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Biological Activities of Alkaloids: From Toxicology to Pharmacology
| Biological Activities of Alkaloids: From Toxicology to Pharmacology |
| Autore | Adamski Zbigniew |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (270 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
?-carboline
acetylcholinesterase acid-sensing ion channel subtype 1a acute toxicity alkaloid alkaloids antibacterial anticancer antifungal antimicrobial activity antioxidant antiviral apoptosis Apoptosis Arecoline beetles berberine Berberis thunbergii biodistribution bisbenzylisoquinoline alkaloid chanoclavine Chelidonium majus Corydalis lutea Curine cytotoxic activity cytotoxicity dehydrocrenatidine di-ester diterpenoid alkaloids Dicentra spectabilis EGFR endophyte Epichloë ergot alkaloids FAK Fumaria officinalis glycoalkaloids HPLC-DAD inflammation insect insect heart isoquinoline alkaloids leukemia lindoldhamine lipopolysaccharide livestock lung cancer cells mAchR3 Macleaya cordata macrophage Mahonia aquifolia malonyl-solamargine malonylated form Meconopsis cambrica mono-ester diterpenoid alkaloids n/a natural products natural sources neuropathic pain neutrophil nociception Ovarian cancer Palmatine plant secondary metabolites Radix Aconiti Lateralis preparations reproduction Rutidea parviflora sanguinarine secondary metabolites short-term and long-term usage solamargine Solanum melongena L. solasonine SRC Staphylococcus aureus subchronic feeding study Tenebrio molitor toxicology voltage-gated sodium channels |
| ISBN | 3-03928-928-4 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Biological Activities of Alkaloids |
| Record Nr. | UNINA-9910404082303321 |
Adamski Zbigniew
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cutting-Edge Topics in Dry Eye Disease
| Cutting-Edge Topics in Dry Eye Disease |
| Autore | Yoon Kyung Chul |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (158 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
aqueous-deficient dry eye
Bangladesh brief-type self-administered diet history questionnaire cross-sectional study cryosim-3 diabetes dry eye dry eye disease dry eye symptoms epidemiology fatty acids gabapentin global health graves' ophthalmopathy Houttuynia hyaluronan hylan A inflammation intense pulsed light Japanese meibography meibomian gland meibomian gland dysfunction meibomian glands meiboscore morphological changes multicenter nerve growth neuropathic keratopathy neuropathic pain neuropathy neurotrophic ocular surface disease questionnaire randomized trial severe keratitis systemic comorbidity TRPM8 agonist ultrasonic atomization vitamin D |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557367603321 |
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Yoon Kyung Chul
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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From a Molecule to a Drug: Chemical Features Enhancing Pharmacological Potential
| From a Molecule to a Drug: Chemical Features Enhancing Pharmacological Potential |
| Autore | Ribaudo Giovanni |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (234 p.) |
| Soggetto topico |
Medicine and Nursing
Pharmacology |
| Soggetto non controllato |
3-chymotrypsin-like protease
affinity chromatography alginate anti-ACE anti-DPP-IV anti-inflammatory drugs antioxidant activity benzoic acid derivatives big data binding free energy Box-Behken breast milk cannabinoid chemoinformatics chromatographic descriptors cisplatin clopidogrel coronavirus SARS-CoV-2 COVID-19 cyclooxygenase cytoprotection DFT calculations drug compounding drug discovery E-selectin Eucheuma gelatinae extraction fucoidan gallic acid gastrointestinal digestion high performance liquid chromatography ICAM-1 imine-enamine in silico L-selectin lithium therapy M/P ratio MCP-1 methadone hydrochloride microbiology molecular descriptors molecular docking molecular dynamics molecular dynamics simulations monocyte migration multitarget drug n/a nephrotoxicity neurocytology neuropathic pain neuroprotection NMR study one-pot oxone pain management paramyosin peroxymonosulfate pharmaceutical solutions pharmacodynamics pharmacokinetics physic-chemistry precision medicine protein binding pyrimidonic pharmaceuticals QSAR quercetin quercetin 3-O-glucuronide reaction mechanism reactivity parameters rheology SARS-CoV-2 seafood selenium selenoxide elimination sodium halide stability study statistical modeling target fishing thienopyridine THP-1 macrophage toxicology β-carrageenan |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | From a Molecule to a Drug |
| Record Nr. | UNINA-9910585940503321 |
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Ribaudo Giovanni
