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Biochemical Biomarkers and Neurodegenerative Diseases
| Biochemical Biomarkers and Neurodegenerative Diseases |
| Autore | Ciaccio Marcello |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (156 p.) |
| Soggetto topico |
Medicine
Neurosciences |
| Soggetto non controllato |
GLUT3
cerebral ischemia MCAO resveratrol astrocytes AMPK amyotrophic lateral sclerosis GSK3β neurodegenerative disease PD Arylsulfatase A lysosomes GWAS Gaucher's disease prognostic biomarker focused ultrasound MR-guided focused ultrasound high-intensity focused ultrasound ablation magnetic resonance imaging image quality stereotaxic techniques essential tremor Alzheimer's disease amyloid precursor protein Tyr682 residue YENPTY motif Fyn tyrosine kinase amyloid beta ALS biomarker beta amyloid AD biomarkers SARS-CoV-2 neuroinflammation neurodegenerative nisease nervous system Alzheimer's Disease Vitamin D 25(OH)D levels Vitamin D deficiency inherited neuromuscular disorders rare diseases multiple sclerosis genetic polymorphisms FOXP3 GATA3 vitamin D neuromelanin nigrosome-1 iron radiomics neurodegenerative diseases Parkinson's disease parkinsonian disorders |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557361103321 |
Ciaccio Marcello
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biomarkers in Neurodegenerative Diseases
| Biomarkers in Neurodegenerative Diseases |
| Autore | Ghosh Arnab |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (190 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Alzheimer's disease
amyloid beta hippocampus Kir channels K+ channels glioblastoma multiforme low-grade glioma astrocytoma recurrence multifocal growth mRNA expression MPS1 TTK therapy EDTA chelation therapy neurodegenerative diseases metal detoxification reactive oxygen species (ROS) neuroinflammation neurodegeneration cognitive dysfunction neurofibrillary tangles diagnosis methods biomarkers perinatal stress NURR1 inflammation late-onset diseases early life artificial neural network deep learning Parkinson's disease atypical parkinsonian syndrome dopamine transporter SPECT β-Amyloid calpain Collapsin Response Mediator Protein-2 human-neuroblastoma SH-SY5Y cells Somatostatin-14 somatostatin receptor brain injury quinpirole dopamine D2 receptors glial cell autophagy mitophagy multiple sclerosis biomarker neurons astrocytes Alzheimer's and Parkinson's diseases fluid and imaging biomarkers amyloid-β and tau miRNA extracellular vesicles exosomes and ectosomes PET radiotracers radiolabeled molecules |
| ISBN | 3-0365-5730-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910640000503321 |
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Ghosh Arnab
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biomarkers to Disentangle the Physiological from Pathological Brain Aging
| Biomarkers to Disentangle the Physiological from Pathological Brain Aging |
| Autore | Guerini F. G |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (246 p.) |
| Soggetto topico |
Science: general issues
Neurosciences |
| Soggetto non controllato |
neurodegenerative diseases
aging biomarkers bioimage analysis comorbidities |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557583403321 |
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Guerini F. G
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Centenarians-A Model to Study the Molecular Basis of Lifespan and Healthspan
| Centenarians-A Model to Study the Molecular Basis of Lifespan and Healthspan |
| Autore | Puca Annibale |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (204 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
aging
alternative therapy composition of royal jelly dietary interventions healthspan lifespan longevity royal jelly IGF-1 oxidative stress ageing nematode immunosenescence probiotic bacteria pathogen protection food allergy elderly hypersensitivity gut allergy inflammation redoxomics glutathione meniere's disease neurodegenerative diseases healthy aging DNA methylation epigenetic clocks telomere length centenarians exosomes serum functional enrichment analysis ingenuity pathway analysis miRNA-mRNA networks aging-related disease Di (2-Ethylhexyl) pthalate Hericium erinaceus vitagenes apoptosis mitochondrial respiratory complexes C. elegans polyphenols olive oil Parkinson's disease β-Dystroglycan cellular senescence lamin B1 DNA-damage response defective mitosis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557783503321 |
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Puca Annibale
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Coumarin and Its Derivatives
| Coumarin and Its Derivatives |
| Autore | Matos Maria João |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (406 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
coumarin
