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Regional Intestinal Drug Absorption : Biopharmaceutics and Drug Formulation
| Regional Intestinal Drug Absorption : Biopharmaceutics and Drug Formulation |
| Autore | Gonzalez-Alvarez Maria Isabel |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (238 p.) |
| Soggetto topico |
Medicine
Pharmaceutical industries |
| Soggetto non controllato |
bioequivalence
Biopharmaceutics Classification System in vitro dissolution test pravastatin oral absorption in silico modeling GastroPlus Phoenix WinNonlin pharmacokinetics clinical studies ibuprofen manometry gastrointestinal mechanistic modeling PBPK PBBM disintegration dissolution enteric-coated ICH quality control regional intestinal permeability permeation enhancers absorption-modifying excipients oral peptide delivery intestinal perfusion pharmaceutical development controlled release drug product biopharmaceutics classification system drug solubility drug permeability location-dependent absorption segregated flow intestinal model (SFM) traditional model (TM) route-dependent intestinal metabolism first-pass effect drug-drug interactions DDI in vitro in vivo extrapolations IVIVE zero-order absorption first-order absorption combined zero- and first-order absorption transit compartment absorption model in situ perfusion microdevices shape mucoadhesion colon absorption nutrient digestion nutrient absorption gastrointestinal hormone postprandial glycaemia energy intake region of the gut obesity type 2 diabetes Franz–PAMPA BCS drugs biomimetic membrane Franz cell passive drug transport BCS class IV drugs segmental-dependent intestinal permeability intestinal absorption oral drug delivery biopharmaceutics physiologically-based pharmacokinetic (PBPK) modeling furosemide intestinal permeability human colon carcinoma cell layer (Caco-2) hierarchical support vector regression (HSVR) drug absorption drug solubility/dissolution regional/segmental-dependent permeability and absorption |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Regional Intestinal Drug Absorption |
| Record Nr. | UNINA-9910566462603321 |
Gonzalez-Alvarez Maria Isabel
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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State-of-the-Art Polymer Science and Technology in Italy (2019,2020)
| State-of-the-Art Polymer Science and Technology in Italy (2019,2020) |
| Autore | Blanco Ignazio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (338 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
polyhedral oligomeric silsesquioxanes
nanocomposites POSS polystyrene thermal behavior SEM analysis soy flour soy protein isolate insoluble carbohydrates periodate oxidation aldehydes generation condensation reactions soy adhesives biodegradable polymers rheological properties irrigation pipes soil burial test polyesters Bio-Flex® Mater-Bi® polymer degradation photo-oxidation pectin alginate biocomposites food packaging degradable films ionic liquids 3D printing digital light processing CO2 capture furanic polymer spectroscopy solid-state 13C-NMR FTIR Raman linear structure ring opening γ-lactone Diels-Alder SAS coprecipitation controlled drug delivery systems microparticles eudragit supercritical carbon dioxide dental materials composite resin layered double hydroxide calcium bentonite antibiofilm activity injection molding structure/properties relationship cavity temperature fast modulation chitosan cyclodextrin macromolecular complex dalargin enkephalin chymotrypsin NMR oral peptide delivery peptide stability cold-cure epoxy resins organic-inorganic hybrids sol-gel layered double hydroxides carbon nanotubes electrical properties polyphenols flavonoids furanics sulphur bio-polymers pentane heating value mulch films Ecovio® polylactide poly(butyleneadipate-co-butyleneterephtalate) polyethylene polymer melt primary and secondary relaxations Johari-Goldstein relaxation bond reorientation vibrational dynamics molecular-dynamics simulations UV-LED curing epoxy-acrylate resin biochar multiwalled carbon nanotubes composites reduced graphene oxide polyketone functionalization electrically-conductive nanocomposites UHMWPE wear tests bio-activity history cyclodextrin nanosponge crosslinked polymer diclofenac mefenamic acid molecular imprinting delayed addition binding isotherm binding selectivity imprinting factor polymers life cycle assessment polymeric materials sustainability plastic LCA additive manufacturing LCD printing epoxy polymer blends thermomechanical properties |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | State-of-the-Art Polymer Science and Technology in Italy |
| Record Nr. | UNINA-9910557114303321 |
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Blanco Ignazio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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