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Ion Channels as Marine Drug Targets
| Ion Channels as Marine Drug Targets |
| Autore | Sabatier Jean-Marc |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (134 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
antiarrhythmics
bioactives botulinum toxin A1 chemotherapy chitosan nanoparticles conantokins conotoxin conotoxins 2 Conus tulipa electrically induced arrhythmia guanidine alkaloid intraspecific variation ion channel modulators Kv1 latent TB mammalian NaV channel marine anti-TB compounds marine toxins modulators MTB net hunting strategy neuropathic pain nicotinic nirvana cabal paclitaxel pharmacological models of arrhythmia potassium channels proteomics PZA saxitoxin sea anemone toxins selective inhibitor sponges T-type CaV3.2 taxane transcriptomics TxVIA venomics voltage-gated sodium channel zetekitoxin AB α9α10 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557396203321 |
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Sabatier Jean-Marc
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mechanisms and New Targets for the Treatment of Chronic Pain
| Mechanisms and New Targets for the Treatment of Chronic Pain |
| Autore | Prostran Milica S |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 online resource (297 p.) |
| Soggetto topico |
Medicine and Nursing
Neurology and clinical neurophysiology |
| Soggetto non controllato |
analgesics
Chronic pain inflammatory pain neuropathic pain pain treatment visceral pain |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557679603321 |
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Prostran Milica S
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Natural Products and Drug Discovery
| Natural Products and Drug Discovery |
| Autore | Avato Pinarosa |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (392 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
2?
4?-dihydroxy-6?-methoxy-3? 5?-dimethylchalcone (DMC) ACE inhibitory peptide acetylated astragalosides aging angiogenesis anti-inflammatory activity antihypertensive antimicrobial agents antimicrobial resistance antinociceptive antioxidant activity artemisinin Astragalus boeticus L. Bacopa monnieri bioactive peptides bioactivities of natural products biotechnology C-glycoside Ca2+ cancer cardamonin cardiovascular disease celastrol cerebellum chemical derivatization chemosystematics chromatography circular dichroism Cleistocalyx operculatus Cuba cytokines cytotoxic activity cytotoxicity-guided Dasycladus vermicularis dementia devil's claw diabetes diabetic neuropathy dihydrochalcones Dryopteris fragrans Eruca sativa ESI-MS/MS Fabaceae Fideloside flavonoid flavonoids FSE glucoerucin glucosinolates GLUT4 glutamate growth inhibitory activity H2S Harpagophytum procumbens harpagoside HPLC HPLC-ESI-microTOF-Q-MS/MS human colon cancer cell lines Humulus lupulus hypertension immuno-regulation activity Imperata cylindrica inflammation isoflavones isolation and quantification ketamine Kv7 potassium channels L6 cell Lamiales LC-MS Leea indica Leishmania mexicana mexicana malaria marine peptides marine resources mass spectrometry metabolomics methicillin-resistant Staphylococcus aureus migration molecular network multivariate data analysis n/a NADPH oxidases natural products neuropathic pain NMR opioid Orobanchaceae Orobanche s.l. oxidative stress PANC-1 phenolic derivatives phenolics phenylethanoid glycosides phenylpropanoid glycosides Phyllanthus chamacristoides Phyllanthus orbicularis Physcomitrella patens pPancreatic cancer prenylated phenolic compounds proanthocyanidins proliferation psychosis secondary metabolites sesquiterpenoids siphonous green algae spagyric tincture spectroscopic analysis stereochemistry sulfated coumarins synergy T2DM terpenes terpenoids traditional medicine Trifolium TRPV1 Trypanosoma brucei brucei zebrafish |
| ISBN | 3-03928-747-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404086803321 |
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Avato Pinarosa
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Opioids and Their Receptors : Present and Emerging Concepts in Opioid Drug Discovery II
| Opioids and Their Receptors : Present and Emerging Concepts in Opioid Drug Discovery II |
| Autore | Spetea Mariana |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (260 p.) |
| Soggetto topico |
Chemistry
Research & information: general |
| Soggetto non controllato |
acetic acid-induced writhing test
