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ABC Transporters in Human Diseases
| ABC Transporters in Human Diseases |
| Autore | Falguières Thomas |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (494 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
5' untranslated region
AAV ABC ABC (ATP-binding cassette) transporters ABC transporter ABC transporters ABCA subfamily ABCA7 ABCB1 ABCB11 ABCB4 ABCC2 ABCC6 ABCG2 ABCG2 genotype ABCG5 ABCG5/G8 ABCG8 adrenoleukodystrophy Alzheimer's disease amyloid-beta anticancer antifungal resistance atherosclerosis ATP-binding cassette transporter ATP-binding cassette transporter A1 (ABCA1) Aβ peptides BCRP beta-amyloid bile salts bile secretion bioinformatics blood-brain barrier breast cancer BRIC BSEP calcification cAMP cancer cellular ATP efflux chaperones cholesterol cholesterol homeostasis cis-acting elements clinico-genetic analysis competitive allele-specific PCR disease-free survival drug action drug transport dyslipidemia early-onset gout erlotinib ethnic specificity fatty acids functional divergence gall stone gene therapy generalized arterial calcification of infancy genetic variations gout HDL-C homology modeling hyperuricemia intracellular traffic intrahepatic cholestasis invasion MDR3 mechanism mechanism of action membrane protein microparticles migration molecular partners MRP1 MRP4 multidrug resistance multidrug transporter mutagenesis mutations n/a neuron next-generation sequencing NT5E P-glycoprotein peroxisome PET PFIC PFIC2 phagocytosis phosphatidylcholine phytosterol polar relay polymorphisms precision medicine proliferation pseudoxanthoma elasticum Pseudoxanthoma elasticum (PXE) pyrophosphate RAB GTPase rare variant regulatory extension regulatory insertion reverse cholesterol transport Roma serum uric acid single nucleotide polymorphism sitosterolemia SK-N-SH SNP SUA-lowering therapy substrate-binding site tariquidar taxol therapies therapy response TNAP trafficking transport transporter type 2 diabetes urate urate transporter uric acid xenosterol yeast |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674029103321 |
Falguières Thomas
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Adaptive diversification [[electronic resource] /] / Michael Doebeli
| Adaptive diversification [[electronic resource] /] / Michael Doebeli |
| Autore | Doebeli Michael <1961-> |
| Edizione | [Course Book] |
| Pubbl/distr/stampa | Princeton, N.J., : Princeton University Press, 2011 |
| Descrizione fisica | 1 online resource (346 p.) |
| Disciplina | 578.4 |
| Collana | Monographs in population biology |
| Soggetto topico |
Adaptation (Biology) - Mathematical models
Biodiversity - Mathematical models Evolution (Biology) - Mathematical models |
| Soggetto genere / forma | Electronic books. |
| Soggetto non controllato |
LotkaЖolterra models
Maynard Smith model Richard Lenski adaptive diversification adaptive dynamics theory adaptive dynamics adaptive speciation anisogamy asexual speciation assortative mating biological diversity clonal models coevolution coevolutionary dynamics conformist cultures cooperative interactions crossfeeding cultural evolution dispersal rates disruptive selection diverging phenotypic clusters diversification ecological character displacement ecological dynamics ecology ecosystem evolutionary biology evolutionary branching evolutionary dynamics evolutionary processes evolutionary trajectory experimental evolution frequency dependence frequency independence frequency-dependent competition frequency-dependent interactions frequency-dependent selection gamete size individual-based models intraspecific cooperation language memes language mainstream culture mathematical modeling mating populations microbes mutualism mutualistic interactions niche ecology partial differential equation models pattern formation phenotype distributions phenotype phenotypic differentiation phenotypic divergence polymorphic populations polymorphism polymorphisms predation predatorаrey interactions prezygotic reproductive isolation religion religious diversification reproductive isolation resource competition sexual populations sexual reproduction speciation model trophic preference |
| ISBN |
1-283-15248-7
9786613152480 1-4008-3893-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Front matter -- Contents -- Acknowledgments -- CHAPTER ONE. Introduction -- CHAPTER TWO. Evolutionary Branching in a Classical Model for Sympatric Speciation -- CHAPTER THREE. Adaptive Diversification Due to Resource Competition in Asexual Models -- CHAPTER FOUR. Adaptive Diversification Due to Resource Competition in Sexual Models -- CHAPTER FIVE. Adaptive Diversification Due to Predator-Prey Interactions -- CHAPTER SIX. Adaptive Diversification Due to Cooperative Interactions -- CHAPTER SEVEN. More Examples: Adaptive Diversification in Dispersal Rates, the Evolution of Anisogamy, and the Evolution of Trophic Preference -- CHAPTER EIGHT. Cultural Evolution: Adaptive Diversification in Language and Religion -- CHAPTER NINE. Adaptive Diversification and Speciation as Pattern Formation in Partial Differential Equation Models -- CHAPTER TEN. Experimental Evolution of Adaptive Diversification in Microbes -- APPENDIX. Basic Concepts in Adaptive Dynamics -- Bibliography -- Index |
