Autore	Pörtner Ralf
Descrizione fisica	1 online resource (226 p.)
Soggetto topico	History of engineering and technology Technology: general issues
Soggetto non controllato	Adeno-associated virus Bayes optimization biopharmaceutical manufacturing bioprocess bioreactor bioreactor characterization biosensor biotherapeutics production cell culture cell culture model Chinese hamster ovary cells CHO DP-12 clonal cell population computational fluid dynamics continuous critical shear stress cryopreservation diabetes Escherichia coli Gaussian processes gene therapy hybrid modeling hydrodynamic gradients hydrodynamic stress inoculum train Kolmogorov length scale machine learning microcarriers model-assisted DoE monitoring monoclonal antibodies multi-objective n/a N−1 perfusion operational space Pareto optimization PAT PEI phenotypic diversity process analytical technology (PAT) process development process intensification quality by design quality by design (QbD) seed train sensors shear stress-guided production smart biomanufacturing soft-sensor spectroscopy spheroid strength surface plasmon resonance (SPR) transfection transient expression uncertainty-based upstream bioprocessing upstream processing vaccines production β-cells
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Record Nr.	UNINA-9910595072803321

Autore	Wagner Günter P.
Edizione	[Course Book]
Pubbl/distr/stampa	Princeton, New Jersey : , : Princeton University Press, , 2014
Descrizione fisica	1 online resource (495 p.)
Disciplina	571.8/5
Soggetto topico	Developmental genetics Evolution (Biology) Genetic regulation
Soggetto non controllato	adaptation amniotes angiosperms autopodium biological diversity body parts body plans breasts canalization cell fate cell type identity cell types cell typogenesis cells character identity network character identity character origination character states characters cis-regulatory elements class common ancestor common ancestry cryptic genetic variation development developmental biology developmental evolution developmental genetics developmental mechanisms developmental pathways developmental types developmental variation devo-evo research digit identity digit loss digits embryonic stem cells evolution evolutionary biology evolutionary developmental biology evolutionary novelties feathers fins finЬimb transition flower development flower organ identity flower organs flowers functional specialization functionalism gene duplication gene expression gene regulatory networks genes genetics hair hierarchical homology homeotic genes homologous genes homologs homology individuals innovation limbs metaphysics modularity molecular genetics molecular structuralism morphological characters morphological variation natural kinds natural selection novel characters paired fins pentadactyl limb perianth phenotypic diversity phenotypic evolution philosophy population biology positional information robustness scales science serial homology signaling centers skin appendages skin derivatives skin structuralism tetrapod hand tetrapod limbs transcription factor proteins transcription factors transcriptional regulation transposable elements typology variational structuralism vertebrates
ISBN	1-4008-5146-7
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	Front matter -- Contents -- Preface -- Introduction: What This Book Aims to Do and What It Is Not -- Part I. Concepts and Mechanisms -- Part II. Paradigms and Research Programs -- References -- Index
Record Nr.	UNINA-9910787878003321