hydroxyl-modified coumarin photophysical thermal and structural characterization Glycyrrhiza uralensis glycyrol liquiritigenin cholinesterases human monoamine oxidases kinetics docking simulation chalcone neurodegenerative diseases adenosine receptors binding affinity docking 4-hydroxy-7-methoxycoumarin macrophage inflammation NF-κB MAPK calanolides pseudocalanolides calanolide A Calophyllum Calophyllaceae anti-HIV reverse transcriptase non-nucleoside reverse transcriptase inhibitors (NNRTIs) osthole umbelliferone esculin 4-hydroxycoumarin sorafenib apoptosis autophagy Yin Chen Hao constitutive androstane receptor scoparone coumarins quorum sensing QS inhibitors plant-derived molecules Chromobacterium violaceum immunoproteasome psoralen core non-peptidic electrophilic compounds warhead scan inflammatory bowel disease isocoumarin Crohn's disease ulcerative colitis glutathione oxidative stress complementary therapies intestinal inflammation benzopyrones five-membered aromatic heterocycles furan pyrrole thiophene selenophen dihydrocoumarin-fused dihydropyranones 3-aroylcoumarines benzyl 2,3-butadienoate 6'-(4-biphenyl)-β-iso-cinchonine biological applications drug discovery fluorescent probes warfarin acenocoumarol mechanical valve time in therapeutic range anticoagulation Ruta chalepensis Rutaceae chalepin chalepensin bioactivity biosynthesis coumarin3-carboxamides pyranocoumarins anticancer activity antibacterial activity free radical polymerization LED photocomposites direct laser write analytical methods model plant natural genetic variation natural products simple coumarins chalcocoumarin MAO-B molecular dynamics in silico studies dye-sensitized solar cells coumarin dyes thieno [3,2-b] thiophene charge transfer ethynylaryl esculetin antiplatelet activity impedance aggregometry COX polyphenols pyrazole imidazole thiazole oxazole triazole thiadiazole curcumin curcumin-coumarin hybrids neuroprotection monoamine oxidase inhibition cholinesterase inhibition scavenging activity Escherichia coli biotransformation ferulenol structural annotation in silico tools |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557577003321 |
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Matos Maria João
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Creatine Supplementation for Health and Clinical Diseases
| Creatine Supplementation for Health and Clinical Diseases |
| Autore | Kreider Richard B |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (562 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Food & society |
| Soggetto non controllato |
ergogenic aids
cellular metabolism phosphagens sarcopenia cognition diabetes creatine synthesis deficiencies concussion traumatic brain injury spinal cord injury muscle atrophy rehabilitation pregnancy immunity anti-inflammatory antioxidant anticancer creatine nutritional supplements fertility newborn development brain injury post-viral fatigue syndrome chronic fatigue syndrome GAA creatine kinase dietary supplements exercise skeletal muscle glycemic control type 2 diabetes mellitus phosphorylcreatine dietary supplement ergogenic aid youth athletes osteoporosis osteosarcopenia frailty cachexia innate immunity adaptive immunity inflammation macrophage polarization cytotoxic T cells toll-like receptors vascular pathology cardiovascular disease oxidative stress vascular health female menstrual cycle hormones exercise performance menopause mood children height BMI-for-age stature-for-age growth phosphocreatine creatine transporter supplementation treatment heart heart failure ischemia myocardial infarction anthracycline cardiac toxicity energy metabolism cell survival bioinformatics systems biology cellular allostasis dynamic biosensor pleiotropic effects of creatine (Cr) supplementation inflammatory bowel diseases (IBD) ulcerative colitis Crohn’s disease creatine kinase (CK) phosphocreatine (PCr) creatine transporter (CrT) intestinal epithelial cell protection intestinal tissue protection creatine perfusion organ transplantation Adenosine mono-phosphate (AMP) activated protein kinase (AMPK) liver kinase B1 (LKB1) mitochondrial permeability transition pore (mPTP) reactive oxygen species (ROS) glucose transporter (GLUT) T cell antitumor immunity metabolic regulator cancer immunotherapy supplements muscle damage recovery immobilization atrophy muscular dystrophy amyotrophic lateral sclerosis Parkinson’s Disease cardiopulmonary disease mitochondrial cytopathy hypertrophy athletic performance weightlifting resistance exercise training muscular power muscular adaptation muscle fatigue adipose tissue muscle strength physiological adaptation mitochondria thermogenesis MAP kinase signaling system sodium-chloride-dependent neurotransmitter symporters signal transduction intradialytic creatine supplementation hemodialysis muscle protein energy wasting clinical trial muscle weakness chronic fatigue cognitive impairment depression anemia resistance training sports nutrition strength toxicity methylation hyperhomocysteinemia neuromodulation MCDA mitochondriopathia cardiac infarction long COVID hypoxia stroke neurodegenerative diseases noncommunicable disease adenosine 5′-monopnophosphate-activated protein kinase anthracyclines creatine supplementation cardiac signaling cardiotoxicity doxorubicin soy vegetarian/vegan diet amino acids dietary ingredients performance |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566476003321 |