allosteric modulation analgesia analgesic angiotensin receptors behavior beta-arrestin binding buprenorphine chemotype chloroquine cholestasis chronic pain colitis DAMGO delta opioid receptor deoxycholic acid epigenetics fluorescence cross-correlation spectroscopy (FCCS) free fatty acid receptors functional assay G protein-coupled receptor (GPCR) G-protein-biased agonist GPCR high-throughput screen hot-plate HS-731 human brain inverse agonist irreversible antagonist kappa opioid receptor agonist ligands lipids locomotor activity mice molecular docking molecular dynamics molecular dynamics simulations molecular pharmacology morphine dosing n/a N/OFQ nalbuphine neuropathic pain nociceptin nociceptin/orphanin FQ receptor non-competitive antagonist NOP receptor opioid opioid peptide opioid receptor opioid receptors peptide synthesis peripheral opioid agonist piperazine prodynorphin pruritis receptor binding studies rubiscolins scratching selectivity serotonin SR-17018 tail-clip TAT-HIV thiazole tolerance transcription β-amino acids δ opioid receptor µ-opioid analgesics µ-opioid receptor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Opioids and Their Receptors |
| Record Nr. | UNINA-9910576875203321 |
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Spetea Mariana
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Tight Junction and Its Proteins : More Than Just a Barrier
| The Tight Junction and Its Proteins : More Than Just a Barrier |
| Autore | Fromm Michael |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (432 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
actomyosin
adherens junction adherens junctions aging AMP-activated protein kinase (AMPK) angubindin-1 angulin anhidrosis antibiotic-associated hemorrhagic colitis antibody antidiuretic hormone apical junctional complex apoptosis aquaporin arachnoid barrier atopic dermatitis atypical aPKCζ barrier formation barrier function biliary epithelial cells blood-biliary barrier blood-brain barrier blood-cerebrospinal fluid barrier brain barriers calcium permeability Campylobacter jejuni cancer caspase CaSR celiac disease cell growth cell polarity cell-cell contact cerebral cavernous malformation chemoresistance cholangiocellular carcinoma cholestasis chronic liver disease claudin Claudin claudin 1 claudin targeting claudin-1 claudin-12 Claudin-14 claudin-2 claudin-5 Claudin-7 claudins ClC-2 CLDN14 Clostridium perfringens enterotoxin Clostridium perfringens iota-toxin co-culture cochlear implantation collecting duct curcumin cytokines disease dorsal root ganglion drinking rate drug development drug discovery endometrial cancer endothelia endothelial barrier enterocyte enteropathogenic E. coli (EPEC) environmental sensors epidermal barrier epithelia epithelial barrier epithelial barrier dysfunction epithelial fluid transport epithelial sodium channel (ENaC), collecting duct cells epithelial to mesenchymal transition epithelium EspF fibrosis gene transcription gland dysfunction glia limitans hearing loss HELIX syndrome Hepatitis C Virus hepatocellular carcinoma human hydrogen peroxide hydrostatic pressure hypermagnesemia hypertrophy hypokalemia immune cells in silico inflammation inflammatory bowel disease interleukin 13 intestinal mucosa intestine ion channel ion reabsorption ion transport ischemia junctional adhesion molecule kidney kidney stones Klebsiella oxytoca lipolysis-stimulated lipoprotein receptor (LSR) liver lung MAGUK proteins MDCK C7 cells MEKK3 membrane proteins metastasis mice migration molecular dynamics monocytes mouse colon mucosal immunology mucus mutations Mz-ChA-1 cells nephropathy nerve injury NES neuropathic pain neurovascular unit NFκB NHE2 NISCH syndrome NLS occludin organ preservation osmolality osmoregulation paracellular paracellular barrier paracellular channels and barriers paracellular permeability paracellular sodium transport paracellular transport paracellular water transport pathogens PDZ domain permeability phosphatidylcholine phosphorylation polarity proliferation protein domain protein interactions protein structure proximal tubule quercetin reconstructed human epidermis repair retinal pigment epithelium retinopathy Rho RhoA ROCK sensor single molecule localization microscopy skin sorting nexin 9 (SNX9) STAT3 stem cell stimulated emission depletion structured illumination microscopy super-resolution microscopy thick ascending limb tight epithelium tight junction tight junction assembly tight junctions tight junctions (TJ) tissue barrier TNF transepithelial electrical resistance (TER) transplantation tricellular tight junction tricellular tight junctions tricellulin tumor tumor suppressor UBE2Z ubiquitin vestibular function viral entry WNK4 ZO-1 ZO-2 zonula occludens |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Tight Junction and Its Proteins |
| Record Nr. | UNINA-9910557404603321 |
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Fromm Michael
