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Cellular and Molecular Mechanisms of Nephropathic Cystinosis
| Cellular and Molecular Mechanisms of Nephropathic Cystinosis |
| Autore | Levtchenko Elena N |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (230 p.) |
| Soggetto topico |
Medicine and Nursing
Pharmacology |
| Soggetto non controllato |
3-dimensional models
apoptosis arterial spin labelling autophagy azoospermia biomarkers bone bone-muscle wasting CD34+ hematopoietic stem and progenitor cells cell and animal models cell model central nervous system chitotriosidase clinical course clinical trial cortical atrophy CTNS-pathogenic variants cysteamine cystine cystine blood level cystinosis disulfiram endocytosis endolysosome epithelial cell differentiation fertility fibroblast growth factor 23 fractures galectin-3 gene therapy genotype histopathology history hollow fiber membrane homeostasis hypogonadism infantile nephropathic cystinosis inflammasome interleukins investigational new drug application kidney kidney progenitors kidney proximal tubule leptin lysosomal storage disease lysosomal storage diseases lysosomal storage disorder macrophages mice mitochondrial distress mouse model nephropathic cystinosis newborn screening newborn screening for cystinosis novel therapies osteoclast osteoclasts pre-clinical studies programmed cell death proximal tubular cells sclerostin therapeutic monitoring treatment strategies for cystinosis zebrafish |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585941103321 |
Levtchenko Elena N
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Oxidative Stress in Diabetic Retinopathy
| Oxidative Stress in Diabetic Retinopathy |
| Autore | Ortega AÌngel Luis |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (322 p.) |
| Soggetto topico |
Medicine
Medicine and Nursing |
| Soggetto non controllato |
aging
angiogenesis antioxidant antioxidants apoptosis aqueous humor ascorbic acid astaxanthin biomarkers biomarkers of diabetic retinopathy blood-retinal barrier carotenoid Cinnamomi Ramulus CPA4-1 cyclooxygenase Cytochrome P450 db/db mice diabetes mellitus diabetic retinopathy diabetic retinopathy (DR) docosahexaenoic acid (DHA) eicosanoids eicosapentaenoic acid (EPA) epiretinal membrane extracellular vesicles fenofibrate free radicals GLP-1 glycation glyoxalase HDAC6 high-mobility group box 1 (HMGB1) human retina hyperglycemia inflammation inflammatory pathways internal limiting membrane lipoxygenase macular hole metabolic memory miRNA mitochondria n/a novel therapies Nrf2 occludin oxidative stress Paeoniae Radix photoreceptor photoreceptor cells PI3K proliferative diabetic retinopathy reactive oxygen species redox retinal disease retinal endothelial cell senescence retinal endothelial cells retinal pigment epithelium superoxide dismutase tear film thioredoxin tubastatin A vitamin D vitreoretinal surgery vitreous humor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557134903321 |
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Ortega AÌngel Luis
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Updates on Molecular Targeted Therapies for CNS Tumors
| Updates on Molecular Targeted Therapies for CNS Tumors |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2023 |
| Descrizione fisica | 1 online resource (368 p.) |
| Soggetto topico |
Medicine and Nursing
Oncology |
| Soggetto non controllato |
A172
A2AAR antagonist adenosine adenosine receptors antigen processing and presentation antioxidant apoptosis ATRX bevacizumab biomarker blood-brain barrier brain metastasis brain tumor cancer metabolism cell cycle arrest central nervous system chemotherapy CNS disease CNS lymphoma CpG island diffuse midline gliomas DNMT EGFR ependymoma EPHB2 epidermal growth factor receptor ERK/MAPK pathway FGFR3 G-CIMP GBM germline mutation glioblastoma glioblastoma molecular classification glioma Group A Group B H3K27M histone acetylation IDH-mutant glioma immune evasion immune score immunotherapy intraparenchymal metastases intrathecal isotope labeling KIF11 leptomeningeal low grade glioma low-grade glioma LPS lung cancer lung carcinoma lung malignancy mass spectrometry meningitis MET metastatic disease Metformin methotrexate methylation methylomics methyltransferases MGMT molecular targets molecular therapy monoclonal antibodies MYCN myxopapillary n/a neoantigen neoplastic neurofibromatosis NF1 novel therapeutics novel therapies patient avatars PCNSL PDGFRA pediatric brain tumor PFA PFB PI3K/PTEN pathway plexiform neurofibroma potential therapy development preclinical models progression progression-free survival radiotherapy receptor tyrosine kinase RELA stereotactic radiosurgery subependymoma T cells T lymphocytes targeted therapy temozolomide tumor microenvironment tumor mutation burden tumor suppressor tyrosine kinase inhibitors U87MG vestibular schwannoma Warburg effect whole-brain radiation therapy YAP1 ZFTA |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9911053032003321 |
| MDPI - Multidisciplinary Digital Publishing Institute, 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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