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Anticancer Inhibitors
| Anticancer Inhibitors |
| Autore | Fantacuzzi Marialuigia |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (216 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
breast cancer
tamoxifen LY294002 synergism apoptosis cell cycle tea (Camellia sinensis) flowers BTFS A2780/CP70 ovarian cancer cells S phase cell cycle arrest nicotinamide phosphoribosyltransferase NAD+ biosynthesis inhibitor azacyclohexane anticancer drug drug design enthalpy effect NSCLC Cathepsin K cell proliferation cell migration cell invasion mTOR isatin-hydrazones cytotoxicity CDK2 inhibitor ATP competitive inhibitor ADME analysis receptor tyrosine kinases protein-protein interactions protein engineering directed evolution angiogenesis binding affinity agonistic activity saponins phytochemicals tea (Camellia sinensis) flower ovarian cancer autophagy ZMYND8 tumorigenesis epigenetic regulation pro-oncogenic effects tumor suppression tacrine-coumarin derivatives DNA topoisomerases I, II lung carcinoma cells A549 chemotherapy prodrug drug targeting overexpressed enzymes ADC ADEPT GDEPT LEAPT PROTAC cyclin-dependent kinase cancer resistance small molecule inhibitors PROTACs statins pancreatic cancer DNA microarray pitavastatin cerivastatin simvastatin fluvastatin atorvastatin pravastatin HMG-CoA reductase inhibitors |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595069203321 |
Fantacuzzi Marialuigia
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bacteriophages : Alternatives to Antibiotics and Beyond
| Bacteriophages : Alternatives to Antibiotics and Beyond |
| Autore | Suárez Pilar García |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (390 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
bacteriophages
dairy industry pathogens lactic acid bacteria fermentation failure biofilms antimicrobial resistance antimicrobials lysins horizontal gene transfer, transduction biofilm phage therapy resistance bacteriophage models agent based mass action bacterial phage resistance regression modeling MRSA Clostridium difficile Clostridium difficile infection microbiome in vitro fermentation model marine vibrios biological control aquaculture interactions vibriosis Aeromonas hydrophila Motile Aeromonas Septicemia MAS multiple-antibiotic-resistance striped catfish (Pangasianodon hypophthalmus) endolysin antibiotics one health protein engineering Aeromonas salmonicida furunculosis phage-resistant mutants proteins infrared spectroscopy lysin lytic enzyme peptidoglycan hydrolase antimicrobial antibacterial antibiotic resistance bacteriophage therapy Nagoya Protocol CRISPR CAS phage isolation phage resistance Staphylococcus Kayvirus Vibrio anguillarum fish larvae challenge trials phage display enzybiotics Bacteriophages diabetic foot ulcer osteomyelitis Staphylococcus aureus Antibiotic-resistant bacteria lysogenic conversion prophage induction read recruitment shiga toxin American Foulbrood phage Paenibacillus larvae Brevibacillus laterosporus treatment safety bystander phage therapy Mycobacterium smegmatis mycobacteriophages directed evolution PlyC CHAP protein net charge CBD-independent FoldX STEC-specific bacteriophage whole genome sequencing STEC O145 strains antimicrobial agent Pseudomonas aeruginosa dual-species antibiotic synergy simultaneous sequential microbiome therapy evolution |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Bacteriophages |
| Record Nr. | UNINA-9910557641503321 |
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Suárez Pilar García
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Enzymatic Bioelectrocatalysis
| Enzymatic Bioelectrocatalysis |
| Autore | Lojou Elisabeth |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (176 p.) |
| Soggetto topico |
Technology: general issues
Chemical engineering |
| Soggetto non controllato |
bioelectrocatalysts
oxidoreductases biocatalytic reactors electrochemical reactors bioelectrocatalysis nanostructured electrodes protein engineering bioelectrosynthesis photo-bioelectrocatalysis membrane protein electrode modification biofuel cells photosynthesis liposomes hybrid vesicles microbial electrosynthesis direct electron transfer orientation carbon nanomaterials surface modification self-assembled molecular monolayers electron transfer oxidoreductase gold electrode metallic nanostructures enzyme metalloenzyme catalysis stability electrochemistry bioelectrochemistry |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566458303321 |
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Lojou Elisabeth
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Enzyme-Mediated Stereoselective Synthesis
| Enzyme-Mediated Stereoselective Synthesis |
| Autore | Serra Stefano |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (116 p.) |
| Soggetto non controllato |
enantioselective synthesis
flavors hydroxy fatty acids chiral amines diketones esters oleic acid Burkholderia cepacia lipase multi-enzymatic cascades solid-state fermentation biocatalysis agro-industrial side stream rapeseed cake enzyme-mediated resolution linolenic acid stereoselective biotransformation lipases kinetic resolution 1-phenylethanol linseed cake bioreduction Lactobacillus rhamnosus alcohol-dehydrogenase enantioselectivity hydratase reaction engineering immobilization ?-transaminases linoleic acid cyclization monoterpenes 1 lactones protein engineering asymmetric synthesis alcohol dehydrogenases linaloyl oxide chiral resolution aroma compounds 4-diols pullulan linalool reduction nitroketone |
| ISBN | 3-03921-937-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367738803321 |
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Serra Stefano
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Information Theory in Molecular Evolution: From Models to Structures and Dynamics
| Information Theory in Molecular Evolution: From Models to Structures and Dynamics |
| Autore | Morcos Faruck |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (135 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
power law
