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A Personalized Medicine Approach to the Diagnosis and Management of Autism Spectrum Disorder
| A Personalized Medicine Approach to the Diagnosis and Management of Autism Spectrum Disorder |
| Autore | Frye Richard E |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (416 p.) |
| Soggetto topico |
Medicine
Neurosciences |
| Soggetto non controllato |
fecal metabolites
ASD microbiome gastrointestinal symptoms Fisher Discriminant Analysis digital biomarkers wearables time series analysis autism social dyads socio-motor parameters network connectivity non-linear complex dynamics stochastic analysis autism spectrum disorders copy number variants females Array-Comparative Genomic Hybridization (Array-CGH) autism spectrum disorder Ehlers-Danlos syndrome hypermobility spectrum disorders autonomic disorder mast cell activation syndrome genetic testing chromosomal microarray analysis whole exome sequencing whole genome sequencing clinical utility polygenic risk scores Temple Grandin biomarker omics precision medicine proteomics transcriptomics epigenetics metabolomics patient stratification mitochondria oxidative stress prenatal environment immune dysfunction immunoglobulin G intravenous immunoglobulin energy metabolism fatty acid oxidation acyl-carnitines resveratrol integrative model concomitant condition disorder autism spectrum disorder (ASD) genomics personalized treatment strategy single nucleotide polymorphisms clinical decision support tool ADHD PANDAS OCD anxiety folate receptor alpha folates pregnancy brain development fetal development cobalamin glutathione methylation methylcobalamin redox metabolism locked-in network syndrome resting-state functional magnetic resonance imaging temporal lobe epilepsy amygdala brain COVID-19 children cytokines flavonoids inflammation luteolin mast cells microglia SARS-CoV-2 stress nutraceuticals survey vitamins minerals B12 folinic acid quality of life parents intervention systematic review medical claims logistic regression analysis retrospective analysis associated risk monoamine neurotransmitters neurotransmitter deficiency cerebral folate deficiency folate receptor alpha autoantibodies leucovorin α-amylase cortisol heart rate variability neuromodulation sleep anxiety transdermal electrical neuromodulation neurostimulation |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595075503321 |
Frye Richard E
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Abiotic Stress Effects on Performance of Horticultural Crops
| Abiotic Stress Effects on Performance of Horticultural Crops |
| Autore | Sebastiani Luca |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (126 p.) |
| Soggetto non controllato |
heat
polyphenols stomatal conductance shelf-life transpiration productivity transcription ornamental plants cold green areas flowering agronomic tools gas exchange ornamental prolonged storage transpiration greenhouse production dormancy temperature irradiance chilling requirements qPCR phenolics lodging hypoxia salinity relative humidity signal transduction chlorophyll fluorescence leaf water saturation deficit solar radiation plant choice partial root zone drying drought electro-conductivity growth flavonoids transpiration efficiency cloning oxidative stress breeding |
| ISBN | 3-03921-751-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367747703321 |
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Sebastiani Luca
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Metabolic Mechanisms of Aging and Its Related Diseases
| Advances in Metabolic Mechanisms of Aging and Its Related Diseases |
| Autore | Aquilano Katia |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (119 p.) |
| Soggetto topico |
Science: general issues
Physiology |
| Soggetto non controllato |
senescence
glucose metabolism lipid metabolism mitochondria oxidative stress aminoacid metabolism signaling |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557712903321 |
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Aquilano Katia
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Nanomaterials in Biomedicine
| Advances in Nanomaterials in Biomedicine |
| Autore | Ryabchikova Elena I |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (472 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
bone marrow-derived mesenchymal stromal cells
rAAV vectors carbon dots SOX9 TGF-β cartilage repair silver nanoparticles Entada spiralis Ceiba pentandra antibacterial assay catalytic dye reduction osteoarthritis human articular cartilage polymeric micelles pro-inflammatory cytokines IL-1β TNF-α nanomaterials nanomedicine immunotherapy oncotherapy immune-checkpoint inhibitors immunogenic cell death nano-vaccines nano-conjugates immune response oxidative stress antioxidants nanoparticles biological nano-antioxidants gold nanoparticles radiation chemotherapy radiosensitizer drug delivery system chemoradiotherapy magnetoliposomes hydrogels magnetolipogels self-assembly fluorescence Förster resonance energy transfer polypropylenimine dendrimers polyethylenimines tyrosine-modified polypropylene-imines tyrosine-modified polyethlyenimines PPI-Y siRNA transfection polymeric nanoparticles carbosilane dendron triazine amphiphile vesicles pH-sensitive doxorubicin methotrexate leukaemia molecular ultrasound nanobubbles active targeting targeted microbubbles angiogenesis inflammation thrombosis clinical translation molecular imaging liver fibrosis diagnosis therapy theranostics targeted drug delivery lipid conjugates amphiphilic oligonucleotides phosphoryl guanidines nucleic acid delivery leukemia iron nanoparticles RNA-Seq cytotoxicity polymers biodegradable drug delivery pharmaceutical SQUID magnetic properties iron content magnetite nanoparticles superoxide aorta heart nano-biomaterials nanotechnology scaffolds hard tissue engineering AuNPs AuPEI-NPs AuBSA-NPs electron microscopy ultrastructure of HepG2 cells and spheroids ultrastructure of HEK293 cells and spheroids penetration of NPs into monolayer and spheroids gold nanostars photothermal therapy photoacoustic imaging computed tomography cancer theranostic agents biocompatible nanomaterials diagnostics nanocarriers tissue engineering |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557724003321 |
