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Hereditary Hemorrhagic Telangiectasia : Recent Advances and Future Challenges
| Hereditary Hemorrhagic Telangiectasia : Recent Advances and Future Challenges |
| Autore | Mager Hans-Jurgen |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (228 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
hereditary hemorrhagic telangiectasia
rare diseases telangiectasis transforming growth factor-beta (TGF-β) Smad pathway gastrointestinal bleeding epistaxis nosebleeds tacrolimus nasal ointment genetic disease rare disease hereditary hemorrhagic telangiectasia (HHT) telangiectases mechanical damage sun-induced trauma vascular malformations Endoglin activin-receptor-like kinase 1 Hereditary Hemorrhagic Telangiectasia antithrombotic therapy anticoagulants antiplatelets bleeding safety HHT ALK1 endoglin raloxifene bazedoxifene tranexamic acid propranolol FK506 etamsylate N-acetylcysteine pulmonary arteriovenous malformations transcatheter embolotherapy screening guidelines Hereditary hemorrhagic telangiectasia pediatrics genotype–phenotype correlation arteriovenous malformation ENG ACVRL1 SMAD4 microRNA biomarker plasma arteriovenous malformations (AVMs) angiogenesis activin receptor-like kinase 1 (ALK1) transforming growth factor beta (TGF-β) bone morphogenetic protein (BMP) propranolol gel epistaxis severity score nasal endoscopy antiangiogenic properties non-coding RNAs microRNAs long non-coding RNAs biomarkers endothelial cells hereditary hemorrhagic telangiectasia (HHT), second-hit arteriovenous malformation (AVM) Smad4 inflammation shear stress vascular injury somatic mutation cell adhesion vascular endothelial growth factor (VEGF) telangiectasia hereditary hemorrhagic survival life expectancy pulmonary arteriovenous malformation contrast enhanced magnetic resonance angiography liver MRI ultrasound AVM bevacizumab Osler–Weber–Rendu hereditary hemorrhagic telangiectasia/HHT/osler’s disease cerebral ischemic lesions catheter based embolization therapy |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Hereditary Hemorrhagic Telangiectasia |
| Record Nr. | UNINA-9910557578003321 |
Mager Hans-Jurgen
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Kidney Inflammation, Injury and Regeneration
| Kidney Inflammation, Injury and Regeneration |
| Autore | Koch Benjamin |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (496 p.) |
| Soggetto non controllato |
microRNAs
transcription ischemia/reperfusion injury DSS-colitis kidney inflammation therapeutics targets CXCL13 glomerulus interleukin-6 rhabdomyolysis IgA nephropathy CREB Regulated Transcriptional Coactivators (CRTC) slit diaphragm injury xanthine oxidase Salt Inducible Kinase (SIK) acute and chronic kidney disease therapeutic target KIT-IgA score G-protein-coupled bile acid receptor (TGR5) lysophosphatidic acid glomerular injury IL-18 mesenchymal stem cells Taiwan acute kidney injury renal ischemia-reperfusion long non-coding RNA fibrosis acute kidney failure diabetic kidney diseases chronic kidney disease lncRNA LPS-binding protein endotoxemia-induced oliguric kidney injury dapagliflozin cPLA2 and COX-2 NLRP3 inflammasome CmklR1 haem chronic kidney injury omega-3 fatty acid noninvasive inflammation regulated necrosis GLP-1 receptor agonists miRNA AKI SGLT2 inhibitors diabetic kidney disease extracellular vesicles podocin type IV collagen epithelial cells nephrin 2-kidney-1-clip renal fibrosis papilla diagnostics necrosis non-coding RNAs podocyte Thy1.1 nephritis KIT assay oxidative stress conditioned medium C-reactive protein pericyte myofibroblast Nuclear Factor kappa-light-chain-enhancer of activated B cells (NF-?B) endotoxemia modifier gene polymorphism renal stem cells kidney polyploidization Class IIa Histone Deacetylases (HDAC) 2k1c molecular signaling proximal tubule arachidonic acid empagliflozin tubular injury signaling cascade signal transduction inflammatory maker niches biomarkers renal progenitors type V collagen cyclooxygenase focal segmental glomerulosclerosis inflammatory bowel disease (IBD) chronic kidney disease (CKD) allograft rejection renovascular