Functionally Relevant Macromolecular Interactions of Disordered Proteins |
Autore | Simon Istvan |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (520 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences |
Soggetto non controllato |
intrinsically disordered proteins
epiproteome disordered protein platform molecular recognition feature post-translational modifications physiological homeostasis stress response RIN4 p53 molecular machines intrinsically disordered protein membrane-less organelle neurodegenerative disease p300 HAT acetylation post-translational modification protein aggregation Tau fibrillation intrinsically disorder proteins disorder-to-order regions protein–RNA interactions unstructured proteins conformational plasticity disordered protein folding ribosomal protein spectroscopy protein stability temperature response protein thermostability salt bridges meta strategy dual threshold significance voting decision tree based artificial neural network protein intrinsic disorder intrinsic disorder intrinsic disorder prediction intrinsically disordered region protein conformation transcriptome RNA sequencing Microarray differentially regulated genes gene ontology analysis functional analysis intrinsically disordered structural disorder correlated mutations co-evolution evolutionary couplings residue co-variation interaction surface residue contact network dehydron homodimer hydrogen bond inter-subunit interaction ion pair mutual synergistic folding solvent-accessible surface area stabilization center MLL proteins MLL4 lncRNA HOTAIR MEG3 leukemia histone lysine methyltransferase RNA binding protein hydration wide-line 1H NMR secretion immune extracellular protein-protein interaction structural domain evolution transcription factors DNA-protein interactions Sox2 sequential DNA loading smFRET DNA conformational landscape sequential DNA bending transcription factor dosage oligomer N-terminal prion protein copper binding prion disease mutations Nuclear pore complex FG-Nups phosphorylation coarse-grained CABS model MC simulations statistical force fields protein structure intrinsically disordered proteins (IDPs) neurodegenerative diseases aggregation drugs drug discovery plant virus eIF4E VPg potyvirus molten globule fluorescence anisotropy protein hydrodynamics |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557509403321 |
Simon Istvan | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Plant Virus Emergence |
Autore | Goodin Michael |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
Descrizione fisica | 1 electronic resource (174 p.) |
Soggetto topico | Research & information: general |
Soggetto non controllato |
sugar beet
rhizomania RNAseq virus necrovirus helper virus Aphis gossypii Cucumis melo cucurbit viruses disease progress curve insect trapping logistic model Spearman correlation temporal dynamics Bunyavirale RNA virus emerging virus virus evolution plant virus cophylogeny hallmark genes common bean Phaseolus vulgaris cytorhabdovirus whitefly Bemisia tabaci vector virus transmission ToTV emerging disease prevalence whole-genome sequencing phylogeny tomato torrado virus sGFP plant pathology infectious clone plant-virus interaction pandemics epidemics global disease threat food insecurity crop losses crop failure indigenous viruses introduced crops new encounter spillover developing countries domestication centers sub-Saharan Africa Potyviruses whole genome sequencing epidemiology virus resistance virus host interactions plant viruses viral vectors plant diseases virus spread biopharming vaccines viruses Nicotiana benthamiana COVID-19 plant-based biologics production |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557563403321 |
Goodin Michael | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Plant Viruses: From Ecology to Control |
Autore | Castillo Jesús Navas |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
Descrizione fisica | 1 electronic resource (293 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences |
Soggetto non controllato |
whitefly
begomovirus Vta1 virus transmission coat proteins membrane association topology cilevirus movement protein p29 capsid protein barley yellow dwarf virus BYDV wheat barley yield loss vectors aphids persistent virus Amalgaviridae synergism antagonism vsiRNAs miRNAs mixed-infections Arabidopsis thaliana Cucumber mosaic virus genome-wide association studies plant-virus interaction seed transmission virulence callose coat protein plasmodesmata triple gene block viral suppressor virus movement virus replication complex TYLCD TYLCV tomato Solanum lycopersicum disease resistance plant breeding PAMP-triggered immunity effector-triggered immunity RNA silencing viral suppressors NIK1 PTI ETI geminiviruses host jumping viral evolution trade-off plant virus RNA virus potyvirus Plum pox virus VPg eIF4E high-throughput sequencing bioinformatics detection discovery MinION nanopore sequencing rolling circle amplification viral metagenomics CRESS DNA capulavirus homopolymer Begomovirus cucumber mechanical inoculation real-time PCR viral load QTLs resistance Geminiviridae sweepoviruses DNA satellites Deltasatellite helper virus range transreplication high-throughput sequencing (HTS) virus dsRNA total RNA OLV1 LRNV ToFBV ASGV host adaptation virus evolution |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Plant Viruses |
Record Nr. | UNINA-9910557421803321 |
Castillo Jesús Navas | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
The Application of Viruses to Biotechnology |
Autore | Varanda Carla |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
Descrizione fisica | 1 electronic resource (296 p.) |
Soggetto topico | Technology: general issues |
Soggetto non controllato |
Bacteriophage
Salmonella biocontrol comparative genomics phage diversity grapevine apple latent spherical virus vector virus-induced flowering reduced generation time breeding of grapevine virus elimination Newcastle disease virus reverse genetics vaccines infectious diseases cancer porcine epidemic diarrhea virus VLP chemokines pig vaccine SARS-CoV-2 COVID-19 phages CRISPR viruses prevention diagnosis treatment adeno-associated virus (AAV) vector jaagsiekte sheep retrovirus (JSRV) LTR enhancer transduction viral vaccines cancers COVID-19 vaccines self-replicating RNA vectors DNA-based vaccines RNA-based vaccines plant virus viroid viral vector virus-induced gene silencing (VIGS) CRISPR/Cas9 genome editing carotenoid biosynthesis circular RNA infectious bursal disease virus immunization recombinant Lactococcus lactis variant strain baculovirus insect cells bacmid Tn7 genome stability protein expression chikungunya virus VLPs bioreactor CRISPR/Cas systems viral vectors gene editing plant genome engineering viral resistance adeno-associated virus AAV cancer gene therapy prophage hydrothermal vent Hypnocyclicus thermotrophus lytic cassette Escherichia coli heterologous expression codon optimization codon harmonization expression vectors aspect ratio VNPs TMV PVX CPMV geminivirus theranostics CRISPR-cas9 clodronate macrophage gene therapy gene expression nanotechnology |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557363903321 |
Varanda Carla | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Virus-Like Particle Vaccines |
Autore | Bachmann Martin F |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (262 p.) |
Soggetto topico |
Humanities
Social interaction |
Soggetto non controllato |
virus-like particle
influenza A(H1N1)pdm09 vaccination pregnant women antibody titers norovirus VLP vaccine genotype pre-existing immunity cross-reactivity blocking antibodies original antigenic sin (OAS) HPVs vaccines virus-like particles (VLPs) minor capsid protein (L2) HCMV cytomegalovirus nanoparticle immune response Sudan virus mice horse purified IgG long-lived plasma cells antibodies multivalency virus-like particles antigenic analysis epitope characterization hepatitis E vaccine serological evaluation virion-like epitopes well-characterized vaccines hepatitis B virus surface (envelope) antigen sub-viral particle capsid antigen display platform viral quantification NTA flow virometry SRFM cryo-TEM SEM plant virus virus-like vaccine platform epitope antigen cat allergy Fel d 1 HypoCat™ IL-13 interleukin-13 Tfh cells cancer immunotherapy H7N9 pandemic influenza A avian flu IAV VLP vaccine |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557525903321 |
Bachmann Martin F | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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