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Celebrating 120 Years of Butantan Institute Contributions for Toxinology
| Celebrating 120 Years of Butantan Institute Contributions for Toxinology |
| Autore | Moura-Da-Silva Ana Maria |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (408 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
mass spectrometry
proteome snake venom Bothrops jararaca breast cancer HF3 human plasma proteolysis snake venom metalloproteinase Bothrops atrox blister local damage DAMPs antivenom snakebite Bothrops metalloproteases inflammation microcirculation adhesion molecules leukocyte-endothelium interactions individual variability venom heterogeneity STEC Stx2 antibody fragment monoclonal antibody neurodegenerative disease neurodegeneration IL-17 glial cells crotoxin epithelial-mesenchymal transition spheroid model tumor stroma Lonomia envenoming innovation Tityus serrulatus venom components hypotensins NEP inhibition cytokines toxins venoms skin secretion drug discovery scorpion accidents lactation maternal care seizure threshold leech Haementeria vizottoi cysteine proteases inhibitor recombinant cystatin cathepsin L Cryptops iheringi centipede venom toxin transcriptome recombinant protein venomics chilopoda oral tolerance ELISA Bothrops phospholipases A2 lipid mediators signaling pathways fish venoms cytolysins multifunctionality pore formation Bitis arietans venom (BaV) Kn-Ba cytokines and chemokines PGE2 THP-1 macrophages analgesic peptide protein kinase C hyperalgesia cell-signaling Hyalomma dromedarii salivary glands serpin anticoagulants thrombin inhibitor β-defensins snakes antimicrobial activity bioisosterism peptides Thalassophryne nattectin reverse-phase HPLC MALDI-ToF hemagglutinating activity antibacterial activity toxinology animal toxins |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674030303321 |
Moura-Da-Silva Ana Maria
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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In Silico Strategies for Prospective Drug Repositionings
| In Silico Strategies for Prospective Drug Repositionings |
| Autore | Udrescu Lucreția |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (288 p.) |
| Soggetto topico |
Medicine
Pharmaceutical industries |
| Soggetto non controllato |
COVID-19
drug repurposing topological data analysis persistent Betti function SARS-CoV-2 network-based pharmacology combination therapy nucleoside GS-441524 fluoxetine synergy antidepressant natural compounds QSAR molecular docking drug repositioning UK Biobank vaccine LC-2/ad cell line drug discovery docking MM-GBSA calculation molecular dynamics cytotoxicity assay GWAS multiple sclerosis oxidative stress repurposing ADME-Tox bioinformatics complex network analysis modularity clustering ATC code hidradenitis suppurativa acne inversa transcriptome proteome comorbid disorder biomarker signaling pathway druggable gene drug-repositioning MEK inhibitor MM/GBSA Glide docking MD simulation MM/PBSA single-cell RNA sequencing pulmonary fibrosis biological networks p38α MAPK allosteric inhibitors in silico screening computer-aided drug discovery network analysis psychiatric disorders medications psychiatry mental disorders toxoplasmosis Toxoplasma gondii in vitro screening drug targets drug-disease interaction target-disease interaction DPP4 inhibitors lipid rafts |
| ISBN | 3-0365-6133-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639987703321 |
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Udrescu Lucreția
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Integrative Multi-Omics in Biomedical Research
| Integrative Multi-Omics in Biomedical Research |
| Autore | Gerner Christopher |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (178 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
target identification
target validation label-free method for drugs anti-angiogenesis mechanism of action receptor tyrosine kinases curcumin natural products lipid lipidomics cardiac metaplasia Barrett's esophagus esophageal adenocarcinoma microbiota DNA sensing IFI16 cGAS innate immunity protein interactions virus-host interactions post-translational modifications mass spectrometry proteomics transcriptomics multi-omics multi-omics analysis study design bioinformatics machine learning analysis flow metabolomics planned myocardial infarction (PMI) myocardial infarction (MI) exercise heart cheminformatics batch variations eicosanoids fetal calf serum peroxisomes host-pathogen interactions secretome macrophages acute myeloid leukemia HL-60 cell line ATRA induced differentiation transcriptome proteome transcription factors key molecules regulatory pathway modelling SRM endometriosis inflammation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557769003321 |
