Molecular mechanisms of body water homeostasis / / Carolyn M. Ecelbarger, Dharmendra Kumar Chaudhary, Hwal Lee, Swasti Tiwari
| Molecular mechanisms of body water homeostasis / / Carolyn M. Ecelbarger, Dharmendra Kumar Chaudhary, Hwal Lee, Swasti Tiwari |
| Autore | Ecelbarger Carolyn M. |
| Pubbl/distr/stampa | [San Rafael, California] : , : Morgan & Claypool, , 2017 |
| Descrizione fisica | 1 online resource (112 pages) : color illustrations |
| Disciplina | 572.3 |
| Collana | Colloquium series on integrated systems physiology |
| Soggetto topico |
Osmoregulation
Water in the body Body Water |
| Soggetto non controllato |
water homeostasis
total body water kidney hydration aquaporin diabetes insipidus hyponatremia vasopressin osmolality |
| ISBN | 1-61504-733-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
1. Water, water everywhere -- 1.1 Chapter overview -- 1.2 Body water composition -- 1.2.1 Changes in water homeostasis over the lifespan -- 1.2.2 Body water intake requirements -- 1.3 Measurement of total body water (TBW) -- 1.3.1 Body water compartmentalization -- 1.4 Dehydration -- 1.4.1 Exercise and water requirements -- 1.5 Environmental modulators of body water composition -- 1.5.1 High altitude -- 1.5.2 Extremes in temperature or humidity -- 1.5.3 Dietary alterations --
2. The brain, AVP, and water balance -- 2.1 Chapter overview -- 2.2 The brain -- 2.3 Vasopressin and related neuropeptides -- 2.3.1 Regulation of vasopressin production and release -- 2.4 Vasopressin receptors -- 2.4.1 Receptor cloning -- 2.4.2 Receptor activation and signaling -- 2.4.3 Receptor localization -- 2.5 Vasopressin actions -- 2.5.1 Vasopressin and glomerular filtration rate (GFR) -- 2.5.2 Vasopressin and blood pressure control -- 2.5.2.1 AVPR2 are coupled to nitric oxide generation -- 2.5.2.2 Hypertension may correlate with urinary concentrating ability -- 3. Renal control of water reabsorption -- 3.1 Chapter overview -- 3.2 Blood filtration -- 3.3 The countercurrent multiplier mechanism -- 3.3.1 The Na-K-2Cl cotransporter (NKCC2) -- 3.3.2 Gradient in the inner medulla -- 3.4 The collecting duct -- 3.5 Urea transporters -- 3.6 Renal aquaporins -- 3.6.1 Aquaporin 1 -- 3.6.2 Aquaporin 2 -- 3.6.2.1 Short-term AQP2 regulation -- 3.6.2.2 Long-term AQP2 regulation -- 3.6.2.3 Regulators of AQP2 -- 3.6.3 Aquaporins 3 and 4 -- 3.6.4 Other aquaporins -- 4. Hyponatremia -- 4.1 Chapter overview -- 4.2 Causes and forms of hyponatremia -- 4.3 Hyponatremia and the brain -- 4.4 Hyponatremia and bone health -- 4.5 The syndrome of inappropriate antidiuretic hormone (SIADH) -- 4.5.1 Exercise-induced hyponatremia -- 4.6 Vasopressin escape and molecular mechanismS -- 4.7 Therapies/interventions -- 5. Diabetes insipidus -- 5.1 Chapter overview -- 5.2 Central diabetes insipidus (CDI) -- 5.3 Nephrogenic diabetes insipidus (NDI) -- 5.3.1 Mutations in the vasopressin V2 receptor -- 5.3.2 Mutations in AQP2 -- 5.4 Acquired NDI -- 5.5 Treatments for DI -- 6. Additional pathophysiological states associated with impaired water balance -- 6.1 Chapter overview -- 6.2 Heart failure -- 6.3 Hypertension -- 6.4 Cirrhosis of the liver -- 6.5 Compulsive water drinking -- 6.6 Burn injuries -- 6.7 Medications that alter fluid dynamics -- 6.7.1 Diuretics -- 6.7.2 Aquaretics -- 6.7.3 Peroxisome proliferator-activated receptor, subtype [gamma] (PPAR [gamma]) agonists -- References -- Author biographies. |
| Record Nr. | UNINA-9910153635703321 |
Ecelbarger Carolyn M.
