Molecular Therapies for Inherited Retinal Diseases
| Molecular Therapies for Inherited Retinal Diseases |
| Autore | Collin Rob W.J |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (262 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
AAV
ABCA4 adeno-associated viral adeno-associated virus (AAV) allele-specific knockdown antisense oligonucleotides AON-mediated exon skipping apical polarity apoptosis ARPE-19 cells autophagy autosomal dominant bipolar cells CEP290 chaperones chaperonins choroideremia Cilia elongation clathrin-coated vesicles clinical trials clustered regularly interspaced short palindromic repeats (CRISPR) compound therapies cones crumbs complex cyclic GMP DNA therapies DNA-wrapped gold nanoparticles drug delivery systems dual AAV endosomal trafficking Enhanced S-Cone Syndrome (ESCS) fetal retina Flanders founder c.4723A > G56R gapmer antisense oligonucleotides gene augmentation gene therapy gold nanoparticles heat shock response homology-directed repair (HDR) induced pluripotent stem cell (iPSC) inherited retinal disease inherited retinal diseases iPSC-derived photoreceptor precursor cells IRD Leber congenital amaurosis Leber congenital amaurosis and allied retinal ciliopathies microRNA Müller glia n/a necrosis nonprofit NR2E3 PAR complex patient registry photoreceptors protein degradation protein folding protein trafficking putative dominant negative effect REP1 retina retinal degeneration retinal inherited disorders retinal organoids retinal pigment epithelium retinitis pigmentosa Retinitis Pigmentosa (RP) Retinitis Pigmentosa GTPase Regulator retinogenesis RNA therapies RNA therapy rods RPE65 splicing modulation spontaneous nonsense correction Stargardt disease T nonsense mutation therapy translational translational medicine treatment unfolded protein response Usher syndrome |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674051103321 |
Collin Rob W.J
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Lo trovi qui: Univ. Federico II | ||
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Optogenetic Tools in the Molecular Spotlight
| Optogenetic Tools in the Molecular Spotlight |
| Autore | John T. M. Kennis |
| Pubbl/distr/stampa | Frontiers Media SA, 2016 |
| Descrizione fisica | 1 online resource (179 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
computational modeling
Flavins Opsins optogenetics Photochemistry and photophysics photoreceptors Phytochrome Protein Engineering spectroscopy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910220046703321 |
John T. M. Kennis
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| Frontiers Media SA, 2016 | ||
| Lo trovi qui: Univ. Federico II | ||
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Plant Development and Organogenesis: From Basic Principles to Applied Research
| Plant Development and Organogenesis: From Basic Principles to Applied Research |
| Autore | Frugis Giovanna |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (246 p.) |
| Soggetto non controllato |
age
Agrobacterium rhizogenes ambient temperature Arabidopsis Arabidopsis thaliana Asteraceae auxin auxin conjugation auxin minimum boundaries Brassicaceae cell wall CLE CLV crop productivity cytokinin cytoskeleton Development differentiation embryogenesis flowering time genes of reproductive isolation genetic improvement genetic transformation gibberellins grass GRETCHEN HAGEN 3 (GH3) IAA-amido synthase group II ground tissue hairy roots HD-Zip transcription factors hydrogen peroxide KNOX transcription factors lateral root cap light environment ligule linkage map locule meristem meristem formation molecular marker molecular regulation morphogenesis morphogenic organogenesis Organogenesis photoperiod photoreceptors phytohormones plant breeding plant cell and tissue culture plant development plant development and organogenesis Plant in vitro cultures proline biosynthesis protoxylem proximodistal patterning radial patterning recalcitrant species reduced height regulatory networks Rht18 rol genes RolD root root apical meristem root development root plasticity SAM semi-dwarf shoot meristem signaling somatic cell selection stem apical meristem stem cells transformation translational research tree phase change Vasculature vernalization wheat wheat-rye hybrids wounding WUS |
| ISBN | 3-03928-127-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Plant Development and Organogenesis |
| Record Nr. | UNINA-9910372782903321 |
Frugis Giovanna
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Lo trovi qui: Univ. Federico II | ||
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The Retina in Health and Disease
| The Retina in Health and Disease |
| Autore | Ptito Maurice |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (465 p.) |
| Soggetto topico |
Medicine and Nursing
Neurosciences |
| Soggetto non controllato |
3,5-DHBA
Ac2-26 African-American age-related macular degeneration AII amacrine cell altricial bird species Alzheimer's disease AMD amyloid angiogenesis angiography antioxidants apoptosis arterioles astrocytes ATP atypical cannabinoid receptors autophagy axon betulinic acid bioenergetics biomarker black catalase CD4+CD25+ cellular senescence Charles Bonnet syndrome clinical trials cognitive decline complement cascade complication development diabetes diabetes mellitus diabetic retinopathy dLGN Drp1 early detection eccentricity EEG electron microscopy electroretinography endoplasmic reticulum epidermal growth factor exendin-4 experimental models eye eye inflammation fingolimod FPR receptor functional analysis gap junction germ-free mice GFAP glucagon-like peptide-1 GPR81 growth cone GRP78 gut microbiome gut-retina axis HCAR1 HDAC high-fat diet histone deacetylase hyperglycemia hypoxia immunodeficient RCS rat immunohistochemistry inflammation inflammatory mediators iPSC iPSC-RPE ischemia-reperfusion injury kallikrein-kinin system kinin receptors lactate LED screen light damage lipopolysaccharide macroglia mesenchymal stem cells metabolism microglia microglia morphotype microvascular microvascular complications and dysfunction mitochondria monkeys motor protein Müller cells multiple sclerosis myosin 1C n/a natural bioactive extracts neurod neurodegeneration neuroprotection neurovascular unit Notch ON/OFF asymmetry optic nerve crush optic neuritis optical coherence tomography optical filter osteopontin outer segments oxidative stress parvalbumin photoreceptor photoreceptors precocial bird species progenitor cell programmed cell death Prox1 reactive oxygen species regeneration remodeling respiration resting state retina retinal degeneration retinal degenerative diseases retinal detachment retinal fluorescence imaging retinal ganglion cells retinal glial cell retinal inflammation retinal light injury retinal microglia retinal pigment epithelium retinal protection retinal transplantation retinal vessels retinogenesis retinopathy rhodopsin RNA sequencing senescence-associated galactosidase activity signal transducer and activator of transcription 3 spinal cord injury stem cell therapy stress response systemic disease trichostatin A (TSA) typical cannabinoid receptors ultrathin parylene unfolded protein response vascular endothelial growth factor (VEGF) vascularization visual function visual hallucination visual system zebrafish |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557336603321 |
Ptito Maurice
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Lo trovi qui: Univ. Federico II | ||
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