Antimicrobial Peptides Aka Host Defense Peptides – From Basic Research to Therapy |
Autore | Petrlova Jitka |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (226 p.) |
Soggetto topico |
Research & information: general
Chemistry |
Soggetto non controllato |
ECP
AMPs infection murine model Gram-negative bacteria LPS host defense peptides monocytes neutrophils neutrophil–monocyte interaction extracellular traps host defense peptide innate immunity NF-κB poly I:C toll-like receptor 3 mucus of Cornu aspersum peptide fraction MW < 10 kDa Escherichia coli NBIMCC 8785 SEM fluorescence and digital assays antibacterial effect oral cavity human cathelicidin antimicrobial peptides immunomodulation oncolytic peptides cancer membrane integrity bulky non-nature amino acid DAMPs drug design antimicrobial peptidomimetic hydrogel-based system hyaluronic acid anti-infective activity skin infections antimicrobial peptide expression intein self-cleavage cecropin-like apolipoprotein E host defense aggregation body fluid AMP interaction network chemical barrier cationic antimicrobial peptides length dependent activity antimicrobial activity hemolysis vesicle leakage solid-state 31P-, 15N- and 19F-NMR β-stranded peptides β-sheets structure and orientation of peptides in membranes |
ISBN | 3-0365-5820-9 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910639991103321 |
Petrlova Jitka | ||
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Cellular and Molecular Mechanisms in Pathogenesis of Multiple Sclerosis |
Autore | Wan Edwin |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (182 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
neutrophils
lymphocytes NLR multiple sclerosis disease activity inside-out outside-in oligodendrocytosis demyelination gliosis histology top-down proteomics bioinformatics mitochondria CD4+ T cells memory T cells autoimmune disease effector memory T cell central memory T cell tissue-resident T cell experimental autoimmune encephalomyelitis monocytes granulocyte-macrophage colony-stimulating factor S100B relapsing-remitting experimental autoimmune encephalomyelitis pentamidine NG2-glia progenitors lineage in utero electroporation morphometric analyses clonal analyses lesioned brain sphingosine-1-phosphate receptors glutamate synaptic dysfunction microglia T lymphocytes experimental autoimmune encephalomyelitis (EAE) pro-inflammatory cytokines neuroinflammation ozanimod AUY954 A971432 S1P1 S1P5 kynurenine pathway kynurenic acid oxidative stress quinolinic acid N-acetylserotonin IDO NAD+, multiple sclerosis laquinimod |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557306103321 |
Wan Edwin | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Circulating Tumor Cells: Finding Rare Events for A Huge Knowledge of Cancer Dissemination |
Autore | Alix-Panabieres Catherine |
Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (366 p.) |
Soggetto non controllato |
FOLFIRINOX
immunofluorescence imaging AR-V7 circulating tumour cells chemoradioresistance CTC-based treatment decisions rVAR2 immunophenotyping immune system CellSearch® flow cytometry clinical trials circulating tumor DNA synaptophysin stem cells colorectal cancer melanoma CTC biology platelets AR CTC capture technology castration resistant prostate cancer (CRPC) PD-L1 expression rovalpituzumab tesirine HMB-45 thymidylate synthase ctDNA tumor cell dissemination solid cancers metastasis locally advanced rectal cancer miRNA epithelial-to-mesenchymal transition (EMT) NSCLC tumor biomarkers tumor stem cells circulating tumor cells major histocompatibility complex class I (MHCI) bone marrow heterogeneity cerebrospinal liquid biopsy fish glioma in vivo flow cytometry colorectal surgery CellSearch single-cell analysis disseminated tumor cells EasyCount slides microsatellite instability circulating plasma cells circulating leukemia cells ARV7 SLUG androgen receptor metastatic colorectal cancer leukocyte-derived extracellular vesicles prostate cancer (PCa) neutrophils liquid biopsy enzalutamide CD133 enrichment and detection technologies biomarkers immune checkpoint inhibitors biomarker RAD23B microbiome integrin B1 ACCEPT emboli small-cell lung carcinoma EPISPOT microfluidics early breast cancer circulating tumor cells (CTC) tumor-initiating cells (TICs) immunomodulation xenograft models CTC-derived xenografts malaria circulating tumor cells (CTCs) clinical utility exosomes liquid surgery ctRNA CTCs epithelial-mesenchymal transition targeted therapy hematological cells gene expression analysis hepatocellular carcinoma (HCC) breast cancer EpCAM enrichment prostate cancer CTC abiraterone fibronectin CTC-derived ex vivo models CTMat chromogranin A CTM exosome |
ISBN | 3-03928-699-4 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Circulating Tumor Cells |
Record Nr. | UNINA-9910404091403321 |
