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Anticancer Agents : Design, Synthesis and Evaluation
| Anticancer Agents : Design, Synthesis and Evaluation |
| Autore | Chen Qiao-Hong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (606 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
1,2,3-triazole
2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide 3,6-dibromocarbazole 4-(pyridin-4-yloxy)benzamide 5-bromoindole 5-fluorouracil ABCB1 (P-glycoprotein) actin ADME allene amides/esters androgen receptor anti-cancer activity anti-neuroinflammation anti-ovarian cancer anti-tumor anticancer anticancer activity anticancer agent anticancer agents anticancer compounds antimitotic agents antioxidant activity antiproliferative activity antiproliferative agent antitumor antitumor activity apalutamide apoptosis aromatase benzimidazole benzofuran-pyrazole benzofurans beta-lapachone bivalency breast cancer c-Met carbazole cell cycle chemical synthesis chemoresistance chrysin analogues colchiceine colchicine amide colchicine analogs colchicine sulfonamide colon cancer computational docking coumarin crystal structure cyanopyridone cytotoxic activity cytotoxic properties cytotoxicity darolutamide DFT study dihydroartemisinin dihydropyranoindole docking docking studies drug discovery drug resistance E-stereoselective enzalutamide enzyme inhibition estrone derivatives flavonoid flavonoids gemcitabine HDAC inhibitors HeLa HepG2 hydrates hydrazine IGF-1R IL-12 immune modulation indoleamine 2,3-dioxygenase inflammation inhibitor K562 kinase inhibitor MCF-7 MDM2-p53 interaction migration mimetics molecular simulation MOLT-4 multidrug resistance (MDR) reversal N-substituted pyrazoline nanoparticles natural product neuroblastoma NIH3T3 o-nitro-benzyl organosilicon compounds ortho-quinones ovarian cancer overcoming drug resistance P-glycoprotein P-MAPA PARP inhibitor PARP-1 inhibition phenylpyrazolopyrimidine photoactivatable protecting groups PI3Ks PI3Kα inhibitor PI3Kδ inhibitors polyvalency prodrug prostate cancer PROTACs protein degradation protein kinase protein-protein interactions Pyrazole pyrazolopyridine pyridotriazine quinazolin-4(3H)-one quinazolin-4(3H)-thione regioselective salinomycin Schiff base SILA-409 (Alis-409) SILA-421 (Alis-421) Src substituted pyridine synergy synthesis Talazoparib tanshione IIA taxoids thiazolidinone Thienopyrimidine thienopyrimidinone thiocolchicine thiopene thioxotriazopyridine TLR signaling topoisomerase II inhibitor triazolothiadiazine triple-negative breast cancer tryptophan metabolism tubulin inhibitors tumor specificity urea virtual screening xanthones yeast-based assays zampanolide βIII-tubulin |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Anticancer Agents |
| Record Nr. | UNINA-9910557129103321 |
Chen Qiao-Hong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Dual Specificity Phosphatases: From Molecular Mechanisms to Biological Function
| Dual Specificity Phosphatases: From Molecular Mechanisms to Biological Function |
| Autore | Pulido Rafael |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (240 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
asthma
astrocytes atypical dual-specificity phosphatases atypical DUSP BDNF brain metastasis cancer cannabinoids circulating tumor cells (CTCs) COPD Cpp1 cytokines DEPArray differentiation dual-specificity phosphatase dual-specificity phosphatases DUSP-4 DUSP10 E. coli infection fungal MKPs granule neurons HDAC6 (histone deacetylase isoform 6) hematopoietic cells HER2 hypertriglyceridemia inflammation influenza integrated omics analysis liver steatosis macrophage macrophages MAP Kinase Phosphatase-2 MAP kinase phosphatases MAP kinases MAPK MAPK phosphatase MAPKs microtubules mitogen-activated protein kinase MK-STYX (MAPK (mitogen-activated protein kinase) phosphoserine/threonine/tyrosine-binding protein) Mkp-1 Msg5 n/a neuroblastoma neuronal differentiation nucleotide receptors P2X7 P2Y13 Pmp1 post-translational modification proliferation protein stability pseudophosphatase respiratory viruses rhinovirus RSV Sdp1 sepsis signaling single cell analysis T cell TLR signaling triple-negative breast cancer (TNBC) ubiquitination |
| ISBN | 3-03921-689-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Dual Specificity Phosphatases |
| Record Nr. | UNINA-9910367740903321 |
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Pulido Rafael
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Polyamine Metabolism in Disease and Polyamine-Targeted Therapies / Tracy Murray-Stewart
| Polyamine Metabolism in Disease and Polyamine-Targeted Therapies / Tracy Murray-Stewart |
| Autore | Murray-Stewart Tracy |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (240 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
protein synthesis in cancer
