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DNA Replication Stress / Robert M. Brosh
| DNA Replication Stress / Robert M. Brosh |
| Autore | Brosh Robert M |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (368 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
Werner Syndrome
A549 cells epigenetic neurodegeneration Genome integrity adaptation cellular senescence genome instability Werner Syndrome Protein lipofuscin cell cycle checkpoints exonuclease 1 template-switching energy metabolism mutation frequency DNA replication fork regression motor neuron disease Microsatellites Alzheimer's disease chromatin remodeler repair of DNA damage AP site analogue mutagens replication timing Thermococcus eurythermalis nucleolar stress gene expression mutations spectra origin firing Fanconi Anemia superfamily 2 ATPase DNA translocation DNA repair SSB signaling homologous recombination common fragile sites 8-chloro-adenosine replication genome stability mutagenicity fork reversal multiple sclerosis non-B DNA protein stability heterogeneity ubiquitin SenTraGorTM (GL13) replication restart EdU ?-arrestin NER aging SSB end resection oxidative stress ATR dormant origins R loops DNA damage response Difficult-to-Replicate Sequences DNA double-strand repair endonuclease IV ALS double strand break repair premature aging replication stress EXO1 POL? translesion synthesis strand displacements G2-arrest DNA replication pattern SSB repair genome integrity G protein-coupled receptor kinase interacting protein 2 (GIT2) MMR replicative stress senolytics spacer interactome ATR-Chk1 DDR pathway C9orf72 replication fork restart translesion DNA synthesis DNA damage mismatch repair DNA replication stress DNA helicase Polymerase kappa DNA fiber assay H1299 cells TLS APE2 ageing cell death chromosome TopBP1 barley clock proteins post-translational modification 8-oxoG S phase ataxia telangiectasia mutated (ATM) G protein-coupled receptor (GPCR) Polymerase eta cancer G protein-coupled receptor kinase (GRK) helicase genomic instability Parkinson's disease nucleotide excision repair SupF |
| ISBN |
9783039213900
3039213903 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367564903321 |
Brosh Robert M
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Dual Specificity Phosphatases: From Molecular Mechanisms to Biological Function
| Dual Specificity Phosphatases: From Molecular Mechanisms to Biological Function |
| Autore | Pulido Rafael |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (240 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
asthma
astrocytes atypical dual-specificity phosphatases atypical DUSP BDNF brain metastasis cancer cannabinoids circulating tumor cells (CTCs) COPD Cpp1 cytokines DEPArray differentiation dual-specificity phosphatase dual-specificity phosphatases DUSP-4 DUSP10 E. coli infection fungal MKPs granule neurons HDAC6 (histone deacetylase isoform 6) hematopoietic cells HER2 hypertriglyceridemia inflammation influenza integrated omics analysis liver steatosis macrophage macrophages MAP Kinase Phosphatase-2 MAP kinase phosphatases MAP kinases MAPK MAPK phosphatase MAPKs microtubules mitogen-activated protein kinase MK-STYX (MAPK (mitogen-activated protein kinase) phosphoserine/threonine/tyrosine-binding protein) Mkp-1 Msg5 n/a neuroblastoma neuronal differentiation nucleotide receptors P2X7 P2Y13 Pmp1 post-translational modification proliferation protein stability pseudophosphatase respiratory viruses rhinovirus RSV Sdp1 sepsis signaling single cell analysis T cell TLR signaling triple-negative breast cancer (TNBC) ubiquitination |
| ISBN | 3-03921-689-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Dual Specificity Phosphatases |
| Record Nr. | UNINA-9910367740903321 |
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Pulido Rafael
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Functionally Relevant Macromolecular Interactions of Disordered Proteins
| Functionally Relevant Macromolecular Interactions of Disordered Proteins |
| Autore | Simon Istvan |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (520 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
aggregation
CABS model co-evolution coarse-grained conformational plasticity copper binding correlated mutations decision tree based artificial neural network dehydron differentially regulated genes disorder-to-order regions disordered protein disordered protein platform DNA conformational landscape DNA-protein interactions drug discovery drugs dual threshold eIF4E epiproteome evolution evolutionary couplings extracellular FG-Nups fluorescence anisotropy folding functional analysis gene ontology analysis histone lysine methyltransferase homodimer HOTAIR hydration hydrogen bond immune inter-subunit interaction interaction surface intrinsic disorder intrinsic disorder prediction intrinsically disorder proteins intrinsically disordered intrinsically disordered protein intrinsically disordered proteins intrinsically disordered proteins (IDPs) intrinsically disordered region ion pair leukemia lncRNA MC simulations MEG3 membrane-less organelle meta strategy Microarray MLL proteins MLL4 molecular machines molecular recognition feature molten globule mutual synergistic folding N-terminal prion protein neurodegenerative disease neurodegenerative diseases Nuclear pore complex oligomer