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Gerner Christopher
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Kinetoplastid Genomics and Beyond
| Kinetoplastid Genomics and Beyond |
| Autore | Requena Jose M |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (251 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
trypanosomatids
yeasts trypanosomatids genome cell cycle phases S-phase duration DNA replication replication origins neglected tropical diseases Leishmania Trypanosoma cruzi Trypanosoma brucei drug discovery in vitro models in vivo models genomics drug resistance Leishmania infantum proteome post-translational modifications (PTMs) proteogenomics mass spectrometry Retrotransposon Hot Spot (RHS) multigene family chromosome distribution recombination gene mosaic structure evolution nuclear protein Leishmania braziliensis reverse genetics CRISPR–Cas9 gene targeting phenotyping heat shock proteins Trypanosoma cruzi strain sequencing methods genome plasticity gene expression trans-sialidases mucins SENP Ulp2 SUMO CRISPR protease genome repeats 3′UTR multigenic family Leishmania donovani whole-genome sequencing (WGS) transcriptome artemisinin drug resistance Leishmania viruses phylogeny coevolution endosymbiont protozoan viruses transcriptome assembly transcriptional regulation ontology network co-expression network taxonomic analysis database contamination kleptoplastidy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557679003321 |
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Requena Jose M
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Bioactive Peptides II: Structure, Function, and Therapeutic Potential
| Marine Bioactive Peptides II: Structure, Function, and Therapeutic Potential |
| Autore | Ovchinnikova Tatiana V |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (228 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Spanish mackerel (Scomberomorous niphonius)
muscle peptide antioxidant activity stability biological activity chemistry marine derived fungi peptides biotransformation laxaphycin autophagy apoptosis cyanobacteria bioactive peptides marine secondary structure proline mechanism of activity marine waste antimicrobial peptide polychaeta innate immunity BRICHOS domain recombinant peptide β-hairpin structure nuclear magnetic resonance (NMR) arenicin complement system complement regulation jellyfish Rhopilema esculentum Sanderia malayensis proteome venom toxin hydrolysate fish protein ageing physical function dietary assessment seafood intake healthy ageing marine organism anticancer medicine small peptide liner peptide cyclic peptide marine peptide dolastatin 10 antitumor lead exploration |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Marine Bioactive Peptides II |
| Record Nr. | UNINA-9910557353303321 |
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Ovchinnikova Tatiana V
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Plant Protein and Proteome Altlas--Integrated Omics Analyses of Plants under Abiotic Stresses
| Plant Protein and Proteome Altlas--Integrated Omics Analyses of Plants under Abiotic Stresses |
| Autore | Li Ling |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (558 p.) |
| Soggetto non controllato |
phosphoproteomics
GLU1 somatic embryogenesis CHA-SQ-1 nitrogen fertilizer chilling stress differentially abundant proteins ATP synthase photosynthetic parameters photosynthesis constitutive splicing phosphorylation Jatropha curcas plants under stress postharvest freshness Alternanthera philoxeroides rubber latex Millettia pinnata molecular and biochemical basis filling kernel drought stress comparative proteomic analysis domain micro-exons phylogeny phos-tagTM E. angustifolia root cell elongation ABA pollen abortion lncRNA transcriptome radish redox homeostasis Nelumbo nucifera sugar beet shotgun proteomics proteomes high-temperature stress post-genomics era model plant salt tolerance miRNA wheat physiological response stress visual proteome map transcriptional dynamics leaf maize Dunaliella salina phosphatidylinositol S-adenosylmethionine decarboxylase Gossypium hirsutum flavonoid