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Application of Bioinformatics in Cancers
| Application of Bioinformatics in Cancers |
| Autore | Brenner J. Chad |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (418 p.) |
| Soggetto topico | Biotechnology |
| Soggetto non controllato |
activation induced deaminase
AID/APOBEC alternative splicing anti-cancer artificial intelligence bioinformatics Bioinformatics tool biomarker discovery biomarker signature biomarkers biostatistics brain brain metastases breast cancer breast cancer detection breast cancer prognosis Bufadienolide-like chemicals cancer cancer biomarker cancer biomarkers cancer CRISPR cancer modeling cancer prognosis cancer treatment cancer-related pathways cell-free DNA chemotherapy circulating tumor DNA (ctDNA) classification clinical/environmental factors colorectal cancer comorbidity score Computational Immunology concatenated deep feature copy number aberration copy number variation curation curative surgery datasets decision support systems deep learning denoising autoencoders differential gene expression analysis diseases genes DNA DNA sequence profile drug resistance epigenetics erlotinib estrogen extreme learning false discovery rate feature extraction and interpretation feature selection firehose functional analysis gefitinib gene expression analysis gene inactivation biomarkers gene loss biomarkers gene signature extraction genomic instability GEO DataSets head and neck cancer health strengthening herb hierarchical clustering analysis high-throughput analysis histopathological imaging histopathological imaging features HNSCC hormone sensitive cancers HP hTERT imaging independent prognostic power interaction intratumor heterogeneity knockoffs KRAS mutation locoregionally advanced machine learning meta-analysis methylation microarray miRNA miRNAs mitochondrial metabolism mixture of normal distributions molecular mechanism molecular subtypes Monte Carlo mortality multiple-biomarkers mutable motif mutation Neoantigen Prediction network analysis Network Analysis network pharmacology network target neurological disorders next generation sequencing observed survival interval omics omics profiles oral cancer ovarian cancer overall survival pancreatic cancer pathophysiology PD-L1 precision medicine predictive model protein R package RNA self-organizing map single-biomarkers single-cell sequencing skin cutaneous melanoma somatic mutation StAR steroidogenic enzymes survival analysis TCGA TCGA mining telomerase telomeres The Cancer Genome Atlas traditional Chinese medicine transcriptional signatures treatment de-escalation tumor tumor infiltrating lymphocytes tumor microenvironment variable selection |
| ISBN | 3-03921-789-5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367743403321 |
Brenner J. Chad
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Fibroblast Growth Factor Receptor (FGFR) Signaling Pathway in Tumor
| Fibroblast Growth Factor Receptor (FGFR) Signaling Pathway in Tumor |
| Autore | Holzmann Klaus |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (276 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
adenocarcinoma of the esophagogastric junction
AKT anticancer astrocytoma autocrine signaling autophagy brain cancer breast cancer cancer cancer signaling cancer-associated fibroblasts coreceptor ERK ERK1/2 estrogen FGF FGF-mediated signaling FGF18 FGF19 FGF2 FGF8 FGFR FGFR1 FGFR2 FGFR2c FGFR4 fibroblast growth factor fibroblast growth factor receptors FRS2 gastric cancer gene regulation GPER HCC HEK293 immunohistochemistry infigratinib sensitivity inhibitors JNK1 keratinocyte kinase inhibitor LY2874455 malignant glioma malignant pleural mesothelioma melanoma membrane proteins monoclonal antibody MTOR n/a negative feedback loop neoadjuvant therapy neurite outgrowth NVP-BGJ398 optogenetics overall survival PC12 phosphorylation prognosis receptor cross-talk receptor kinase resistance review sarcoma seborrheic keratosis serine signaling skin small molecule Sprouty proteins squamous and basal cell carcinoma structure targeted therapy tumor promoter tumor suppressor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Fibroblast Growth Factor Receptor |
| Record Nr. | UNINA-9910557898903321 |
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Holzmann Klaus
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Multimodal Therapy of Upper Gastrointestinal Malignancies
| Multimodal Therapy of Upper Gastrointestinal Malignancies |
| Autore | Ronellenfitsch Ulrich |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (272 p.) |
| Soggetto topico | Public health and preventive medicine |
| Soggetto non controllato |
adjuvant therapy
Barrett's esophagus cancer dormancy chemo-radiotherapy clinical pathways complications conversion surgery definitive chemoradiotherapy early adenocarcinoma of esophagus endoscopic mucosal resection endoscopic submucosal dissection esophageal anastomosis esophageal cancer esophageal squamous cell carcinoma esophagectomy failure to rescue gastrectomy gastric cancer gastric surgery gastric/gastroesophageal cancer gastro-esophageal reflux disease gastrointestinal stromal tumor gastrointestinal tract genetic diagnosis genetics GIST imatinib immunotherapy induction chemotherapy Lauren histotype lymph node ratio MALT lymphoma minimally invasive surgery mortality mucosal resection multidisciplinary multimodal treatment n/a neoadjuvant chemoradiotherapy neoadjuvant chemotherapy neoadjuvant therapy neoadjuvant treatment neuroendocrine tumor nuclear receptor NR2F1 nutritional status oncological gastrectomy organ preservation outcome outcomes overall survival perioperative chemotherapy quality of care radiosensitivity relapse-free survival sarcopenia skeletal muscle index squamous cell esophageal cancer standardization stomach submucosal dissection survival |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557781603321 |
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Ronellenfitsch Ulrich