hypertension genotype molecular mechanisms ROS prediction glomerular filtration barrier (GFB) alport syndrome scattered tubular cells long non-coding RNAs renal inflammation lysophosphatidic acid receptor cAMP Regulatory Element Binding Protein (CREB) Farnesiferol B differentiation mesenchymal stromal cells modified-MSCs kidney transplantation polyunsaturated fatty acids apoptosis type I collagen diabetes mellitus natural products lipoxygenase stem cell T cell-mediated rejection exosomes renal injury obese kidney fibrosis kidney injury cytotoxicity mesenchymal stem cell pigment nephropathy mesodermal stem cell ischemia-reperfusion cytochrome P450 renal cell carcinoma hematuria B-cell attracting chemokine microRNA chemerin glomerular basement membrane glomerular damage renal tubular cells kidney proximal tubule exosome hypertension diabetic nephropathy |
| ISBN | 3-03928-539-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404091203321 |
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Koch Benjamin
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mechanisms and Novel Therapeutic Approaches for Gynecologic Cancer
| Mechanisms and Novel Therapeutic Approaches for Gynecologic Cancer |
| Autore | Nakayama Naomi |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (258 p.) |
| Soggetto topico | Public health & preventive medicine |
| Soggetto non controllato |
nucleus accumbens-associated protein 1 (NAC1)
BEN (BANP, E5R and NAC1) domain sequence-specific DNA-binding protein solution NMR structure isothermal titration calorimetry (ITC) human cytomegalovirus ovarian cancer cancer progression inflammation immunosuppression endometrial carcinoma immune micro-environment immune checkpoints inhibitors microsatellite instability mismatch repair deficiency platelet-activating factor acetylhydrolase (PAF-AH PLA2G7) BRCA1 mutant ovarian cancer Wnt signaling pGSK3β β-catenin prognosis vulvar melanoma vaginal melanoma targeted therapy gynecological cancer melanoma treatment gene ontology epithelial ovarian cancers borderline ovarian tumors differentially expressed genes aryl hydrocarbon receptor epithelial-mesenchymal transition integrative analysis testin p16 protein cervical cancer cervical neoplasia immunohistochemistry chimeric antigen receptor CD44 adoptive immunotherapy NK cells epithelial ovarian cancer DNA damage response somatic mutation clear cell carcinoma endometrioid endometrial cancer DNA mismatch repair (MMR) MMR deficient (dMMR) long-term survival exosome miRNA biomarkers liquid biopsy interventional radiotherapy vaginal-cuff brachytherapy HDR brachytherapy in vivo dosimetry endometrial cancer biological planning drug repurposing non-coding RNAs nanocarriers anti-angiogenic therapy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580209103321 |
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Nakayama Naomi
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Mechanisms and New Therapeutic Targets in Epithelial to Mesenchymal Transition (EMT) and Fibrosis
| Molecular Mechanisms and New Therapeutic Targets in Epithelial to Mesenchymal Transition (EMT) and Fibrosis |
| Autore | Battistelli Cecilia |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (219 p.) |
| Soggetto topico |
Science: general issues
Pharmacology |
| Soggetto non controllato |
natural compound
EMT fibrosis epigenetics non-coding RNAs therapeutic targets |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Molecular Mechanisms and New Therapeutic Targets in Epithelial to Mesenchymal Transition |
| Record Nr. | UNINA-9910557256503321 |
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Battistelli Cecilia
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Post-transcriptional Regulation through Long Noncoding RNAs (lncRNAs)
| Post-transcriptional Regulation through Long Noncoding RNAs (lncRNAs) |
| Autore | Ladomery Michael |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (156 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
long non-coding RNA 1