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| [San Rafael, California] : , : Morgan & Claypool, , 2017 | ||
| Lo trovi qui: Univ. Federico II | ||
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Neonatal Nutrition for Inflammatory Disorders and Necrotizing Enterocolitis
| Neonatal Nutrition for Inflammatory Disorders and Necrotizing Enterocolitis |
| Autore | Good Misty |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (232 p.) |
| Soggetto topico |
Biology, life sciences
Food & society Research & information: general |
| Soggetto non controllato |
bioactive
bloodstream infections breast milk breast-feeding breastfeeding breastmilk clinical outcomes colostrum administration communication donor breast milk donor human milk donor milk enteric pathogens exosome extracellular vesicle feeding formula formula feeding gastroschisis glycosaminoglycans growth hormones human milk human milk banks human milk fortifier immature intestine immunity inflammation intestinal adaptation intestinal atresia intestinal inflammation intestinal resection intestine late onset sepsis long chain polyunsaturated fatty acids meta-analysis microbiome milk analysis milk fat globule NEC necrotizing enterocolitis neonatal neonatal nutrition newborn NICU parent nutrition osmolality parenteral nutrition patient empowerment premature infants premature neonates prematurity preterm preterm infant product labeling short bowel syndrome spontaneous intestinal perforation very low birth weight |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557783303321 |
Good Misty
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Lo trovi qui: Univ. Federico II | ||
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The Tight Junction and Its Proteins : More Than Just a Barrier
| The Tight Junction and Its Proteins : More Than Just a Barrier |
| Autore | Fromm Michael |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (432 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
actomyosin
adherens junction adherens junctions aging AMP-activated protein kinase (AMPK) angubindin-1 angulin anhidrosis antibiotic-associated hemorrhagic colitis antibody antidiuretic hormone apical junctional complex apoptosis aquaporin arachnoid barrier atopic dermatitis atypical aPKCζ barrier formation barrier function biliary epithelial cells blood-biliary barrier blood-brain barrier blood-cerebrospinal fluid barrier brain barriers calcium permeability Campylobacter jejuni cancer caspase CaSR celiac disease cell growth cell polarity cell-cell contact cerebral cavernous malformation chemoresistance cholangiocellular carcinoma cholestasis chronic liver disease claudin Claudin claudin 1 claudin targeting claudin-1 claudin-12 Claudin-14 claudin-2 claudin-5 Claudin-7 claudins ClC-2 CLDN14 Clostridium perfringens enterotoxin Clostridium perfringens iota-toxin co-culture cochlear implantation collecting duct curcumin cytokines disease dorsal root ganglion drinking rate drug development drug discovery endometrial cancer endothelia endothelial barrier enterocyte enteropathogenic E. coli (EPEC) environmental sensors epidermal barrier epithelia epithelial barrier epithelial barrier dysfunction epithelial fluid transport epithelial sodium channel (ENaC), collecting duct cells epithelial to mesenchymal transition epithelium EspF fibrosis gene transcription gland dysfunction glia limitans hearing loss HELIX syndrome Hepatitis C Virus hepatocellular carcinoma human hydrogen peroxide hydrostatic pressure hypermagnesemia hypertrophy hypokalemia immune cells in silico inflammation inflammatory bowel disease interleukin 13 intestinal mucosa intestine ion channel ion reabsorption ion transport ischemia junctional adhesion molecule kidney kidney stones Klebsiella oxytoca lipolysis-stimulated lipoprotein receptor (LSR) liver lung MAGUK proteins MDCK C7 cells MEKK3 membrane proteins metastasis mice migration molecular dynamics monocytes mouse colon mucosal immunology mucus mutations Mz-ChA-1 cells nephropathy nerve injury NES neuropathic pain neurovascular unit NFκB NHE2 NISCH syndrome NLS occludin organ preservation osmolality osmoregulation paracellular paracellular barrier paracellular channels and barriers paracellular permeability paracellular sodium transport paracellular transport paracellular water transport pathogens PDZ domain permeability phosphatidylcholine phosphorylation polarity proliferation protein domain protein interactions protein structure proximal tubule quercetin reconstructed human epidermis repair retinal pigment epithelium retinopathy Rho RhoA ROCK sensor single molecule localization microscopy skin sorting nexin 9 (SNX9) STAT3 stem cell stimulated emission depletion structured illumination microscopy super-resolution microscopy thick ascending limb tight epithelium tight junction tight junction assembly tight junctions tight junctions (TJ) tissue barrier TNF transepithelial electrical resistance (TER) transplantation tricellular tight junction tricellular tight junctions tricellulin tumor tumor suppressor UBE2Z ubiquitin vestibular function viral entry WNK4 ZO-1 ZO-2 zonula occludens |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Tight Junction and Its Proteins |
| Record Nr. | UNINA-9910557404603321 |
Fromm Michael
