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Marine Compounds and Cancer 2020
| Marine Compounds and Cancer 2020 |
| Autore | Honecker Friedemann |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (480 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
apoptosis
fucoidan hepatocellular carcinoma reactive oxygen species 3-alkylpyridinium polymers nicotine nicotinic acetylcholine receptor non-small cell lung carcinoma melanoma sinulariolide proteomic mitochondria caspase cascade marine fungus sediment anthranilic acid Penicillium paneum cytotoxicity dibromotyrosine mitochondrial dysfunction oxidative stress topoisomerase epigonal organ bonnethead shark Jurkat tumor cell line hippuristanol PEL AP-1 STAT3 Akt colorectal cancer marine mollusc brominated indoles shrimp chemoprevention fatty acids carotenoids cancer nanoparticle osteosarcoma lung metastasis elisidepsin lipid rafts hydroxylated lipids fatty acid 2-hydroxylase cooperative binding membrane permeabilization marine organisms polysaccharides anticancer anticarcinogenic mechanisms of action fumigaclavine C anti-proliferation mitochondrial pathway anti-cancer anti-proliferative carotenoid cell cycle arrest fucoxanthin azoxymethane bioactive natural product isatin in vivo model Marthasterias glacialis L. palmitic acid ER-stress CHOP Antibody Drug Conjugates (ADCs) marine antitumor agents clinical trials approved antitumor agents AD0157 angiogenesis marine drug pyrrolidinedione secondary metabolites cancer preventive chemopreventive trabectedin plitidepsin tumor-associated macrophages tumor microenvironment preclinical anticancer immunity antiangiogenesis fascaplysin cyclin-dependent kinase small cell lung cancer camptothecin poly(ADP-ribose)-polymerase inhibitor breast cancer seaweed therapeutic compounds autophagy marine drugs autophagy inhibitors autophagy inducers macrolide programmed cell death energy stress araguspongine C c-Met HER2 gemcitabine pazopanib phase I safety soft tissue sarcoma pachastrissamine jaspine B carbocyclic analogue sphingosine kinase inhibitor molecular modeling ET-743 DNA minor groove binder soft tissue sarcoma chemotherapy bis (2,3-dibromo-4,5-dihydroxy-phenyl)-methane (BDDPM) anti-metastatic activity cell adhesion β1-integrin FAK BEL-7402 cell triterpene glycosides sea cucumbers antitumor activities arrest of cell cycle antibacterial marangucyclines deep-sea Streptomyces sp. SCSIO 11594 LS-1 SNU-C5/5-FU TGF-β signaling carcinoembryonic antigen kalkitoxin Moorea producens mitochondria toxin VEGF angiogenesis inhibitor hypoxia-inducible factor-1 HIF-1 Lyngbya majuscula marine metabolites SZ-685C nonfunctioning pituitary adenomas Ecklonia cava phlorotannins dieckol migration sipholenol A ABC transporter multidrug resistance P-gp/ABCB1 BCRP/ABCG2 MRP1/ABCC1 marine natural products glioblastoma xyloketal B proliferation TRPM7 marine compound ribosomal protein genes snoRNA FAU RPS30 SNORA62 evolution Porifera Penicillium brevicompactum Brevianamide Mycochromenic acid derivative antifouling Caribbean sponge plakortide endoperoxide leukemia multi-drug resistant leukemia Sarcophyton ehrenbergi soft coral terpenes cembranoids cytotoxic activity molecular docking uveal melanoma oxidative stress virtual screening Topo I inhibitor low toxic natural product Ulva fasciata selenium-containing polysaccharide-protein complex pseudopterosin NF-κB p65 inflammation cytokine release IL-6 TNFα MCP-1 glucocorticoid receptor paulomycins Micromonospora antitumor Cantabrian Sea-derived actinobacteria puupehenones sponges antiangiogenic antitumoral porifera/sponge cancer genes molecular oncology bromophenol molecular mechanisms cell cycle PI3K/Akt p38/ERK ROS human lung cancer glycosaminoglycans antiproliferative heparan sulphate gliotoxin NSCLC adriamycin resistance Sepia ink polysaccharides antitumour chemosensitization anticoagulation sea anemone drug discovery endothelial cells RGD motif kunitz type inhibitor prostate cancer antioxidant natural marine compounds marine biotechnology microalgae marine sponges Aeroplysinin Isofistularin pheochromocytoma and paraganglioma metastasis cancer progression cell adhesion molecules integrin β1 hypoxia phycocyanin non-small cell lung cancer NF-κB signaling marine-derived drugs bioanalysis chromatography manzamine A epithelial-mesenchymal transition lung cancer circulating tumor cells signal transduction cisplatin Lampetra morii buccal gland cystatin F anti-angiogenesis cystatin superfamily Antimicrobial peptide (AMP) Tilapia piscidin 4 (TP4) non-small cell lung cancer (NSCLC) itampolin A FBDD p38α novel inhibitor tetracenomycin X cyclin D1 proteasomal degradation p38 c-JUN λ-carrageenan heparanase anticoagulant depolymerisation cell migration Aspergillus naphthopyrones endophytic fungus Leathesia nana mangrove-derived actinomycete ansamycins divergolides apoptosis-inducing activity actinomycin EMT invasion low molecular weight fucoidan extract N-Ras neuroblastoma-rat sarcoma Cancer programmed cell death-ligand 1 programmed cell death-ligand 2 human sarcoma cell line (HT1080 cells) human normal diploid fibroblast (TIG-1 cells) chimera chemical conjugation anticancer agent hybridization α9-nicotinic acetylcholine receptors (nAChRs) breast cancer cells αO-conotoxin GeXIVA targeted therapy gorgonian Leptogorgia humulane sesquiterpenoids anticancer activity 12-deacetyl-12-epi-scalaradial HeLa cells Nur77 MAPK/ERK pathway Mycalin A C15 acetogenins synthetic analogues antiproliferative activity A375 and HeLa cell lines polyoxygenated steroids sponge Haliclona gracilis Thalassia testudinum thalassiolin B polyphenols CYP1A1 benzo[a]pyrene JNK1/2 natural products synergism A549 cells cytoskeleton P2X7 receptor pollution anti-angiogenic gene expression HSP90 inhibitor |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557339303321 |