| Record Nr. | UNINA-9910456402603321 |
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Doebeli Michael <1961->
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| Princeton, N.J., : Princeton University Press, 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Adaptive diversification [[electronic resource] /] / Michael Doebeli
| Adaptive diversification [[electronic resource] /] / Michael Doebeli |
| Autore | Doebeli Michael <1961-> |
| Edizione | [Course Book] |
| Pubbl/distr/stampa | Princeton, N.J., : Princeton University Press, 2011 |
| Descrizione fisica | 1 online resource (346 p.) |
| Disciplina | 578.4 |
| Collana | Monographs in population biology |
| Soggetto topico |
Adaptation (Biology) - Mathematical models
Biodiversity - Mathematical models Evolution (Biology) - Mathematical models |
| Soggetto non controllato |
LotkaЖolterra models
Maynard Smith model Richard Lenski adaptive diversification adaptive dynamics theory adaptive dynamics adaptive speciation anisogamy asexual speciation assortative mating biological diversity clonal models coevolution coevolutionary dynamics conformist cultures cooperative interactions crossfeeding cultural evolution dispersal rates disruptive selection diverging phenotypic clusters diversification ecological character displacement ecological dynamics ecology ecosystem evolutionary biology evolutionary branching evolutionary dynamics evolutionary processes evolutionary trajectory experimental evolution frequency dependence frequency independence frequency-dependent competition frequency-dependent interactions frequency-dependent selection gamete size individual-based models intraspecific cooperation language memes language mainstream culture mathematical modeling mating populations microbes mutualism mutualistic interactions niche ecology partial differential equation models pattern formation phenotype distributions phenotype phenotypic differentiation phenotypic divergence polymorphic populations polymorphism polymorphisms predation predatorаrey interactions prezygotic reproductive isolation religion religious diversification reproductive isolation resource competition sexual populations sexual reproduction speciation model trophic preference |
| ISBN |
1-283-15248-7
9786613152480 1-4008-3893-2 |
| Classificazione | SCI088000SCI020000SCI027000 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Front matter -- Contents -- Acknowledgments -- CHAPTER ONE. Introduction -- CHAPTER TWO. Evolutionary Branching in a Classical Model for Sympatric Speciation -- CHAPTER THREE. Adaptive Diversification Due to Resource Competition in Asexual Models -- CHAPTER FOUR. Adaptive Diversification Due to Resource Competition in Sexual Models -- CHAPTER FIVE. Adaptive Diversification Due to Predator-Prey Interactions -- CHAPTER SIX. Adaptive Diversification Due to Cooperative Interactions -- CHAPTER SEVEN. More Examples: Adaptive Diversification in Dispersal Rates, the Evolution of Anisogamy, and the Evolution of Trophic Preference -- CHAPTER EIGHT. Cultural Evolution: Adaptive Diversification in Language and Religion -- CHAPTER NINE. Adaptive Diversification and Speciation as Pattern Formation in Partial Differential Equation Models -- CHAPTER TEN. Experimental Evolution of Adaptive Diversification in Microbes -- APPENDIX. Basic Concepts in Adaptive Dynamics -- Bibliography -- Index |
| Record Nr. | UNINA-9910781692503321 |
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Doebeli Michael <1961->
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| Princeton, N.J., : Princeton University Press, 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biochemical Biomarkers and Neurodegenerative Diseases
| Biochemical Biomarkers and Neurodegenerative Diseases |
| Autore | Ciaccio Marcello |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (156 p.) |
| Soggetto topico |
Medicine and Nursing
Neurosciences |
| Soggetto non controllato |
25(OH)D levels
AD ALS Alzheimer's disease Alzheimer's Disease AMPK amyloid beta amyloid precursor protein amyotrophic lateral sclerosis Arylsulfatase A astrocytes beta amyloid biomarker biomarkers cerebral ischemia essential tremor focused ultrasound FOXP3 Fyn tyrosine kinase GATA3 Gaucher's disease genetic GLUT3 GSK3β GWAS high-intensity focused ultrasound ablation image quality inherited neuromuscular disorders iron lysosomes magnetic resonance imaging MCAO MR-guided focused ultrasound multiple sclerosis n/a nervous system neurodegenerative disease neurodegenerative diseases neurodegenerative nisease neuroinflammation neuromelanin nigrosome-1 Parkinson's disease parkinsonian disorders PD polymorphisms prognostic biomarker radiomics rare diseases resveratrol SARS-CoV-2 stereotaxic techniques Tyr682 residue vitamin D Vitamin D Vitamin D deficiency YENPTY motif |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557361103321 |
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Ciaccio Marcello
