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Anticancer Inhibitors
| Anticancer Inhibitors |
| Autore | Fantacuzzi Marialuigia |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (216 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
breast cancer
tamoxifen LY294002 synergism apoptosis cell cycle tea (Camellia sinensis) flowers BTFS A2780/CP70 ovarian cancer cells S phase cell cycle arrest nicotinamide phosphoribosyltransferase NAD+ biosynthesis inhibitor azacyclohexane anticancer drug drug design enthalpy effect NSCLC Cathepsin K cell proliferation cell migration cell invasion mTOR isatin-hydrazones cytotoxicity CDK2 inhibitor ATP competitive inhibitor ADME analysis receptor tyrosine kinases protein-protein interactions protein engineering directed evolution angiogenesis binding affinity agonistic activity saponins phytochemicals tea (Camellia sinensis) flower ovarian cancer autophagy ZMYND8 tumorigenesis epigenetic regulation pro-oncogenic effects tumor suppression tacrine-coumarin derivatives DNA topoisomerases I, II lung carcinoma cells A549 chemotherapy prodrug drug targeting overexpressed enzymes ADC ADEPT GDEPT LEAPT PROTAC cyclin-dependent kinase cancer resistance small molecule inhibitors PROTACs statins pancreatic cancer DNA microarray pitavastatin cerivastatin simvastatin fluvastatin atorvastatin pravastatin HMG-CoA reductase inhibitors |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595069203321 |
Fantacuzzi Marialuigia
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bacteriophages : Alternatives to Antibiotics and Beyond
| Bacteriophages : Alternatives to Antibiotics and Beyond |
| Autore | Suárez Pilar García |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (390 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
Aeromonas hydrophila
Aeromonas salmonicida agent based American Foulbrood antibacterial antibiotic antibiotic resistance Antibiotic-resistant bacteria antibiotics antimicrobial antimicrobial agent antimicrobial resistance antimicrobials aquaculture bacterial phage resistance bacteriophage bacteriophage therapy bacteriophages Bacteriophages biofilm biofilms biological control Brevibacillus laterosporus bystander phage therapy CBD-independent challenge trials Clostridium difficile Clostridium difficile infection CRISPR CAS dairy industry diabetic foot ulcer directed evolution dual-species endolysin enzybiotics evolution fermentation failure fish larvae FoldX furunculosis horizontal gene transfer, transduction in vitro fermentation model infrared spectroscopy interactions Kayvirus lactic acid bacteria lysin lysins lysogenic conversion lytic enzyme marine vibrios MAS mass action microbiome microbiome therapy models Motile Aeromonas Septicemia MRSA multiple-antibiotic-resistance mycobacteriophages Mycobacterium smegmatis Nagoya Protocol one health osteomyelitis Paenibacillus larvae pathogens peptidoglycan hydrolase phage phage display phage isolation phage resistance phage therapy phage-resistant mutants PlyC CHAP prophage induction protein engineering protein net charge proteins Pseudomonas aeruginosa read recruitment regression modeling resistance safety sequential shiga toxin simultaneous Staphylococcus Staphylococcus aureus STEC O145 strains STEC-specific bacteriophage striped catfish (Pangasianodon hypophthalmus) synergy treatment Vibrio anguillarum vibriosis whole genome sequencing |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Bacteriophages |
| Record Nr. | UNINA-9910557641503321 |
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Suárez Pilar García
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Enzymatic Bioelectrocatalysis
| Enzymatic Bioelectrocatalysis |
| Autore | Lojou Elisabeth |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (176 p.) |
| Soggetto topico |
Industrial chemistry and chemical engineering
Technology: general issues |
| Soggetto non controllato |
biocatalytic reactors
bioelectrocatalysis bioelectrocatalysts bioelectrochemistry bioelectrosynthesis biofuel cells carbon nanomaterials catalysis direct electron transfer electrochemical reactors electrochemistry electrode modification electron transfer enzyme gold electrode hybrid vesicles liposomes membrane protein metallic nanostructures metalloenzyme microbial electrosynthesis n/a nanostructured electrodes orientation oxidoreductase oxidoreductases photo-bioelectrocatalysis photosynthesis protein engineering self-assembled molecular monolayers stability surface modification |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566458303321 |
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Lojou Elisabeth
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Enzyme-Mediated Stereoselective Synthesis
| Enzyme-Mediated Stereoselective Synthesis |
| Autore | Serra Stefano |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (116 p.) |
| Soggetto topico | Chemistry |
| Soggetto non controllato |
?-transaminases
1 1-phenylethanol 4-diols agro-industrial side stream alcohol dehydrogenases alcohol-dehydrogenase aroma compounds asymmetric synthesis biocatalysis bioreduction Burkholderia cepacia lipase chiral amines chiral resolution cyclization diketones enantioselective synthesis enantioselectivity enzyme-mediated resolution esters flavors hydratase hydroxy fatty acids immobilization kinetic resolution Lactobacillus rhamnosus lactones linalool linaloyl oxide linoleic acid linolenic acid linseed cake lipases monoterpenes multi-enzymatic cascades n/a nitroketone oleic acid protein engineering pullulan rapeseed cake reaction engineering reduction solid-state fermentation stereoselective biotransformation |
| ISBN | 3-03921-937-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367738803321 |
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Serra Stefano
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Information Theory in Molecular Evolution: From Models to Structures and Dynamics
| Information Theory in Molecular Evolution: From Models to Structures and Dynamics |
| Autore | Morcos Faruck |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (135 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
allostery
