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Long-Term Consequences of Adolescent Drug Use: Evidence from Pre-Clinical and Clinical Models
| Long-Term Consequences of Adolescent Drug Use: Evidence from Pre-Clinical and Clinical Models |
| Autore | Torregrossa Mary |
| Pubbl/distr/stampa | Frontiers Media SA, 2018 |
| Descrizione fisica | 1 online resource (201 p.) |
| Collana | Frontiers Research Topics |
| Soggetto topico | Medicine |
| Soggetto non controllato |
alcohol
cannabinoid cocaine juvenile ketamine methamphetamine nicotine prefrontal cortex sex differences stress |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Long-Term Consequences of Adolescent Drug Use |
| Record Nr. | UNINA-9910346746503321 |
Torregrossa Mary
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| Frontiers Media SA, 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Compounds and Cancer 2020
| Marine Compounds and Cancer 2020 |
| Autore | Honecker Friedemann |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (480 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
12-deacetyl-12-epi-scalaradial
3-alkylpyridinium polymers A375 and HeLa cell lines A549 cells ABC transporter actinomycin AD0157 adriamycin resistance Aeroplysinin Akt angiogenesis angiogenesis inhibitor ansamycins anthranilic acid anti-angiogenesis anti-angiogenic anti-cancer anti-metastatic activity anti-proliferation anti-proliferative antiangiogenesis antiangiogenic antibacterial Antibody Drug Conjugates (ADCs) anticancer anticancer activity anticancer agent anticancer immunity anticarcinogenic anticoagulant anticoagulation antifouling Antimicrobial peptide (AMP) antioxidant antiproliferative antiproliferative activity antitumor antitumor activities antitumoral antitumour AP-1 apoptosis apoptosis-inducing activity approved antitumor agents araguspongine C arrest of cell cycle Aspergillus autophagy autophagy inducers autophagy inhibitors azoxymethane BCRP/ABCG2 BEL-7402 cell benzo[a]pyrene bioactive natural product bioanalysis bis (2,3-dibromo-4,5-dihydroxy-phenyl)-methane (BDDPM) bonnethead shark breast cancer breast cancer cells Brevianamide brominated indoles bromophenol buccal gland c-JUN c-Met C15 acetogenins camptothecin cancer Cancer cancer genes cancer preventive cancer progression Cantabrian Sea-derived actinobacteria carbocyclic analogue carcinoembryonic antigen Caribbean sponge carotenoid carotenoids caspase cascade cell adhesion cell adhesion molecules cell cycle cell cycle arrest cell migration cembranoids chemical conjugation chemoprevention chemopreventive chemosensitization chemotherapy chimera CHOP chromatography circulating tumor cells cisplatin clinical trials colorectal cancer cooperative binding cyclin D1 cyclin-dependent kinase CYP1A1 cystatin F cystatin superfamily cytokine release cytoskeleton cytotoxic activity cytotoxicity deep-sea depolymerisation dibromotyrosine dieckol divergolides DNA minor groove binder drug discovery Ecklonia cava elisidepsin EMT endoperoxide endophytic fungus endothelial cells energy stress epigonal organ epithelial-mesenchymal transition ER-stress ET-743 evolution FAK fascaplysin fatty acid 2-hydroxylase fatty acids FAU FBDD fucoidan fucoxanthin fumigaclavine C gemcitabine gene expression glioblastoma gliotoxin glucocorticoid receptor glycosaminoglycans gorgonian Haliclona gracilis HeLa cells heparan sulphate heparanase hepatocellular carcinoma HER2 HIF-1 hippuristanol HSP90 human lung cancer human normal diploid fibroblast (TIG-1 cells) human sarcoma cell line (HT1080 cells) humulane sesquiterpenoids hybridization hydroxylated lipids hypoxia hypoxia-inducible factor-1 IL-6 in vivo model inflammation inhibitor integrin β1 invasion isatin Isofistularin itampolin A jaspine B JNK1/2 Jurkat kalkitoxin kunitz type inhibitor Lampetra morii Leathesia nana Leptogorgia leukemia lipid rafts low molecular weight fucoidan extract low toxic LS-1 lung cancer lung metastasis Lyngbya majuscula macrolide mangrove-derived actinomycete manzamine A MAPK/ERK pathway marangucyclines marine antitumor agents marine biotechnology marine compound marine drug marine drugs marine fungus marine metabolites marine mollusc marine natural products marine organisms marine sponges marine-derived drugs Marthasterias glacialis L. MCP-1 mechanisms of action melanoma membrane permeabilization metastasis microalgae Micromonospora migration mitochondria mitochondria toxin mitochondrial pathway mitochondrial dysfunction molecular docking molecular mechanisms molecular modeling molecular oncology Moorea producens