Info
- Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.
Brain-Targeted Drug Delivery
| Brain-Targeted Drug Delivery |
| Autore | Sousa Flávia |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (260 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
3D cell culture systems
acetaminophen Alzheimer's disease Alzheimer's disease-relevant tau species anti-tau and anti-receptor bispecific monoclonal antibodies blood-brain barrier brain biodistribution brain cancer brain targeted therapy central composite rotatable design cerebral open flow microperfusion cerebrospinal fluid microcirculation chemoattractant claudin-5 CNS drug delivery convection-enhanced delivery CXCL CXCR delivery to brain depression diffuse midline glioma drug delivery drug delivery into the brain electrochemical biosensors GB-13 gene therapy glioblastoma glioblastoma multiforme glycol chitosan high-grade glioma hyaluronidase IL-13 IL-13Rα2 IL13.E13K-PE4E immunotherapy immunotoxin improved memory interactions between Aβ and tau intranasal delivery laser liposome macromolecules memory impairment microdialysis microparticles movement impairment n/a nanoparticle nanoparticles nanostructured lipid carrier naringenin nasal delivery system neurosurgery non-human primate nose to brain delivery opioids optogenetics Parkinson's disease phospholipid oily gel PLGA polyplexes pomegranate seed oil receptor expression seizure targeted therapy tau clearance in microglia tau clearance in neurons temporal-spatial pathological Aβ and tau distribution tight junction tolcapone transendothelium based on receptor-mediated transcytosis ultrasound |
| ISBN | 3-0365-5281-2 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910619467203321 |
Sousa Flávia
|
||
| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Cannabis : Neuropsychiatry and Its Effects on Brain and Behavior
| Cannabis : Neuropsychiatry and Its Effects on Brain and Behavior |
| Autore | Colizzi Marco |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (204 p.) |
| Soggetto topico |
Medicine and Nursing
Neurosciences |
| Soggetto non controllato |
adolescents
aerobic fitness African American age of onset alcohol BDNF black cannabinoids cannabis cannabis use cannabis use disorder cannabis-associated psychosis CB1 CB2 clinical high risk cortical surface structure craving cue reactivity delta-9-tetrahydrocannabinol Delta-9-tetrahydrocannabinol disability dronabinol EEG EEG functional connectivity eLORETA endocannabinoid system episodic memory executive functions exercise fMRI frontal alpha asymmetry functional magnetic resonance imaging gender genetics gyrification inhibitory control interoception marijuana marijuana use memory migraine: chronic pain n/a negative reinforcement older adult opioids placebo problematic cannabis use psychotic disorder randomized controlled trial resting state schizophrenia surface area systematic review THC traumatic injury triple network triptans |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Cannabis |
| Record Nr. | UNINA-9910557129503321 |
|
Colizzi Marco
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Neurogenic Bowel Dysfunction
| Neurogenic Bowel Dysfunction |
| Autore | Krogh Klaus |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (242 p.) |
| Soggetto topico |
Medicine and Nursing
Neurology and clinical neurophysiology |
| Soggetto non controllato |
acute rehabilitation
adolescent adults alpha-synuclein ambulatory blood pressure measurement anorectal malformation autonomic autonomic dysfunction bowel dysfunction bowel function breath test cerebral palsy children chronic constipation cohort study constipation diabetes mellitus difficulty with evacuation exoskeletal walking faecal incontinence fecal incontinence food ingestion gastrointestinal glycopyrrolate gut microbiota imaging investigations iontophoresis laxatives low anterior resection syndrome manometry MENTOR motility multiple sclerosis NBD neostigmine neurogenic bowel neurogenic bowel dysfunction opioids parasympathetic Parkinson's disease pediatric pharmacological postprandial hypotension prevalence quality of life SCI SCI bowel management spina bifida spinal cord injury systematic review transanal irrigation treatment assessment urinary tract infection utilisation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585944903321 |
|
Krogh Klaus
|
||
| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Opioids and Their Receptors : Present and Emerging Concepts in Opioid Drug Discovery
| Opioids and Their Receptors : Present and Emerging Concepts in Opioid Drug Discovery |
| Autore | Spetea Mariana |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (358 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
(−)-N-phenethylnorhydromorphone analogs
[35S]GTPgammaS assay [Dmt1]DALDA 14-methoxycodeine-6-O-sulfate 1H-NMR experiments 6β-naltrexol abuse agonist allodynia analgesia analgesics antagonist arrestin recruitment beta-arrestin bias factor biased agonism biased agonist biased agonists biased ligands biased signaling bifunctional ligands binding binding affinity BNTX buprenorphine chronic constriction injury (CCI) codeine codeine-6-O-sulfate DADLE DALDA DAMGO delta opioid receptor dependence design and synthesis dihydrocodeine diphenethylamines docking dysbiosis fentanyl forskolin-induced cAMP accumulation assays functional assay G-protein bias heteromer hyperalgesia interaction fingerprints internalization inverse agonist ischemia kappa opioid receptor KGOP01 Leu-enkephalin loperamide lysosomes macrocyclic tetrapeptide mechanism elucidation misuse mitragynine molecular docking molecular dynamics molecular modeling & MOR and DOR agonists morphinan