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Tight Junction and Its Proteins: More Than Just a Barrier : More Than Just a Barrier
| The Tight Junction and Its Proteins: More Than Just a Barrier : More Than Just a Barrier |
| Autore | Fromm Michael |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (412 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
actomyosin
adherens junction adherens junctions aging AMP-activated protein kinase (AMPK) angubindin-1 angulin anhidrosis antibiotic-associated hemorrhagic colitis antibody antidiuretic hormone apical junctional complex apoptosis aquaporin arachnoid barrier atopic dermatitis atypical aPKCζ barrier formation barrier function biliary epithelial cells blood-biliary barrier blood-brain barrier blood-cerebrospinal fluid barrier brain barriers calcium permeability Campylobacter jejuni cancer caspase CaSR celiac disease cell growth cell polarity cell-cell contact cerebral cavernous malformation chemoresistance cholangiocellular carcinoma cholestasis chronic liver disease claudin Claudin claudin 1 claudin targeting claudin-1 claudin-12 Claudin-14 claudin-2 claudin-5 Claudin-7 claudins ClC-2 CLDN14 Clostridium perfringens enterotoxin Clostridium perfringens iota-toxin co-culture cochlear implantation collecting duct curcumin cytokines disease dorsal root ganglion drinking rate drug development drug discovery endometrial cancer endothelia endothelial barrier enterocyte enteropathogenic E. coli (EPEC) environmental sensors epidermal barrier epithelia epithelial barrier epithelial barrier dysfunction epithelial fluid transport epithelial sodium channel (ENaC), collecting duct cells epithelial to mesenchymal transition epithelium EspF fibrosis gene transcription gland dysfunction glia limitans hearing loss HELIX syndrome Hepatitis C Virus hepatocellular carcinoma human hydrogen peroxide hydrostatic pressure hypermagnesemia hypertrophy hypokalemia immune cells in silico inflammation inflammatory bowel disease interleukin 13 intestinal mucosa intestine ion channel ion reabsorption ion transport ischemia junctional adhesion molecule kidney kidney stones Klebsiella oxytoca lipolysis-stimulated lipoprotein receptor (LSR) liver lung MAGUK proteins MDCK C7 cells MEKK3 membrane proteins metastasis mice migration molecular dynamics monocytes mouse colon mucosal immunology mucus mutations Mz-ChA-1 cells nephropathy nerve injury NES neuropathic pain neurovascular unit NFκB NHE2 NISCH syndrome NLS occludin organ preservation osmolality osmoregulation paracellular paracellular barrier paracellular channels and barriers paracellular permeability paracellular sodium transport paracellular transport paracellular water transport pathogens PDZ domain permeability phosphatidylcholine phosphorylation polarity proliferation protein domain protein interactions protein structure proximal tubule quercetin reconstructed human epidermis repair retinal pigment epithelium retinopathy Rho RhoA ROCK sensor single molecule localization microscopy skin sorting nexin 9 (SNX9) STAT3 stem cell stimulated emission depletion structured illumination microscopy super-resolution microscopy thick ascending limb tight epithelium tight junction tight junction assembly tight junctions tight junctions (TJ) tissue barrier TNF transepithelial electrical resistance (TER) transplantation tricellular tight junction tricellular tight junctions tricellulin tumor tumor suppressor UBE2Z ubiquitin vestibular function viral entry WNK4 ZO-1 ZO-2 zonula occludens |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Tight Junction and Its Proteins |
| Record Nr. | UNINA-9910674057303321 |
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Fromm Michael
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Toxins and Cancer Therapy
| Toxins and Cancer Therapy |
| Autore | Snook Adam E |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (104 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
adoptive cell therapy
apoptosis autophagy botulinum neurotoxin botulinum toxin Burkitt lymphoma cancer cancer cells Coley's Toxins colorectal cancer cytokine therapy cytotoxic necrotizing factor type 1 drug discovery ER stress furin Gb3/CD77 glioblastoma gustatory hyperhidrosis immune checkpoint inhibitors immunotherapy immunotoxin intracellular trafficking n/a neuropathic pain parotid fistula parotid gland post-surgical pain protein purification recombinant protein production ribotoxin RNase T1 shiga toxins sialocele submaxillary gland vaccine α-sarcin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557123603321 |
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Snook Adam E
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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