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A Personalized Medicine Approach to the Diagnosis and Management of Autism Spectrum Disorder
| A Personalized Medicine Approach to the Diagnosis and Management of Autism Spectrum Disorder |
| Autore | Frye Richard E |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (416 p.) |
| Soggetto topico |
Medicine
Neurosciences |
| Soggetto non controllato |
fecal metabolites
ASD microbiome gastrointestinal symptoms Fisher Discriminant Analysis digital biomarkers wearables time series analysis autism social dyads socio-motor parameters network connectivity non-linear complex dynamics stochastic analysis autism spectrum disorders copy number variants females Array-Comparative Genomic Hybridization (Array-CGH) autism spectrum disorder Ehlers-Danlos syndrome hypermobility spectrum disorders autonomic disorder mast cell activation syndrome genetic testing chromosomal microarray analysis whole exome sequencing whole genome sequencing clinical utility polygenic risk scores Temple Grandin biomarker omics precision medicine proteomics transcriptomics epigenetics metabolomics patient stratification mitochondria oxidative stress prenatal environment immune dysfunction immunoglobulin G intravenous immunoglobulin energy metabolism fatty acid oxidation acyl-carnitines resveratrol integrative model concomitant condition disorder autism spectrum disorder (ASD) genomics personalized treatment strategy single nucleotide polymorphisms clinical decision support tool ADHD PANDAS OCD anxiety folate receptor alpha folates pregnancy brain development fetal development cobalamin glutathione methylation methylcobalamin redox metabolism locked-in network syndrome resting-state functional magnetic resonance imaging temporal lobe epilepsy amygdala brain COVID-19 children cytokines flavonoids inflammation luteolin mast cells microglia SARS-CoV-2 stress nutraceuticals survey vitamins minerals B12 folinic acid quality of life parents intervention systematic review medical claims logistic regression analysis retrospective analysis associated risk monoamine neurotransmitters neurotransmitter deficiency cerebral folate deficiency folate receptor alpha autoantibodies leucovorin α-amylase cortisol heart rate variability neuromodulation sleep anxiety transdermal electrical neuromodulation neurostimulation |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595075503321 |
Frye Richard E
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Actinomycetes : The Antibiotics Producers
| Actinomycetes : The Antibiotics Producers |
| Autore | Stegmann Evi |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (362 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Streptomyces
biogeography comparative genomics diversification secondary metabolite biosynthetic gene clusters SMGC natural products streptomyces rishirilide biosynthesis polyketides polynucleotide phosphorylase ribonuclease regulation promoter RNA decay polyadenylation (p)ppGpp antibiotic antibiotics geomicrobiology Illumina sequencing microbiome diversity Actinobacteria Cave microbiology secondary metabolite rare Actinobacteria Amycolatopsis unculturability siderophore glycopeptide antibiotics dbv cluster regulatory genes StrR LAL LuxR solo dalbavancin A40926 Streptomyces lividans secretion pathways secretory proteins signal peptides actinomycetes teicoplanin van resistance genes Streptomyces tsukubaensis tacrolimus FK506 omics screening secondary metabolism differentiation elicitors morphology liquid cultures metagenomics rare actinomycetes dereplication metabolomics genome mining secondary metabolites novel compounds physicochemical screening physical and chemical properties structural diversity biological activity Actinoallomurus antibiotics polyethers lysolipin minimal PKS II cyclases benz[a]naphthacene quinone tridecaketide aromatic polyketide pentacyclic angular polyphenol extended polyketide chain actinobacteria β-lactamase resistance β-lactamase inhibitor polyketide synthases acyltransferases engineering new bioactive compounds symbiosis drug discovery chemical ecology culture-based approaches strain specialized metabolites biosynthetic gene cluster |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Actinomycetes |
| Record Nr. | UNINA-9910557114803321 |
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Stegmann Evi
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antioxidants and Second Messengers of Free Radicals
| Antioxidants and Second Messengers of Free Radicals |
| Autore | Neven Zarkovic (Ed.) |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (194 p.) |
| Soggetto non controllato |
free radicals
lipids cell-based ELISA reactive aldehydes antioxidants fertility reactive oxygen species ROS human diseases lipid peroxidation 4-hydroxynonenal 1 4-Dihydropyridine Derivatives omics pathophysiology growth control cannabinoids plant extract mass spectrometry cell cultures cancer aging oxidative stress immunochemistry |
| ISBN | 3-03897-534-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346858303321 |
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Neven Zarkovic (Ed.)
