Genomics and Models of Nerve Sheath Tumors
| Genomics and Models of Nerve Sheath Tumors |
| Autore | Hirbe Angela C |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (172 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
cancer
capmatinib chemoprevention clinical genetics COX-2 inhibitor CRISPR/Cas9 doxorubicin genetically engineered mouse models genomics heterogeneity kinase kinome adaptation kinome reprogramming latent variables machine learning malignancy malignant peripheral nerve sheath tumor malignant peripheral nerve sheath tumors mebendazole (MBZ) MEK MET metaVIPER mouse models MPNST nerve sheath tumor nerve sheath tumors neurofibromatosis neurofibromatosis 1 (NF1) neurofibromatosis type 1 neurofibromatosis type 1 syndrome neurofibromin 1 next generation sequencing NF1 pathology plexiform neurofibromas polycomb repressive complex PRC2 random forest sarcoma Schwann cells supervised learning tram transfer learning tumor deconvolution tumor evolution tumor microenvironment |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557484703321 |
Hirbe Angela C
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Lo trovi qui: Univ. Federico II | ||
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Updates on Molecular Targeted Therapies for CNS Tumors
| Updates on Molecular Targeted Therapies for CNS Tumors |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2023 |
| Descrizione fisica | 1 online resource (368 p.) |
| Soggetto topico |
Medicine and Nursing
Oncology |
| Soggetto non controllato |
A172
A2AAR antagonist adenosine adenosine receptors antigen processing and presentation antioxidant apoptosis ATRX bevacizumab biomarker blood-brain barrier brain metastasis brain tumor cancer metabolism cell cycle arrest central nervous system chemotherapy CNS disease CNS lymphoma CpG island diffuse midline gliomas DNMT EGFR ependymoma EPHB2 epidermal growth factor receptor ERK/MAPK pathway FGFR3 G-CIMP GBM germline mutation glioblastoma glioblastoma molecular classification glioma Group A Group B H3K27M histone acetylation IDH-mutant glioma immune evasion immune score immunotherapy intraparenchymal metastases intrathecal isotope labeling KIF11 leptomeningeal low grade glioma low-grade glioma LPS lung cancer lung carcinoma lung malignancy mass spectrometry meningitis MET metastatic disease Metformin methotrexate methylation methylomics methyltransferases MGMT molecular targets molecular therapy monoclonal antibodies MYCN myxopapillary n/a neoantigen neoplastic neurofibromatosis NF1 novel therapeutics novel therapies patient avatars PCNSL PDGFRA pediatric brain tumor PFA PFB PI3K/PTEN pathway plexiform neurofibroma potential therapy development preclinical models progression progression-free survival radiotherapy receptor tyrosine kinase RELA stereotactic radiosurgery subependymoma T cells T lymphocytes targeted therapy temozolomide tumor microenvironment tumor mutation burden tumor suppressor tyrosine kinase inhibitors U87MG vestibular schwannoma Warburg effect whole-brain radiation therapy YAP1 ZFTA |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9911053032003321 |
| MDPI - Multidisciplinary Digital Publishing Institute, 2023 | ||
| Lo trovi qui: Univ. Federico II | ||
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