MRP1/ABCC1 multi-drug resistant leukemia multidrug resistance Mycalin A Mycochromenic acid derivative N-Ras n/a nanoparticle naphthopyrones natural marine compounds natural product natural products neuroblastoma-rat sarcoma NF-κB NF-κB signaling nicotine nicotinic acetylcholine receptor non-small cell lung cancer non-small cell lung cancer (NSCLC) non-small cell lung carcinoma nonfunctioning pituitary adenomas novel inhibitor NSCLC Nur77 osteosarcoma oxidative stress oxidative stress P-gp/ABCB1 P2X7 receptor p38 p38/ERK p38α p65 pachastrissamine palmitic acid paulomycins pazopanib PEL Penicillium brevicompactum Penicillium paneum phase I pheochromocytoma and paraganglioma phlorotannins phycocyanin PI3K/Akt plakortide plitidepsin pollution poly(ADP-ribose)-polymerase inhibitor polyoxygenated steroids polyphenols polysaccharides Porifera porifera/sponge preclinical programmed cell death programmed cell death-ligand 1 programmed cell death-ligand 2 proliferation prostate cancer proteasomal degradation proteomic pseudopterosin puupehenones pyrrolidinedione reactive oxygen species RGD motif ribosomal protein genes ROS RPS30 safety Sarcophyton ehrenbergi sea anemone sea cucumbers seaweed secondary metabolites sediment selenium-containing polysaccharide-protein complex Sepia ink polysaccharides shrimp signal transduction sinulariolide sipholenol A small cell lung cancer SNORA62 snoRNA SNU-C5/5-FU soft coral soft tissue sarcoma soft tissue sarcoma sphingosine kinase inhibitor sponge sponges STAT3 Streptomyces sp. SCSIO 11594 synergism synthetic analogues SZ-685C targeted therapy terpenes tetracenomycin X TGF-β signaling Thalassia testudinum thalassiolin B therapeutic compounds Tilapia piscidin 4 (TP4) TNFα Topo I inhibitor topoisomerase trabectedin triterpene glycosides TRPM7 tumor cell line tumor microenvironment tumor-associated macrophages Ulva fasciata uveal melanoma VEGF virtual screening xyloketal B α9-nicotinic acetylcholine receptors (nAChRs) αO-conotoxin GeXIVA β1-integrin λ-carrageenan |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557339303321 |
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Honecker Friedemann
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Method Development and Applications for Reduced-Risk Products in Separation Science
| Method Development and Applications for Reduced-Risk Products in Separation Science |
| Autore | Aldeek Fadi |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (154 p.) |
| Soggetto topico |
Analytical chemistry
Chemistry Research & information: general |
| Soggetto non controllato |
"hidden formaldehyde"
2,4-DNPH derivatization 3-hydroxybenzo[a]pyrene aerosol alkaloids biomarker of exposure chemical characterization compliance marker constituents derivatization dissolution e-cigarette e-liquid electronic cigarette ENDS equivalence formaldehyde formaldehyde-containing hemiacetal/acetal adducts GC-MS HPHC HPHCs human biomonitoring JUUL LC-HRMS LC-MS/MS method development method validation modern oral nicotine products n/a nicotine nicotine degradants nicotine degradation products nicotine dissolution nicotine extraction nicotine pouches nicotine release nicotine-related impurities non-targeted analysis on!® nicotine pouches oral tobacco derived nicotine (OTDN) pouches potentially reduced-risk products product assessment product characterizations propylene glycol reduced-risk products release profile smokeless tobacco product snus urine validation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566466903321 |
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Aldeek Fadi
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Role of Natural Bioactive Compounds in the Rise and Fall of Cancers : Volume 2
| Role of Natural Bioactive Compounds in the Rise and Fall of Cancers : Volume 2 |
| Autore | Luparello Claudio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (318 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
acute myeloid leukemia
