Drug delivery technology development in Canada / / special issue editors, Kishor M. Wasan, Ildiko Badea |
Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
Descrizione fisica | 1 electronic resource (352 p.) |
Disciplina | 615.1/900971 |
Soggetto topico | Drug Delivery Systems - Canada |
Soggetto non controllato |
encapsulation
biodistribution pharmaceutics targeted therapies gambogic acid GE11 peptide formulation and dosage form development transient modulation ROESY NMR spectroscopy bioaccessibility polymeric micelle pharmacological Inhibitors of HIF-1 and STAT3 nanoparticles Vitamin D drug discovery EGFR-targeted therapy translational research clinical trials doxorubicin dissolution drug development permeation enhancers Canada plant primary central nervous system lymphomas photostabilizers head and neck squamous cell carcinoma mouse models drug delivery systems melphalan hypoxia-induced chemoresistance skin virus circadian clock child friendly formulation adenanthin co-delivery canola oil deodorizer distillate Metaplex innovation controlled drug delivery nifedipine radiolabeling amphotericin B biological barriers blood-brain barrier (BBB) biologicals lipid nanoparticles oral formulation phytosterols medical devices chronotherapy oral cationic gemini surfactant route of administration drug delivery intra-arterial chemotherapy developing world sustained delivery water miscible solvents combination therapy antibodies throughput magnetic fields liposomes medulloblastoma drug-resistant melanoma rosmarinic acid topical formulation TNO gastrointestinal model gastrointestinal simulator malignant gliomas transdermal drug delivery oral delivery precision medicine 3D spheroid flavonoids staurosporine DOX-Vit D loading gradients bacteriophage phospholipid complex triggered drug release HIF-1 phage display pharmacokinetics emulsion quercetin cisplatin parasitic infections remote loading HAV6 cadherin peptide blood-brain barrier inclusion complex tocopherols STAT3 ultrasound liposome fungal infections magnetic resonance imaging (MRI) MG63 model orange juice radiation cancer mefloquine small molecules |
ISBN | 3-03928-005-8 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910367736503321 |
MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Regional Intestinal Drug Absorption : Biopharmaceutics and Drug Formulation |
Autore | Gonzalez-Alvarez Maria Isabel |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (238 p.) |
Soggetto topico |
Medicine
Pharmaceutical industries |
Soggetto non controllato |
bioequivalence
Biopharmaceutics Classification System in vitro dissolution test pravastatin oral absorption in silico modeling GastroPlus Phoenix WinNonlin pharmacokinetics clinical studies ibuprofen manometry gastrointestinal mechanistic modeling PBPK PBBM disintegration dissolution enteric-coated ICH quality control regional intestinal permeability permeation enhancers absorption-modifying excipients oral peptide delivery intestinal perfusion pharmaceutical development controlled release drug product biopharmaceutics classification system drug solubility drug permeability location-dependent absorption segregated flow intestinal model (SFM) traditional model (TM) route-dependent intestinal metabolism first-pass effect drug-drug interactions DDI in vitro in vivo extrapolations IVIVE zero-order absorption first-order absorption combined zero- and first-order absorption transit compartment absorption model in situ perfusion microdevices shape mucoadhesion colon absorption nutrient digestion nutrient absorption gastrointestinal hormone postprandial glycaemia energy intake region of the gut obesity type 2 diabetes Franz–PAMPA BCS drugs biomimetic membrane Franz cell passive drug transport BCS class IV drugs segmental-dependent intestinal permeability intestinal absorption oral drug delivery biopharmaceutics physiologically-based pharmacokinetic (PBPK) modeling furosemide intestinal permeability human colon carcinoma cell layer (Caco-2) hierarchical support vector regression (HSVR) drug absorption drug solubility/dissolution regional/segmental-dependent permeability and absorption |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Regional Intestinal Drug Absorption |
Record Nr. | UNINA-9910566462603321 |
Gonzalez-Alvarez Maria Isabel | ||
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Transmucosal Absorption Enhancers in the Drug Delivery Field |
Autore | Maher Sam |
Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (406 p.) |
Soggetto non controllato |
chitosan
intestinal epithelial cells ocular delivery amphiphilic polymers cornea tight junction modulator cyclodextrin permeability gemini surfactant transferrin compound 48/80 epithelial permeability cervicovaginal tumors nanoparticles confocal laser scanning microscopy safety formulation salcaprozate sodium intestinal absorption FITC-dextran curcumin block copolymers nasal vaccination whole leaf brush border ocular drug delivery vaccine adjuvant nanoparticle nasal delivery efflux permeation enhancers absorption enhancers nose to brain delivery small intestine epithelium CNS disorders absorption modifying excipients insulin absorption enhancer gel intestinal delivery thermogel system Caco-2 biocompatibility studies absorption enhancement man PN159 poorly absorbed drug tryptophan tight junction oral macromolecule delivery penetration enhancer intestinal permeation enhancers nanocrystals simvastatin nanomedicine enterocyte N-dodecyl-?-D-maltoside (DDM) cell-penetrating peptide quaternization KLAL nasal nasal permeability transmucosal drug delivery Caco-2 cells mast cell activator penetration enhancers drug delivery nose-to-brain bioenhancer polymeric micelles mucoadhesion cell-penetrating peptide (CPP) simulated intestinal fluid vaginal delivery nasal formulation pharmacokinetic interaction sodium caprate clinical trial transmucosal permeation drug absorption enhancer sugar-based surfactants nanocapsules imatinib teriparatide osteoporosis hydrophobization F-actin combined microsphere transepithelial electrical resistance oral delivery ocular conditions metabolism antimicrobial peptide permeation enhancer drug administration antiepileptic drug amino acid in vivo studies sodium cholate (NaC) epithelial transport preclinical nose to brain transport pharmacokinetics chitosan derivatives ophthalmology tight junctions sheep cationic functionalization GLP-1 pulmonary and liposome cytochrome P450 claudin P-glycoprotein in situ hydrogel mucoadhesiveness PTH 1-34 Aloe vera oral peptides |
ISBN | 3-03921-849-2 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910372785603321 |
Maher Sam | ||
MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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