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ABC Transporters in Human Diseases
| ABC Transporters in Human Diseases |
| Autore | Falguières Thomas |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (494 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
ABC transporters
drug action regulatory extension regulatory insertion mechanism of action MRP1 MRP4 breast cancer proliferation migration invasion cAMP ABCG2 ABCB1 blood-brain barrier PET Alzheimer's disease beta-amyloid tariquidar erlotinib ABCG5 ABCG8 ATP-binding cassette transporter cholesterol polar relay sitosterolemia 5' untranslated region cis-acting elements ABCA subfamily bioinformatics ABC transporter therapy response disease-free survival next-generation sequencing competitive allele-specific PCR P-glycoprotein amyloid-beta neuron SK-N-SH gene therapy AAV PFIC BSEP ABCB11 bile salts intrahepatic cholestasis chaperones PFIC2 BRIC ATP-binding cassette transporter A1 (ABCA1) cholesterol homeostasis reverse cholesterol transport HDL-C dyslipidemia type 2 diabetes microparticles ABCG2 genotype clinico-genetic analysis ethnic specificity genetic variations precision medicine rare variant Roma serum uric acid SUA-lowering therapy urate transporter bile secretion ABCB4 ABCC2 ABCG5/G8 molecular partners phytosterol xenosterol atherosclerosis gall stone ABC transporter ABC (ATP-binding cassette) transporters multidrug resistance transport trafficking urate mutations polymorphisms ABCC6 TNAP NT5E Pseudoxanthoma elasticum (PXE) cancer membrane protein functional divergence calcification pseudoxanthoma elasticum generalized arterial calcification of infancy pyrophosphate therapies ABCA7 phagocytosis Aβ peptides yeast multidrug transporter anticancer antifungal resistance mechanism peroxisome adrenoleukodystrophy fatty acids gout early-onset gout hyperuricemia uric acid BCRP single nucleotide polymorphism SNP homology modeling substrate-binding site cellular ATP efflux mutagenesis intracellular traffic MDR3 phosphatidylcholine RAB GTPase taxol drug transport |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674029103321 |
Falguières Thomas
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nitric Oxide Signaling in Plants
| Nitric Oxide Signaling in Plants |
| Autore | Hancock John |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (170 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
catalase
monodehydroascorbate reductase tyrosine nitration nitric oxide peroxisome reactive oxygen species S-nitrosation superoxide dismutase antioxidants hydrogen gas hydrogen peroxide hydrogen sulfide S-nitrosothiols S-nitrosoglutathione reductase S-(hydroxymethyl)glutathione nitrate reductase NOFNiR nitrogen metabolism NIA1 NIA2 nitrite nitrate methyl viologen benzyl viologen NO analyzer molybdenum cofactor Arabidopsis thaliana nitro-fatty acids nitroalkenes nitroalkylation electrophile nucleophile signaling mechanism post-translational modification reactive lipid species nitro-lipid-protein adducts Trebouxia microalgae lipid peroxidation diaphorase activity lichens nitric oxide synthase nitrogen dioxide plant growth cell enlargement cell proliferation early flowering PsbO nitric oxide homeostasis cue1/nox1 reactive nitrogen species germination root development stress responses sugar metabolism nitration S-nitrosylation SNO-reductase thiol modification |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557117803321 |
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Hancock John
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Origin and spatiotemporal dynamics of the peroxisomal endomembrane system
| Origin and spatiotemporal dynamics of the peroxisomal endomembrane system |
| Autore | Richard A. Rachubinski |
| Pubbl/distr/stampa | Frontiers Media SA, 2015 |
| Descrizione fisica | 1 electronic resource (148 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
peroxisomal endomembrane system
development Reactive Oxygen Species Aging peroxisome Lipid Metabolism Endoplasmic Reticulum peroxisome biogenesis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910136390303321 |
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Richard A. Rachubinski
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| Frontiers Media SA, 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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PPARs as Key Mediators of Metabolic and Inflammatory Regulation
| PPARs as Key Mediators of Metabolic and Inflammatory Regulation |
| Autore | Vázquez-Carrera Manuel |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (456 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Biochemistry |
| Soggetto non controllato |
nuclear receptor
gene transcription inflammation molecular docking PPARβ/δ lung pulmonary artery GW0742 GSK3787 docking lipopolysaccharide (LPS) PPARγ ligand coumarin fluorescent ligand screening crystal structure PPAR atopic dermatitis psoriasis metabolic reprograming glucose fatty acids mycobacteria M. tuberculosis M. leprae PPARs lipid droplets metabolic alterations hepatic damage nuclear factors pharmacological targets AMPK GDF15 insulin resistance type 2 diabetes mellitus peroxisome proliferator-activated receptor gamma (PPARγ) real-time PCR ELISA immunohistochemistry signaling pathway PPAR gamma brain neural stem cells infection neuroinflammation HIV Zika cytomegalovirus neurogenesis microglia liver damage toll-like receptor 4 P2Y2 receptor metabolic syndrome resveratrol quercetin PPARα peroxisome β-oxidation PPRE ligand coregulator micronutrients PPARα knockout adipose tissue browning lipid metabolism depression PPARg neuropathology corticotropin releasing hormone norepinephrine subgenual prefrontal cortex amygdala nucleus accumbens common carotid artery occlusion electroretinography fibroblast growth factor 21 pemafibrate peroxisome proliferator-activated receptor alpha retinal ischemia skeletal muscle substrate metabolism nonalcoholic fatty liver disease (NAFLD) sex dimorphism lipidomics hepatic sex-biased gene expression PPARγ pulmonary arterial hypertension TGFβ vascular injury proliferation kidney fibrosis pattern-recognition receptors phagocytosis nitric oxide synthase fenofibrate oleoylethanolamide palmitoylethanolamide cancer immunity obesity diabetes miRNA DNA methylation histone modification peroxisome-proliferator-activated receptor fatty acid oxidation doping control regulatory T cells exercise nuclear receptors nutrigenomics energy homeostasis dairy animals non-alcoholic fatty liver disease (NAFLD) non-alcoholic steatohepatitis (NASH) peroxisome proliferator-activated receptors (PPAR) bezafibrate fenofibric acid peroxisome proliferator-activated receptor dual/pan agonist X-ray crystallography |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576873703321 |
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Vázquez-Carrera Manuel
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Zika Virus and Host Interactions
| Zika Virus and Host Interactions |
| Autore | Hobman Tom |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (256 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Zika virus
peroxisomes innate immune response interferon astrocytes fetal brain zika virus flaviviruses T cells host-pathogen interactions flavivirus tight junctions claudins ZO-1 blood-placental barrier placenta apoptosis viral replication Bcl-2 protein family ZIKV virus host interactions pathogenesis MR766 guinea pig subcutaneous vaginal sexual transmission virus transmission envelope protein glycosylation fusion loop viral fusion cell entry NS5 protein nuclear localization inflammation innate immunity extracellular vesicles cellular communication C6/36 cells human monocytes endothelial vascular cells protein–protein interaction non-structural viral proteins network JAK/STAT cytokine West Nile virus HSP90 NS5 virus–host interactions anti-viral signaling immune response inflammatory mediator Sertoli cells Leydig cells ZIKA virus arboviruses infertility IFN RIG-I MDA5 IFNAR1 zika host cell death peroxisome mosquito tight junction |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557297503321 |
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Hobman Tom
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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