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cytochromes P450: Drug Metabolism, Bioactivation and Biodiversity 2.0
| Cytochromes P450: Drug Metabolism, Bioactivation and Biodiversity 2.0 |
| Autore | Dansette Patrick M |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (286 p.) |
| Soggetto topico | Research and information: general |
| Soggetto non controllato |
20-HETE
active site access channels Antibiotics arachidonic acid azole drugs Bacillus Bietti's crystalline dystrophy biosynthetic gene clusters cavities boundaries circulatory CYPs comparative analysis cryptococcus cryptococcus neoformans crystal structure Cyanobacteria CYP diversity analysis CYP128A1 CYP139A1 CYP2C8 CYP3A4 CYP4 genes CYP450 CYP51 Cytochrome b5 (CYB5) cytochrome P450 cytochrome P450 monooxygenase cytochrome P450 monooxygenases cytochrome P450 monooxygenenases cytochrome P450 reductase cytochromes P450 cytochromes P450 monooxygenases drug metabolism electron transfer electron-transfer (ET) enzyme substrate specificity exosomes extracellular vesicles extrahepatic tissues fatty acid fungal pathogens gene-cluster diversity percentage genetic polymorphisms genome data mining genome data-mining host metabolism human pathogens isoform lamellar ichthyosis mathematical formula mechanism-based inhibitor membrane protein menaquinone metabolism microsomal cytochrome P450 (CYP) minimal cost paths molecular dynamic simulations molecular dynamics simulation molecular functionality mutagenesis Mycobacterium Mycobacterium tuberculosis Mycobacterium tuberculosis H37Rv NADPH-cytochrome P450 reductase (CPR) non-ribosomal peptides P450 blooming P450 diversity percentage P450 profiling paclitaxel phylogenetic analysis plasma polyketides polymorphisms precision Cardio-Oncology precision medicine protein dynamics protein-membrane interactions protein-protein interaction reactive oxygen species RNA interference secondary metabolites SNPs Sogatella furcifera Streptomyces sulfoxaflor systems medicine terpenes transcriptome tremellomycetes trichosporon tuberculosis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Cytochromes P450 |
| Record Nr. | UNINA-9910557761103321 |
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Dansette Patrick M
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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HLA-G-mediated Immune Tolerance: Past and New Outlooks
| HLA-G-mediated Immune Tolerance: Past and New Outlooks |
| Autore | Silvia Gregori |
| Pubbl/distr/stampa | Frontiers Media SA, 2017 |
| Descrizione fisica | 1 online resource (92 p.) |
| Collana | Frontiers Research Topics |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Autoimmunity
Cancer Exosomes HLA-G Immuno-modulation Infections polymorphisms Pre-Eclampsia Pregnancy tolerance |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | HLA-G-mediated Immune Tolerance |
| Record Nr. | UNINA-9910220053103321 |
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Silvia Gregori
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| Frontiers Media SA, 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Odyssey of Surfactant Proteins SP-A and SP-D: Innate Immune Surveillance Molecules
| Odyssey of Surfactant Proteins SP-A and SP-D: Innate Immune Surveillance Molecules |
| Autore | Kishore Uday |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 online resource (205 p.) |
| Soggetto topico |
Immunology
Medicine and Nursing |
| Soggetto non controllato |
cancer
infection inflammation innate immunity polymorphisms SP-A SP-D |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Odyssey of Surfactant Proteins SP-A and SP-D |
| Record Nr. | UNINA-9910557219903321 |
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Kishore Uday
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pharmacogenomics : From Basic Research to Clinical Implementation
| Pharmacogenomics : From Basic Research to Clinical Implementation |
| Autore | Scheinfeldt Laura B |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (162 p.) |
| Soggetto topico |
Medicine and Nursing
Pharmacology |
| Soggetto non controllato |
adaptation
artificial intelligence best practice alerts (BPAs) chronic disease chronic kidney disease clinical actionability clinical decision support (CDS) clinical translation community pharmacy CYP3A5 electronic health records (EHR) electronic medical record genetic counseling genetic privacy genomic indicators genotype human evolution implementation machine learning medication management n/a pediatrics personalized medicine pharmaco-economics pharmacogenes pharmacogenetics pharmacogenetics service pharmacogenomic pharmacogenomic testing pharmacogenomics pharmacogenomics (PGx) phenotype polymorphism polymorphisms polypharmacy pre-emptive precision medicine progression qualitative return of results screening US Food and Drug Administration |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Pharmacogenomics |
| Record Nr. | UNINA-9910566459103321 |
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Scheinfeldt Laura B
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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