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Preclinical Evaluation of Lipid-Based Nanosystems
| Preclinical Evaluation of Lipid-Based Nanosystems |
| Autore | Silva Ana Catarina |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (351 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
acoustic response
alopecia areata ammonia atopic dermatitis biocorona biodistribution Box‒Behnken design breast cancer Caco-2 monolayer cancer cholesterol clarithromycin colon cancer therapy cyanocobalamin D-optimal design dexamethasone dialysis dissolution enhancement docohexaenoic acid DoE doxorubicin drug delivery drug release efavirenz ethyl cellulose ex vivo permeation fenofibrate flaxseed oil fluconazole follicular targeting formulation optimization FZD10 protein hyaluronic acid hydrophobic ion pairing intestinal permeation enhancers intoxication ligand distribution light activation lipid phase lipid polymer hybrid nanocapsules lipid vesicles lipid-based formulation lipolysis lipomers liposome liposomes melanoma mesoporous silica microbubble mobility N-alkylisatin n/a nanocarrier nanoemulsion(s) nanomedicine nanostructured lipid carriers nanostructured lipid carriers (NLC) nanotransfersome nasal route neuroinflammation neuroprotection non-ionic surfactants nose-to-brain oligonucleotide optimization oral drug delivery PAI-2 permeation pharmacokinetics phase-behavior phospholipid coating phospholipids porous microparticles psoriasis quality by design (QbD) rheological behavior rivastigmine self-emulsifying drug delivery systems SerpinB2 silica-lipid hybrid skin skin topical delivery solid dosage forms solid lipid nanoparticles spray drying stability supersaturation target delivery nanosystem transferosomes ulcer index ultrasound contrast agents urokinase plasminogen activator vegetable oils vitamin B12 zone of inhibition |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557544303321 |
Silva Ana Catarina
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Regional Intestinal Drug Absorption : Biopharmaceutics and Drug Formulation
| Regional Intestinal Drug Absorption : Biopharmaceutics and Drug Formulation |
| Autore | Gonzalez-Alvarez Maria Isabel |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (238 p.) |
| Soggetto topico |
Manufacturing industries
Medicine and Nursing |
| Soggetto non controllato |
absorption-modifying excipients
BCS class IV drugs BCS drugs bioequivalence biomimetic membrane biopharmaceutics biopharmaceutics classification system Biopharmaceutics Classification System clinical studies colon absorption combined zero- and first-order absorption controlled release drug product DDI disintegration dissolution dissolution test drug absorption drug permeability drug solubility drug solubility/dissolution drug-drug interactions energy intake enteric-coated first-order absorption first-pass effect Franz cell Franz-PAMPA furosemide gastrointestinal gastrointestinal hormone GastroPlus hierarchical support vector regression (HSVR) human colon carcinoma cell layer (Caco-2) ibuprofen ICH in silico modeling in situ perfusion in vitro in vitro in vivo extrapolations intestinal absorption intestinal perfusion intestinal permeability IVIVE location-dependent absorption manometry mechanistic modeling microdevices mucoadhesion nutrient absorption nutrient digestion obesity oral absorption oral drug delivery oral peptide delivery passive drug transport PBBM PBPK permeation enhancers pharmaceutical development pharmacokinetics Phoenix WinNonlin physiologically-based pharmacokinetic (PBPK) modeling postprandial glycaemia pravastatin quality control region of the gut regional intestinal permeability regional/segmental-dependent permeability and absorption route-dependent intestinal metabolism segmental-dependent intestinal permeability segregated flow intestinal model (SFM) shape traditional model (TM) transit compartment absorption model type 2 diabetes zero-order absorption |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Regional Intestinal Drug Absorption |
| Record Nr. | UNINA-9910566462603321 |
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Gonzalez-Alvarez Maria Isabel
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Supramolecular Systems for Gene and Drug Delivery
| Supramolecular Systems for Gene and Drug Delivery |
| Autore | Ostos Francisco José |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (218 p.) |
| Soggetto topico |
Chemistry
Research and information: general |
| Soggetto non controllato |
2-amino-4-(4-chlorophenyl)thiazole (AT)
adenine-uracil base pair aripiprazole block copolymers bovine serum albumin (BSA) cancer treatment carrier of therapeutic agents cationic calix[4]arenes complementary hydrogen bonded drug carrier system Congo red (CR) controlled drug delivery doxorubicin doxorubicin (Dox) drug delivery dynamic light scattering (DLS) elution volume (Ve) encapsulation ferritin folic acid gene expression gold nanoparticles half-life extension heat aggregated immunoglobulins (HAI) host:guest hydrophobic immunoglobulin light chain λ (Lλ) indocyanine green ITC liposomes long acting injectables magnetite nanoparticles magnetoliposomes microfluidics microparticles mRNA multi-walled carbon nanotube n/a NMR nucleic acids oral drug delivery PAMAM dendrimers phenylethylamine photothermal therapy pillararene poly(butylene adipate) poly(l-lactic acid) selective cytotoxicity supramolecular supramolecular nanogels supramolecular self-assembled ribbon-like structures (SRLS) sustained release synergistic strategy targeted drug delivery transfection efficiency tumor targeting β-cyclodextrin-based nanosponge |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566473003321 |
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Ostos Francisco José
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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