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Clinical Utility of Applying PGx and Deprescribing-Based Decision Support in Polypharmacy : Future Perspectives
| Clinical Utility of Applying PGx and Deprescribing-Based Decision Support in Polypharmacy : Future Perspectives |
| Autore | Vermehren Charlotte |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (224 p.) |
| Soggetto topico |
Medicine
Pharmaceutical industries |
| Soggetto non controllato |
acute kidney injury
early biomarker plasma neutrophil gelatinase-associated lipocalin soluble urokinase plasminogen activator receptor medication optimization older patients emergency department multimorbidity polypharmacy potentially inappropriate medication use older adults prevalence determinants chronic outpatient 2019 Beers criteria Ethiopia pharmacogenomics persons with diabetes drug–drug interactions drug–gene interactions cytochrome P450 SLCO1B1 drug interaction checkers adverse drug reactions pharmacogenetics personalized medicine phenprocoumon DOACs bleeding thromboembolism HLA drug hypersensitivity abacavir allopurinol flucloxacillin antiepileptic drugs cost-effectiveness shared medication record medication reconciliation drug information service hospital pharmacy service electronic prescribing electronic medical record clinical pharmacist CYP2D6 CYP2D7P CYP2D8P copy number variation CNV genotyping 5’nuclease assay HRM high resolution melting drug metabolization extracellular vesicles exosomes microvesicles pharmacogene expression medication review deprescriptions quality of life aged aged, 80 and over nursing homes deprescribing medication-based risk score health outcomes cytochromes CYP1A2 adverse drug reaction antipsychotics olanzapine clozapine loxapine children youth digital decision-support health services research general practice process evaluation antidepressants utility population-based appropriateness medication adherence digital health |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Clinical Utility of Applying PGx and Deprescribing-Based Decision Support in Polypharmacy |
| Record Nr. | UNINA-9910595072903321 |
Vermehren Charlotte
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Computational and Experimental Approaches in Multi-Target Pharmacology
| Computational and Experimental Approaches in Multi-Target Pharmacology |
| Autore | Thomas J. Anastasio |
| Pubbl/distr/stampa | Frontiers Media SA, 2017 |
| Descrizione fisica | 1 electronic resource (122 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
systems biology
computer modeling drug repurposing synergy drug discovery drug combination high throughput screening multidrug therapeutics polypharmacy multifactorial process |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910261143503321 |
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Thomas J. Anastasio
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| Frontiers Media SA, 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Drug-Drug Interactions
| Drug-Drug Interactions |
| Autore | Kim Dong Hyun |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (242 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
tadalafil
ticagrelor drug-drug interaction pharmacokinetics plasma concentration CYP3A4 Loxoprofen CYP3A Dexamethasone Ketoconazole CYP2D6 O-desmethyltramadol physiologically-based pharmacokinetics tramadol (‒)-sophoranone CYP2C9 potent inhibition in vitro in vivo drug interaction low permeability high plasma protein binding biflavonoid cytochrome P450 drug interactions selamariscina A uridine 5′-diphosphoglucuronosyl transferase tissue-specific systemic exposure P-glycoprotein (P-gp) organic anion transporting polypeptide 1A2 (OATP1A2) Rumex acetosa fexofenadine chronic kidney disease drug–drug interactions polypharmacy adverse drug reactions Lexicomp subset analysis signal detection algorithms spontaneous reporting systems mechanism-based inhibition competitive inhibition non-competitive inhibition substrate inhibitor cytochromes P450 OATP1B1 OATP1B3 tyrosine kinase inhibitors drug-drug interactions migraine lasmiditan gepants monoclonal antibodies CYP1A1 CYP1A2 drug–drug interaction expression metabolism regulation drug transporter ubiquitination ixazomib DDI computational prediction in silico QSAR drug metabolism ADME CYP metabolic DDI P450 1A2 2B6 2C19 2C8 2C9 2D6 3A4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557666403321 |
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Kim Dong Hyun
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitochondrial Dysfunction in Aging and Diseases of Aging
| Mitochondrial Dysfunction in Aging and Diseases of Aging |
| Autore | Haas Richard H |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (270 p.) |
| Soggetto non controllato |
age-related diseases
sphingolipids glaucoma ALS neurodegeneration mitochondrial dysfunction adaptive immunity senescence de-emergence innate immunity cell danger response mitochondrial transfer axonal transport cytokines mitochondrial age-related macular degeneration prevention heart failure purinergic signaling autophagy Alzheimer's disease diabetic retinopathy proteostasis 1 immunosenescence Miro1 ROS metabolism optic nerve polypharmacy eIF2? Parkin coenzyme Q10 neurodegenerative disease DNA damage skin exercise nucleotide metabolism pasteur effect stress response inflammation retina drug-induced mitochondrial toxicity neuroinflammation exosomes reactive oxygen species 25(OH)D cardiomyopathy crabtree effect insulin resistance cardiovascular disease ageing genetic mutations metabokines mitochondria multiple sclerosis aerobic healing cycle SOD1 mitophagy PINK1 type 2 diabetes integrated cell stress response morbidity and mortality ultraviolet photoageing cancer aging 25(OH)2D lysosome NAD+ Parkinson's disease |