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Ryabchikova Elena I
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advancing Knowledge on Cyanobacterial Blooms in Freshwaters
| Advancing Knowledge on Cyanobacterial Blooms in Freshwaters |
| Autore | Kormas Konstantinos Ar |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (202 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
blooms
cyanobacteria control toxins phenyl-acyl compounds caffeic acid non-toxic redox microcystin LR Microcystis aeruginosa logistic equation max algal population hydrodynamic mass transfer ecological function ecosystems harmful cyanobacterial bloom (CyanoHAB) proper functioning condition (PFC) total maximum daily load (TMDL) non-point source (NPS) point source (PS) Oregon Department of Environmental Quality (ODEQ) best management practice (BMP) stream-lake linkage taxonomic bacterial community environmental change mitten crab culture cyanobacteria community seasonal variation environmental factors potentially harmful species Lake Guchenghu man-made surface water channel transboundary nestedness Balkan Dolichospermum lemmermannii microcystin Lake Ludoš dissolved inorganic nitrogen dissolved organic carbon phosphonate subsurface methane maximum stoichiometry Synechococcus cyanobacterial growth stress responses Pseudanabaena galeata oxidative stress antioxidative enzymes freshwater bloom air temperature nutrients model subtropical reservoir functional groups phytoplankton seasonal succession cyanobacterial bloom water quality human and animal health climate change eutrophication |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557900103321 |
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Kormas Konstantinos Ar
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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AMP-Activated Protein Kinase Signalling
| AMP-Activated Protein Kinase Signalling |
| Autore | Neumann Dietbert |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (452 p.) |
| Soggetto non controllato |
HDACs
transcription epigenetics spermatozoa par complex A769662 MDCK skeletal muscle AID phosphorylation energy metabolism monocytes autophagy CML liver hindlimb suspension pregnancy preeclampsia gestational diabetes mellitus CaMKK2 assisted reproduction techniques nutrient-sensing signals sonic hedgehog protein acetylation glycogen storage disease AMPK adenosine monophosphate-activated protein kinase AICAR indirect calorimetry IL-1? MyHC I(?) HDAC4/5 endothelial cells infection hepatocyte p70S6K lipid metabolism host defense exercise kidney disease heat shock protein ?RIM mycobacteria activation loop developmental origins of health and disease (DOHaD) CREB TAK1 metabolic-inflammation phenylephrine AMP-activated protein kinase (AMPK) KATs 2-methoxyestradiol DNA methylation NLRP3 pump ?-linker steatosis AMPK kinase stress endothelial nitric-oxide synthase vasodilation adherent junctions epithelial cells glycogen Akt synaptic activation cellular energy sensing glucose uptake transporter co-expression atrophy nutrigenomics motility vasoconstriction fatty acid oxidation oxidative stress AS160 membrane histone modification sirtuin 1 (SIRT1) chromatin remodeling insulin signalling dietary fatty acids ULK CMML adaptive thermogenesis mTOR MDS mechanical unloading AML endothelial function medulloblastoma PKA adipose tissue NAD+ membranes nutrition ZO-1 TBC1D4 adipocyte soluble Adenylyl cyclase metabolism renin-angiotensin system energy utilization proteasome differentiation signaling peroxisome proliferator-activated receptor gamma coactivator 1-? (PGC1?) hypertrophy AMP-activated protein kinase metabolic disease LKB1 soleus muscle macrophages Immediate early genes CBS benign motor endplate remodeling ionomycin nectin-afadin tight junctions resveratrol protein kinase B regrowth mitochondria protein synthesis energy deficiency catechol-O-methyltransferase fiber-type microarrays carrier acetyl-CoA hypertension 3T3-L1 hypothalamus food intake |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346858503321 |
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Neumann Dietbert
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Anti-aging Nutrients with Health Beneficial Effects
| Anti-aging Nutrients with Health Beneficial Effects |
| Autore | Katakura Yoshinori |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (202 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Food & society |
| Soggetto non controllato |
raw-milk cheese