Alix-Panabieres Catherine | ||
MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Neutrophil Extracellular Traps : Mechanisms and Role in Health and Disease |
Autore | Anders Hans-Joachim |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (212 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
head-and-neck cancer
metastasis neutrophils NETs NETosis innate immunity G-CSF neutrophils extracellular traps ophthalmology diseases neutrophil extracellular traps (NETs) Alzheimer's disease multiple sclerosis ischemic stroke meningitis central nervous system brain neurons brain-blood barrier equine recurrent uveitis horse cathelicidin neutrophil extracellular traps Candida albicans quorum sensing farnesol cerebrospinal fluid adults children infection chemokines cytokines borrelia virus hemozoin plasma fibrinogen platelet malaria NLRP3 inflammasome IL-1β cardiovascular disease inflammation diabetes obesity liver injury neutrophil extracellular trap myeloperoxidase carbon tetrachloride autoimmunity autoimmune diseases autoantigens SARS-CoV-2 coronavirus complement thrombosis MERS-CoV necroinflammation periodontitis neutrophil functions |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Neutrophil Extracellular Traps |
Record Nr. | UNINA-9910557283903321 |
Anders Hans-Joachim | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Placental Related Disorders of Pregnancy |
Autore | Mistry Hiten D |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (378 p.) |
Soggetto topico |
Medicine
Physiology |
Soggetto non controllato |
low-dose aspirin
preeclampsia placenta eicosanoids sphingolipids thromboxane prostacyclin isoprostanes neutrophils protease-activated receptor 1 cold shock protein intrauterine growth restriction placentation apoptosis NF-κB hypertension in pregnancy angiogenesis endothelial function oxidative stress antioxidants post-maturity senescence pre-eclampsia renin-angiotensin system megalin proton pump inhibitors telomere shortening prenatal depression sex differences flow culture system explant culture under flow placental insufficiency SPINT2/HAI-2 foetal growth restriction small for gestational age placentome pregnancy nutrient restriction gene expression transcriptome spontaneous preterm birth bioenergetic metabolism interactome fetal sex disparity CD24 cytotrophoblast syncytiotrophoblast immunohistochemistry quantitative polymerase chain reaction (qPCR) immune tolerance inflammation cytokines adipokines antimicrobial peptides metabolic stress IGF-I insulin lactotroph hormones decidual reaction fetal membranes placental hormones primates uterine spiral artery uterine NK cell chorionic somatomammotropin blood flow nutrient uptake uterus ERAP2 trophoblast cells RNA sequencing differentially expressed genes congenital heart disease hand1 vascular development intrahepatic cholestasis of pregnancy human placenta bile acids transporters pregnancy complications metabolism glycolysis mitochondrial respiration placental metabolism trophoblast glycolysis trophoblast mitochondrial respiration sexual dimorphism Interleukin-15 CD122 natural killer cells macrophages trophoblast Irisin TRPV6 calcium transport skeletal dysplasia serine proteases subunit assembly transient receptor potential antioxidant capacity decidua fetal growth restriction KEAP1 NRF2 |
ISBN | 3-0365-5899-3 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910639995303321 |
Mistry Hiten D | ||
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Platelets and Immune Responses during Thromboinflammation |
Autore | Schattner Mirta |
Pubbl/distr/stampa | Frontiers Media SA, 2020 |
Descrizione fisica | 1 electronic resource (169 p.) |
Soggetto topico |
Medicine
Immunology |
Soggetto non controllato |
platelets
thromboinflammation neutrophils endothelial cells inflammation sepsis cancer |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557767203321 |
Schattner Mirta | ||
Frontiers Media SA, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Polyamine Metabolism in Disease and Polyamine-Targeted Therapies |
Autore | Murray-Stewart Tracy |
Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
Descrizione fisica | 1 electronic resource (240 p.) |
Soggetto non controllato |
protein synthesis in cancer