| ISBN | 3-03921-328-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367756303321 |
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Haas Richard H
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Trends in Cognitive Ageing and Mild Cognitive Impairment
| New Trends in Cognitive Ageing and Mild Cognitive Impairment |
| Autore | Facal David |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (130 p.) |
| Soggetto topico | Public health & preventive medicine |
| Soggetto non controllato |
memory loss
virtual reality technology nature environments qualitative research dementia long-term care cognitive aging epidemiology healthcare disparities minority health leisure activity engagement measurement of activity cognitive performance aging adults sustained attention to response task SART multimodal visualization threshold timed up-and-go falls cognition repeated measures mobility decline molecular imaging ICDs 18F-FDG-PET Parkinson's disease dopamine agonists mixed dementia behavioral and psychological symptoms in dementia challenging behaviors lockdown depression adjustment disorder glaucoma hallucinations polypharmacy balance exercise Otago Exercise Program |
| ISBN | 3-0365-5538-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910637778203321 |
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Facal David
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pharmacogenomics : From Basic Research to Clinical Implementation
| Pharmacogenomics : From Basic Research to Clinical Implementation |
| Autore | Scheinfeldt Laura B |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (162 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
pharmacogenomics
return of results genetic counseling qualitative pharmacogenetics implementation pharmacogenetics service screening pre-emptive personalized medicine precision medicine community pharmacy pharmacogenomic testing genetic privacy pharmaco-economics polymorphisms pharmacogenes pharmacogenomic machine learning adaptation human evolution US Food and Drug Administration clinical actionability clinical translation chronic kidney disease CYP3A5 polymorphism progression pharmacogenomics (PGx) pediatrics best practice alerts (BPAs) electronic health records (EHR) genomic indicators clinical decision support (CDS) phenotype genotype polypharmacy chronic disease medication management electronic medical record artificial intelligence |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Pharmacogenomics |
| Record Nr. | UNINA-9910566459103321 |
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Scheinfeldt Laura B
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pharmacy Practice and Administration
| Pharmacy Practice and Administration |
| Autore | Adunlin Georges |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (260 p.) |
| Soggetto topico |
Medicine
Pharmaceutical industries |
| Soggetto non controllato |
older adults
polypharmacy internal medicine ward community pharmacy drug disposal unused medication environment awareness practice ambulatory care facilities health workforce pharmacists Taiwan Commonwealth Partnerships for Antimicrobial Stewardship (CwPAMS) National Health Service (NHS) Chief Pharmaceutical Officer’s Global Health Fellowship CPhOGH Fellows CwPAMS pharmacy fellowship health partnerships antimicrobial resistance (AMR) global health leadership non-prescription medicines emergency contraception community pharmacies information gathering availability pricing mystery calls ulipristal acetate levonorgestrel Germany e-prescription prescription writing Jazan Saudi Arabia prescription errors medicine consumption defined daily dose adolescents and young adults cancer patients fragility pain MUR medication review barriers pharmacist pregabalin abuse community pharmacists reproductive health contraception emergency contraceptives patient education biosensing technology digital medicine system medication adherence medication event monitoring system nonadherence prescription opioids mortality standardized mortality ratio underlying cause of death prescriptions community pharmacy services emergency prescribing pharmacy practice pharmacy law and regulation COVID-19 additional monitoring black triangle adverse event reporting pharmacovigilance intervention outcomes systematic review pharmacy education decision to study in pharmacy selecting pharmacy as a first choice pharmacogenomics learning activity asynchronous learning virtual learning student survey Program of All-Inclusive Care for the Elderly adverse drug events medication-related problems drug-related problems medication safety Medicare Medicaid financial management pharmacy management business entrepreneurship pharmacy students perception attitudes ability interprofessional simulation acute care nursing students standardized patients high fidelity SPICE-R2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585940103321 |
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Adunlin Georges
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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