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Lo trovi qui: Univ. Federico II | ||
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The Tight Junction and Its Proteins: More Than Just a Barrier : More Than Just a Barrier
| The Tight Junction and Its Proteins: More Than Just a Barrier : More Than Just a Barrier |
| Autore | Fromm Michael |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (412 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
actomyosin
adherens junction adherens junctions aging AMP-activated protein kinase (AMPK) angubindin-1 angulin anhidrosis antibiotic-associated hemorrhagic colitis antibody antidiuretic hormone apical junctional complex apoptosis aquaporin arachnoid barrier atopic dermatitis atypical aPKCζ barrier formation barrier function biliary epithelial cells blood-biliary barrier blood-brain barrier blood-cerebrospinal fluid barrier brain barriers calcium permeability Campylobacter jejuni cancer caspase CaSR celiac disease cell growth cell polarity cell-cell contact cerebral cavernous malformation chemoresistance cholangiocellular carcinoma cholestasis chronic liver disease claudin Claudin claudin 1 claudin targeting claudin-1 claudin-12 Claudin-14 claudin-2 claudin-5 Claudin-7 claudins ClC-2 CLDN14 Clostridium perfringens enterotoxin Clostridium perfringens iota-toxin co-culture cochlear implantation collecting duct curcumin cytokines disease dorsal root ganglion drinking rate drug development drug discovery endometrial cancer endothelia endothelial barrier enterocyte enteropathogenic E. coli (EPEC) environmental sensors epidermal barrier epithelia epithelial barrier epithelial barrier dysfunction epithelial fluid transport epithelial sodium channel (ENaC), collecting duct cells epithelial to mesenchymal transition epithelium EspF fibrosis gene transcription gland dysfunction glia limitans hearing loss HELIX syndrome Hepatitis C Virus hepatocellular carcinoma human hydrogen peroxide hydrostatic pressure hypermagnesemia hypertrophy hypokalemia immune cells in silico inflammation inflammatory bowel disease interleukin 13 intestinal mucosa intestine ion channel ion reabsorption ion transport ischemia junctional adhesion molecule kidney kidney stones Klebsiella oxytoca lipolysis-stimulated lipoprotein receptor (LSR) liver lung MAGUK proteins MDCK C7 cells MEKK3 membrane proteins metastasis mice migration molecular dynamics monocytes mouse colon mucosal immunology mucus mutations Mz-ChA-1 cells nephropathy nerve injury NES neuropathic pain neurovascular unit NFκB NHE2 NISCH syndrome NLS occludin organ preservation osmolality osmoregulation paracellular paracellular barrier paracellular channels and barriers paracellular permeability paracellular sodium transport paracellular transport paracellular water transport pathogens PDZ domain permeability phosphatidylcholine phosphorylation polarity proliferation protein domain protein interactions protein structure proximal tubule quercetin reconstructed human epidermis repair retinal pigment epithelium retinopathy Rho RhoA ROCK sensor single molecule localization microscopy skin sorting nexin 9 (SNX9) STAT3 stem cell stimulated emission depletion structured illumination microscopy super-resolution microscopy thick ascending limb tight epithelium tight junction tight junction assembly tight junctions tight junctions (TJ) tissue barrier TNF transepithelial electrical resistance (TER) transplantation tricellular tight junction tricellular tight junctions tricellulin tumor tumor suppressor UBE2Z ubiquitin vestibular function viral entry WNK4 ZO-1 ZO-2 zonula occludens |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Tight Junction and Its Proteins |
| Record Nr. | UNINA-9910674057303321 |
Fromm Michael
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||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Traumatic Brain Injury : Clinical Characteristics and Outcomes
| Traumatic Brain Injury : Clinical Characteristics and Outcomes |
| Autore | Badenes Rafael |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (176 p.) |
| Soggetto topico |
Medicine
Clinical & internal medicine |
| Soggetto non controllato |
traumatic brain injury
scoring system modified early warning score mortality psychometric properties patient-reported outcome measures classical test theory translation linguistic validation outcome instruments cerebral oximetry near-infrared spectroscopy cerebrovascular autoregulation intracranial pressure acute brain injury early tracheostomy late tracheostomy tracheostomy timing ventilatory acquired pneumonia prehospital oxygenation hypoxia hyperoxia emergency medical services osmolality traumatic brain injury (TBI) hypertonic saline mannitol osmolar gap brain death death by neurologic criteria cerebral blood flow CT angiography CT perfusion COVID-19 pandemic treatment efficiency emergency department seizure QTc interval spatial QTS-T angle brain–heart interaction cranioplasty cognitive improvement neuropsychology |
| ISBN | 3-0365-5528-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Traumatic Brain Injury |
| Record Nr. | UNINA-9910637792603321 |
Badenes Rafael
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Lo trovi qui: Univ. Federico II | ||
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