamma PPARg PPARs PPARα PPARα knockout PPARβ/δ PPARγ PPARγ ligand PPRE proliferation psoriasis pulmonary arterial hypertension pulmonary artery quercetin real-time PCR regulatory T cells resveratrol retinal ischemia screening sex dimorphism signaling pathway skeletal muscle subgenual prefrontal cortex substrate metabolism TGFβ toll-like receptor 4 type 2 diabetes mellitus vascular injury X-ray crystallography Zika β-oxidation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576873703321 |
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Vázquez-Carrera Manuel
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Rheumatic Diseases: Pathophysiology, Targeted Therapy, Focus on Vascular and Pulmonary Manifestations
| Rheumatic Diseases: Pathophysiology, Targeted Therapy, Focus on Vascular and Pulmonary Manifestations |
| Autore | Ruaro Barbara |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (178 p.) |
| Soggetto topico |
Medicine and Nursing
Pharmacology |
| Soggetto non controllato |
3D-echocardiography
airway disease antifibrotic agents cardiopulmonary exercise testing connective tissue diseases COVID-19 CX3CL1/fractalkine CX3CR1 diffuse alveolar hemorrhage efficacy fibromyalgia gastrointestinal symptoms heart failure high-resolution computed tomography infection inflammatory response interstitial lung disease interstitial lung diseases IPF M1 macrophage M2 macrophage microvascular involvement nailfold capillaroscopy osteopontin outcome pharmacological interactions pleurisy PMR polymyalgia rheumatica probiotic progressive fibrosing ILD pulmonary arterial hypertension pulmonary function tests pulmonary involvement rheumatic rheumatoid arthritis scleroderma shrinking lung syndrome SKG mice systemic lupus erythematosus systemic sclerosis t-vns targeted therapy tolerability UIP vagus nerve stimulation ventricular function ventricular-arterial coupling VSL#3® |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Rheumatic Diseases |
| Record Nr. | UNINA-9910566486303321 |
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Ruaro Barbara
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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