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Big Data, Pharmacogenomics and Real-World Research in Pharmacology
| Big Data, Pharmacogenomics and Real-World Research in Pharmacology |
| Autore | Cheng-Chung Wei James |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (165 p.) |
| Soggetto topico |
Science: general issues
Pharmacology |
| Soggetto non controllato |
big data
database real-world study pharmacogenomics cohort |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557212603321 |
Cheng-Chung Wei James
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biomarkers for Diagnosis, Complications and Therapy Effects in Civilization Diseases Management
| Biomarkers for Diagnosis, Complications and Therapy Effects in Civilization Diseases Management |
| Autore | Komosinska-Vassev Katarzyna |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (208 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
pharmacogenomics
NGS variants personalized medicine FSHR personalized drug therapy hedgehog-interacting protein impaired fasting glucose impaired glucose tolerance newly diagnosed diabetes normal glucose tolerance inflammatory bowel disease ulcerative colitis Crohn’s disease extracellular matrix components hyaluronan inflammatory bowel diseases (IBD) Crohn’s disease (CD) ulcerative colitis (UC) sulfated glycosaminoglycans (sGAG) hyaluronan (HA) soluble part of syndecan-1 (sCD138) microRNA cardiovascular disease diabetes mortality antiplatelet therapy platelet reactivity Let-7e miR-126 miR-223 miR-125a-3p CCL11 CCL24 CCL26 CCR3 CRC adiponectin adipokines rheumatology obesity overweight case control study rheumatoid arthritis TNF-α inhibitors bone turnover markers PINP PICP NTX-I CTX-I RANKL/OPG ovarian cancer interleukin 21 interleukin 22 lymphocytes macrophages dendritic cells innate lymphoid cells breast cancer extracellular matrix proteins tumorigenesis tumor microenvironment |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566458203321 |
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Komosinska-Vassev Katarzyna
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Clinical Utility of Applying PGx and Deprescribing-Based Decision Support in Polypharmacy : Future Perspectives
| Clinical Utility of Applying PGx and Deprescribing-Based Decision Support in Polypharmacy : Future Perspectives |
| Autore | Vermehren Charlotte |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (224 p.) |
| Soggetto topico |
Medicine
Pharmaceutical industries |
| Soggetto non controllato |
acute kidney injury
early biomarker plasma neutrophil gelatinase-associated lipocalin soluble urokinase plasminogen activator receptor medication optimization older patients emergency department multimorbidity polypharmacy potentially inappropriate medication use older adults prevalence determinants chronic outpatient 2019 Beers criteria Ethiopia pharmacogenomics persons with diabetes drug–drug interactions drug–gene interactions cytochrome P450 SLCO1B1 drug interaction checkers adverse drug reactions pharmacogenetics personalized medicine phenprocoumon DOACs bleeding thromboembolism HLA drug hypersensitivity abacavir allopurinol flucloxacillin antiepileptic drugs cost-effectiveness shared medication record medication reconciliation drug information service hospital pharmacy service electronic prescribing electronic medical record clinical pharmacist CYP2D6 CYP2D7P CYP2D8P copy number variation CNV genotyping 5’nuclease assay HRM high resolution melting drug metabolization extracellular vesicles exosomes microvesicles pharmacogene expression medication review deprescriptions quality of life aged aged, 80 and over nursing homes deprescribing medication-based risk score health outcomes cytochromes CYP1A2 adverse drug reaction antipsychotics olanzapine clozapine loxapine children youth digital decision-support health services research general practice process evaluation antidepressants utility population-based appropriateness medication adherence digital health |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Clinical Utility of Applying PGx and Deprescribing-Based Decision Support in Polypharmacy |
| Record Nr. | UNINA-9910595072903321 |
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Vermehren Charlotte
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Identification and Characterization of Genetic Components in Autism Spectrum Disorders 2020
| Identification and Characterization of Genetic Components in Autism Spectrum Disorders 2020 |
| Autore | Butler Merlin G |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (204 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Genetics (non-medical) |
| Soggetto non controllato |
autism