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Biomarkers of Gastrointestinal Cancer
| Novel Biomarkers of Gastrointestinal Cancer |
| Autore | Shimura Takaya |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (248 p.) |
| Soggetto topico |
Medicine
Oncology |
| Soggetto non controllato |
colorectal cancer
advanced adenoma screening stool mRNA cancer screening cirrhosis AFP machine learning MALDI-TOF proteomics CXCR4 prognosis overall survival rectal cancer neoadjuvant chemoradiation mouse model biomarkers urokinase plasminogen activator (uPA) urokinase plasminogen activator receptor (uPAR) plasminogen activator inhibitor type 1 (PAI-1) circulating tumour cell (CTC) gastric cancer oesophageal cancer serine proteases tumour microenvironment serpins biomarker chemoresistance liquid biopsy microRNA long non-coding RNA colorectal neoplasms cancer screening tests early detection of cancer precision medicine unfolded protein hepatocellular cancer GSVA unfolded protein score epigenetic regulation genes somatic mutations molecular genetic markers extracellular vesicles microbiome 16S rRNA amplicon metagenomics liver fibrosis hepatocellular carcinoma recurrence SHG/TPEF microscopy artificial intelligence advanced gastric cancer targeted therapy urinary miRNA miR-129-1-3p miR-566 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595076103321 |
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Shimura Takaya
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Precision Medicine in Solid Tumors
| Precision Medicine in Solid Tumors |
| Autore | Dey Nandini |
| Descrizione fisica | 1 online resource (304 p.) |
| Soggetto topico |
Medicine and Nursing
Oncology |
| Soggetto non controllato |
adjuvant chemotherapy
anaplastic lymphoma receptor tyrosine kinase breast cancer cancer cancer-associated fibroblasts cfDNA chemotherapy circulating free DNA clinical guideline clonality classification comprehensive genomic profiling CTC ctDNA DDR genes Decision tree digital enrichment driver mutation EGFR mutation EGFR-TKI electronic records epidermal growth factor receptor extent of resection gene panel sequencing glioblastoma prognosis HNSCC immune checkpoint inhibitors immunocytochemistry immunotherapy intratumor heterogeneity laboratory-friendly liquid biopsy molecular barcoding molecular genotyping multiple biopsies n/a new drug development next-generation sequencing next-generation sequencing (NGS) NGS non-small cell lung cancer open data osimertinib outcome overall survival parallel double-detection PARP inhibitors PD-L1 pediatric tumors personalized precision oncology precision medicine presumed germline findings random forest regulatory reform resistance screening sequencing smoking solid cancer strategic therapeutic intervention targeted therapy tDNA thymoma TMB TNBC subtypes triple-negative breast cancer (TNBC) tumor evolution tumor mutational burden tumor profiling test tyrosine kinase inhibitor universal health-care system whole-exome sequencing |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595078103321 |
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Dey Nandini
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| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Renal Cell Carcinoma
| Renal Cell Carcinoma |
| Autore | López José I |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (500 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
11) translocation renal cell carcinoma
ALK AMP-activated protein kinases anaplastic lymphoma kinase rearrangement aurora A biomarker cancer immunotherapy cancer-specific survival CDKN1A expression checkpoint inhibitors chromophobe renal cell carcinoma chromosomal loss chronic kidney disease circular RNAs in a clinico-genomic predictive model clear cell renal cell carcinoma clear cell Renal Cell Carcinoma collecting duct carcinoma copy number alteration copy number analysis copy number loss curcumin cytoreductive nephrectomy diagnostic and prognostic markers drug sensitivity efficacy emerging entity EMT like eosinophilic variant ESC everolimus EVI1 experimental validation of circular RNA FISH FOXO3 gene expression gene signature genetic association ghrelin glutathione metabolism glutathione transferase omega 1 glutathione transferase omega 2 glycomarkers glycoproteomics HOT hyperosmolality identification of circular RNAs IL-1? IL-2 IL13R?1 IL4R? immune checkpoint inhibitors immune infiltration immunohistochemistry immunotherapy inflammation markers integrins intratumour heterogeneity invasion JAK2 kidney kidney cancer label-free LOT metabolic reprogramming metabolome metabolome profiling metastasis metastatic ccRCC microRNA miR-133b miR-146a-5p miR-155-5p MiT family translocation renal cell carcinoma MMP-9 MMP10 molecular genetic features MTA2 mTOR mTOR inhibitors mutation N-glycomapping n/a nephrectomy new entity NK cells oncocytic renal tumor overall survival pale cell Papillary renal cell carcinoma (pRCC) patient survival PBRM1 PD-L1 pentose phosphate pathway PI3K/Akt/mTOR polybromo-1 polymorphism PPP practical approach predictive factors predictive role pro-IL-1? prognosis prognostic factors programmed death-ligand 1 proliferation proteome profiling Raf/MEK/ERK RCC recurrence free survival recurrence-free survival renal cancer renal cell renal cell cancer renal cell carcinoma review RNA sequencing sarcomatoid SMAD proteins solute carrier proteins statins survival survival prediction t(6 targeted therapy TCA cycle TCGA TFE3 TFEB TFEB-amplified renal cell carcinoma toxicity transforming growth factor beta tumor adhesion tumor microenvironment tumor migration tumor slice culture tyrosine kinase inhibitors unclassified renal cell carcinoma unclassified renal tumor uric acid urine VEGF inhibitors von Hippel-Lindau Xp11 translocation renal cell carcinoma |
| ISBN | 3-03928-639-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404087003321 |
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López José I
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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