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Antimicrobial Peptides Aka Host Defense Peptides – From Basic Research to Therapy
| Antimicrobial Peptides Aka Host Defense Peptides – From Basic Research to Therapy |
| Autore | Petrlova Jitka |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (226 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
ECP
AMPs infection murine model Gram-negative bacteria LPS host defense peptides monocytes neutrophils neutrophil–monocyte interaction extracellular traps host defense peptide innate immunity NF-κB poly I:C toll-like receptor 3 mucus of Cornu aspersum peptide fraction MW < 10 kDa Escherichia coli NBIMCC 8785 SEM fluorescence and digital assays antibacterial effect oral cavity human cathelicidin antimicrobial peptides immunomodulation oncolytic peptides cancer membrane integrity bulky non-nature amino acid DAMPs drug design antimicrobial peptidomimetic hydrogel-based system hyaluronic acid anti-infective activity skin infections antimicrobial peptide expression intein self-cleavage cecropin-like apolipoprotein E host defense aggregation body fluid AMP interaction network chemical barrier cationic antimicrobial peptides length dependent activity antimicrobial activity hemolysis vesicle leakage solid-state 31P-, 15N- and 19F-NMR β-stranded peptides β-sheets structure and orientation of peptides in membranes |
| ISBN | 3-0365-5820-9 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639991103321 |
Petrlova Jitka
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cellular and Molecular Mechanisms in Pathogenesis of Multiple Sclerosis
| Cellular and Molecular Mechanisms in Pathogenesis of Multiple Sclerosis |
| Autore | Wan Edwin |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (182 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
A971432
autoimmune disease AUY954 bioinformatics CD4+ T cells central memory T cell clonal analyses demyelination disease activity effector memory T cell experimental autoimmune encephalomyelitis experimental autoimmune encephalomyelitis (EAE) gliosis glutamate synaptic dysfunction granulocyte-macrophage colony-stimulating factor histology IDO in utero electroporation inside-out kynurenic acid kynurenine pathway laquinimod lesioned brain lineage lymphocytes memory T cells microglia mitochondria monocytes morphometric analyses multiple sclerosis N-acetylserotonin n/a NAD+, multiple sclerosis neuroinflammation neutrophils NG2-glia NLR oligodendrocytosis outside-in oxidative stress ozanimod pentamidine pro-inflammatory cytokines progenitors quinolinic acid relapsing-remitting experimental autoimmune encephalomyelitis S100B S1P1 S1P5 sphingosine-1-phosphate receptors T lymphocytes tissue-resident T cell top-down proteomics |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557306103321 |
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Wan Edwin
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Circulating Tumor Cells: Finding Rare Events for A Huge Knowledge of Cancer Dissemination
| Circulating Tumor Cells: Finding Rare Events for A Huge Knowledge of Cancer Dissemination |
| Autore | Alix-Panabieres Catherine |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (366 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
abiraterone
ACCEPT androgen receptor AR AR-V7 ARV7 biomarker biomarkers bone marrow breast cancer castration resistant prostate cancer (CRPC) CD133 CellSearch CellSearch® cerebrospinal liquid biopsy chemoradioresistance chromogranin A circulating leukemia cells circulating plasma cells circulating tumor cells circulating tumor cells (CTC) circulating tumor cells (CTCs) circulating tumor DNA circulating tumour cells clinical trials clinical utility colorectal cancer colorectal surgery CTC CTC biology CTC capture technology CTC-based treatment decisions CTC-derived ex vivo models CTC-derived xenografts CTCs ctDNA CTM CTMat ctRNA disseminated tumor cells early breast cancer EasyCount slides emboli enrichment and detection technologies enzalutamide EpCAM enrichment EPISPOT epithelial-mesenchymal transition epithelial-to-mesenchymal transition (EMT) exosome exosomes fibronectin fish flow cytometry FOLFIRINOX gene expression analysis glioma hematological cells hepatocellular carcinoma (HCC) heterogeneity HMB-45 immune checkpoint inhibitors immune system immunofluorescence imaging immunomodulation immunophenotyping in vivo flow cytometry integrin B1 leukocyte-derived extracellular vesicles liquid biopsy liquid surgery locally advanced rectal cancer major histocompatibility complex class I (MHCI) malaria melanoma metastasis metastatic colorectal cancer microbiome microfluidics microsatellite instability miRNA n/a neutrophils NSCLC PD-L1 expression platelets prostate cancer prostate cancer (PCa) RAD23B rovalpituzumab tesirine rVAR2 single-cell analysis SLUG small-cell lung carcinoma solid cancers stem cells synaptophysin targeted therapy thymidylate synthase tumor biomarkers tumor cell dissemination tumor stem cells tumor-initiating cells (TICs) xenograft models |
| ISBN | 3-03928-699-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Circulating Tumor Cells |
| Record Nr. | UNINA-9910404091403321 |