ASD genetics heterogeneity syndromes assessment medications treatment causes autism spectrum disorders (ASDs) proteomics metabolomics interactomics disease biomarkers clinical decision support systems (CDSSs) phenotypic subgroups stratified by ASD severity simplex families DNA methylation subgroup-associated genes and biological functions Broader Autism Phenotype genetic autism spectrum disorder multiplex family genetic factors epigenetic factors environmental factors pervasive developmental disorder post-synaptic density CNV SNP gene fusion CACNA1C CaV1.2 short QT syndrome dental enamel defect bioinformatics human genetics pharmacogenomics 15q11.2 BP1-BP2 deletion Burnside-Butler syndrome clinical findings cognition neuropsychiatric behavior development genomic characterization exome sequencing protein–protein interaction 22q13.3 duplication auditory steady-state response ASSR SHANK3 biomarker auditory event-related potential ERP autism spectrum disorders intellectual disabilities |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566463603321 |
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Butler Merlin G
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pharmacogenetics to Avoid Adverse Drug Reactions
| Pharmacogenetics to Avoid Adverse Drug Reactions |
| Autore | López-Fernández Luis A |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (220 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
5-fluorouracil
capecitabine fluoropyrimidine thymidylate synthase thymidylate synthase enhancer region upstream stimulatory factor 1 adverse drug reactions pharmacogenomics epistasis random forest statin cardiovascular disease colorectal cancer personalised medicine toxicity (es)citalopram drug-gene-interaction drug-drug-interaction drug-drug-gene-interaction the PharmLines initiative antipsychotic agents pharmacogenetics cytochrome P-450 enzyme system psychotic disorders precision medicine direct oral anticoagulants clinical implementation atorvastatin SLCO1B1 HLA cutaneous adverse drug reaction SCAR genetic polymorphism antiepileptics CYP450 enzymes platelet reactivity single-nucleotide variants acute coronary syndrome clopidogrel genotype allele polymorphism HLA B CYP2C9*3 cutaneous adverse drug reactions (CADRs) anti-epileptic drugs (AEDS) phenytoin (PHT) genetic risk factors South India India cardiology adverse events guidelines |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557610103321 |
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López-Fernández Luis A
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pharmacogenomics : From Basic Research to Clinical Implementation
| Pharmacogenomics : From Basic Research to Clinical Implementation |
| Autore | Scheinfeldt Laura B |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (162 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
pharmacogenomics
return of results genetic counseling qualitative pharmacogenetics implementation pharmacogenetics service screening pre-emptive personalized medicine precision medicine community pharmacy pharmacogenomic testing genetic privacy pharmaco-economics polymorphisms pharmacogenes pharmacogenomic machine learning adaptation human evolution US Food and Drug Administration clinical actionability clinical translation chronic kidney disease CYP3A5 polymorphism progression pharmacogenomics (PGx) pediatrics best practice alerts (BPAs) electronic health records (EHR) genomic indicators clinical decision support (CDS) phenotype genotype polypharmacy chronic disease medication management electronic medical record artificial intelligence |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Pharmacogenomics |
| Record Nr. | UNINA-9910566459103321 |
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Scheinfeldt Laura B
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pharmacogenomics and Personalized Medicine
| Pharmacogenomics and Personalized Medicine |
| Autore | Cecchin Erika |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (208 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
CYP2C9
VKORC1 warfarin warfarin initiation phase of therapy INR pharmacogenetics study pharmacogenomics pharmacogenetics genotype phenotype alleles precision medicine pharmacotranscriptomics high-throughput analysis childhood acute lymphoblastic leukemia clopidogrel acenocoumarol CDSS implementation azathioprine inflammatory bowel disease glutathione-S transferase pharmacokinetics nucleoside analogs microRNAs gene expression drug resistance AML cisplatin nephrotoxicity kidney injury genetic polymorphisms pre-emptive panel breast cancer subtype miRNA pathway crosstalk network precision drugs ovarian cancer platinum resistance focal copy number alterations whole exome sequencing personalized medicine human genetics pharmacology |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557287703321 |
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Cecchin Erika
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pharmacy Practice and Administration
| Pharmacy Practice and Administration |
| Autore | Adunlin Georges |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (260 p.) |
| Soggetto topico |
Medicine
Pharmaceutical industries |
| Soggetto non controllato |
older adults
