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Drug Delivery Technology Development in Canada
| Drug Delivery Technology Development in Canada |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (352 p.) |
| Disciplina | 615.1/900971 |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
3D spheroid
adenanthin amphotericin B antibodies bacteriophage bioaccessibility biodistribution biological barriers biologicals blood-brain barrier blood-brain barrier (BBB) Canada cancer canola oil deodorizer distillate cationic gemini surfactant child friendly formulation chronotherapy circadian clock cisplatin clinical trials co-delivery combination therapy controlled drug delivery developing world dissolution DOX-Vit D doxorubicin drug delivery drug delivery systems drug development drug discovery drug-resistant melanoma EGFR-targeted therapy emulsion encapsulation flavonoids formulation and dosage form development fungal infections gambogic acid gastrointestinal simulator GE11 peptide HAV6 cadherin peptide head and neck squamous cell carcinoma HIF-1 hypoxia-induced chemoresistance inclusion complex innovation intra-arterial chemotherapy lipid nanoparticles liposome liposomes loading gradients magnetic fields magnetic resonance imaging (MRI) malignant gliomas medical devices medulloblastoma mefloquine melphalan Metaplex MG63 model orange juice mouse models nanoparticles nifedipine oral oral delivery oral formulation parasitic infections permeation enhancers phage display pharmaceutics pharmacokinetics pharmacological Inhibitors of HIF-1 and STAT3 phospholipid complex photostabilizers phytosterols plant polymeric micelle precision medicine primary central nervous system lymphomas quercetin radiation radiolabeling remote loading ROESY NMR spectroscopy rosmarinic acid route of administration skin small molecules STAT3 staurosporine sustained delivery targeted therapies throughput TNO gastrointestinal model tocopherols topical formulation transdermal drug delivery transient modulation translational research triggered drug release ultrasound virus Vitamin D water miscible solvents |
| ISBN | 3-03928-005-8 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367736503321 |
| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Regional Intestinal Drug Absorption : Biopharmaceutics and Drug Formulation
| Regional Intestinal Drug Absorption : Biopharmaceutics and Drug Formulation |
| Autore | Gonzalez-Alvarez Maria Isabel |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (238 p.) |
| Soggetto topico |
Manufacturing industries
Medicine and Nursing |
| Soggetto non controllato |
absorption-modifying excipients
BCS class IV drugs BCS drugs bioequivalence biomimetic membrane biopharmaceutics biopharmaceutics classification system Biopharmaceutics Classification System clinical studies colon absorption combined zero- and first-order absorption controlled release drug product DDI disintegration dissolution dissolution test drug absorption drug permeability drug solubility drug solubility/dissolution drug-drug interactions energy intake enteric-coated first-order absorption first-pass effect Franz cell Franz-PAMPA furosemide gastrointestinal gastrointestinal hormone GastroPlus hierarchical support vector regression (HSVR) human colon carcinoma cell layer (Caco-2) ibuprofen ICH in silico modeling in situ perfusion in vitro in vitro in vivo extrapolations intestinal absorption intestinal perfusion intestinal permeability IVIVE location-dependent absorption manometry mechanistic modeling microdevices mucoadhesion nutrient absorption nutrient digestion obesity oral absorption oral drug delivery oral peptide delivery passive drug transport PBBM PBPK permeation enhancers pharmaceutical development pharmacokinetics Phoenix WinNonlin physiologically-based pharmacokinetic (PBPK) modeling postprandial glycaemia pravastatin quality control region of the gut regional intestinal permeability regional/segmental-dependent permeability and absorption route-dependent intestinal metabolism segmental-dependent intestinal permeability segregated flow intestinal model (SFM) shape traditional model (TM) transit compartment absorption model type 2 diabetes zero-order absorption |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Regional Intestinal Drug Absorption |
| Record Nr. | UNINA-9910566462603321 |
Gonzalez-Alvarez Maria Isabel
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Transmucosal Absorption Enhancers in the Drug Delivery Field
| Transmucosal Absorption Enhancers in the Drug Delivery Field |
| Autore | Maher Sam |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (406 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
absorption enhancement
absorption enhancer absorption enhancers absorption modifying excipients Aloe vera amino acid amphiphilic polymers and liposome antiepileptic drug antimicrobial peptide biocompatibility studies bioenhancer block copolymers brush border Caco-2 Caco-2 cells cationic functionalization cell-penetrating peptide cell-penetrating peptide (CPP) cervicovaginal tumors chitosan chitosan derivatives claudin clinical trial CNS disorders combined microsphere compound 48/80 confocal laser scanning microscopy cornea curcumin cyclodextrin cytochrome P450 drug absorption enhancer drug administration drug delivery efflux enterocyte epithelial permeability epithelial transport epithelium F-actin FITC-dextran formulation gel gemini surfactant GLP-1 hydrophobization imatinib in situ hydrogel in vivo studies insulin intestinal absorption intestinal delivery intestinal epithelial cells intestinal permeation enhancers KLAL man mast cell activator metabolism mucoadhesion mucoadhesiveness N-dodecyl-?-D-maltoside (DDM) nanocapsules nanocrystals nanomedicine nanoparticle nanoparticles nasal nasal delivery nasal formulation nasal permeability nasal vaccination nose to brain delivery nose to brain transport nose-to-brain ocular conditions ocular delivery ocular drug delivery ophthalmology oral delivery oral macromolecule delivery oral peptides osteoporosis P-glycoprotein penetration enhancer penetration enhancers permeability permeation enhancer permeation enhancers pharmacokinetic interaction pharmacokinetics PN159 polymeric micelles poorly absorbed drug preclinical PTH 1-34 pulmonary quaternization safety salcaprozate sodium sheep simulated intestinal fluid simvastatin small intestine sodium caprate sodium cholate (NaC) sugar-based surfactants teriparatide thermogel system tight junction tight junction modulator tight junctions transepithelial electrical resistance transferrin transmucosal drug delivery transmucosal permeation tryptophan vaccine adjuvant vaginal delivery whole leaf |
| ISBN | 3-03921-849-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910372785603321 |
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Maher Sam
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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