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Kreider Richard B
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Deep Learning in Aging Neuroscience
| Deep Learning in Aging Neuroscience |
| Autore | Ramírez Javier |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (127 pages) |
| Soggetto topico |
Science: general issues
Neurosciences |
| Soggetto non controllato |
deep learning
convolutional neural networks brain age estimation neurodegenerative diseases automated diagnosis brain image segmentation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557586903321 |
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Ramírez Javier
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Dual role of Microglia in Health and Disease: Pushing the Balance Towards Repair
| Dual role of Microglia in Health and Disease: Pushing the Balance Towards Repair |
| Autore | Ferreira Raquel |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (176 p.) |
| Soggetto topico |
Science: general issues
Neurosciences |
| Soggetto non controllato |
microglia
neuroinflammation intercellular communication neurodegenerative diseases cytokines phagocytosis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Dual role of Microglia in Health and Disease |
| Record Nr. | UNINA-9910557564803321 |
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Ferreira Raquel
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Functionally Relevant Macromolecular Interactions of Disordered Proteins
| Functionally Relevant Macromolecular Interactions of Disordered Proteins |
| Autore | Simon Istvan |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (520 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
intrinsically disordered proteins
epiproteome disordered protein platform molecular recognition feature post-translational modifications physiological homeostasis stress response RIN4 p53 molecular machines intrinsically disordered protein membrane-less organelle neurodegenerative disease p300 HAT acetylation post-translational modification protein aggregation Tau fibrillation intrinsically disorder proteins disorder-to-order regions protein–RNA interactions unstructured proteins conformational plasticity disordered protein folding ribosomal protein spectroscopy protein stability temperature response protein thermostability salt bridges meta strategy dual threshold significance voting decision tree based artificial neural network protein intrinsic disorder intrinsic disorder intrinsic disorder prediction intrinsically disordered region protein conformation transcriptome RNA sequencing Microarray differentially regulated genes gene ontology analysis functional analysis intrinsically disordered structural disorder correlated mutations co-evolution evolutionary couplings residue co-variation interaction surface residue contact network dehydron homodimer hydrogen bond inter-subunit interaction ion pair mutual synergistic folding solvent-accessible surface area stabilization center MLL proteins MLL4 lncRNA HOTAIR MEG3 leukemia histone lysine methyltransferase RNA binding protein hydration wide-line 1H NMR secretion immune extracellular protein-protein interaction structural domain evolution transcription factors DNA-protein interactions Sox2 sequential DNA loading smFRET DNA conformational landscape sequential DNA bending transcription factor dosage oligomer N-terminal prion protein copper binding prion disease mutations Nuclear pore complex FG-Nups phosphorylation coarse-grained CABS model MC simulations statistical force fields protein structure intrinsically disordered proteins (IDPs) neurodegenerative diseases aggregation drugs drug discovery plant virus eIF4E VPg potyvirus molten globule fluorescence anisotropy protein hydrodynamics |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557509403321 |
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Simon Istvan
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Interphase Between Aging and Neurodegenerative Diseases
| Interphase Between Aging and Neurodegenerative Diseases |
| Autore | Müller Walter E |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (129 p.) |
| Soggetto topico |
Science: general issues
Neurosciences |
| Soggetto non controllato |
neurodegenerative diseases
aging Parkinson's disease Alzheimer's disease neurodegeneration β-amyloid Aβ |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557258103321 |
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Müller Walter E
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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