Autore	Uchino Junji
Pubbl/distr/stampa	Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021
Descrizione fisica	1 online resource (258 p.)
Soggetto topico	Medicine
Soggetto non controllato	adjuvant chemotherapy biomarker chemotherapy daily practice DNA polymerase beta docetaxel EGFR-TKI endocrine disorders epidermal growth factor receptor Expanded Access Program FDG-PET genomic diagnosis glucose transporter 1 HIP1R immune checkpoint inhibitor immune checkpoint inhibitors immune-related adverse events immunotherapy interstitial lung disease KRAS lung cancer lung neoplasms meta-analysis metastasis methylation multiple cancers mutation network meta-analysis nivolumab non-small cell lung cancer non-small-cell lung cancer nonsmall cell lung cancer NSCLC nucleotide-diphosphate kinase oligometastasis osimertinib PD-1 PD-1 blockade PD-1 inhibitors PD-L1 PD-L1 expression PD-L1 inhibitors phase I/II trial platinum-based first-line predictive biomarker previously treated patients prognosis prognostic factor prognostic factors pulmonary fibrosis pulmonary pleomorphic carcinoma RAD51B methylation radiology and other imaging real-world data rechallenge recurrence responsiveness retrospective analysis RUNX1 S-1 salvage surgery sequencing stage IIIA-N2 surgery survival T790M targeted therapy TP53 mutations tumor-bearing patients tyrosine kinase inhibitors unresectable β-catenin
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Altri titoli varianti	Non-small Cell Lung Cancer
Record Nr.	UNINA-9910557489703321

Autore	Sinha Raghu
Pubbl/distr/stampa	Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021
Descrizione fisica	1 online resource (272 p.)
Soggetto topico	Medicine and Nursing
Soggetto non controllato	acute myeloid leukemia bioinformatics biomarker Boolean model brain-tumor-initiating cell (BTIC) breast cancer cancer genomics cancer progression cancer stem cells cancer systems biology circulating miR-1246 clinical trials CNV computational methods diagnostic biomarker differential expression docking drug repurposing drug resistance Elk-1 Ets ETS Ets-1 experimental model systems genomics glioma glycomics glycosaminoglycan binding knockdown lung adenocarcinoma lung adenocarcinoma (LUAD) lung cancer lung squamous cell carcinoma (LUSC) metabolomics metagenomics microarray n/a network next-generation sequencing non-small-cell lung cancer omics optical genome mapping ovarian pancreatic cancer patient survival patient-derived organoids patient-derived xenografts PEA3 personalized medicine PI3K-Akt signaling pathways prognosis prognostic biomarker protein interactome proteomics renal cancers risk group Sestrin2 signature single-cell sequencing SNV solid tumors stem cell survival systems biology TargetScan TCGA transcriptomics triple-negative breast cancer UBE2C virtual screening
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Record Nr.	UNINA-9910557768503321

