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Impaired Mitochondrial Bioenergetics under Pathological Conditions
| Impaired Mitochondrial Bioenergetics under Pathological Conditions |
| Autore | Lenaz Giorgio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (460 p.) |
| Soggetto topico |
Biochemistry
Biology, life sciences Research & information: general |
| Soggetto non controllato |
aging
aging heart assembly factor ATP synthase ATP synthase/hydrolase atypical myopathy Barth syndrome Bcl-2 family bioenergetics C cancer cardiolipin cardiomyopathy cell culture cell signaling cellular bioenergetics cellular signaling complex I assembly complex I deficiency complex I structure complex III COVID-19 cristae cytochrome b diabetes Dilated Cardiomyopathy with Ataxia electron transport chain energy metabolism entorhinal cortex equine primary myoblasts exercise fatty acid oxidation fibroblasts frozen tissue G mutation glucagon heart failure high-resolution respirometry human disease immune system influenza innate immune response insulin Leigh syndrome leukocytes lipoxidation-derived damage m.3243A> m.8909T> mammalian complex I mathematical model MAVS MDA5 metabolic disease mitochondria mitochondrial disease mitochondrial diseases mitochondrial DNA mitochondrial dynamic mitochondrial dynamics mitochondrial dysfunction mitochondrial permeability transition pore mitochondrial proteostasis MT-ATP6 MTCYB mutations n/a NADH dehydrogenase nephropathy neurodegeneration oleate oxidative damage oxidative phosphorylation oxidative stress oxygen consumption palmitate pancreatic endocrine cells pet mutants platelets programmed cell death protein import respiratory chain respiratory complex assembly respiratory complexes respiratory supercomplexes respirometry RIG-I ROS RSV Saccharomyces cerevisiae SARS CoV-2 Sengers syndrome skeletal muscle supercomplexes supernumerary subunits toxicity assays viral infections yeast |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585934503321 |
Lenaz Giorgio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Ionizing Radiation, Antioxidant Response and Oxidative Damage: Radiomodulators
| Ionizing Radiation, Antioxidant Response and Oxidative Damage: Radiomodulators |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2023 |
| Descrizione fisica | 1 online resource (322 p.) |
| Soggetto topico |
Medicine and Nursing
Pharmacology |
| Soggetto non controllato |
3T3 fibroblasts
acute gamma irradiation amino acid sequences antioxidant antioxidant defense system apoptosis ATP Auranofin bacterial dietary supplement bioinformatics bone marrow injury bone marrow microenvironment C57Bl/6 mice cancer cellular stress combination therapy dysbiosis electron beam radiation electron paramagnetic resonance (EPR) ferulic acid FT-IR gene signature GSH H2O2 human lactoferrin hyperthermia hypoxia immune response intestine ionising radiation ionizing radiation irradiation leukocytes MDA melatonin microbiome microbiota mitigation model animal mtDNA-mutations mucositis n/a nDNA-repair normal tissue nuclear and radiological emergencies Olea europaea L. cv. Caiazzana oleacein oncometabolites open field test oxidation stress oxidative modification profiling oxidative phosphorylation oxidative stress oxygenation pancreatic cancer peroxiredoxin peroxiredoxin 6 pharmacologic ascorbate planarians Prdx6 proliferation protection proteomic analysis radiation radiation biodosimetry radiation biomarker radiation response radiobiology database radiomitigator radiomitigators radiomodulation radionuclide scavengers radioprotection radioprotector radioprotectors radioresistance radiosensitization radiotherapy reactive oxygen species regeneration senescence serum albumin serum homeostasis spleen stem cell senescence stilbenoid survival rate synergistic effect Tameron thioredoxin thioredoxin reductase total body irradiation transcriptomics vitamin C X-ray radiation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Ionizing Radiation, Antioxidant Response and Oxidative Damage |
| Record Nr. | UNINA-9910743282503321 |
| MDPI - Multidisciplinary Digital Publishing Institute, 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitochondria in Health and Diseases
| Mitochondria in Health and Diseases |
| Autore | Javadov Sabzali |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (434 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
2-oxoglutarate dehydrogenase
