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Protein-Ligand Interactions: Target Identification and Drug Discovery
| Protein-Ligand Interactions: Target Identification and Drug Discovery |
| Autore | Altieri Fabio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (184 p.) |
| Soggetto topico |
Chemistry
Research and information: general |
| Soggetto non controllato |
ACE
acetylcholinesterase amyloid beta aggregation brassicasterol cancer cell death cell viability CoCl2 drug development drug discovery endocrine disruptor compound fatty acid conjugation FcRn-mediated recycling fluorescence spectroscopy GADD45β heat shock protein 70 Hsp70 HSV HSV-1 DNA polymerase HSV-1 TK human CDK2 human umbilical artery kinase regulation lipid signalling lipid-protein interaction lung cancer cell line membrane mitochondrial membrane potential MKK7 molecular biophysics molecular docking molecular docking simulation molecular dynamics multi-target drug multiple myeloma Mycobacterium tuberculosis NCI60 COMPARE analysis neuroprotection PGRMC1 phosphatidylinositols phytosterols piperine protein-ligand interaction reactive oxygen species (ROS) serum albumin serum half-life extension sigma ligands sigma receptors SIGMAR1 small-molecule derivatives of salicylanilide STD-NMR structure-activity relationship target identification thyroid diseases TMEM97 translocator protein (TSPO) UDP-galactopyranose mutase vascular homeostasis |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
Protein—Ligand Interactions
Protein-Ligand Interactions Protein–Ligand Interactions |
| Record Nr. | UNINA-9910557497703321 |
Altieri Fabio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Amazing World of IDPs in Human Diseases
| The Amazing World of IDPs in Human Diseases |
| Autore | Monti Simona Maria |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (196 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
actin
alpha-synuclein cancer circular dichroism cytoskeleton remodeling de novo EPR spectroscopy evolutionary origin flexibility fluorescence gene duplications human disease importin interface core and rim intrinsically disordered protein intrinsically disordered protein (IDP) intrinsically disordered proteins intrinsically disordered regions isothermal titration calorimetry isothermal titration calorimetry (ITC) linear motifs Methyl-CpG-binding protein 2 (MeCP2) molecular docking molecular recognition features n/a NADH-26S proteasome neurodegenerative diseases NMR nuclear magnetic resonance (NMR) nuclear protein 1 (NPR1) peptide pre-structured motifs (PreSMos) proline-rich motif protein degradation protein misfolding protein stability protein structural dynamics protein-DNA interaction protein-ligand interaction protein-protein interactions proteostasis Rett syndrome secondary structure propensity SH3 domain single nucleotide variants site-directed spin labeling ubiquitin independent degradation ubiquitin-proteasome system WASp interacting protein |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557334303321 |
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Monti Simona Maria
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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