Autore	Fanti Stefano
Pubbl/distr/stampa	Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021
Descrizione fisica	1 online resource (312 p.)
Soggetto topico	Medicine
Soggetto non controllato	18F-FACBC 18F-FDG PET/CT 68Gallium-PSMA PET/CT adipose tissue Adoptive biochemical recurrence biomarker biomarkers bladder cancer breast breast cancer castrate resistant prostate cancer CD8-Positive T-Lymphocytes circulating miRNAs circulating tumor cells computed tomography Computer-assisted diagnosis concurrent chemoradiotherapy consensus CTLA-4 Antigen cystic tumor DCFBC DCFPyL Deauville criteria diagnosis diagnostic imaging diffuse large B-cell lymphoma diffusion diffusion kurtosis imaging diffusion tensor imaging diffusion-weighted imaging dynamic 18F-FDG PET/CT dynamic contrast-enhanced magnetic resonance imaging EBV empyema epistemology FDG FDG-PET/CT follow up glioblastoma gold nanoparticle guidelines head and neck cancer head and neck neoplasms heat shock protein 70 Hodgkin lymphoma Hounsfield unit HPV imaging imaging parameters immune checkpoint inhibitors immunotherapy Immunotherapy International Consensus Guidelines intraductal papillary mucinous neoplasms locally advanced cervical cancer machine learning magnetic resonance imaging malignant pleural mesothelioma mantle cell lymphoma marker mCRPC meningioma Mesothelin meta-analysis metastatic breast cancer miRNA expression molecular imaging Molecular imaging MRI n/a neovascularization neuroimaging non-small-cell lung cancer noninvasive imaging NSCLC nuclear medicine optimal cutoff level ovarian cancer overutilization p16 pancreatic neoplasms pathologic pazopanib PD-1 PD-L1 PDAC PERCIST perfusion PET PET/CT PET/MRI PI-RADS pleural dissemination pleural effusion positron emission tomography positron-emission tomography precision oncology prognosis programmed cell death 1 receptor prostate prostate cancer prostate-specific-antigen PSA kinetics thresholds PSMA PSMA-1007 radiation therapy radioactive tracers radiogenomics radiomic radiomics radionuclide imaging radionuclide therapy Radium-223 receptor status recurrence relapse response assessment response to therapy response to treatment review sdAbs single-photon emission computed tomography soft tissue sarcoma (STS) somatostatin receptor SPECT imaging SPECT/CT spectral-CT squamous cell carcinoma of the head and neck staging survival SUV SUVmax targeted therapy texture analysis Therapy response assessment treatment response triple negative breast cancer two-tissue compartment model upper tract urothelial carcinoma urothelial carcinoma VCAM-1 XOFIGO Yin Yang 1
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Record Nr.	UNINA-9910557432103321

Autore	Stefanachi Angela
Pubbl/distr/stampa	Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022
Descrizione fisica	1 electronic resource (416 p.)
Soggetto topico	Research & information: general Biology, life sciences
Soggetto non controllato	EGR-1 flavonoid (E)-5-((4-oxo-4H-chromen-3-yl)methyleneamino)-1-phenyl-1H-pyrazole-4-carbonitrile MDA-MB-231 MMP9 TNFα pancreatic ductal adenocarcinoma cyclodextrin inclusion complex phase solubility studies preformulation studies biphenylnicotinamide derivatives dual inhibitor EGFR VEGFR2 ligand-based pharmacophore molecular docking molecular dynamics leukemias doxorubicin inflammation drug delivery tumor targeting elastin-like polypeptide cell penetrating peptide matrix metalloproteinase doxorubicin resistance photosensitizer delivery system PAMAM dendrimer photodynamic therapy cytotoxicity phototoxicity colorectal adenocarcinoma dicarboximides chemical synthesis apoptosis kinases anticancer gene profiling SAR biomarkers colorectal cancer early detection examination liquid biopsy personalized medicine tumor treatment exosomes ctDNA CTC cytotoxic activity pyrazole derivatives MTT assay ADMET analysis single-crystal diffraction FTIR spectroscopy NMR spectroscopy thermogravimetric analysis acute myelogenous leukemia platelets microparticles γδ T cells immunotherapy tumor resistance combination therapy tumor microenvironment immune checkpoint inhibitor neuroblastoma molecular iodine cyclophosphamide xenografts metronomic therapy tamoxifen CYP2D6 MCF-7 Ishikawa cells SERM TNBC uterotrophic α-mangostin poly(amidoamine) dendrimer targeted drug delivery biotin targeting glioblastoma multiforme squamous cell carcinoma antiparasitic therapy diclofenac indomethacin oleanolic acid derivative conjugates NF-κB Nrf2 MAPKs PSN-1 cells reactive oxygen species glioblastoma brain tumor extracellular vesicles pancreatic cancer paclitaxel clathrin endocytosis sulforaphane nicotine metalloproteinase-9 gastric cancer cell invasion Arylquin 1 colon cancer tumor progression azelastine oxidative stress autophagy mitotic catastrophe chronic myeloid leukemia imatinib tyrosine kinase ketoconazole P-glycoprotein drug efflux transporter non-small-cell lung cancer cisplatin resistance aldehyde dehydrogenase isothiocyanates disulfiram epithelial to mesenchymal transition aminopeptidase N acetamidophenones Schiff bases semicarbazones thiosemicarbazones inhibition of proliferation
ISBN	3-0365-5927-2
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Record Nr.	UNINA-9910639990003321