Info
- Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.
Anticancer Inhibitors
| Anticancer Inhibitors |
| Autore | Fantacuzzi Marialuigia |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (216 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
breast cancer
tamoxifen LY294002 synergism apoptosis cell cycle tea (Camellia sinensis) flowers BTFS A2780/CP70 ovarian cancer cells S phase cell cycle arrest nicotinamide phosphoribosyltransferase NAD+ biosynthesis inhibitor azacyclohexane anticancer drug drug design enthalpy effect NSCLC Cathepsin K cell proliferation cell migration cell invasion mTOR isatin-hydrazones cytotoxicity CDK2 inhibitor ATP competitive inhibitor ADME analysis receptor tyrosine kinases protein-protein interactions protein engineering directed evolution angiogenesis binding affinity agonistic activity saponins phytochemicals tea (Camellia sinensis) flower ovarian cancer autophagy ZMYND8 tumorigenesis epigenetic regulation pro-oncogenic effects tumor suppression tacrine-coumarin derivatives DNA topoisomerases I, II lung carcinoma cells A549 chemotherapy prodrug drug targeting overexpressed enzymes ADC ADEPT GDEPT LEAPT PROTAC cyclin-dependent kinase cancer resistance small molecule inhibitors PROTACs statins pancreatic cancer DNA microarray pitavastatin cerivastatin simvastatin fluvastatin atorvastatin pravastatin HMG-CoA reductase inhibitors |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595069203321 |
Fantacuzzi Marialuigia
|
||
| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Celebrating Applied Sciences Reaches 20,000 Articles Milestone : Feature Papers in Applied Biosciences and Bioengineering Section
| Celebrating Applied Sciences Reaches 20,000 Articles Milestone : Feature Papers in Applied Biosciences and Bioengineering Section |
| Autore | Cappello Francesco |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (228 p.) |
| Soggetto topico |
Technology: general issues
Biotechnology |
| Soggetto non controllato |
biothiols
blood plasma gold nanoparticles colorimetric probes chaperone system Hsp60 gastritis gastric dysplasia gastric carcinogenesis intestinal metaplasia LAMP Salmonella ISO 16140:2016 food-borne validation specificity sensitivity accuracy kit elderberry Sambucus nigra L. juice concentrate storage effect phenolic compounds berries anthocyanins' stability polymeric color ABTS•+ antioxidant capacity endothelial glycocalyx inflammatory response fluid loading surgery post-operative albumin extravasation serum HSP90 gamma-delta T cells acute lymphoblastic leukaemia halophyte sea purslane minerals antioxidant activity novel ingredient epilepsy systems biology protein-protein interactions CNS Gibbs homology drug targets anti-epileptic drugs periodontitis inflammation oils volatile heart disease risk factors asthma chronic obstructive pulmonary disease COPD epithelial-mesenchymal trophic unit muco-microbiotic layer nanovesicles exosomes outer membrane vesicles microbiota spheroid organoid van der Waals force fluoropolymers adhesion microstamp extracellular vesicles liquid biopsy biomarkers tumor progression metastasis drug delivery halloysite nanoclay regenerative medicine tissue engineering wound healing stroke yoga balance disability depression levetiracetam critically ill patients population pharmacokinetic modeling simulated dosage schemes intensive care unit |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Celebrating Applied Sciences Reaches 20,000 Articles Milestone |
| Record Nr. | UNINA-9910580215703321 |
|
Cappello Francesco
|
||
| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Disease and the Hippo Pathway: Cellular and Molecular Mechanisms
| Disease and the Hippo Pathway: Cellular and Molecular Mechanisms |
| Autore | Hansen Carsten Gram |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (226 p.) |
| Soggetto non controllato |
STRIPAK
skin cancer Lats2 transcription myofibroblast epigenetic Hippo cancer immunity TAZ Taz TAZ (transcriptional co-activator with PDZ-binding motif) adaptive immunity fibroblasts innate immunity LATS MST (mammalian STE20-like protein kinase) phosphorylation stem cells wound healing signal transduction angiogenesis LATS1/2 EMT protein-protein interactions structure biology Hippo pathway hippo pathway autoimmunity Mps one binder YAP/TAZ GPCR fibrosis MST1/2 YAP (yes-associated protein) YAP Yap protein kinase LATS (large tumor suppressor kinase) peripheral nerve sheath tumor signal cross-talk stem cell skin development STK38 tumorigenesis NDR schwannoma G protein-coupled receptor anti-cancer therapy feedback loops vascular mimicry castration resistance chromatin Hippo signalling ECM MST prostate cancer TEAD cancer zebrafish |
| ISBN | 3-03921-777-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Disease and the Hippo Pathway |
| Record Nr. | UNINA-9910367742003321 |
|
Hansen Carsten Gram
|
||
| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Malignant Mesothelioma
| Malignant Mesothelioma |
| Autore | L. Pouliquen Daniel |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (328 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
well-differentiated papillary mesothelioma