p300 HAT acetylation p53 phosphorylation physiological homeostasis plant virus post-translational modification post-translational modifications potyvirus prion disease mutations protein protein aggregation protein conformation protein hydrodynamics protein intrinsic disorder protein stability protein structure protein thermostability protein-protein interaction protein-RNA interactions residue co-variation residue contact network ribosomal protein RIN4 RNA binding RNA sequencing salt bridges secretion sequential DNA bending significance voting smFRET solvent-accessible surface area Sox2 sequential DNA loading spectroscopy stabilization center statistical force fields stress response structural disorder structural domain Tau fibrillation temperature response transcription factor dosage transcription factors transcriptome unstructured proteins VPg wide-line 1H NMR |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557509403321 |
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Simon Istvan
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitochondrial Transport Proteins
| Mitochondrial Transport Proteins |
| Autore | Palmieri Ferdinando |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (476 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
22.q11.2
ABC transporter adult-onset type II citrullinemia (CTLN2) amino acid animal model apoptosis aquaporin argininosuccinate synthetase (ASS) aspartate/glutamate carrier (AGC) ATP ATP synthase ATP synthase oligomers mitochondrial cristae morphology ATP-dependent potassium channel aversion to carbohydrates bioenergetics biological function Ca2+ signaling calcium cancer carnitine carnitine acyl-carnitine carrier carnitine acyl-carnitine translocase carrier CIC citrate citrin cofactor CTP cyclophilin D cyclosporin A diabetes disease diseases electrophysiology error of metabolism food taste function gene promoter glucolipotoxicity glucose-induced expression glucose-stimulated insulin secretion glucotoxicity hypoxia inflammation inner mitochondrial membrane ion ion channels ischemia/reperfusion isoforms LETM lifespan lipotoxicity MCF MCU membrane subunits of ATP synthase membrane transport metabolic disorders metabolism metabolite transport mitochondria mitochondrial biogenesis mitochondrial Ca2+ uniporter mitochondrial Ca2+-induced permeability transition pore mitochondrial calcium transport mitochondrial calcium uniporter complex mitochondrial carrier mitochondrial carrier disease mitochondrial carrier family mitochondrial carriers mitochondrial disease mitochondrial metabolism mitochondrial permeability transition mitochondrial pyruvate carrier mitochondrial transport mitochondrial transporter MPC mutation NAD NAD+ transporters NAFLD/NASH necrosis neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD) neurodegeneration organic acid oxidative post-translational modification pancreatic islets peroxisomes plant development plant metabolism post-translational modification potassium channel openers potassium channels protein targeting protein translocation protein-protein interaction pyruvate metabolism resistance to hypoxia ROS sequence analysis sideroflexin skeletal muscle mitochondria SLC transporters SLC25 SLC25A1 SLC25A20 SLC25A51 SLC54 SLC55 SLC56 solute carrier family 25 substrate specificity TIM chaperones TIM22 TOM transport mechanism USMG5/DAPIT VDAC1 virus vitamin Voltage-Dependent Anion selective Channel yeast β-cell |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566465303321 |
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Palmieri Ferdinando
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Modeling and Simulation of Lipid Membranes
| Modeling and Simulation of Lipid Membranes |
| Autore | Marti Jordi |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (174 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Biochemistry |
| Soggetto non controllato |
peptide
MD GUV LUV azo-amino acid KRas-4B mutation post-translational modification HVR anionic plasma membrane signaling cholesterol model membranes molecular dynamics calorimetry Schiff base imine benzimidazole 2,4-dihydroxybenzaldehyde neutron reflectometry X-ray reflectometry small-angle neutron scattering small-angle X-ray scattering molecular dynamics simulations scattering length density profile phospholipid membrane phosphatidylserine cancer cells MD simulation membrane permeability withaferin A withanone CAPE artepillin C membrane elasticity red blood cells hemodynamics hemorheology microfluidics benzothiadiazine derivatives drug design KCNE3 structural dynamics lipid bilayers molecular dynamics simulation membrane mimetic |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595071503321 |
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Marti Jordi
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nitric Oxide Signaling in Plants
| Nitric Oxide Signaling in Plants |
| Autore | Hancock John |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (170 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
antioxidants