polypharmacy internal medicine ward community pharmacy drug disposal unused medication environment awareness practice ambulatory care facilities health workforce pharmacists Taiwan Commonwealth Partnerships for Antimicrobial Stewardship (CwPAMS) National Health Service (NHS) Chief Pharmaceutical Officer’s Global Health Fellowship CPhOGH Fellows CwPAMS pharmacy fellowship health partnerships antimicrobial resistance (AMR) global health leadership non-prescription medicines emergency contraception community pharmacies information gathering availability pricing mystery calls ulipristal acetate levonorgestrel Germany e-prescription prescription writing Jazan Saudi Arabia prescription errors medicine consumption defined daily dose adolescents and young adults cancer patients fragility pain MUR medication review barriers pharmacist pregabalin abuse community pharmacists reproductive health contraception emergency contraceptives patient education biosensing technology digital medicine system medication adherence medication event monitoring system nonadherence prescription opioids mortality standardized mortality ratio underlying cause of death prescriptions community pharmacy services emergency prescribing pharmacy practice pharmacy law and regulation COVID-19 additional monitoring black triangle adverse event reporting pharmacovigilance intervention outcomes systematic review pharmacy education decision to study in pharmacy selecting pharmacy as a first choice pharmacogenomics learning activity asynchronous learning virtual learning student survey Program of All-Inclusive Care for the Elderly adverse drug events medication-related problems drug-related problems medication safety Medicare Medicaid financial management pharmacy management business entrepreneurship pharmacy students perception attitudes ability interprofessional simulation acute care nursing students standardized patients high fidelity SPICE-R2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585940103321 |
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Adunlin Georges
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Precision Medicine : Applied Concepts of Pharmacogenomics in Patients with Various Diseases and Polypharmacy
| Precision Medicine : Applied Concepts of Pharmacogenomics in Patients with Various Diseases and Polypharmacy |
| Autore | Turgeon Jacques |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (170 p.) |
| Soggetto topico |
Medicine
Clinical & internal medicine |
| Soggetto non controllato |
fibromyalgia (FM)
myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) microRNA miRNome pharmacogenomics pharmacoepigenomics SM2miR Pharmaco-miR repoDB ME/CFS Common Data Elements (CDEs) dihydropyrimidine dehydrogenase DPYD 5-fluorouracil fluoropyrimidine therapeutic drug monitoring orthotopic liver transplant busulfan glutathione S-transferase genetic polymorphism limited sampling strategy pharmacokinetics clinical pharmacogenetics pharmacogenetic testing adverse drug reactions genotype phenotype pharmacogene barriers to pharmacogenetics implementation Sub-Saharan Africa chronic low back pain (cLBP) genetics personalized treatment polymorphism CYP450 tacrolimus CYP3A5 liver transplant pharmacogenomic minority data collection drug biomarker pharmacogenetics pharmacogenetic test personalized medicine gene expression infliximab adalimumab ulcerative colitis Crohn disease inflammatory bowel disease |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Precision Medicine |
| Record Nr. | UNINA-9910585940803321 |
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Turgeon Jacques
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Rheumatoid Arthritis Therapy Reappraisal : Strategies, Opportunities and Challenges
| Rheumatoid Arthritis Therapy Reappraisal : Strategies, Opportunities and Challenges |
| Autore | Müller Rüdiger |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (260 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
rheumatoid arthritis
sleep sleep disorders pain osteoporosis fracture fracture risk assessment tool treat-to-target certolizumab pegol csDMARDs glucocorticoids intra-articular injections DAS 28 ACR response HAQ-DI TNFα golimumab efficacy tolerability immunogenicity methotrexate posology titration oral route subcutaneous route bioavailability effectiveness periodontitis periodontal disease anti-citrullinated protein autoantibodies rheumatoid factor smoking medication Porphyromonas gingivalis Rheumatoid arthritis matrix metalloproteinase 3 infliximab pharmacogenomics anti-TNF personalized medicine baricitinib disease-modifying antirheumatic drugs pain perception outcomes research patient perspective Rheumatoid Arthritis therapy DMARD MTX Tumor Necrosis Factor-Alpha Inhibitors ankylosing spondylitis biosimilar switching synovial fibroblasts cytokine osteoclast herbal medicine methylation next-generation sequencing recovery of function fatigue productivity tofacitinib oral Th1.17 IL-17A IFN-γ, CD73 adenosine psoriatic arthritis regulation pseudoerosions hand foot ultrasonography radiography computed tomography magnetic resonance imaging |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Rheumatoid Arthritis Therapy Reappraisal |
| Record Nr. | UNINA-9910557286503321 |
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Müller Rüdiger
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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