RNA binding protein 2 post-transcriptional regulation long non-coding RNA mRNA stability RNA binding protein microRNA gene expression long noncoding RNA target mimicry alternative splicing protein re-localization translation promotion post-translational modification double-stranded RNA (dsRNA) innate immunity repetitive DNA elements (RE) antisense transcript non-coding RNAs long non-coding RNAs ncRNAs translation cancer lncRNA post-transcription RNA-binding ribonucleoprotein RNAi interactome prediction database CLIP splicing factors miRNAs lncRNAs ceRNAs mTOR pathway |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Post-transcriptional Regulation through Long Noncoding RNAs |
| Record Nr. | UNINA-9910557367803321 |
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Ladomery Michael
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Role of Natural Bioactive Compounds in the Rise and Fall of Cancers : Volume 2
| Role of Natural Bioactive Compounds in the Rise and Fall of Cancers : Volume 2 |
| Autore | Luparello Claudio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (318 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
berberine
signaling pathways oncogenic cascades TRAIL microRNAs cancer therapy colon cancer cells ethanol Nrf2 HO-1 ER stress autophagy MMPs formononetin cancer preclinical models cell signaling angiogenesis nobiletin colorectal cancer chemoprevention bioactivities experimental therapeutics HDAC multiple myeloma oleacein breast cancer persistent organic pollutants breast cancer risk breast cancer prognostic systematic review carrageenan invasion metastasis RacGAP1 radiotherapy marine sponge natural product anticancer drug oral cancer inhibition phytochemicals small organic agents Piper eriopodon, alkenylphenols human cancer cells cell death apoptosis caspase-independent cell death XIAP antagonists XIAP-BIR3 domain Calocedrus formosana lung cancer yatein cell-cycle arrest xenograft isorhamnetin G2/M arrest ROS AMPK pancreatic cancer epigallocatechin-3-gallate (EGCG) gemcitabine glycolysis phosphofructokinase natural polyphenols anticancer activities molecular mechanisms Streptomyces mangrove anti-proliferative colon cancer epithelial mesenchymal transition inflammation malignant cancer natural anti-inflammatory compounds pro-resolving lipids anticancer drugs flavonoids natural compounds Xenopus laevis AOM/DSS model melanoma cells nicotine α9-nAChR PD-L1 STAT3 gigantol AKT JAK/STAT cancer stem cell tumor maintenance tumor density proteomics honokiol anticancer mechanism signalling pathway uterine sarcoma fucoidan isobolography colchicine alkaloid mesoporous silica nanoparticles targeted delivery system PD-1 immune checkpoint inhibitor and cancer immunotherapy glucose transport drugs innate immunity β-glucans nutrition immunotherapy estrogen estrogen receptor alpha polyphenols daidzein daidzein metabolites paclitaxel breast cancer cells obesity renin-angiotensin system eicosapentaenoic acid adipocyte inflammation olive leaf extract oleuropein Seahorse analysis cancer metabolism glycolytic markers Malva pseudolavatera Webb & Berthel acute myeloid leukemia reactive oxygen species brain cancer gliomas schwannomas malignant tumors of the peripheral nerve sheath (MPNST) neurofibromas bioavailability nanoparticle-based delivery systems natural bioactive compound gallic acid EGFR signaling p53 EGCG non-coding RNAs anti-cancer drug NSCLC EGFR TKI FASN inhibitors resistance |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Role of Natural Bioactive Compounds in the Rise and Fall of Cancers |
| Record Nr. | UNINA-9910557476303321 |
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Luparello Claudio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Towards New Promising Discoveries for Lung Cancer Patients: A Selection of Papers from the First Joint Meeting on Lung Cancer of the FHU OncoAge (Nice, France) and the MD Anderson Cancer Center (Houston, TX, USA)
| Towards New Promising Discoveries for Lung Cancer Patients: A Selection of Papers from the First Joint Meeting on Lung Cancer of the FHU OncoAge (Nice, France) and the MD Anderson Cancer Center (Houston, TX, USA) |
| Autore | Hofman Paul |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (230 p.) |
| Soggetto non controllato |