Arabidopsis thaliana benzyl viologen catalase cell enlargement cell proliferation cue1/nox1 diaphorase activity early flowering electrophile germination hydrogen gas hydrogen peroxide hydrogen sulfide lichens lipid peroxidation methyl viologen microalgae molybdenum cofactor monodehydroascorbate reductase NIA1 NIA2 nitrate nitrate reductase nitration nitric oxide nitric oxide homeostasis nitric oxide synthase nitrite nitro-fatty acids nitro-lipid-protein adducts nitroalkenes nitroalkylation nitrogen dioxide nitrogen metabolism NO analyzer NOFNiR nucleophile peroxisome plant growth post-translational modification PsbO reactive lipid species reactive nitrogen species reactive oxygen species root development S-(hydroxymethyl)glutathione S-nitrosation S-nitrosoglutathione reductase S-nitrosothiols S-nitrosylation signaling mechanism SNO-reductase stress responses sugar metabolism superoxide dismutase thiol modification Trebouxia tyrosine nitration |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557117803321 |
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Hancock John
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Natural-based Biomolecules Discovery for Tackling Chronic Diseases
| Novel Natural-based Biomolecules Discovery for Tackling Chronic Diseases |
| Autore | Kwok Hang Fai |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (180 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
AKT
amphibian Bowman-Birk inhibitor amyloidogenesis anionic lipids anti-inflammation anticancer therapy anticancer therapy/cancer treatment antifungal antioxidant apoptosis Asteraceae Astragalus membranaceus Bcl-2 family proteins binding affinity branched-chain fatty acids cell cycle arrest colorectal cancer Conidiobolus heterosporus COX-2 DAPK1 docetaxel drug delivery system drug design endoplasmic reticulum F23R variant fatty acid oxidation fibroblasts fucoidan G-protein activation gingiva hepatocyte hIAPP iNOS insulin insulin granules kynurenines lignan lipid metabolism lung cancer molecular cloning molecular docking n/a natural-based compound NO orientin PDX-1 peptides peroxisome proliferator-activated receptor α Petasites japonicus PGE2 pharmacophore PI3K PLGA pomegranate post-translational modification PPARγ protease inhibitor protein degradation punicalagin SENP STAT3 SUMO survivin tannins Tat peptide unfolded protein response wound healing β-cell cytotoxicity β-sheet transitions μ-opioid receptor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557607403321 |
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Kwok Hang Fai
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Post-transcriptional Regulation through Long Noncoding RNAs (lncRNAs)
| Post-transcriptional Regulation through Long Noncoding RNAs (lncRNAs) |
| Autore | Ladomery Michael |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (156 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
alternative splicing
antisense transcript cancer ceRNAs CLIP database double-stranded RNA (dsRNA) gene expression innate immunity interactome lncRNA lncRNAs long non-coding RNA long non-coding RNA 1 long non-coding RNAs long noncoding RNA microRNA miRNAs mRNA stability mTOR pathway n/a ncRNAs non-coding RNAs post-transcription post-transcriptional regulation post-translational modification prediction protein re-localization repetitive DNA elements (RE) ribonucleoprotein RNA binding protein RNA binding protein 2 RNA-binding RNAi splicing factors target mimicry translation translation promotion |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Post-transcriptional Regulation through Long Noncoding RNAs |
| Record Nr. | UNINA-9910557367803321 |
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Ladomery Michael
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Structure, Activity, and Function of Protein Methyltransferases
| Structure, Activity, and Function of Protein Methyltransferases |
| Autore | Jeltsch Albert |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (292 p.) |
| Soggetto topico |
Biochemistry
Biology, life sciences Research & information: general |
| Soggetto non controllato |
actin
actin cytoskeleton AML arginine methylation cancer cardiovascular disease cell proliferation cell signaling chromatin regulation congenital heart diseases cytoskeleton dendritic spine diabetes disease DNA damage repair dystonia eEF1A EHMT1 EHMT2 enteroviruses enzyme regulation enzyme specificity epigenetics G9a GLP GTPase H3K36 H3K36me2 H3K4me3 H3K9 methylation H3R2me2a H4R3 methylation heterochromatin histone Hsmar1 Huntington's disease immunity inflammation inflammatory bowel disease lysine methylation lysine-specific methyltransferase (PKMT) methyltransferase Metnase METTL13 MLL2 N-terminal methylation n/a neurodegenerative diseases neuron NHEJ non-homologous end joining repair NSD1 NSD3 NUP98-NSD1 oncogenesis PKMT pluripotency polymerization post translational modification post-translational modification post-translational protein modification posttranslational modifications Prader-Willi syndrome PRMT1 PRMT2 PRMT5 PRMT6 PRMT7 protein arginine methylation protein histidine methylation protein lysine methylation protein post-translational modification Rett syndrome schizophrenia SET7/9 SETD3 SETD7 SETDB1 SETMAR SH3 SOTOS stress response structure structure and function synapse transcriptional regulation translation transposable elements transposase WHSC1L1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566479603321 |
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Jeltsch Albert
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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