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Application of Bioinformatics in Cancers
| Application of Bioinformatics in Cancers |
| Autore | Brenner J. Chad |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (418 p.) |
| Soggetto non controllato |
cancer treatment
extreme learning independent prognostic power AID/APOBEC HP gene inactivation biomarkers biomarker discovery chemotherapy artificial intelligence epigenetics comorbidity score denoising autoencoders protein single-biomarkers gene signature extraction high-throughput analysis concatenated deep feature feature selection differential gene expression analysis colorectal cancer ovarian cancer multiple-biomarkers gefitinib cancer biomarkers classification cancer biomarker mutation hierarchical clustering analysis HNSCC cell-free DNA network analysis drug resistance hTERT variable selection KRAS mutation single-cell sequencing network target skin cutaneous melanoma telomeres Neoantigen Prediction datasets clinical/environmental factors StAR PD-L1 miRNA circulating tumor DNA (ctDNA) false discovery rate predictive model Computational Immunology brain metastases observed survival interval next generation sequencing brain machine learning cancer prognosis copy number aberration mutable motif steroidogenic enzymes tumor mortality tumor microenvironment somatic mutation transcriptional signatures omics profiles mitochondrial metabolism Bufadienolide-like chemicals cancer-related pathways intratumor heterogeneity estrogen locoregionally advanced RNA feature extraction and interpretation treatment de-escalation activation induced deaminase knockoffs R package copy number variation gene loss biomarkers cancer CRISPR overall survival histopathological imaging self-organizing map Network Analysis oral cancer biostatistics firehose Bioinformatics tool alternative splicing biomarkers diseases genes histopathological imaging features imaging TCGA decision support systems The Cancer Genome Atlas molecular subtypes molecular mechanism omics curative surgery network pharmacology methylation bioinformatics neurological disorders precision medicine cancer modeling miRNAs breast cancer detection functional analysis biomarker signature anti-cancer hormone sensitive cancers deep learning DNA sequence profile pancreatic cancer telomerase Monte Carlo mixture of normal distributions survival analysis tumor infiltrating lymphocytes curation pathophysiology GEO DataSets head and neck cancer gene expression analysis erlotinib meta-analysis traditional Chinese medicine breast cancer TCGA mining breast cancer prognosis microarray DNA interaction health strengthening herb cancer genomic instability |
| ISBN | 3-03921-789-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367743403321 |
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Brenner J. Chad
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Artificial Intelligence Bioinformatics: Development and Application of Tools for Omics and Inter-Omics Studies
| Artificial Intelligence Bioinformatics: Development and Application of Tools for Omics and Inter-Omics Studies |
| Autore | Facchiano Angelo |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (175 p.) |
| Soggetto topico |
Science: general issues
Medical genetics |
| Soggetto non controllato |
artificial intelligence
bioinformatics genomics omics inter-omics machine learning data mining proteomics |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Artificial Intelligence Bioinformatics |
| Record Nr. | UNINA-9910557253003321 |
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Facchiano Angelo
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Metabolomics 2018
| Cancer Metabolomics 2018 |
| Autore | Pinto Joana |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (184 p.) |
| Soggetto non controllato |
cell transporters
pharmacodynamics cell growth in vitro study metabolomic signatures endometabolome lung cancer metabolomics chemometric methods bladder cancer mTOR metabolite profiling metabolic pathways hepatocellular carcinoma glutamate senescence MCF7 breath analysis bio actives biomarker gas chromatography–mass spectrometry (GC–MS) GC-MS lung omics nutraceuticals glutaminase metabolism acylcarnitines Erwinaze Kidrolase glutathione targeted metabolomics apoptosis SLC1A5 essential amino acids cancer progression ASCT2 HR MAS alanine analytical platforms volatile organic compound glutaminolysis isotope tracing analysis asparaginase vitamin E breast cancer prognosis early diagnosis tocotrienols NMR prostate cancer in vitro cancer MDA-MB-231 |
| ISBN | 3-03921-346-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367563603321 |
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Pinto Joana
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cell-Free Nucleic Acids
