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Cancer Metabolomics 2018 / Paula Guedes De Pinho, Márcia Carvalho, Joana Pinto
| Cancer Metabolomics 2018 / Paula Guedes De Pinho, Márcia Carvalho, Joana Pinto |
| Autore | De Pinho Paula Guedes |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (184 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
cell transporters
pharmacodynamics cell growth in vitro study metabolomic signatures endometabolome lung cancer metabolomics chemometric methods bladder cancer mTOR metabolite profiling metabolic pathways hepatocellular carcinoma glutamate senescence MCF7 breath analysis bio actives biomarker gas chromatography–mass spectrometry (GC–MS) GC-MS lung omics nutraceuticals glutaminase metabolism acylcarnitines Erwinaze Kidrolase glutathione targeted metabolomics apoptosis SLC1A5 essential amino acids cancer progression ASCT2 HR MAS alanine analytical platforms volatile organic compound glutaminolysis isotope tracing analysis asparaginase vitamin E breast cancer prognosis early diagnosis tocotrienols NMR prostate cancer in vitro cancer MDA-MB-231 |
| ISBN |
9783039213467
3039213466 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367563603321 |
De Pinho Paula Guedes
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cholinesterase Research
| Cholinesterase Research |
| Autore | Korabecny Jan |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (223 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
acetylcholinesterase
acetylcholinesterase inhibitor acetylcholinesterase inhibitors alkaloids Alzheimer disease Alzheimer's disease Amaryllidaceae antioxidants behavior blood-brain barrier crossing bone healing butyrylcholinesterase butyrylcholinesterase inhibitors carltonine A-C catalysis cholinesterase dementia docking docking studies donepezil fluorene hemostasis hydrolysis in silico in vitro inhibition MD simulations molecular dynamics molecular modeling molecular modelling molecular recognition multi-target directed ligands N-methyl-d-aspartate receptor n/a Narcissus pseudonarcissus cv. Carlton neutron scattering nutraceuticals organophosphates organophosphorus organophosphorus nerve agents osmotic stress osseointegration oxime pharmacodynamics phytochemicals reactivation reactivation process reactivators slow-binding inhibition transition state analog ventilation zebrafish |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557764703321 |
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Korabecny Jan
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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From a Molecule to a Drug: Chemical Features Enhancing Pharmacological Potential
| From a Molecule to a Drug: Chemical Features Enhancing Pharmacological Potential |
| Autore | Ribaudo Giovanni |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (234 p.) |
| Soggetto topico |
Medicine and Nursing
Pharmacology |
| Soggetto non controllato |
3-chymotrypsin-like protease
affinity chromatography alginate anti-ACE anti-DPP-IV anti-inflammatory drugs antioxidant activity benzoic acid derivatives big data binding free energy Box-Behken breast milk cannabinoid chemoinformatics chromatographic descriptors cisplatin clopidogrel coronavirus SARS-CoV-2 COVID-19 cyclooxygenase cytoprotection DFT calculations drug compounding drug discovery E-selectin Eucheuma gelatinae extraction fucoidan gallic acid gastrointestinal digestion high performance liquid chromatography ICAM-1 imine-enamine in silico L-selectin lithium therapy M/P ratio MCP-1 methadone hydrochloride microbiology molecular descriptors molecular docking molecular dynamics molecular dynamics simulations monocyte migration multitarget drug n/a nephrotoxicity neurocytology neuropathic pain neuroprotection NMR study one-pot oxone pain management paramyosin peroxymonosulfate pharmaceutical solutions pharmacodynamics pharmacokinetics physic-chemistry precision medicine protein binding pyrimidonic pharmaceuticals QSAR quercetin quercetin 3-O-glucuronide reaction mechanism reactivity parameters rheology SARS-CoV-2 seafood selenium selenoxide elimination sodium halide stability study statistical modeling target fishing thienopyridine THP-1 macrophage toxicology β-carrageenan |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | From a Molecule to a Drug |
| Record Nr. | UNINA-9910585940503321 |
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Ribaudo Giovanni
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Micro/Nanofluidic and Lab-on-a-Chip Devices for Biomedical Applications
| Micro/Nanofluidic and Lab-on-a-Chip Devices for Biomedical Applications |
| Autore | Carvalho Violeta |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (232 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
protein biomarker
microarray microfluidic cassette multiplex measurement immunoassay point-of-care testing microfluidic device small intestine ex vivo histology embedded resin sectioning peptide biosensor lab-on-a-chip label-free detection peptide aptamers protein biomarkers microfluidic biochip troponin T computational simulations drug discovery organ-on-a-chip microfluidic devices preclinical models numerical simulations automation non-enzymatic DNA amplification L-DNA microfluidic fluorescence paper microfluidics sweat sensing hydrogels lactate osmotic pumping evaporation capillary wicking biochemical assay microfluidics cell trap RBC evolutionary algorithm generative design artificial intelligence organ-on-chip liver-on-chip liver disease multi-level microfluidic device live cell imaging long-term microscopy imaging focus drifting immersion oil viscosity bacterial population dynamics single-cell studies E. coli mother machine computational fluid dynamics cancer-on-chip xenograft colorectal cancer pharmacodynamics pharmacokinetics drug efficacy oxaliplatin microfabrication microphysiological system biophysical stimuli biochemical stimuli in vitro cell culture cortical neurons hippocampal neurons electrical stimulation Micro-Electrode Arrays engineered neuronal networks polydimethylsiloxane microchannels in vivo micro bioreactor additive manufacturing poly-(ethylene glycol)-diacrylate biocompatibility COVID-19 diagnosis image analysis PCR SARS-CoV-2 |
| ISBN | 3-0365-6099-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639996703321 |
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Carvalho Violeta
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tuberculosis Drug Discovery and Development 2019
| Tuberculosis Drug Discovery and Development 2019 |
| Autore | Riccardi Giovanna |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (296 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
anti-TB drug pipeline
anti-virulence compounds antibiotic antimicrobial drug resistance (AMR) antimycobacterial antituberculosis agents artificial pneumothorax BCG bedaquiline biomarkers Carlo Forlanini caseum cell envelope clinical studies clinical trial CTVD delpazolid discovery DNA gyrase dormancy DprE1 inhibitor drug combination drug development drug discovery drug resistance drug-drug interactions EDCTP electron transport chain energy metabolism genomics granulomas host-directed therapy IAVI in vitro in vivo isoniazid lead generation lipidomics macozinone mechanism of action mechanisms of resistance metabolomics MID3 mode of action multi-drug resistance mutations mycobacteria mycobacterium Mycobacterium tuberculosis n/a oxidative phosphorylation pharmacodynamics pharmacokinetics phenotypic screening PknB PknG post-treatment sequelae privileged targets promiscuous targets proteomics pulmonary rehabilitation Q203 rifampin structure-based drug design surgery target target identification target-based drug design target-based screening TB TBVI toxicity transcriptomics tuberculosis tuberculosis treatment tuberculosis vaccines |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557627203321 |
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Riccardi Giovanna
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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