neuroblastoma epigenetics Drosophila imaginal discs pneumococcal pneumonia transgenic mice spermidine/spermine N1-acetyl transferase ?-difluoromethylornithine MYC skeletal muscle protein expression curcumin colorectal cancer autophagy human embryonic kidney 293 (HEK293) melanoma tumor immunity Snyder-Robinson Syndrome Streptococcus pneumoniae B-lymphocytes autoimmunity spermine oxidase cell differentiation diferuloylmethane immunity antizyme transgenic mouse polyamine hirsutism chemoprevention CRISPR transglutaminase polyamine analogs NF-?B spermine synthase atrophy aging oxidative stress mast cells African sleeping sickness pancreatic ductal adenocarcinoma eflornithine carcinogenesis ornithine decarboxylase polyamine transport inhibitor putrescine neutrophils spermidine untranslated region spermine polyphenol M2 macrophages polyamine transport system metabolism difluoromethylorthinine DFMO antizyme inhibitors capsule polyamine transport eosinophils MCF-7 cells difluoromethylornithine polyamine metabolism mutant BRAF polyamines cadaverine proteomics airway smooth muscle cells breast cancer X-linked intellectual disability complementation T-lymphocytes bis(ethyl)polyamine analogs antizyme 1 cancer osteosarcoma |
ISBN | 3-03921-153-6 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910367757003321 |
Murray-Stewart Tracy | ||
MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
State-of-Art in Innate Immunity |
Autore | Fischer Silvia |
Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (188 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
inflammation
type I interferons interleukin-1β crosstalk hepatic non-parenchymal cells albumin chronic liver diseases bacteria cytomegalovirus endothelin receptor repurposing cell culture Drosophila suzukii hemocytes plasmatocytes extracellular traps HMGB1 RAGE TLR4 DAMP SIRT1 α7-nicotinic acetylcholine receptor nociceptor cancer COVID-19 proteostasis autoinflammation ribosomopathies proteinopathies proteasomopathies extracellular RNA cytokines macrophages endothelial cells toll-like receptors angiogenesis γδ T cells gamma delta T cells proliferation macrophage polarization neutrophils neutrophil extracellular traps NETs ischemia PANoptosis PANoptosome pyroptosis apoptosis necroptosis inflammatory cell death inflammasome innate immunity infection NLR caspase IRF1 ZBP1 RIPK1 RIPK3 MLKL NLRP3 AIM2 Pyrin caspase-1 ASC caspase-8 caspase-3 caspase-7 plasticity redundancy SMOC1 thrombin |
ISBN | 3-0365-5324-X |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910619465003321 |
Fischer Silvia | ||
MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Symmetry Breaking in Cells and Tissues |
Autore | Goryachev Andrew |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
Descrizione fisica | 1 electronic resource (322 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences |
Soggetto non controllato |
actin waves
curved proteins dynamic instability podosomes diffusion cell polarity Cdc42 stress cellular memory phase separation prions apoptotic extrusion oncogenic extrusion contractility actomyosin bottom-up synthetic biology motor proteins pattern formation self-organization cell motility signal transduction actin dynamics intracellular waves polarization direction sensing symmetry-breaking biphasic responses reaction-diffusion membrane and cortical tension cell fusion cortexillin cytokinesis Dictyostelium myosin symmetry breaking cytoplasmic flow phase-space analysis nonlinear waves actin polymerization bifurcation theory mass conservation spatial localization activator–inhibitor models developmental transitions cell polarization mathematical model fission yeast reaction–diffusion model small GTPases Cdc42 oscillations pseudopod Ras activation cytoskeleton chemotaxis neutrophils natural variation modelling activator-substrate mechanism mass-conserved models intracellular polarization partial differential equations sensitivity analysis GTPase activating protein (GAP) fission yeast Schizosaccharomyces pombe CRY2-CIBN optogenetics clustering positive feedback network evolution Saccharomyces cerevisiae polarity modularity neutrality |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557440703321 |
Goryachev Andrew | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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The Role of Extracellular Matrix in Cancer Development and Progression |
Autore | Tzanakakis George |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (182 p.) |
Soggetto topico | Research & information: general |
Soggetto non controllato |
elastin
ribosomal protein SA tongue carcinoma MMP-2 EGCG pancreatic ductal adenocarcinoma syndecans proteoglycans tumor progression angiogenesis syndecan-4 heparan sulfate cancer prognosis biomarker signal transduction proteoglycan metastasis extracellular matrix fibrosis immune cell modulation neutrophils neutrophil extracellular trap macrophages BCC MMP TIMP invasion lumican cancer cell growth motility hyaluronan RHAMM CD44 wound repair breast cancer malignant pleural mesothelioma pleural effusion extracellular vesicles biomarkers sulfated hyaluronan estrogen receptors epithelial-to-mesenchymal transition matrix metalloproteinases |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910566470803321 |
Tzanakakis George | ||
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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