biosynthesis phosphatase wood vinegar heat shock proteins silicate limitation purine metabolism natural rubber biosynthesis ancient genes cotton rubber grass abiotic stress heat stress maturation low-temperature stress molecular basis transcriptome sequencing ROS scavenging widely targeted metabolomics transdifferentiation seed development alternative splicing cultivars inositol salt stress chlorophyll fluorescence parameters proteome carbon fixation AGPase transcript-metabolite network molecular mechanisms Triticum aestivum L. Zea mays L. ROS label-free quantification woody oilseed plants heat-sensitive spinach variety MIPS quantitative proteomics regulated mechanism two-dimensional gel electrophoresis potassium glutathione Salinity stress integrated omics diatom ATP synthase CF1 alpha subunit (chloroplast) root proteome atlas brittle-2 mass spectrometry genomics Taraxacum kok-saghyz cytomorphology proteomics arbuscular mycorrhizal fungi signaling pathway proteomic loss-of-function mutant rice seedling wucai leaf sheath root and shoot antioxidant enzyme exon-intron structure diversity isobaric tags for relative and absolute quantitation regulation and metabolism concerted network drought heat response VIGS iTRAQ nitrogen use efficiency (NUE) stem |
| ISBN | 3-03921-961-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404080203321 |
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Li Ling
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Plant Proteomic Research 2.0
| Plant Proteomic Research 2.0 |
| Autore | Komatsu Setsuko |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (594 p.) |
| Soggetto non controllato |
14-3-3 proteins
targeted two-dimensional electrophoresis somatic embryogenesis nitrogen metabolism subtilase Sporisorium scitamineum non-orthodox seed antioxidant activity sweet potato plants infected by SPFMV photosynthesis B. acuminata petals chlorophyll deficiency seed proteomics imbibition pollination Sarpo Mira qRT-PCR holm oak tuber phosphoproteome isobaric tags for relative and absolute quantitation (iTRAQ) Quercus ilex nucleotide pyrophosphatase/phosphodiesterase lettuce ?-subunit protein phosphatase germination drought stress pyruvate biosynthesis weakening of carbon metabolism differential proteins heterotrimeric G protein organ LC-MS-based proteomics potato proteomics smut gel-free/label-free proteomics ? subunit shotgun proteomics 2D chloroplast proteome functional annotation Phalaenopsis Clematis terniflora DC wheat Dn1-1 carbon metabolism physiological responses Zea mays phenylpropanoid biosynthesis ISR mass spectrometric analysis patatin leaf pea (Pisum sativum L.) maize ergosterol Camellia sinensis seed storage proteins silver nanoparticles elevated CO2 metacaspase SPV2 and SPVG SnRK1 MALDI-TOF/TOF (phospho)-proteomics leaf spot rice isogenic line wheat leaf rust pathway analysis phosphoproteome sugarcane senescence Oryza sativa L. Arabidopsis thaliana heat stress gene ontology innate immunity Pseudomonas syringae bolting chlorophylls shoot Simmondsia chinensis RT-qPCR stresses responses Solanum tuberosum seeds GC-TOF-MS sucrose proteome Puccinia recondita cultivar Zea mays L. secondary metabolism ROS Ricinus communis L. after-ripening cadmium Stagonospora nodorum virus induced gene silencing quantitative proteomics sweet potato plants non-infected by SPFMV affinity chromatography population variability GS3 fungal perception ammonium transcriptome profiling mass spectrometry analysis papain-like cysteine protease (PLCP) cold stress nitrate late blight disease early and late disease stages seed imbibition lesion mimic mutant protease proteome map seed dormancy petal 2-DE proteomics 2D DIGE root Phytophthora infestans differentially abundant proteins (DAPs) polyphenol oxidase degradome flavonoid 14-3-3 caspase-like proteomics RGG4 co-infection plasma membrane chlorotic mutation Medicago sativa RGG3 glycolysis barley 2-DE protein phosphorylation western blotting N utilization efficiency rice plant pathogenesis responses high temperature data-independent acquisition pattern recognition receptors vegetative storage proteins leaf cell wall proteome plant-derived smoke iTRAQ starch proteome profiling Morus |
| ISBN | 3-03921-063-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346666103321 |
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Komatsu Setsuko
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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