morphine mu opioid receptor mu receptor multifunctional ligands n/a naltrexone neonatal opioid withdrawal syndrome neurokinin-1 receptor neutral antagonist NTI derivative opioid opioid drugs opioid liabilities opioid peptide opioid peptides opioid peptides and peptidomimetics opioid receptors opioid side effects opioids over-the-counter drugs pain therapy partial agonism partial agonist peptide synthesis peripheral analgesic tolerance peripheral antinociception peripheral µ-opioid receptors pharmacology plasma stability potassium channels primary hippocampal culture PZM21 racemic synthesis of β2-amino acids receptor binding studies receptor model respiration respiratory depression selectivity simulation SR-17018 structure-activity relationships sulfonamide TAPP tolerance writhing test zerumbone β-arrestin recruitment assays β2-amino acids β2-Homo-amino acids δ opioid receptor δ opioid receptor antagonist μ opioid receptor µ opioid receptor µ-opioid receptor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Opioids and Their Receptors |
| Record Nr. | UNINA-9910557108003321 |
|
Spetea Mariana
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Recent Studies of Rodent Ultrasonic Vocalizations and Their Use in Experimental Models
| Recent Studies of Rodent Ultrasonic Vocalizations and Their Use in Experimental Models |
| Autore | Brudzynski Stefan M |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (352 p.) |
| Soggetto topico |
Medicine and Nursing
Neurosciences |
| Soggetto non controllato |
22 kHz calls
22 kHz vocalizations 22-kHz calls 50 kHz calls 50 kHz vocalizations 50-kHz calls 50-khz ultrasonic vocalizations (USVs) 6-OHDA ACTH addiction affect alarm call alpha-synuclein amphetamine animal model anxiety autism automated scoring aversion aversive state brain oscillations Brattleboro rat calcium Cav1.2 chemogenetics chronic variable stress (CVS) clozapine-n-oxide cognitive development communication corticosterone dam-pup interaction depression distress DJ1 dopamine drug development drug discovery emotional arousal emotional contagion ethanol evolution of vocalization exaggerated reactivity exercise fear contagion fear extinction female females fentanyl food generalization heart rate hedonia hyperreactivity hypervigilance individual differences infant isolation calls larynx machine learning male males maternal immune activation maternal separation mental health mesolimbic cholinergic system mesolimbic dopaminergic system microdialysis n/a negative geotaxis NOR nucleus accumbens observational fear learning opioids pain Parkinson's disease pathology pharmacology Pink1 play playback PTSD pup pup isolation rat rat pup rats respiration reward righting reflex rough-and-tumble play self-administration sex differences social approach social buffering social contact call social play ultrasonic vocalization ultrasonic vocalizations UMAP USV vasopressin antagonists vocalizations Wistar working memory Y maze |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557608903321 |
|
Brudzynski Stefan M
|
||
| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Research on Gang-Related Violence in the 21st Century
| Research on Gang-Related Violence in the 21st Century |
| Autore | Valasik Matthew |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (188 p.) |
| Soggetto topico |
Drugs trade / drug trafficking
Law |
| Soggetto non controllato |
civil gang injunctions
comparative research conflict network criminal behavior crisis desistance disaggregation drug markets ethnography focused deterrence gang gang homicide gang violence gangs generalized cross-entropy Good Lives Model homicide homicide types incident reports intervention latent class analysis n/a network composition opioids organized crime overdose police data prevention public health retaliation shootings social media social network analysis social networks spatial concentration street gang violence street gangs violence |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557372403321 |
|
Valasik Matthew
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The Role of PPARs in Disease
| The Role of PPARs in Disease |
| Autore | Wagner Nicole |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (274 p.) |
| Soggetto topico |
Medicine and Nursing
Physiology |
| Soggetto non controllato |
addiction
adipogenesis AKI alcohol Alzheimer's Alzheimer's disease (AD) angiogenesis animal models cancer cellular metabolism cilia CKD cognition coronary artery CYP450 cystogenesis dominant-negative isoform eicosanoids endothelial cells fatty acids fetal programming fibrosis folate growth suppressors human studies hypertrophic adipocytes hypertrophic obesity immortality immune system in vitro adipocytes inflammation inherited metabolic disorders insulin-resistance kidney ligand ligands lipidomics lipids metabolic syndrome metastasis metastasis formation modulators nephron nicotine non-alcoholic fatty liver disease (NAFLD) non-alcoholic steatohepatitis (NASH) nuclear receptors obesity opioids peroxisome proliferator activated receptors peroxisome proliferator-activated receptor peroxisome proliferator-activated receptor-γ coactivator-1α peroxisome proliferator-activated receptors (PPARs) peroxisome-proliferator activated receptors PGC-1α, disease pharmacology PKD PPAR PPARG isoforms PPARG splicing PPARs PPARα proliferation psychostimulants resistance to cell death risk factors RNA sequencing sex Sirtuin1 synthetic agonists therapy toxicology tumor angiogenesis tumor progression vascular vitamin B12 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566482503321 |
|
Wagner Nicole
|
||
| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||