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Alix-Panabieres Catherine
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Neutrophil Extracellular Traps : Mechanisms and Role in Health and Disease
| Neutrophil Extracellular Traps : Mechanisms and Role in Health and Disease |
| Autore | Anders Hans-Joachim |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (212 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
adults
Alzheimer's disease autoantigens autoimmune diseases autoimmunity borrelia brain brain-blood barrier Candida albicans carbon tetrachloride cardiovascular disease cathelicidin central nervous system cerebrospinal fluid chemokines children complement coronavirus cytokines diabetes diseases equine recurrent uveitis farnesol fibrinogen G-CSF head-and-neck cancer hemozoin horse IL-1β infection inflammation innate immunity ischemic stroke liver injury malaria meningitis MERS-CoV metastasis multiple sclerosis myeloperoxidase n/a necroinflammation NETosis NETs neurons neutrophil extracellular trap neutrophil extracellular traps neutrophil extracellular traps (NETs) neutrophil functions neutrophils neutrophils extracellular traps NLRP3 inflammasome obesity ophthalmology periodontitis plasma platelet quorum sensing SARS-CoV-2 thrombosis virus |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Neutrophil Extracellular Traps |
| Record Nr. | UNINA-9910557283903321 |
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Anders Hans-Joachim
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Placental Related Disorders of Pregnancy
| Placental Related Disorders of Pregnancy |
| Autore | Mistry Hiten D |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (378 p.) |
| Soggetto topico |
Medicine
Physiology |
| Soggetto non controllato |
low-dose aspirin
preeclampsia placenta eicosanoids sphingolipids thromboxane prostacyclin isoprostanes neutrophils protease-activated receptor 1 cold shock protein intrauterine growth restriction placentation apoptosis NF-κB hypertension in pregnancy angiogenesis endothelial function oxidative stress antioxidants post-maturity senescence pre-eclampsia renin-angiotensin system megalin proton pump inhibitors telomere shortening prenatal depression sex differences flow culture system explant culture under flow placental insufficiency SPINT2/HAI-2 foetal growth restriction small for gestational age placentome pregnancy nutrient restriction gene expression transcriptome spontaneous preterm birth bioenergetic metabolism interactome fetal sex disparity CD24 cytotrophoblast syncytiotrophoblast immunohistochemistry quantitative polymerase chain reaction (qPCR) immune tolerance inflammation cytokines adipokines antimicrobial peptides metabolic stress IGF-I insulin lactotroph hormones decidual reaction fetal membranes placental hormones primates uterine spiral artery uterine NK cell chorionic somatomammotropin blood flow nutrient uptake uterus ERAP2 trophoblast cells RNA sequencing differentially expressed genes congenital heart disease hand1 vascular development intrahepatic cholestasis of pregnancy human placenta bile acids transporters pregnancy complications metabolism glycolysis mitochondrial respiration placental metabolism trophoblast glycolysis trophoblast mitochondrial respiration sexual dimorphism Interleukin-15 CD122 natural killer cells macrophages trophoblast Irisin TRPV6 calcium transport skeletal dysplasia serine proteases subunit assembly transient receptor potential antioxidant capacity decidua fetal growth restriction KEAP1 NRF2 |
| ISBN | 3-0365-5899-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639995303321 |
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Mistry Hiten D
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Platelets and Immune Responses during Thromboinflammation
| Platelets and Immune Responses during Thromboinflammation |
| Autore | Schattner Mirta |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 online resource (169 p.) |
| Soggetto topico |
Immunology
Medicine and Nursing |
| Soggetto non controllato |
cancer
endothelial cells inflammation neutrophils platelets sepsis thromboinflammation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557767203321 |
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Schattner Mirta
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Polyamine Metabolism in Disease and Polyamine-Targeted Therapies / Tracy Murray-Stewart
| Polyamine Metabolism in Disease and Polyamine-Targeted Therapies / Tracy Murray-Stewart |
| Autore | Murray-Stewart Tracy |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (240 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
protein synthesis in cancer