Brownian process Kolmogorov complexity entropy chaos monofractal non-linear cumulative sum sequence analysis protein engineering direct coupling analysis evolutionary coupling analysis contact prediction phylogenetic bias phylogeny co-evolution coevolutionary analysis direct-coupling analysis specificity determining contacts sequence reweighting maximum entropy models protein contact predictions TEM-1 TOHO-1 PBP-A DD-transpeptidase conformational changes catalytic mechanism evolution epistasis allostery elastic network model protein conformational dynamics statistical inference mutational phenotypes interaction specificity phosphorylation fitness landscape bacterial signaling |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Information Theory in Molecular Evolution |
| Record Nr. | UNINA-9910557351503321 |
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Morcos Faruck
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy
| Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy |
| Autore | Ruvo Menotti |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (278 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
porcine deltacoronavirus
nucleocapsid monoclonal antibodies neurodegenerative disorders affibody molecules blood–brain barrier receptor-mediated transcytosis transferrin receptor AL amyloidosis CD38 anti-CD38 MoAb Daratumumab Isatuximab myeloma BCMA bispecific T-cell engager antibody-drug conjugates chimeric antigen receptor T-cells belantamab mafodotin idecabtagene vicleucel JNJ-68284528 Mabs Antibody-Drug Conjugate cancer therapy drug targeting payload cross-linking antibody fragment Fab scFv E. coli YKL-40 CHI3L1 monoclonal antibody phage display lung metastasis prostate-specific membrane antigen in vivo imaging prostate cancer glutamate carboxypeptidase II NAALADase immunization antibody protocol guinea pig cDNA chimeric antigen receptor (CAR T) universal CAR T modular CAR T universal immune receptor CAR adaptor adoptive immunotherapy split CAR bispecific polyspecificity pharmacokinetics solubility aggregation viscosity developability stability affinity specificity protein engineering self-association non-specific binding immunogenicity antibody fragments single chain amyloid oligomer neurotoxicity NUsc1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557613003321 |
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Ruvo Menotti
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Enzyme and Whole-Cell Biocatalysts
| Novel Enzyme and Whole-Cell Biocatalysts |
| Autore | Sunna Anwar |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (332 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
2G ethanol
hemicellulose usage S. cerevisiae enzyme immobilization cell immobilization SHIF mannonate dehydratase mannose metabolism Thermoplasma acidophilum mannono-1,4-lactone 2-keto-3-deoxygluconate aldohexose dehydrogenase cyclodextrin glucanotransferases large-ring cyclodextrins semi rational mutagenesis carbohydrate active enzymes archaea glycosidase Sulfolobus solfataricus Saccharolobus solfataricus Lactobacillus β-galactosidase immobilization cell surface display LysM domains biocatalysis extremophile 5-hydroxymethylfurfural 5-hydroxymethylfuroic acid platform chemicals whole cells New Delhi metallo-β-lactamase NDM-24 kinetic profile secondary structure glycoside hydrolase thioglycosides Fervidobacterium endo-β-1,3-glucanase laminarinase thermostable gene duplication cofactor F420 deazaflavin oxidoreductase hydride transfer hydrogenation asymmetric synthesis cofactor biosynthesis ω-transaminase α-methylbenzylamine chiral amine biotransformation biodiesel waste cooking oil lipase immobilization interfacial activation functionalized magnetic nanoparticles DNase kinetic profiles RNase semi-rational mutagenesis substrate specificity engineered Escherichia coli flavonoid glucuronides multienzyme whole-cell biocatalyst organic solvents psychrophilic yeast hormone-sensitive lipase Glaciozyma antarctica Antarctica and homology modelling keratinase serine protease metalloprotease peptidase keratin hydrolysis keratin waste valorisation bioactive peptides ene reductase enzyme sourcing old yellow enzyme solvent stability machine learning flux optimization artificial neural network synthetic biology glycolysis metabolic pathways optimization cell-free systems hydrolase lipase esterase Bacillus subtilis lipase A transesterification organic solvent water activity immobilized lipase RSM fuel properties chemo-enzymatic synthesis glycosyl transferases protein engineering carbohydrates industrial enzymes thermostable enzymes glycoside hydrolases cell-free biocatalysis natural and non-natural multi-enzyme pathways bio-based chemicals |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557108903321 |
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Sunna Anwar
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Synthetic DNA and RNA Programming
| Synthetic DNA and RNA Programming |
| Autore | O'Donoghue Patrick |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (188 p.) |
| Soggetto non controllato |
growth effect
lysine acetylation Escherichia coli posttranslational modification class II aminoacyl-tRNA synthetase amber stop codon suppression genetic code expansion yeasts phosphoseryl-tRNA synthetase M. jannaschii orthogonal pair gene ontology selenocysteine genetic firewall indirect tRNA aminoacylation tRNA editing unnatural nucleotides reverse polymerization RNA metabolism genome editing tRNA tRNASer alternative amino acid and nucleotide repertoires biocontainment fluorescent reporter optogenetics tRNASep GluRS-like genetic isolation live cell imaging alternative core cellular chemistries fluorescence-based screen phosphoinositide dependent kinase 1 synthetic biology mistranslation tRNA repair synthetic life CUG-Ser unnatural amino acids recombinant protein production biopharmaceuticals protein modification functional conservation branched-chain amino acids alanyl-tRNA synthetase release factor 1 cyclic peptides AspRS xenobiology DNA delivery gene overexpression non-canonical amino acids ASKA collection protein kinase B codon bias microRNA quantification anticodon small molecule drug screening mRNA display genetic tools protein engineering misacylation transfer RNA Metschnikowia genome synthesis expanded genetic code yeast two hybrid orthogonal central dogma of molecular biology microRNA genome engineering |
| ISBN | 3-03921-735-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367744503321 |
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O'Donoghue Patrick
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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