microRNAs
multiplexed screening education non-smoker image analysis artificial intelligence research lung cancer spatial analysis optimization fluorescence geriatric assessment geriatric interventions TNBC liquid biopsy non-small cell lung cancer integrated approaches well-being hormone-like action EGFR mutations reversal of EMT tumor plasticity immune profiling macrophage multiplexed methodologies targeted treatment techniques immune-oncology bioinformatics MALAT1 long non-coding RNAs CD8 T Cells personal medicine EGFR TKIs lncRNA hormones elderly interleukin-1? and immunometabolism chromogenic xenograft metastasis PD-1/PD-L1 checkpoint blockade immunotherapy molecular cancer tissues digital NSCLC immune blockade lung adenocarcinoma circulating tumor cells brightfield non-coding RNAs older adults cancer tumor microenvironment aging rational therapy |
| ISBN | 3-03921-452-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Towards New Promising Discoveries for Lung Cancer Patients |
| Record Nr. | UNINA-9910367760103321 |
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Hofman Paul
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Transcriptome and Genome Analyses Applied to Aquaculture Research
| Transcriptome and Genome Analyses Applied to Aquaculture Research |
| Autore | Pereiro Patricia |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (554 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Fisheries & related industries |
| Soggetto non controllato |
RNA-Seq
lncRNAs Dicentrarchus labrax viral infection nodavirus immune response fish T lymphocytes infection malnutrition inflammation aquaculture histopathology immunohistochemistry enteromyxosis Philasterides dicentrarchi turbot transcriptomics Chinese mitten crab Eriocheir sinensis transportome transporters salinity osmoregulation transcriptome meta-analysis gills short pentraxins c-reactive protein zebrafish transcript expression antiviral SVCV rag1 mutants skin mucosal immunity hypoxia hypo-metabolic state growth swimming performance metabolic landmarks muscle transcriptome glycolysis lipid metabolism protein turnover gilthead sea bream hepatopancreas necrosis disease metatranscriptomics sequencing hepatopancreatic flora teleost B cells single cell transcriptomics immunoglobulins immune markers transcription factors long non-coding RNAs hepatic transcript expression salmon microarray omega-6/omega-3 ratio nutrigenomics fatty acids liver muscle Misgurnus anguillicaudatus sexual size dimorphism polyploid size dimorphism comparative transcriptome gene expression edible red sea urchin Loxechinus albus RNA-seq reference transcriptome Chinese soft-shelled turtle Aeromonas hydrophila hemorrhagic sepsis molecular immunopathogenesis tripartite motif proteins B30.2 domain antiviral immunity Ctenopharyngodon idella grass carp reovirus metamorphosis brain RNA sequencing intermuscular bone development Megalobrama amblycephala Oreochromis niloticus histological structure Atlantic salmon smoltification genome mRNAs miRNAs sox family genes Pelodiscus sinensis estradiol pseudo-female sex-related heterosis heterobeltiosis environment transgressive genes conserved miRNA high-throughput sequencing lumpfish novel miRNA RT-qPCR heat shock protein co-chaperon network salinity-alkalinity adaptation molecular evolution Lateolabrax maculatus genomics stress response HPI-axis neuroendocrine-immune interaction common carp poly-unsaturated fatty acid fatty acid elongase association study genomic selection bulked segregant analysis SNP association analysis joint effect seawater adaptation microRNAs small-RNA sequencing microarray transcriptome European seabass chronic inflammation opioid receptors immune status whole-transcriptome sequencing sex differentiation non-coding RNAs ceRNA red cusk-eel thermal stress liver transcriptome oxidative damage protein folding hepatic enzymes |
| ISBN | 3-0365-5921-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910637793503321 |
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Pereiro Patricia
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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