Info
- Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.
Ion Channels as Marine Drug Targets
| Ion Channels as Marine Drug Targets |
| Autore | Sabatier Jean-Marc |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (134 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
antiarrhythmics
bioactives botulinum toxin A1 chemotherapy chitosan nanoparticles conantokins conotoxin conotoxins 2 Conus tulipa electrically induced arrhythmia guanidine alkaloid intraspecific variation ion channel modulators Kv1 latent TB mammalian NaV channel marine anti-TB compounds marine toxins modulators MTB net hunting strategy neuropathic pain nicotinic nirvana cabal paclitaxel pharmacological models of arrhythmia potassium channels proteomics PZA saxitoxin sea anemone toxins selective inhibitor sponges T-type CaV3.2 taxane transcriptomics TxVIA venomics voltage-gated sodium channel zetekitoxin AB α9α10 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557396203321 |
Sabatier Jean-Marc
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Mitochondrial Transport Proteins
| Mitochondrial Transport Proteins |
| Autore | Palmieri Ferdinando |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (476 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
22.q11.2
ABC transporter adult-onset type II citrullinemia (CTLN2) amino acid animal model apoptosis aquaporin argininosuccinate synthetase (ASS) aspartate/glutamate carrier (AGC) ATP ATP synthase ATP synthase oligomers mitochondrial cristae morphology ATP-dependent potassium channel aversion to carbohydrates bioenergetics biological function Ca2+ signaling calcium cancer carnitine carnitine acyl-carnitine carrier carnitine acyl-carnitine translocase carrier CIC citrate citrin cofactor CTP cyclophilin D cyclosporin A diabetes disease diseases electrophysiology error of metabolism food taste function gene promoter glucolipotoxicity glucose-induced expression glucose-stimulated insulin secretion glucotoxicity hypoxia inflammation inner mitochondrial membrane ion ion channels ischemia/reperfusion isoforms LETM lifespan lipotoxicity MCF MCU membrane subunits of ATP synthase membrane transport metabolic disorders metabolism metabolite transport mitochondria mitochondrial biogenesis mitochondrial Ca2+ uniporter mitochondrial Ca2+-induced permeability transition pore mitochondrial calcium transport mitochondrial calcium uniporter complex mitochondrial carrier mitochondrial carrier disease mitochondrial carrier family mitochondrial carriers mitochondrial disease mitochondrial metabolism mitochondrial permeability transition mitochondrial pyruvate carrier mitochondrial transport mitochondrial transporter MPC mutation NAD NAD+ transporters NAFLD/NASH necrosis neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD) neurodegeneration organic acid oxidative post-translational modification pancreatic islets peroxisomes plant development plant metabolism post-translational modification potassium channel openers potassium channels protein targeting protein translocation protein-protein interaction pyruvate metabolism resistance to hypoxia ROS sequence analysis sideroflexin skeletal muscle mitochondria SLC transporters SLC25 SLC25A1 SLC25A20 SLC25A51 SLC54 SLC55 SLC56 solute carrier family 25 substrate specificity TIM chaperones TIM22 TOM transport mechanism USMG5/DAPIT VDAC1 virus vitamin Voltage-Dependent Anion selective Channel yeast β-cell |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566465303321 |
|
Palmieri Ferdinando
|
||
| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Opioids and Their Receptors : Present and Emerging Concepts in Opioid Drug Discovery
| Opioids and Their Receptors : Present and Emerging Concepts in Opioid Drug Discovery |
| Autore | Spetea Mariana |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (358 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
(−)-N-phenethylnorhydromorphone analogs
[35S]GTPgammaS assay [Dmt1]DALDA 14-methoxycodeine-6-O-sulfate 1H-NMR experiments 6β-naltrexol abuse agonist allodynia analgesia analgesics antagonist arrestin recruitment beta-arrestin bias factor biased agonism biased agonist biased agonists biased ligands biased signaling bifunctional ligands binding binding affinity BNTX buprenorphine chronic constriction injury (CCI) codeine codeine-6-O-sulfate DADLE DALDA DAMGO delta opioid receptor dependence design and synthesis dihydrocodeine diphenethylamines docking dysbiosis fentanyl forskolin-induced cAMP accumulation assays functional assay G-protein bias heteromer hyperalgesia interaction fingerprints internalization inverse agonist ischemia kappa opioid receptor KGOP01 Leu-enkephalin loperamide lysosomes macrocyclic tetrapeptide mechanism elucidation misuse mitragynine molecular docking molecular dynamics molecular modeling & MOR and DOR agonists morphinan morphine mu opioid receptor mu receptor multifunctional ligands n/a naltrexone neonatal opioid withdrawal syndrome neurokinin-1 receptor neutral antagonist NTI derivative opioid opioid drugs opioid liabilities opioid peptide opioid peptides opioid peptides and peptidomimetics opioid receptors opioid side effects opioids over-the-counter drugs pain therapy partial agonism partial agonist peptide synthesis peripheral analgesic tolerance peripheral antinociception peripheral µ-opioid receptors pharmacology plasma stability potassium channels primary hippocampal culture PZM21 racemic synthesis of β2-amino acids receptor binding studies receptor model respiration respiratory depression selectivity simulation SR-17018 structure-activity relationships sulfonamide TAPP tolerance writhing test zerumbone β-arrestin recruitment assays β2-amino acids β2-Homo-amino acids δ opioid receptor δ opioid receptor antagonist μ opioid receptor µ opioid receptor µ-opioid receptor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Opioids and Their Receptors |
| Record Nr. | UNINA-9910557108003321 |
|
Spetea Mariana
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||