Asymmetry in Biological Homochirality |
Autore | Hochberg David |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
Descrizione fisica | 1 electronic resource (102 p.) |
Soggetto topico | Research & information: general |
Soggetto non controllato |
biochirality
post-translational modifications protein folding protein aggregation spontaneous chemical reactions neurodegeneration non-equilibrium phase transitions chiral symmetry breaking entropy production closed systems nonequilibrium dissipative structures mirror symmetry breaking biological chirality liquid crystals proto-RNA networks compartmentalization chiral liquids cubic phases prebiotic chemistry chirality amplification helical self-assembly chiral oscillations spontaneous mirror symmetry breaking origin of homochirality absolute asymmetric synthesis biological homochirality chemical abiotic evolution chirality origin of life dissipative reaction systems |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557779003321 |
Hochberg David | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Molecular Therapies for Inherited Retinal Diseases |
Autore | Collin Rob W.J |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (262 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences |
Soggetto non controllato |
induced pluripotent stem cell (iPSC)
clustered regularly interspaced short palindromic repeats (CRISPR) homology-directed repair (HDR) Enhanced S-Cone Syndrome (ESCS) NR2E3 AAV retina gene therapy dual AAV gold nanoparticles DNA-wrapped gold nanoparticles ARPE-19 cells retinal pigment epithelium clathrin-coated vesicles endosomal trafficking retinitis pigmentosa autosomal dominant G56R putative dominant negative effect gapmer antisense oligonucleotides allele-specific knockdown Leber congenital amaurosis and allied retinal ciliopathies CEP290 Flanders founder c.4723A > T nonsense mutation Cilia elongation spontaneous nonsense correction AON-mediated exon skipping microRNA photoreceptors rods cones bipolar cells Müller glia retinal inherited disorders retinal degeneration antisense oligonucleotides Stargardt disease inherited retinal diseases splicing modulation RNA therapy ABCA4 iPSC-derived photoreceptor precursor cells cyclic GMP apoptosis necrosis drug delivery systems translational medicine Usher syndrome Leber congenital amaurosis RPE65 nonprofit patient registry translational protein trafficking protein folding protein degradation chaperones chaperonins heat shock response unfolded protein response autophagy therapy IRD DNA therapies RNA therapies compound therapies clinical trials Retinitis Pigmentosa GTPase Regulator adeno-associated viral Retinitis Pigmentosa (RP) choroideremia REP1 inherited retinal disease treatment apical polarity crumbs complex fetal retina PAR complex retinal organoids retinogenesis gene augmentation adeno-associated virus (AAV) |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910674051103321 |
Collin Rob W.J | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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The Conformational Universe of Proteins and Peptides: Tales of Order and Disorder |
Autore | Leone Marilisa |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
Descrizione fisica | 1 electronic resource (230 p.) |
Soggetto topico | Research & information: general |
Soggetto non controllato |
mass spectrometric epitope mapping
gas phase immune complex dissociation apparent gas phase dissociation constants apparent gas phase activation energies ITEM-TWO native mass spectrometry TRIOBP cancer deafness hearing loss mental illness schizophrenia actin cytoskeleton disordered structure protein aggregation solid-state NMR ELDOR-detected NMR ATP hydrolysis ATP analogues DnaB helicase ABC transporter biopesticides antifungal activity insecticidal activity mechanism of action transgenic crops protein folding NMR High Hydrostatic Pressure ACE2 viral spike receptor-binding domain SARS-CoV-2 transmission bioinformatics IDP 1 binding 2 molecular dynamics 3 MELD×MD 4 advanced sampling 5 p53 6 MDM2 7 NAD(P)H-dependent oxidoreductase zinc-containing alcohol dehydrogenase cofactor binding and release interdomain cleft dynamics molecular dynamics simulations denatured state ensemble protein coil library peptides intrinsically disordered proteins ion-pairing interaction side-chain length charged amino acids β-hairpin peptide Friedman's test backbone atom coordinate variances and uncertainties superimposition nanobody protein structure immunoglobulin domain |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Conformational Universe of Proteins and Peptides |
Record Nr. | UNINA-9910557371103321 |
Leone Marilisa | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Transcriptome and Genome Analyses Applied to Aquaculture Research |
Autore | Pereiro Patricia |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (554 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences Fisheries & related industries |
Soggetto non controllato |
RNA-Seq
lncRNAs Dicentrarchus labrax viral infection nodavirus immune response fish T lymphocytes infection malnutrition inflammation aquaculture histopathology immunohistochemistry enteromyxosis Philasterides dicentrarchi turbot transcriptomics Chinese mitten crab Eriocheir sinensis transportome transporters salinity osmoregulation transcriptome meta-analysis gills short pentraxins c-reactive protein zebrafish transcript expression antiviral SVCV rag1 mutants skin mucosal immunity hypoxia hypo-metabolic state growth swimming performance metabolic landmarks muscle transcriptome glycolysis lipid metabolism protein turnover gilthead sea bream hepatopancreas necrosis disease metatranscriptomics sequencing hepatopancreatic flora teleost B cells single cell transcriptomics immunoglobulins immune markers transcription factors long non-coding RNAs hepatic transcript expression salmon microarray omega-6/omega-3 ratio nutrigenomics fatty acids liver muscle Misgurnus anguillicaudatus sexual size dimorphism polyploid size dimorphism comparative transcriptome gene expression edible red sea urchin Loxechinus albus RNA-seq reference transcriptome Chinese soft-shelled turtle Aeromonas hydrophila hemorrhagic sepsis molecular immunopathogenesis tripartite motif proteins B30.2 domain antiviral immunity Ctenopharyngodon idella grass carp reovirus metamorphosis brain RNA sequencing intermuscular bone development Megalobrama amblycephala Oreochromis niloticus histological structure Atlantic salmon smoltification genome mRNAs miRNAs sox family genes Pelodiscus sinensis estradiol pseudo-female sex-related heterosis heterobeltiosis environment transgressive genes conserved miRNA high-throughput sequencing lumpfish novel miRNA RT-qPCR heat shock protein co-chaperon network salinity-alkalinity adaptation molecular evolution Lateolabrax maculatus genomics stress response HPI-axis neuroendocrine-immune interaction common carp poly-unsaturated fatty acid fatty acid elongase association study genomic selection bulked segregant analysis SNP association analysis joint effect seawater adaptation microRNAs small-RNA sequencing microarray transcriptome European seabass chronic inflammation opioid receptors immune status whole-transcriptome sequencing sex differentiation non-coding RNAs ceRNA red cusk-eel thermal stress liver transcriptome oxidative damage protein folding hepatic enzymes |
ISBN | 3-0365-5921-3 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910637793503321 |
Pereiro Patricia | ||
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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