Caenorhabditis elegans longevity oxidative stress DAF-16 p38 MAPK anthocyanins structure glucose and lipid metabolism human health meta-analysis telomerase reverse transcriptase keratinocyte–hair follicle stem cell interaction exosomes telogen–anagen transition hair cycle regulation caffeine intestinal aging anti-aging vitellogenesis mitochondrial function oxidative stress response GABA exosome gut-brain interaction Caco-2 SH-SY5Y argan press-cake MITF JNK cAMP/PKA Wnt/β-catenin microarray analysis maslinic acid muscle atrophy muscle strength denervation olive peel SGLT1 transporter tangeretin cardamonin intestinal epithelial cell Phgdh liver l-serine deficiency insulin signaling glucose tolerance inflammaging aging related disorders low grade inflammation nutrients natural herbs pro-inflammatory cytokines regulatory T cells retinaldehyde dehydrogenase IgA quercetin luteolin |
| ISBN | 3-0365-5070-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910619467703321 |
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Katakura Yoshinori
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Anti-inflammatory Activity of Plant Polyphenols 2.0
| Anti-inflammatory Activity of Plant Polyphenols 2.0 |
| Autore | Dell'Agli Mario |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (120 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
flavonoids
inflammation p53 cancer prevention Nrf2 pathway anti-oxidant verbascoside polyphenols insulin-producing cells diabetes UPR oxidative stress ER-stress PERK anti-inflammatory mitochondria antioxidants marine algae anti-viral activity mechanism of action Antirhea borbonica kidney fibrosis caffeic acid antioxidant enzymes DESI-imaging curcumin glioblastoma cells radiation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576880903321 |
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Dell'Agli Mario
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Anticancer Drugs 2021
| Anticancer Drugs 2021 |
| Autore | Meegan Mary J |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (594 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
thymidylate synthase
cytotoxicity 1,2,3-triazole 1,3,4-oxadiazole 5-fluoruracil pemetrexed docking 3,4'-bis-guanidino 3-amino-4'-guanidino diphenyl ether phenyl pyridyl ether intramolecular hydrogen bond cancer cell viability HL-60 BRAF apoptosis thieno[2,3-d][1,2,3]triazine acetamide H1299 HER2 EGFR Bcl-2 inhibitors Indole-based analogues benzimidazole MTT cytotoxic assay cell cycle analysis DNA fragmentation ELISA solid/lipid nanoparticles phenstatin letrozole tubulin polymerisation inhibitor aromatase inhibitor breast cancer hybrid molecule dual-targeting molecule designed multiple ligand NaMSA cyclophosphamide histopathology testis urinary bladder anticancer agents enantioselective synthesis gastric adenocarcinoma tryptophanol concentration-guided dosing model informed dosing physiologically based pharmacokinetics sorafenib tyrosil-DNA-phosphodiesterase 1 adamantane resin acid TDP1 cytotoxic agents apoptosis induction HT-29 cells MDA-MB-231 cells mechanism prediction STAT inhibitors miR-21 hydrazide derivatives nitrogen scaffolds mitoxantrone cardiotoxicity inflammation oxidative stress age cumulative dose Trk NTRK tissue-agnostic larotrectinib entrectinib Trk fusion protein kinase inhibitors USFDA cancer patent review generic product doxazosin MD simulations combretastatin A-4 cytotoxic activity hybrid compounds indazole mucin MUC1 MUC16 immunotherapy cancer vaccine CAR (chimeric antigen receptor) ADC (antibody-drug conjugate) thiourea interleukin-6 trypan blue assay chalcones exportin-1 covalent binding CovDock anticancer activity xanthone in vitro in vivo isolation synthesis heterocyclic compound benzenesulfonamides imidazoles alkylated colony formation tumor spheroids HDAC inhibitors chalcone dual inhibitors carvedilol kidney toxicity 7-deaza-4'-thioadenosine derivatives multi-kinase inhibitor anticancer nucleoside Imiquimod drug efflux multidrug resistance Toll-Like Receptor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576874303321 |
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Meegan Mary J
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Anticancer Properties of Natural and Derivative Products
| Anticancer Properties of Natural and Derivative Products |
| Autore | Lupiáñez José Antonio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (312 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
total phenolic content
total flavonoid content GC-MS DPPH antioxidant anticancer agent anti-inflammatory agent gingival fibroblasts oral cancer natural extract Adenosma bracteosum extract anti-cancer cell line isolated compounds caspase-3 bioactive compounds metabolites wine grapes breast cancer chemoprevention chemotherapy squamous cell carcinoma Moringa oleifera 3-hydroxy-β-ionone antioxidant activity antioxidant enzymes anti-proliferative activity maslinic acid melanoma Olea europaea L. ROS levels photodynamic therapy cancer photosensitiser natural compounds Elaeagnus angustifolia EMT apoptosis AKT/PI3K signaling pathway human hepatocarcinoma HepG2 cells migration activity proliferation oxidative stress ROS level uvaol lung metastases in vivo complementary medicine medicinal mushrooms triterpenoic acid tormentic acid betulinic acid oleanolic acid rhodamine B cytotoxicity hepatocellular carcinoma (HCC) Pogostemon cablin (PPa extract) cell cycle synergism natural photosensitive compounds anticancer activity hypericin emodin quinizarin danthron interaction DNA glioblastoma (GBM) lactucopicrin (LCTP) temozolomide (TMZ) autophagy NF-κB p62/SQSM1 natural product therapeutic triglyceride xenograft study Caveolin-1 actin cytoskeleton betulin glycoconjugates click chemistry 1,3-dipolar cycloaddition |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557370303321 |
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Lupiáñez José Antonio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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