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Functionally Relevant Macromolecular Interactions of Disordered Proteins
| Functionally Relevant Macromolecular Interactions of Disordered Proteins |
| Autore | Simon Istvan |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (520 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
aggregation
CABS model co-evolution coarse-grained conformational plasticity copper binding correlated mutations decision tree based artificial neural network dehydron differentially regulated genes disorder-to-order regions disordered protein disordered protein platform DNA conformational landscape DNA-protein interactions drug discovery drugs dual threshold eIF4E epiproteome evolution evolutionary couplings extracellular FG-Nups fluorescence anisotropy folding functional analysis gene ontology analysis histone lysine methyltransferase homodimer HOTAIR hydration hydrogen bond immune inter-subunit interaction interaction surface intrinsic disorder intrinsic disorder prediction intrinsically disorder proteins intrinsically disordered intrinsically disordered protein intrinsically disordered proteins intrinsically disordered proteins (IDPs) intrinsically disordered region ion pair leukemia lncRNA MC simulations MEG3 membrane-less organelle meta strategy Microarray MLL proteins MLL4 molecular machines molecular recognition feature molten globule mutual synergistic folding N-terminal prion protein neurodegenerative disease neurodegenerative diseases Nuclear pore complex oligomer p300 HAT acetylation p53 phosphorylation physiological homeostasis plant virus post-translational modification post-translational modifications potyvirus prion disease mutations protein protein aggregation protein conformation protein hydrodynamics protein intrinsic disorder protein stability protein structure protein thermostability protein-protein interaction protein-RNA interactions residue co-variation residue contact network ribosomal protein RIN4 RNA binding RNA sequencing salt bridges secretion sequential DNA bending significance voting smFRET solvent-accessible surface area Sox2 sequential DNA loading spectroscopy stabilization center statistical force fields stress response structural disorder structural domain Tau fibrillation temperature response transcription factor dosage transcription factors transcriptome unstructured proteins VPg wide-line 1H NMR |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557509403321 |
Simon Istvan
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy
| Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy |
| Autore | Ruvo Menotti |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (278 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
adoptive immunotherapy
affibody molecules affinity aggregation AL amyloidosis amyloid anti-CD38 MoAb antibody antibody fragment antibody fragments Antibody-Drug Conjugate antibody-drug conjugates BCMA belantamab mafodotin bispecific bispecific T-cell engager blood-brain barrier cancer therapy CAR adaptor CD38 cDNA CHI3L1 chimeric antigen receptor (CAR T) chimeric antigen receptor T-cells cross-linking Daratumumab developability drug targeting E. coli Fab glutamate carboxypeptidase II guinea pig idecabtagene vicleucel immunization immunogenicity in vivo imaging Isatuximab JNJ-68284528 lung metastasis Mabs modular CAR T monoclonal antibodies monoclonal antibody myeloma NAALADase neurodegenerative disorders neurotoxicity non-specific binding nucleocapsid NUsc1 oligomer payload phage display pharmacokinetics polyspecificity porcine deltacoronavirus prostate cancer prostate-specific membrane antigen protein engineering protocol receptor-mediated transcytosis scFv self-association single chain solubility specificity split CAR stability transferrin receptor universal CAR T universal immune receptor viscosity YKL-40 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557613003321 |
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Ruvo Menotti
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Special Issue Dedicated to Late Professor Takuo Okuda : : Tannins and Related Polyphenols Revisited: Chemistry, Biochemistry and Biological Activities / / Takashi Yoshida, Tsutomu Hatano, Hideyuki Ito
| Special Issue Dedicated to Late Professor Takuo Okuda : : Tannins and Related Polyphenols Revisited: Chemistry, Biochemistry and Biological Activities / / Takashi Yoshida, Tsutomu Hatano, Hideyuki Ito |
| Autore | Yoshida Takashi |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (316 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Coreopsis lanceolata L.
UV-Vis methanogenesis Lythraceae flavanone grape marc TDDFT Ephedra sinica macrocyclic oligomer triple-negative breast cancer antioxidant purple prairie clover chalcone neuraminidase fatty acid synthase (?)-epigallocatechin gallate epidermal growth factor NMR spectroscopy Aluminum ion Onagraceae Hydrangea macrophylla synthetic analogues blue color development amyloid-? peptide FTIR oseltamivir carboxylate quantitative NMR phloroglucinolysis thin layer chromatography European historic leathers FASN inhibition ECD colorimetric tests taxanes cynandione A conservation method 5-O-caffeoylquinic acid ellagitannin PC12 condensed tannin Trapa taiwanensis Nakai 1H-NMR Acacia (?)-epigallocatechin 3-gallate Geranium thunbergii condensed tannins immunomodulatory effect Acacia mearnsii bark Escherichia coli oligomer Horner–Wadsworth–Emmons reaction lung tumor Aspergillus fumigates in vitro batch fermentation metal complex Myrtaceae Cynanchum auriculatum molecular interactions phenolic glycoside bamboo leaf extract stability Microsporum canis Cynanchum wilfordii thiolysis anti-inflammation hydrolysable tannin geraniin NGF polyphenol revision ESI-mass bioactivity antifungal activities interferon-? antitumor effect tannin composition oenothein B zanamivir 2-O-?-laminaribiosyl-4-hydroxyacetophenone anticancer activity proanthocyanidin vegetable tanning Dittrichia viscosa differentiation aurone antioxidants protein precipitation apoptosis polyphenolic FASN inhibitors forage legume biological activities ultrahigh-resolution negative mode MALDI-TOF mass spectrometry overlay method spectroscopy wattle tannin immune checkpoint hormesis 3-O-glucosyldelphinidin gallotannin proanthocyanidins fatty acids flavonol inhibition structure Candida spp Malassezia spp ORAC assay neuroprotection crystal structure tannins |
| ISBN |
9783038978350
3038978353 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346671803321 |
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Yoshida Takashi
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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