| Cell-Free Nucleic Acids |
| Autore | Nagy Bálint |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (248 p.) |
| Soggetto non controllato |
screening
single nucleotide polymorphism predictive and preventive approach PTEN cell-free DNAs fetal fraction gestational hypertension RASSF1 CDH1 RT-PCR cfDNA statistical models hematopoietic stem cell transplantation NanoString solid organ transplantation copy number variants sarcomas liquid biopsy obesity fetal DNA neutrophil extracellular traps mammography non-invasive prenatal testing ovarian cancer circulating miRNA pyrosequencing growth retardation preeclampsia gestational diabetes mellitus biomarker inflammatory bowel disease multi-level diagnostics PAX1 population study nuclease activity NETosis omics piRNA cell-free DNA prediction leiomyosarcomas network analysis NGS statistical methods circulating nucleic acids deletion/insertion polymorphism gender differences leiomyomas fetal growth restriction blood plasma exosomes miRNA pregnancy-related complications NIPT genetic marker cell-free nucleic acids extracellular vesicles expression next generation sequencing breast cancer individualized patient profile circulating tumor cells maternal serum screening personalized medicine embryo culture medium C19MC microRNA DNA cell-free RNAs z-score fetal cells microchimerism aging plasma |
| ISBN | 3-03928-075-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910372783603321 |
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Nagy Bálint
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Crop Breeding for Drought Resistance
| Crop Breeding for Drought Resistance |
| Autore | Luo Lijun |
| Pubbl/distr/stampa | Frontiers Media SA, 2019 |
| Descrizione fisica | 1 electronic resource (229 p.) |
| Soggetto topico |
Science: general issues
Botany & plant sciences |
| Soggetto non controllato |
drought-resistance
crop breeding genome-wide association study transcriptome phenotyping omics |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557242003321 |
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Luo Lijun
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| Frontiers Media SA, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Decreasing the Impact of Treatment Resistance in Schizophrenia: Identifying Novel Molecular Targets/ Pathways to Increase Treatment Efficacy
| Decreasing the Impact of Treatment Resistance in Schizophrenia: Identifying Novel Molecular Targets/ Pathways to Increase Treatment Efficacy |
| Autore | Manchia Mirko |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (177 p.) |
| Soggetto topico |
Science: general issues
Pharmacology |
| Soggetto non controllato |
omics
epigenetics pharmacogenetics CYP risk prediction microbiota |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Decreasing the Impact of Treatment Resistance in Schizophrenia |
| Record Nr. | UNINA-9910557214503321 |
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Manchia Mirko
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Fruit Metabolism and Metabolomics
| Fruit Metabolism and Metabolomics |
| Autore | Moing Annick |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (266 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Anacardium occidentale
fast phenotyping NIR UPLC-HRMS chemometrics Capsicum frutescens L. non-targeted metabolomics secondary metabolism Liquid Chromatography coupled to Mass Spectrometry (LC-MS) mulberry high resolution mass spectrometry antioxidant activity in vitro gastrointestinal digestion α-glucosidase inhibitory activity cytokinin fruit expansion kiwifruit phytohormone tomato metabolomics biochemical phenotyping priming BABA Botrytis cinerea Phytophthora infestans Pseudomonas syringae fruit pigmentation introgression lines mass spectrometry San Marzano landrace Davidson’s plum finger lime native pepperberry antioxidant amino acids GC×GC-TOFMS UHPLC-QqQ-TOF-MS/MS bush fruit genetic resources melon genotype by sequencing elemental analysis metabolome Cucumis melo pineapple ripening non-climacteric lipophilic compounds lipid-related genes lipid metabolism fruit postharvest quality traits stress biomarkers polyphenolics solanaceous crops capsicum annuum pepper eggplant fruit ripening tissue-specificity flavonoid wine clones Vitis vinifera sensory analysis fruit metabolomics developmental metabolomics stress metabolomics spatial metabolomics central metabolism specialized metabolism nuclear magnetic resonance spectroscopy omics multi-omics integration |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557111903321 |
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Moing Annick
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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