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Albumin-Based Drug Delivery Systems
| Albumin-Based Drug Delivery Systems |
| Pubbl/distr/stampa | Basel : , : MDPI - Multidisciplinary Digital Publishing Institute, , 2022 |
| Descrizione fisica | 1 electronic resource (162 pages) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
plasma half-life extension
albumin conjugation in vivo glucose-lowering activity glucagon-like peptide-1 quality by design rapid equilibrium dialysis muco-adhesion brain PAMPA RPMI 2650 nasal epithelial cell human serum albumin dimerization doxorubicin enhanced permeability and retention effect antitumor Arthrobacter globiformis gout half-life extension inverse electron demand Diels-Alder reaction site-specific albumin conjugation thermostability urate oxidase albumin anti-thrombotic CD39 coating of medical devices stent coating therapeutic fusion protein conjugates vanadium cancer prodrug hydrogels EPR/ESR spectroscopy release behavior disulfide glioma conjugate albumin binding moieties peptides Evans blue 4-(p-iodophenyl)butyric acid integrin αvβ6 integrin αvβ6 binding peptide improved pharmacokinetics PET imaging |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576888003321 |
| Basel : , : MDPI - Multidisciplinary Digital Publishing Institute, , 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Anticancer Agents : Design, Synthesis and Evaluation
| Anticancer Agents : Design, Synthesis and Evaluation |
| Autore | Chen Qiao-Hong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (606 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
benzofurans
chemical synthesis cytotoxic properties HeLa MOLT-4 K562 anticancer anti-neuroinflammation coumarin dihydroartemisinin flavonoids allene E-stereoselective regioselective anti-cancer activity cyanopyridone substituted pyridine pyridotriazine pyrazolopyridine thioxotriazopyridine anticancer activity HepG2 antitumor activity computational docking MDM2-p53 interaction xanthones yeast-based assays estrone derivatives hydrazine N-substituted pyrazoline anti-ovarian cancer topoisomerase II inhibitor kinase inhibitor antiproliferative agent urea synthesis antiproliferative activity apoptosis indoleamine 2,3-dioxygenase inhibitor anti-tumor immune modulation tryptophan metabolism taxoids βIII-tubulin P-glycoprotein drug resistance thiopene thienopyrimidinone thiazolidinone breast cancer benzofuran–pyrazole nanoparticles cytotoxic activity PARP-1 inhibition 3,6-dibromocarbazole 5-bromoindole carbazole actin migration Thienopyrimidine Pyrazole PI3Kα inhibitor quinazolin-4(3H)-one quinazolin-4(3H)-thione Schiff base antioxidant activity DFT study ortho-quinones beta-lapachone tanshione IIA PI3Ks PI3Kδ inhibitors 2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide anticancer agents protein–protein interactions virtual screening mimetics drug discovery bivalency polyvalency antitumor cell cycle ovarian cancer P-MAPA IL-12 TLR signaling inflammation chemoresistance 4-(pyridin-4-yloxy)benzamide 1,2,3-triazole c-Met natural product anticancer agent zampanolide Talazoparib PARP inhibitor prodrug o-nitro-benzyl photoactivatable protecting groups salinomycin overcoming drug resistance tumor specificity synergy 5-fluorouracil gemcitabine amides/esters colchicine analogs thiocolchicine colchiceine antimitotic agents hydrates dihydropyranoindole HDAC inhibitors neuroblastoma aromatase MCF-7 NIH3T3 benzimidazole triazolothiadiazine docking ADME organosilicon compounds SILA-409 (Alis-409) SILA-421 (Alis-421) multidrug resistance (MDR) reversal ABCB1 (P-glycoprotein) colon cancer colchicine amide colchicine sulfonamide tubulin inhibitors docking studies crystal structure PROTACs protein degradation IGF-1R Src protein kinase phenylpyrazolopyrimidine enzyme inhibition molecular simulation androgen receptor prostate cancer enzalutamide apalutamide darolutamide triple-negative breast cancer cytotoxicity chrysin analogues flavonoid anticancer compounds |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Anticancer Agents |
| Record Nr. | UNINA-9910557129103321 |
Chen Qiao-Hong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Anticancer Inhibitors
| Anticancer Inhibitors |
| Autore | Fantacuzzi Marialuigia |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (216 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
breast cancer
tamoxifen LY294002 synergism apoptosis cell cycle tea (Camellia sinensis) flowers BTFS A2780/CP70 ovarian cancer cells S phase cell cycle arrest nicotinamide phosphoribosyltransferase NAD+ biosynthesis inhibitor azacyclohexane anticancer drug drug design enthalpy effect NSCLC Cathepsin K cell proliferation cell migration cell invasion mTOR isatin-hydrazones cytotoxicity CDK2 inhibitor ATP competitive inhibitor ADME analysis receptor tyrosine kinases protein-protein interactions protein engineering directed evolution angiogenesis binding affinity agonistic activity saponins phytochemicals tea (Camellia sinensis) flower ovarian cancer autophagy ZMYND8 tumorigenesis epigenetic regulation pro-oncogenic effects tumor suppression tacrine-coumarin derivatives DNA topoisomerases I, II lung carcinoma cells A549 chemotherapy prodrug drug targeting overexpressed enzymes ADC ADEPT GDEPT LEAPT PROTAC cyclin-dependent kinase cancer resistance small molecule inhibitors PROTACs statins pancreatic cancer DNA microarray pitavastatin cerivastatin simvastatin fluvastatin atorvastatin pravastatin HMG-CoA reductase inhibitors |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595069203321 |