adipocyte inflammation AKT AMPK angiogenesis anti-cancer drug anti-proliferative anticancer anticancer activities anticancer drug anticancer drugs AOM/DSS model apoptosis autophagy berberine Berthel bioactivities bioavailability brain cancer breast cancer breast cancer cells breast cancer prognostic breast cancer risk Calocedrus formosana cancer cancer metabolism cancer stem cell cancer therapy carrageenan caspase-independent cell death cell death cell signaling cell-cycle arrest chemoprevention colchicine alkaloid colon cancer colon cancer cells colorectal cancer daidzein daidzein metabolites drugs EGCG EGFR signaling EGFR TKI eicosapentaenoic acid epigallocatechin-3-gallate (EGCG) epithelial mesenchymal transition ER stress estrogen estrogen receptor alpha ethanol experimental therapeutics FASN inhibitors flavonoids formononetin fucoidan G2/M arrest gallic acid gemcitabine gigantol gliomas glucose transport glycolysis glycolytic markers HDAC HO-1 honokiol human cancer cells immunotherapy inflammation innate immunity invasion isobolography isorhamnetin JAK/STAT lung cancer malignant cancer malignant tumors of the peripheral nerve sheath (MPNST) Malva pseudolavatera Webb & mangrove marine sponge mechanism melanoma cells mesoporous silica nanoparticles metastasis microRNAs MMPs molecular mechanisms multiple myeloma n/a nanoparticle-based delivery systems natural anti-inflammatory compounds natural bioactive compound natural compounds natural polyphenols natural product neurofibromas nicotine nobiletin non-coding RNAs Nrf2 NSCLC nutrition obesity oleacein oleuropein olive leaf extract oncogenic cascades oral cancer inhibition p53 paclitaxel pancreatic cancer PD-1 immune checkpoint inhibitor and cancer immunotherapy PD-L1 persistent organic pollutants phosphofructokinase phytochemicals Piper eriopodon, alkenylphenols polyphenols preclinical models pro-resolving lipids proteomics RacGAP1 radiotherapy reactive oxygen species renin-angiotensin system resistance ROS schwannomas Seahorse analysis signaling pathways signalling pathway small organic agents STAT3 Streptomyces systematic review targeted delivery system TRAIL tumor density tumor maintenance uterine sarcoma xenograft Xenopus laevis XIAP antagonists XIAP-BIR3 domain yatein α9-nAChR β-glucans |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Role of Natural Bioactive Compounds in the Rise and Fall of Cancers |
| Record Nr. | UNINA-9910557476303321 |
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Luparello Claudio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Sex, Gender and Substance Use
| Sex, Gender and Substance Use |
| Autore | Greaves Lorraine |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (272 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
abortion
adolescents alcohol alcohol consumption alcohol's harms to others attitudes barriers brief intervention cannabis cannabis use disorder cigarettes client perspectives clinical decision support systems cognitions college campus developmental-relational domestic violence drinking drinking cultures electronic cigarettes facilitators FASD FASD prevention fathers gender gender equality gender equity gender norms gender relations gender roles gender transformative gender-specific approach health promotion homophobic bullying hookah illegal substance use interpersonal violence intervention lifestyle males multi-service program delivery nicotine non-medical prescription opioid use policy polytobacco use pregnancy prevention program evaluation public health randomized controlled trial research scoping review second-hand smoke sex sex differences sex factors sex- and gender-based analysis sexual minorities SGBA SGBA+ sleep disturbance smoke-free home smoking smoking cessation Spain substance abuse substance use substance use prevention technology tobacco waterpipe women young adults |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557799003321 |
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Greaves Lorraine
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression
| Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression |
| Autore | Stefanachi Angela |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (416 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
EGR-1
flavonoid (E)-5-((4-oxo-4H-chromen-3-yl)methyleneamino)-1-phenyl-1H-pyrazole-4-carbonitrile MDA-MB-231 MMP9 TNFα pancreatic ductal adenocarcinoma cyclodextrin inclusion complex phase solubility studies preformulation studies biphenylnicotinamide derivatives dual inhibitor EGFR VEGFR2 ligand-based pharmacophore molecular docking molecular dynamics leukemias doxorubicin inflammation drug delivery tumor targeting elastin-like polypeptide cell penetrating peptide matrix metalloproteinase doxorubicin resistance photosensitizer delivery system PAMAM dendrimer photodynamic therapy cytotoxicity phototoxicity colorectal adenocarcinoma dicarboximides chemical synthesis apoptosis kinases anticancer gene profiling SAR biomarkers colorectal cancer early detection examination liquid biopsy personalized medicine tumor treatment exosomes ctDNA CTC cytotoxic activity pyrazole