WDPM malignant mesothelioma DNA sequencing mutation mesothelioma tumor suppressor targeted therapy immunotherapy biomarkers proteomics macrophage-capping protein fatty acid-binding protein laminin subunit beta-2 selenium-binding protein 1 carcinogenesis malignant pleural mesothelioma asbestos exposure DNA methylation lymphocyte-to-monocyte ratio epigenome-wide analysis survival analysis metabolomics radiotherapy cancers inflammation infiltrating immune cells prognostic biomarker predictive biomarker immune therapy VATS extrapleural pneumonectomy pleurectomy decortication therapy response survival FDG PET-CT mesothelium oxidative stress redox-sensitive factors asbestos carbon nanotubes protein-protein interactions systems biology network analysis drug repurposing pleural mesothelioma gene expression immunogenicity sarcomatoid epithelioid first line meta-analysis systematic review MPM lurbinectedin DNA damage response histotype Hippo pathway NF2 BAP1 CDKN2A PTCH1 SETD2 MTAP liquid biopsies circulating tumor DNA plasma cancer-specific mutations genomics cancer biomarkers tumor microenvironment tumor-associated macrophages dendritic cells immunohistochemistry interaction analysis pleural effusion |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557359303321 |
|
L. Pouliquen Daniel
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Mechanisms of ER Protein Import
| Mechanisms of ER Protein Import |
| Autore | Zimmermann Richard |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (258 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
chaperones
contact sites endoplasmic reticulum ER-SURF membrane extraction mitochondria protein targeting bimolecular luminescence complementation competition split luciferase membrane proteins protein-protein interactions Sec61 complex Sec63 synthetic peptide complementation TRAP complex ER protein translocase signal peptide protein translocation nascent peptide chain membrane insertion molecular modelling molecular dynamics simulations molecular docking signal peptidase ER translocon signal recognition particle dependent protein targeting Sec61 dependent translocation co-translational translocation inhibitor high throughput screening Sec61 Sec62 folding insertion membrane protein translocon ribosome transmembrane segment lipid droplets peroxisomes PEX3 membrane protein insertion label-free quantitative mass spectrometry differential protein abundance analysis Zellweger syndrome GET protein transport SND SRP EMC positive-inside rule hydrophobicity transmembrane helix signal recognition particle nascent polypeptide-associated complex fidelity cyclotriazadisulfonamide ER quality control DNAJC3 preprotein Sec61 translocon ribosome stalling signal sequence Sec61 translocase NAC |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576886203321 |
|
Zimmermann Richard
|
||
| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Natural Language Processing: Emerging Neural Approaches and Applications
| Natural Language Processing: Emerging Neural Approaches and Applications |
| Autore | Esposito Massimo |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (544 p.) |
| Soggetto topico |
Information technology industries
Computer science |
| Soggetto non controllato |
tourism big data
text mining NLP deep learning clinical named entity recognition information extraction multitask model long short-term memory conditional random field relation extraction entity recognition long short-term memory network multi-turn chatbot dialogue context encoding WGAN-based response generation BERT word embedding text summary reinforce learning FAQ classification encoder-decoder neural network multi-level word embeddings BERT bidirectional RNN cloze test Korean dataset machine comprehension neural language model sentence completion primary healthcare chief complaint virtual medical assistant spoken natural language disease diagnosis medical specialist protein-protein interactions deep learning (DL) convolutional neural networks (CNN) bidirectional long short-term memory (bidirectional LSTM) dialogue management user simulation reward shaping conversation knowledge multi-agent reinforcement learning language modeling classification error probability error assessment logic error neural network LSTM attention mechanism programming education neural architecture search word ordering Korean syntax adversarial attack adversarial example sentiment classification dual pointer network context-to-entity attention text classification rule-based word embedding Doc2vec paraphrase identification encodings R-GCNs contextual features sentence retrieval TF−ISF BM25 partial match sequence similarity word to vector word embeddings antonymy detection polarity text normalization natural language processing deep neural networks causal encoder question classification multilingual convolutional neural networks Natural Language Processing (NLP) transfer learning open information extraction recurrent neural networks bilingual translation speech-to-text LaTeX decompilation word representation learning word2vec sememes structural information sentiment analysis zero-shot learning news analysis cross-lingual classification multilingual transformers knowledge base commonsense sememe prediction attention model ontologies fixing ontologies quick fix quality metrics online social networks rumor detection Cantonese XGA model delayed combination CNN dictionary named entity recognition deep learning NER bidirectional LSTM CRF CoNLL OntoNotes toxic comments neural networks |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Natural Language Processing |
| Record Nr. | UNINA-9910566478103321 |
|
Esposito Massimo
|
||
| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Plant Responses and Tolerance to Salt Stress: Physiological and Molecular Interventions
| Plant Responses and Tolerance to Salt Stress: Physiological and Molecular Interventions |
| Autore | Hasanuzzaman Mirza |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (364 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
CPA gene family