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Fantacuzzi Marialuigia
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Delivery of Molecules Using Nanoscale Systems for Cancer Treatment and/or Diagnosis
| Delivery of Molecules Using Nanoscale Systems for Cancer Treatment and/or Diagnosis |
| Autore | Franco Marina Santiago |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (302 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
nanostructured lipid carriers
doxorubicin mucositis cell internalization albumin BSA CPP gold nanorods gold nanoprisms arginine-rich peptide glutathione nanoparticles oxidative stress breast cancer gastric cancer nanoparticle fucoidan d-alpha-tocopherylpoly (ethylene glycol) succinate combination chemotherapy G-quadruplex nucleolin DNA nanocages intracellular localization cancer targeting molecular dynamics simulations mesoporous silica nanoparticles radiotherapy immunotherapy tumor microenvironment abscopal effect magnetofection in vivo magnetic nanoparticles iron oxide gene delivery gene vectors codelivery nanocarriers photodynamic therapy anticancer therapies combination therapy phthalocyanine uterine cervical neoplasms photochemotherapy in vitro in vivo nanocarrier polyplexes siRNA delivery glioblastoma therapy amphiphilic poly(α)glutamate P-selectin prodrug drug delivery targeted therapy chemotherapy prostate cancer prostate-specific membrane antigen targeted delivery encapsulation cabazitaxel nanocarriers nanosystems radiosensitizer hypoxia synergism cancer photothermal therapy combined antitumor effect oxygenation hydrogel hypoxic tumor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595074103321 |
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Franco Marina Santiago
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Emerging Role of Lipids in Metabolism and Disease
| Emerging Role of Lipids in Metabolism and Disease |
| Autore | Pallottini Valentina |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (308 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
neutral sphingomyelinase
radiation sphingomyelin metabolism pathology cell signaling brain adipose tissue breast cancer epinephrine breast reconstruction epicardial fat thickness visceral fat thickness high-sensitivity c-reactive protein leptin gender female hippocampus frontal cortex adiponectin haptoglobin lipocalin BDNF synaptic proteins phosphatidylinositol 4,5-bisphosphate phospholipase C cholesterol high-cholesterol diet BET proteins cell proliferation epigenetics HMGCR JQ1 LDLr lipid metabolism SREBP TMEM97 atherosclerosis diabetes mellitus cardiovascular disease chronic inflammation hyperglycemia mutations lipid fatty acid glyceride steroid phospholipid oral drug absorption prodrug phospholipase A2 (PLA2) acid sphingomyelinase SOD liver eicosanoids ischemic stroke ischemia lipoproteins polyunsaturated fatty acids angiogenesis high-density lipoprotein endothelial cell metabolism metabolic reprogramming pulmonary fibrosis lipid mediators sphingolipids sphingosine-1-phosphate sphingosine kinase 1 prostaglandins lysophosphatidic acid autotaxin G-protein coupled receptors lysocardiolipin acyltransferase phospholipase D oxidized phospholipids DNA damage response double strand breaks ATM ionizing radiation metabolic stress oxidative stress p53 nuclear sphingolipids lipophagy lipolysis lipid droplets lipid storage diseases lipid metabolism diseases mTORC1 TFEB Cholesterol Fatty acids Lipid mediators Lipids Lipophagy Sphingolipids |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557800303321 |
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Pallottini Valentina
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Anti-cancer Agents and Cellular Targets and Their Mechanism(s) of Action
| Novel Anti-cancer Agents and Cellular Targets and Their Mechanism(s) of Action |
| Autore | Allison Simon J |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (206 p.) |
| Soggetto topico |
Technology: general issues
History of engineering & technology |
| Soggetto non controllato |
microtubule acetylation
triple-negative breast cancer anti-cancer agent apoptosis K562 8-hydroxydaidzein autophagy BCR-ABL MAPK NF-κB c-myc RNA interference siRNA oncogene gene silencing expression nanosystems Cytochrome P450 CYP1A1 CYP1B1 CYP2W1 breast cancer prodrug bioprecursor duocarmycin phortress AQ4N 5-FU resistance colorectal cancer drug repurposing Genomics of Drug Sensitivity in Cancer Connectivity Map anticancer drug B-lactam steroid alkylators synthetic lethality poly (ADP-ribose) polymerase inhibitors ovarian cancer hybrid steroidal alkylating agents migration invasion glioblastoma CCN1 mesenchymal-amoeboid transition biomarker HepG2 Huh7 isatin sulfonamides angiogenesis cancer hallmarks molecular docking EGFR tyrosine kinase inhibitor photon upconversion triplet-triplet annihilation in vivo imaging PLGA nanoparticles affibody molecule human epidermal growth factor receptor 3 (HER3) BxPC-3 emtansine DM1 albumin binding domain affibody drug conjugate (AffiDC) |
| ISBN | 3-0365-5222-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Novel Anti-cancer Agents and Cellular Targets and Their Mechanism |
| Record Nr. | UNINA-9910619465503321 |
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Allison Simon J
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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