derivatives MTT assay ADMET analysis single-crystal diffraction FTIR spectroscopy NMR spectroscopy thermogravimetric analysis acute myelogenous leukemia platelets microparticles γδ T cells immunotherapy tumor resistance combination therapy tumor microenvironment immune checkpoint inhibitor neuroblastoma molecular iodine cyclophosphamide xenografts metronomic therapy tamoxifen CYP2D6 MCF-7 Ishikawa cells SERM TNBC uterotrophic α-mangostin poly(amidoamine) dendrimer targeted drug delivery biotin targeting glioblastoma multiforme squamous cell carcinoma antiparasitic therapy diclofenac indomethacin oleanolic acid derivative conjugates NF-κB Nrf2 MAPKs PSN-1 cells reactive oxygen species glioblastoma brain tumor extracellular vesicles pancreatic cancer paclitaxel clathrin endocytosis sulforaphane nicotine metalloproteinase-9 gastric cancer cell invasion Arylquin 1 colon cancer tumor progression azelastine oxidative stress autophagy mitotic catastrophe chronic myeloid leukemia imatinib tyrosine kinase ketoconazole P-glycoprotein drug efflux transporter non-small-cell lung cancer cisplatin resistance aldehyde dehydrogenase isothiocyanates disulfiram epithelial to mesenchymal transition aminopeptidase N acetamidophenones Schiff bases semicarbazones thiosemicarbazones inhibition of proliferation |
| ISBN | 3-0365-5927-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639990003321 |
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Stefanachi Angela
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Clinical Utility of Food Addiction and Eating Addiction
| The Clinical Utility of Food Addiction and Eating Addiction |
| Autore | Cassin Stephanie |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (246 p.) |
| Soggetto topico |
Medicine and Nursing
Surgery |
| Soggetto non controllato |
addiction
addictive behaviors addictive eating adverse childhood experience bariatric surgery binge eating binge-eating disorder biopsychosocial clinical utility clinical vignette clinician cognitive behavioural therapy comorbidity diabetes diet dietary restraint dopamine early life adversity eating addiction eating behavior eating behaviour eating disorder eating disorders epigenetics food food addiction food intake food intake variety health professional hedonic pathway homeostatic pathway metabolic syndrome n/a nicotine non-communicable disease nutrition obesity overconsumption overeating overweight policy posttraumatic stress disorder processed food psychiatric comorbidity psychosocial impairment quality of life stress substance use disorder telephone therapy tobacco use disorder trauma treatment weighing weight gain weight loss Yale Food Addiction Scale |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557450203321 |
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Cassin Stephanie
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Role of PPARs in Disease
| The Role of PPARs in Disease |
| Autore | Wagner Nicole |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (274 p.) |
| Soggetto topico |
Medicine and Nursing
Physiology |
| Soggetto non controllato |
addiction
adipogenesis AKI alcohol Alzheimer's Alzheimer's disease (AD) angiogenesis animal models cancer cellular metabolism cilia CKD cognition coronary artery CYP450 cystogenesis dominant-negative isoform eicosanoids endothelial cells fatty acids fetal programming fibrosis folate growth suppressors human studies hypertrophic adipocytes hypertrophic obesity immortality immune system in vitro adipocytes inflammation inherited metabolic disorders insulin-resistance kidney ligand ligands lipidomics lipids metabolic syndrome metastasis metastasis formation modulators nephron nicotine non-alcoholic fatty liver disease (NAFLD) non-alcoholic steatohepatitis (NASH) nuclear receptors obesity opioids peroxisome proliferator activated receptors peroxisome proliferator-activated receptor peroxisome proliferator-activated receptor-γ coactivator-1α peroxisome proliferator-activated receptors (PPARs) peroxisome-proliferator activated receptors PGC-1α, disease pharmacology PKD PPAR PPARG isoforms PPARG splicing PPARs PPARα proliferation psychostimulants resistance to cell death risk factors RNA sequencing sex Sirtuin1 synthetic agonists therapy toxicology tumor angiogenesis tumor progression vascular vitamin B12 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566482503321 |
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Wagner Nicole
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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