4-HNE adenine nucleotide translocase ADP/ATP carrier aging amino acid neurotransmitter ancient mutation antioxidant system antioxidants apoptosis BAX BCL-2 BKCa channels cardiolipin cardiomyocytes cardioprotection cerebellar amino acid metabolism cholangiocellular carcinoma colon complex I (CI) deficiency cyclosporin A cytoskeletal proteins DDE dentate granule cell development dextran DRP1 dsRNA electron and confocal microscopy electron tunneling (ET) energy metabolism epilepsy ERK1/2 ETC complexes fatty acid oxidation ferritin gemfibrozil GW9662 H9c2 cardiomyoblasts healthy cells heart hepatic fibrogenesis hepcidin high-fat diet hippocampus HtrA2/Omi human amniotic membrane human diseases hyperforin hypoglycemia hypoxia inflammation innate immunity inorganic phosphate interferon response intranuclear mitochondria ion homeostasis iron overload ischemia reperfusion injury JNK KmADP Langendorff LHON life span lipid droplet lipid handling liver LONP1 metabolome and proteome profiling mitochondria mitochondria bioenergetics mitochondria calcium buffering mitochondria permeability transition pore mitochondria: energy metabolism mitochondrial cell death mitochondrial connexin 43 mitochondrial dynamics mitochondrial dysfunction mitochondrial function mitochondrial gene expression mitochondrial homeostasis mitochondrial interactions mitochondrial permeability transition pores mitochondrial UCP2 morphology mtDNA mtDNA transcription mtRNA muscle aging myocardial neuron death neuroprotection oxidative phosphorylation oxidative stress perilipin 5 physical performance pilocarpine pioglitazone PKA plectin post-transcriptional mtRNA processing potassium channel pravastatin protein phosphatases pyruvate dehydrogenase pyruvate dehydrogenase kinase reactive oxygen species reactive oxygen species (ROS) reactive oxygen species stress redox state regeneration respirasome assembly respiratory supercomplexes ROS rosiglitazone seizure Siberian population signaling signaling pathways siRNA sodium dichloroacetate specific genetic background telomerase activity telomere length tensile strength transferrin tricarboxylic acid cycle tubulin beta TUNEL TZD uncoupling uncoupling protein ZIP |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557577203321 |
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Javadov Sabzali
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Regulation of Central Carbon and Amino Acid Metabolism in Plants
| Regulation of Central Carbon and Amino Acid Metabolism in Plants |
| Autore | Timm Stefan |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (182 p.) |
| Soggetto topico |
Research & information: general
Technology: general issues |
| Soggetto non controllato |
2-phosphoglycolate
abiotic stress response acclimation Arabidopsis Arabidopsis thaliana Archaeplastida C3 cycle C4 photosynthesis Calvin-Benson cycle chlorophyll a fluorescence Crassulacean acid metabolism (CAM), evolution Cyanobacteria cyclic electron flux development energy balancing environmental adaptation evolution fluctuating light glycine decarboxylase glycolate oxidase Glycolate oxidase glycolysis malate valve MCF metabolite signaling/acclimation mitochondrial carriers n/a natural variation oxidative phosphorylation PEP carboxylase phosphoglycolate phosphatase photoperiodic changes photorespiration photosynthesis Portulaca grandiflora Portulacaceae protein phosphorylation pyruvate kinase redox-regulation respiratory metabolism TCA cycle transporters Zea mays |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557355703321 |
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Timm Stefan
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tuberculosis Drug Discovery and Development 2019
| Tuberculosis Drug Discovery and Development 2019 |
| Autore | Riccardi Giovanna |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (296 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
anti-TB drug pipeline
anti-virulence compounds antibiotic antimicrobial drug resistance (AMR) antimycobacterial antituberculosis agents artificial pneumothorax BCG bedaquiline biomarkers Carlo Forlanini caseum cell envelope clinical studies clinical trial CTVD delpazolid discovery DNA gyrase dormancy DprE1 inhibitor drug combination drug development drug discovery drug resistance drug-drug interactions EDCTP electron transport chain energy metabolism genomics granulomas host-directed therapy IAVI in vitro in vivo isoniazid lead generation lipidomics macozinone mechanism of action mechanisms of resistance metabolomics MID3 mode of action multi-drug resistance mutations mycobacteria mycobacterium Mycobacterium tuberculosis n/a oxidative phosphorylation pharmacodynamics pharmacokinetics phenotypic screening PknB PknG post-treatment sequelae privileged targets promiscuous targets proteomics pulmonary rehabilitation Q203 rifampin structure-based drug design surgery target target identification target-based drug design target-based screening TB TBVI toxicity transcriptomics tuberculosis tuberculosis treatment tuberculosis vaccines |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557627203321 |
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Riccardi Giovanna
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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