bacterial signaling Brownian process catalytic mechanism chaos co-evolution coevolutionary analysis conformational changes contact prediction cumulative sum DD-transpeptidase direct coupling analysis direct-coupling analysis elastic network model entropy epistasis evolution evolutionary coupling analysis fitness landscape interaction specificity Kolmogorov complexity maximum entropy models monofractal mutational phenotypes n/a non-linear PBP-A phosphorylation phylogenetic bias phylogeny power law protein conformational dynamics protein contact predictions protein engineering sequence analysis sequence reweighting specificity determining contacts statistical inference TEM-1 TOHO-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Information Theory in Molecular Evolution |
| Record Nr. | UNINA-9910557351503321 |
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Morcos Faruck
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy
| Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy |
| Autore | Ruvo Menotti |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (278 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
adoptive immunotherapy
affibody molecules affinity aggregation AL amyloidosis amyloid anti-CD38 MoAb antibody antibody fragment antibody fragments Antibody-Drug Conjugate antibody-drug conjugates BCMA belantamab mafodotin bispecific bispecific T-cell engager blood-brain barrier cancer therapy CAR adaptor CD38 cDNA CHI3L1 chimeric antigen receptor (CAR T) chimeric antigen receptor T-cells cross-linking Daratumumab developability drug targeting E. coli Fab glutamate carboxypeptidase II guinea pig idecabtagene vicleucel immunization immunogenicity in vivo imaging Isatuximab JNJ-68284528 lung metastasis Mabs modular CAR T monoclonal antibodies monoclonal antibody myeloma NAALADase neurodegenerative disorders neurotoxicity non-specific binding nucleocapsid NUsc1 oligomer payload phage display pharmacokinetics polyspecificity porcine deltacoronavirus prostate cancer prostate-specific membrane antigen protein engineering protocol receptor-mediated transcytosis scFv self-association single chain solubility specificity split CAR stability transferrin receptor universal CAR T universal immune receptor viscosity YKL-40 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557613003321 |
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Ruvo Menotti
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Enzyme and Whole-Cell Biocatalysts
| Novel Enzyme and Whole-Cell Biocatalysts |
| Autore | Sunna Anwar |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (332 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
2-keto-3-deoxygluconate
2G ethanol 5-hydroxymethylfurfural 5-hydroxymethylfuroic acid aldohexose dehydrogenase Antarctica and homology modelling archaea artificial neural network asymmetric synthesis Bacillus subtilis lipase A bio-based chemicals bioactive peptides biocatalysis biodiesel biotransformation carbohydrate active enzymes carbohydrates cell immobilization cell surface display cell-free biocatalysis cell-free systems chemo-enzymatic synthesis chiral amine cofactor biosynthesis cofactor F420 cyclodextrin glucanotransferases deazaflavin DNase endo-β-1,3-glucanase ene reductase engineered Escherichia coli enzyme immobilization enzyme sourcing esterase extremophile Fervidobacterium flavonoid glucuronides flux optimization fuel properties functionalized magnetic nanoparticles gene duplication Glaciozyma antarctica glycolysis glycosidase glycoside hydrolase glycoside hydrolases glycosyl transferases hemicellulose usage hormone-sensitive lipase hydride transfer hydrogenation hydrolase immobilization immobilized lipase industrial enzymes interfacial activation keratin hydrolysis keratin waste keratinase kinetic profile kinetic profiles Lactobacillus laminarinase large-ring cyclodextrins lipase lipase immobilization LysM domains machine learning mannonate dehydratase mannono-1,4-lactone mannose metabolism metabolic pathways optimization metalloprotease multienzyme whole-cell biocatalyst natural and non-natural multi-enzyme pathways NDM-24 New Delhi metallo-β-lactamase old yellow enzyme organic solvent organic solvents oxidoreductase peptidase platform chemicals protein engineering psychrophilic yeast RNase RSM S. cerevisiae Saccharolobus solfataricus secondary structure semi rational mutagenesis semi-rational mutagenesis serine protease SHIF solvent stability substrate specificity Sulfolobus solfataricus synthetic biology Thermoplasma acidophilum thermostable thermostable enzymes thioglycosides transesterification valorisation waste cooking oil water activity whole cells α-methylbenzylamine β-galactosidase ω-transaminase |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557108903321 |
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Sunna Anwar
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Synthetic DNA and RNA Programming
| Synthetic DNA and RNA Programming |
| Autore | O'Donoghue Patrick |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (188 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
alanyl-tRNA synthetase
alternative amino acid and nucleotide repertoires alternative core cellular chemistries amber stop codon suppression anticodon ASKA collection AspRS biocontainment biopharmaceuticals branched-chain amino acids class II aminoacyl-tRNA synthetase codon bias CUG-Ser cyclic peptides DNA delivery Escherichia coli expanded genetic code fluorescence-based screen fluorescent reporter functional conservation gene ontology gene overexpression genetic code expansion genetic firewall genetic isolation genetic tools genome editing genome engineering genome synthesis GluRS-like growth effect indirect tRNA aminoacylation live cell imaging lysine acetylation M. jannaschii orthogonal pair Metschnikowia microRNA microRNA quantification misacylation mistranslation mRNA display non-canonical amino acids optogenetics orthogonal central dogma of molecular biology phosphoinositide dependent kinase 1 phosphoseryl-tRNA synthetase posttranslational modification protein engineering protein kinase B protein modification recombinant protein production release factor 1 reverse polymerization RNA metabolism selenocysteine small molecule drug screening synthetic biology synthetic life transfer RNA tRNA tRNA editing tRNA repair tRNASep tRNASer unnatural amino acids unnatural nucleotides xenobiology yeast two hybrid yeasts |
| ISBN | 3-03921-735-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367744503321 |
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O'Donoghue Patrick
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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