neuroblastoma epigenetics Drosophila imaginal discs pneumococcal pneumonia transgenic mice spermidine/spermine N1-acetyl transferase ?-difluoromethylornithine MYC skeletal muscle protein expression curcumin colorectal cancer autophagy human embryonic kidney 293 (HEK293) melanoma tumor immunity Snyder-Robinson Syndrome Streptococcus pneumoniae B-lymphocytes autoimmunity spermine oxidase cell differentiation diferuloylmethane immunity antizyme transgenic mouse polyamine hirsutism chemoprevention CRISPR transglutaminase polyamine analogs NF-?B spermine synthase atrophy aging oxidative stress mast cells African sleeping sickness pancreatic ductal adenocarcinoma eflornithine carcinogenesis ornithine decarboxylase polyamine transport inhibitor putrescine neutrophils spermidine untranslated region spermine polyphenol M2 macrophages polyamine transport system metabolism difluoromethylorthinine DFMO antizyme inhibitors capsule polyamine transport eosinophils MCF-7 cells difluoromethylornithine polyamine metabolism mutant BRAF polyamines cadaverine proteomics airway smooth muscle cells breast cancer X-linked intellectual disability complementation T-lymphocytes bis(ethyl)polyamine analogs antizyme 1 cancer osteosarcoma |
| ISBN |
9783039211531
3039211536 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367757003321 |
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Murray-Stewart Tracy
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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State-of-Art in Innate Immunity
| State-of-Art in Innate Immunity |
| Autore | Fischer Silvia |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (188 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
AIM2
albumin angiogenesis apoptosis ASC autoinflammation bacteria cancer caspase caspase-1 caspase-3 caspase-7 caspase-8 cell culture chronic liver diseases COVID-19 crosstalk cytokines cytomegalovirus DAMP Drosophila suzukii endothelial cells endothelin receptor extracellular RNA extracellular traps gamma delta T cells hemocytes hepatic non-parenchymal cells HMGB1 infection inflammasome inflammation inflammatory cell death innate immunity interleukin-1β IRF1 ischemia macrophage polarization macrophages MLKL n/a necroptosis NETs neutrophil extracellular traps neutrophils NLR NLRP3 nociceptor PANoptosis PANoptosome plasmatocytes plasticity proliferation proteasomopathies proteinopathies proteostasis Pyrin pyroptosis RAGE redundancy repurposing ribosomopathies RIPK1 RIPK3 SIRT1 SMOC1 thrombin TLR4 toll-like receptors type I interferons ZBP1 α7-nicotinic acetylcholine receptor γδ T cells |
| ISBN | 3-0365-5324-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910619465003321 |
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Fischer Silvia
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Symmetry Breaking in Cells and Tissues
| Symmetry Breaking in Cells and Tissues |
| Autore | Goryachev Andrew |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (322 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
actin dynamics
actin polymerization actin waves activator-inhibitor models activator-substrate mechanism actomyosin apoptotic extrusion bifurcation theory biphasic responses bottom-up synthetic biology Cdc42 Cdc42 oscillations cell fusion cell motility cell polarity cell polarization cellular memory chemotaxis clustering contractility cortexillin CRY2-CIBN curved proteins cytokinesis cytoplasmic flow cytoskeleton developmental transitions Dictyostelium diffusion direction sensing dynamic instability fission yeast fission yeast Schizosaccharomyces pombe GTPase activating protein (GAP) intracellular polarization intracellular waves mass conservation mass-conserved models mathematical model membrane and cortical tension modelling modularity motor proteins myosin n/a natural variation network evolution neutrality neutrophils nonlinear waves oncogenic extrusion optogenetics partial differential equations pattern formation phase separation phase-space analysis podosomes polarity polarization positive feedback prions pseudopod Ras activation reaction-diffusion reaction-diffusion model Saccharomyces cerevisiae self-organization sensitivity analysis signal transduction small GTPases spatial localization stress symmetry breaking symmetry-breaking |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557440703321 |
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Goryachev Andrew
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Role of Extracellular Matrix in Cancer Development and Progression
| The Role of Extracellular Matrix in Cancer Development and Progression |
| Autore | Tzanakakis George |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (182 p.) |
| Soggetto topico | Research and information: general |
| Soggetto non controllato |
angiogenesis
BCC biomarker biomarkers breast cancer cancer cancer cell growth CD44 EGCG elastin epithelial-to-mesenchymal transition estrogen receptors extracellular matrix extracellular vesicles fibrosis heparan sulfate hyaluronan immune cell modulation invasion lumican macrophages malignant pleural mesothelioma matrix metalloproteinases metastasis MMP MMP-2 motility n/a neutrophil extracellular trap neutrophils pancreatic ductal adenocarcinoma pleural effusion prognosis proteoglycan proteoglycans RHAMM ribosomal protein SA signal transduction sulfated hyaluronan syndecan-4 syndecans TIMP tongue carcinoma tumor progression wound repair |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566470803321 |
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Tzanakakis George
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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