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Insulin-Like Growth Factors in Development, Cancers and Aging
| Insulin-Like Growth Factors in Development, Cancers and Aging |
| Autore | Werner Haim |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (196 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
IGF-I
IGF-II insulin IGF-IR IRs tyrosine kinase receptor GPCRs hybrids phosphorylation G-proteins β-arrestins functional RTK/GPCR hybrid nuclear translocation IGF-I receptor signaling targeted therapeutics IGF-Trap IGF system IGFBP-3 IGFBP-3R TMEM219 anti-tumor anti-metastatic agonists mAb therapy IGF-1 IGFBP-1 older adults longevity health-span age-related disease cognitive impairment diabetes mitochondria growth hormone insulin-like growth factor-1 aging oxidative stress senescence longitudinal study IGFBP mouse models skeletal muscle MSCs myogenesis glucose regulated protein (GRP) 94 insulin-like growth factor obligate chaperone hypertrophy atrophy cachexia muscle regeneration autophagy IGF-1R insulin receptor IR-A structural studies receptor activation |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557735703321 |
Werner Haim
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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P38 Signaling Pathway
| P38 Signaling Pathway |
| Autore | Cuenda Ana |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (194 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
arginine methylation
erythroid differentiation MKK3 phosphorylation, PRMT1 p38 MAPK cocaine conditioned place preference reward stress anxiety depression nucleus accumbens social interaction k opioid receptors p38α Rab5 endosome Alzheimer's Lewy Bodies amyloid-β tau α-synuclein p38-MAPK α inhibitor Alzheimer's disease synaptic plasticity neuroinflammation β-amyloid Tau Kv4.2 seizure temporal lobe epilepsy hippocampus neuronal firing and excitability p38MAPK nuclear translocation β-like importins inflammation cancer skeletal muscle energy metabolism signal transduction exercise type 2 diabetes p38 mitogen-activated protein kinase bleomycin-induced pulmonary fibrosis idiopathic pulmonary fibrosis RNA sequencing alveolar epithelial type II cells MAPK p38 physiology metabolism signaling hypoxia arrhythmia MAPK11 p38β |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557702003321 |
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Cuenda Ana
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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