Honecker Friedemann
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Insights into Parvovirus Research
| New Insights into Parvovirus Research |
| Autore | Gallinella Giorgio |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (342 p.) |
| Soggetto non controllato |
antivirals
Bombyx mori bidensovirus Bocaparvovirus human bocavirus 1 equine parvovirus-hepatitis NS2 NS1 X-ray crystallography BIRC3 (cIAP-2) glycans children antibody interactions new viruses alpaca cidofovir rodent protoparvoviruses clinical trials structural biology DNA virus human bocavirus caspase-3 viral communities uncoating PLA2 phospholipase-A2 oncolytic virus immune therapy Parvoviridae viral ecology Cryo-EM AAV metagenomics phylogeny oncolytic viruses mite parvovirus evolution Carnivore protoparvovirus 1 adeno-associated virus telbivudine capsid stability virus homology modeling human airway epithelia sequence analysis acute gastroenteritis bisulfite PCR next-generation sequencing single stranded DNA virus overlapping promoters virus diversity prognosis oncolytic activity genome hydroxyurea Lepidoptera genome externalization antiviral compounds circulating angiogenic cells tumor microenvironment coumarin derivatives nuclear targeting densovirus receptor interactions cell cycle arrest transcription profile brincidofovir canine parvovirus endogenous viral elements inflammatory cardiomyopathy erythroid progenitor cells RNA-seq insect chapparvovirus RT-qPCR trafficking AAV2 agricultural pests Adeno-associated virus myocarditis diagnosis parvovirus feline panleukopenia virus chitin B19V transcription mapping flavonoids immunomodulation erythrovirus apoptosis adenoviral vector anti-cancer divalent cations protease genetics preclinical arthropod peritrophins biocontrol dilated cardiomyopathy insect parvovirus combination therapies intravenous immunoglobulin (IVIG) virus phylogeny evolution second generation parvovirus treatments commercial horse serum parvovirus B19 canine chapparvovirus CpG methylation RACE H-1PV viral metagenomics horses |
| ISBN | 3-03928-311-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404088603321 |
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Gallinella Giorgio
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pre-Clinical Models of PTSD
| Pre-Clinical Models of PTSD |
| Autore | Liberzon Israel |
| Pubbl/distr/stampa | Frontiers Media SA, 2019 |
| Descrizione fisica | 1 electronic resource (194 p.) |
| Soggetto topico |
Science: general issues
Neurosciences |
| Soggetto non controllato |
PTSD
pre-clinical animal models preclinical |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557595803321 |
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Liberzon Israel
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| Frontiers Media SA, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Transmucosal Absorption Enhancers in the Drug Delivery Field
| Transmucosal Absorption Enhancers in the Drug Delivery Field |
| Autore | Maher Sam |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (406 p.) |
| Soggetto non controllato |
chitosan
intestinal epithelial cells ocular delivery amphiphilic polymers cornea tight junction modulator cyclodextrin permeability gemini surfactant transferrin compound 48/80 epithelial permeability cervicovaginal tumors nanoparticles confocal laser scanning microscopy safety formulation salcaprozate sodium intestinal absorption FITC-dextran curcumin block copolymers nasal vaccination whole leaf brush border ocular drug delivery vaccine adjuvant nanoparticle nasal delivery efflux permeation enhancers absorption enhancers nose to brain delivery small intestine epithelium CNS disorders absorption modifying excipients insulin absorption enhancer gel intestinal delivery thermogel system Caco-2 biocompatibility studies absorption enhancement man PN159 poorly absorbed drug tryptophan tight junction oral macromolecule delivery penetration enhancer intestinal permeation enhancers nanocrystals simvastatin nanomedicine enterocyte N-dodecyl-?-D-maltoside (DDM) cell-penetrating peptide quaternization KLAL nasal nasal permeability transmucosal drug delivery Caco-2 cells mast cell activator penetration enhancers drug delivery nose-to-brain bioenhancer polymeric micelles mucoadhesion cell-penetrating peptide (CPP) simulated intestinal fluid vaginal delivery nasal formulation pharmacokinetic interaction sodium caprate clinical trial transmucosal permeation drug absorption enhancer sugar-based surfactants nanocapsules imatinib teriparatide osteoporosis hydrophobization F-actin combined microsphere transepithelial electrical resistance oral delivery ocular conditions metabolism antimicrobial peptide permeation enhancer drug administration antiepileptic drug amino acid in vivo studies sodium cholate (NaC) epithelial transport preclinical nose to brain transport pharmacokinetics chitosan derivatives ophthalmology tight junctions sheep cationic functionalization GLP-1 pulmonary and liposome cytochrome P450 claudin P-glycoprotein in situ hydrogel mucoadhesiveness PTH 1-34 Aloe vera oral peptides |
| ISBN | 3-03921-849-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910372785603321 |
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Maher Sam
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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