RsNHX1 over-expression virus-induced gene silence salt resistance radish 14-3-3 gene family Triticum aestivum L. bioinformatics analysis salt tolerance protein-protein interactions Populus simonii × P. nigra PsnNAC036 transcription factor salt stress HT tolerance ion transport osmotic homeostasis hormone mediation cell wall regulation salt adaptation proteomics microtubules tubulin phenolic metabolites lemon balm chlorophyll fluorescence medicinal plants secondary metabolites abiotic elicitors salinity betaine aldehyde dehydrogenase 1 (BADH1) domestication cultivated rice wild rice Hordeum vulgare L. RNA-seq analysis differentially expressed genes tolerance candidate genes C3-CAM intermediate common ice plant Mesembryanthemum crystallinum osmotic stress abiotic stress antioxidant defense climate change hydrogen peroxide lipid peroxidation oxidative stress phytohormones stress signaling mulberry TMT proteomics phenylpropanoid metabolism apoplast functional screening Hordeum vulgare seedling halophyte species NADPH oxidases NOX respiratory burst oxidase homolog RBOH gene expression saline adaptations C2H2 zinc finger protein heterologous expression Millettia pinnata thaumatin-like proteins (TLPs) bolTLP1 broccoli drought stress antioxidants carbohydrates carotenoids xanthophyll cycle osmoprotectants ROS-scavengers α-/γ-tocopherols quantitative trait locus (QTL) association analysis marker-assisted selection (MAS) rice (Oryza sativa L.) hydroxyindole-O-methyltransferase gene melatonin ROS ABA ion homeostasis amino acids Malus domestica calcium calcineurin B-like proteins Na+ accumulation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Plant Responses and Tolerance to Salt Stress |
| Record Nr. | UNINA-9910576886303321 |
|
Hasanuzzaman Mirza
|
||
| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Recent Trends in Computational Research on Diseases
| Recent Trends in Computational Research on Diseases |
| Autore | Altaf-Ul-Amin Md |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (130 p.) |
| Soggetto topico |
Technology: general issues
History of engineering & technology |
| Soggetto non controllato |
water temperature
bathing ECG heart rate variability quantitative analysis t-test hypertrophic cardiomyopathy data mining automated curation molecular mechanisms atrial fibrillation sudden cardiac death heart failure left ventricular outflow tract obstruction cardiac fibrosis myocardial ischemia compound-protein interaction Jamu machine learning drug discovery herbal medicine data augmentation deep learning ECG quality assessment drug-target interactions protein-protein interactions chronic diseases drug repurposing maximum flow adenosine methylation m6A RNA modification neuronal development genetic variation copy number variants disease-related traits sequential order association test blood pressure cuffless measurement longitudinal experiment plethysmograph nonlinear regression |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566465403321 |
|
Altaf-Ul-Amin Md
|
||
| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The Amazing World of IDPs in Human Diseases
| The Amazing World of IDPs in Human Diseases |
| Autore | Monti Simona Maria |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (196 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
alpha-synuclein
NMR secondary structure propensity pre-structured motifs (PreSMos) intrinsically disordered protein ubiquitin-proteasome system intrinsically disordered proteins protein misfolding molecular recognition features cancer neurodegenerative diseases protein degradation EPR spectroscopy isothermal titration calorimetry protein-ligand interaction site-directed spin labeling protein structural dynamics WASp interacting protein protein-protein interactions actin cytoskeleton remodeling SH3 domain proline-rich motif single nucleotide variants interface core and rim human disease intrinsically disordered regions linear motifs gene duplications de novo evolutionary origin circular dichroism flexibility fluorescence importin isothermal titration calorimetry (ITC) molecular docking nuclear magnetic resonance (NMR) nuclear protein 1 (NPR1) peptide Methyl-CpG-binding protein 2 (MeCP2) Rett syndrome intrinsically disordered protein (IDP) protein stability protein-DNA interaction proteostasis ubiquitin independent degradation NADH-26S proteasome |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557334303321 |
|
Monti Simona Maria
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Toxin-Antitoxin Systems in Pathogenic Bacteria
| Toxin-Antitoxin Systems in Pathogenic Bacteria |
| Autore | Alonso Juan Carlos |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (170 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
tuberculosis
toxin-antitoxin systems bacterial cell death NAD+ stress-response toxin-antitoxin system mazF type II toxin mRNA interferase X-ray crystallography cognate interactions cross-interactions molecular insulation antitoxin TA systems addiction anti-addiction type I toxin-antitoxin system small protein toxin structure Fst/Ldr family toxin-antitoxin M. tuberculosis bacteria pathogenesis protein-protein interactions cross-talk protein interface tolerance persistence cross-resistance PemI/PemK Klebsiella pneumoniae toxin activation antibacterial agents bacterial persistence Stenotrophomonas maltophilia opportunistic pathogen clinical origin environmental origin biofilm antibiotic resistance cell wall inhibition nucleotide hydrolysis uridine diphosphate-N-acetylglucosamine |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674020103321 |
|
Alonso Juan Carlos
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
