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Novel Treatment Strategies for Glioblastoma
| Novel Treatment Strategies for Glioblastoma |
| Autore | Stylli Stanley |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (268 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
glioblastoma
glioma temozolomide radiotherapy immunotherapy novel therapy personalized treatment drug repurposing invasion invadopodia ion channels gene therapy viral vectors brain tumor nanomedicine cancer stem cell targeted therapy brain cancer cell cycle differentiation proliferation RAS SRGAP2 stem cell TP53 glioblastoma multiforme GBM nerve/glial antigen 2 NG2 CK2 CX-4945 migration CRISPR/Cas9 anticancer anti-angiogenesis thyrointegrin αvβ3 PEG triazole tetrac P-bi-TAT P-m-TAT tetrac one-carbon metabolism de novo purine synthesis metabolic reprogramming metabolic treatment vaccine immune checkpoint inhibitors chimeric antigen receptor (CAR) T cells glioblastoma (GB) prolyl-oligopeptidase (POP) vascular endothelial growth factor (VEGF) transforming growth factor-β (TGF-β) angiopoietin (Ang) endothelial nitric oxide synthase (eNOS) newly diagnosed glioblastoma recurrent glioblastoma new trial design drug-inducible gene expression Mardepodect Regorafenib drug targets tumor antigens renin-angiotensin system pluripotent stem cells organoids cancer stem cells cancer stem cell niche tumor microenvironment |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557363703321 |
Stylli Stanley
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Oligodendrocyte Physiology and Pathology Function
| Oligodendrocyte Physiology and Pathology Function |
| Autore | Kipp Markus |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (330 p.) |
| Soggetto topico |
Medicine
Neurosciences |
| Soggetto non controllato |
plasma membrane proteins
liquid chromatography-mass spectrometry murine acute brain slices reproducibility rat cerebellum Nsun5 Williams-Beuren syndrome (WBS) corpus callosum (CC) oligodendrocyte (OL) myelination remyelination EGFR inhibitor smoothened agonist microfibers drug screening multiple sclerosis cuprizone atrophy design-based stereology 18F-FDG macromolecular proton fraction MPF myelin magnetic resonance imaging cuprizone model demyelination oligodendrocyte precursors oligodendrocytes immunohistochemistry oligodendrocyte epigenetics neurodegeneration laquinimod energy drinks caffeine taurine neuron OPC oligodendrocyte progenitor cells screening nanofibers DigiGait™ experimental autoimmune encephalomyelitis gait analysis schizophrenia interneuron pluripotent stem cells cognition treatment cre-recombinase experimental autoimmune encephalomyelitis (EAE) glial progenitor cells tamoxifen down syndrome white matter glial fate transient receptor potential ankyrin 1 astrocyte conditional knockout astrocytes white matter disease cross-talk CNS glial cells age microglia |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557760203321 |
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Kipp Markus
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Towards Mechanism-based Treatments for Fragile X Syndrome
| Towards Mechanism-based Treatments for Fragile X Syndrome |
| Autore | Kumari Daman |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (250 p.) |
| Soggetto non controllato |
lymphoblast
pluripotent stem cells FMR1 Gene editing X chromosome Fmr1 epigenetic gene silencing FMR1 gene Fragile X syndrome 1 repeat instability characteristics that have the greatest impact DNA instability working memory language development mosaicism CRISPR 3 clinical trials autism spectrum disorders Fmr1 KO mouse automated vocal analysis base excision repair (BER) inhibitory control cerebral spinal fluid iPSC drug development targeted treatments molecular biomarkers viral vector avoidance biomarker set-shifting early identification expansion anxiety planning voice of the person mismatch repair (MMR) gene reactivation double-strand break repair (DSBR) newborn screening intellectual disability processing speed voice of the patient fragile X syndrome adeno-associated virus neurodevelopmental disorders histone methylation Non-homologous end-joining (NHEJ) ASD Fxr2 Fragile X-associated Tremor/Ataxia Syndrome 2 Trinucleotide Repeat 4 CGG Repeat Expansion Disease DNA methylation contraction fragile X mental retardation protein RNA:DNA hybrid behavior developmental disorders cognition females FMRP Fragile X Syndrome unstable repeat diseases protein synthesis brain cognitive flexibility treatment development fibroblast PRC2 transcription coupled repair (TCR) best practices attention Fragile X executive function |
| ISBN | 3-03921-506-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367759103321 |
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Kumari Daman
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Transcriptional Regulation of Cardiac Development and Disease
| Transcriptional Regulation of Cardiac Development and Disease |
| Autore | Wagner Nicole |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (222 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Biochemistry |
| Soggetto non controllato |
pluripotent stem cells
cardiomyocytes cardiac tissue engineering human heart tissue maturation Wilms' tumor suppressor 1 cardiomyocyte differentiation mouse embryonic stem cells myocardial infarction YAP TEAD1 Toll-like receptor heart TLR4 cardiomyocyte innate immune responses Wilms' tumor suppressor 1 (Wt1) cardiac development coronary vessel formation transcriptional regulation cardiac malformation epicardium epicardial derived cells (EPDCs) epithelial mesenchymal transition (EMT) cardiac cell fate regeneration arrhythmogenic cardiomyopathy (ACM) lamin A/C atomic force microscopy (AFM) cell-cell adhesion neonatal rat ventricular fibroblasts (NRVF) tunneling nanotubes (TNT) gene therapy cardiovascular diseases cardiac regeneration cardiac reprogramming therapeutic angiogenesis growth factors reactive oxygen species apoptosis Bmp signaling Hand1 Smad heart development SH3BGR cardiac hypertrophy SRF signaling Hippo signaling cardiomyogenic differentiation cardiac mesenchymal stromal cell hydrogels histone deacetylase inhibitors translational studies gene expression and regulation cardiomyopathy heart failure reverse remodelling left ventricular assist device |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674017103321 |
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Wagner Nicole
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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