neuroblastoma epigenetics Drosophila imaginal discs pneumococcal pneumonia transgenic mice spermidine/spermine N1-acetyl transferase ?-difluoromethylornithine MYC skeletal muscle protein expression curcumin colorectal cancer autophagy human embryonic kidney 293 (HEK293) melanoma tumor immunity Snyder-Robinson Syndrome Streptococcus pneumoniae B-lymphocytes autoimmunity spermine oxidase cell differentiation diferuloylmethane immunity antizyme transgenic mouse polyamine hirsutism chemoprevention CRISPR transglutaminase polyamine analogs NF-?B spermine synthase atrophy aging oxidative stress mast cells African sleeping sickness pancreatic ductal adenocarcinoma eflornithine carcinogenesis ornithine decarboxylase polyamine transport inhibitor putrescine neutrophils spermidine untranslated region spermine polyphenol M2 macrophages polyamine transport system metabolism difluoromethylorthinine DFMO antizyme inhibitors capsule polyamine transport eosinophils MCF-7 cells difluoromethylornithine polyamine metabolism mutant BRAF polyamines cadaverine proteomics airway smooth muscle cells breast cancer X-linked intellectual disability complementation T-lymphocytes bis(ethyl)polyamine analogs antizyme 1 cancer osteosarcoma |
| ISBN |
9783039211531
3039211536 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367757003321 |
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Murray-Stewart Tracy
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Role of MicroRNA in Cancer Development and Treatment
| Role of MicroRNA in Cancer Development and Treatment |
| Autore | Pulliero Alessandra |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (280 p.) |
| Soggetto topico |
Medicine and Nursing
Pharmacology |
| Soggetto non controllato |
air pollution
angiogenesis asbestos asbestos exposure biomarker biomarkers breast cancer cancer cancer prevention cancer stem cells carcinogenesis chemoresistance cutaneous tissues diagnosis DNA adducts early diagnosis early disease prevention environmental pollutants environmental risk factors epigenetic modulations epigenetics exposure extracellular vesicles fluoro-edenite genetic and microbiome markers genetic polymorphisms glioblastoma health technology assessment human in vitro study liquid biopsy lung cancer malignant mesothelioma mesothelioma metastases microbiota microRNA microRNAs miR-625 miRNA miRNAs mutations MYCN amplification n/a neuroblastoma no-smokers lung cancer nonsmokers lung cancer oncogenes oral squamous cell carcinoma ozone exposure plasticizers PRISMA prognosis public health genomics qPCR saliva |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576878603321 |
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Pulliero Alessandra
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression
| Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression |
| Autore | Stefanachi Angela |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (416 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
EGR-1
flavonoid (E)-5-((4-oxo-4H-chromen-3-yl)methyleneamino)-1-phenyl-1H-pyrazole-4-carbonitrile MDA-MB-231 MMP9 TNFα pancreatic ductal adenocarcinoma cyclodextrin inclusion complex phase solubility studies preformulation studies biphenylnicotinamide derivatives dual inhibitor EGFR VEGFR2 ligand-based pharmacophore molecular docking molecular dynamics leukemias doxorubicin inflammation drug delivery tumor targeting elastin-like polypeptide cell penetrating peptide matrix metalloproteinase doxorubicin resistance photosensitizer delivery system PAMAM dendrimer photodynamic therapy cytotoxicity phototoxicity colorectal adenocarcinoma dicarboximides chemical synthesis apoptosis kinases anticancer gene profiling SAR biomarkers colorectal cancer early detection examination liquid biopsy personalized medicine tumor treatment exosomes ctDNA CTC cytotoxic activity pyrazole derivatives MTT assay ADMET analysis single-crystal diffraction FTIR spectroscopy NMR spectroscopy thermogravimetric analysis acute myelogenous leukemia platelets microparticles γδ T cells immunotherapy tumor resistance combination therapy tumor microenvironment immune checkpoint inhibitor neuroblastoma molecular iodine cyclophosphamide xenografts metronomic therapy tamoxifen CYP2D6 MCF-7 Ishikawa cells SERM TNBC uterotrophic α-mangostin poly(amidoamine) dendrimer targeted drug delivery biotin targeting glioblastoma multiforme squamous cell carcinoma antiparasitic therapy diclofenac indomethacin oleanolic acid derivative conjugates NF-κB Nrf2 MAPKs PSN-1 cells reactive oxygen species glioblastoma brain tumor extracellular vesicles pancreatic cancer paclitaxel clathrin endocytosis sulforaphane nicotine metalloproteinase-9 gastric cancer cell invasion Arylquin 1 colon cancer tumor progression azelastine oxidative stress autophagy mitotic catastrophe chronic myeloid leukemia imatinib tyrosine kinase ketoconazole P-glycoprotein drug efflux transporter non-small-cell lung cancer cisplatin resistance aldehyde dehydrogenase isothiocyanates disulfiram epithelial to mesenchymal transition aminopeptidase N acetamidophenones Schiff bases semicarbazones thiosemicarbazones inhibition of proliferation |
| ISBN | 3-0365-5927-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639990003321 |
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Stefanachi Angela
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Systems Radiology and Personalized Medicine
| Systems Radiology and Personalized Medicine |
| Autore | de Jong Pim A |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (180 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
[11C]mHED
[123I]mIBG [124I]mIBG [18F]F-DOPA [18F]FDG [18F]mFBG [68Ga]Ga-DOTA peptides adiposity artificial intelligence atherosclerosis bloodstream infection body composition calcification pattern cardiorenal syndrome cerebral aneurysm chest X-ray chronic limb-threatening ischemia computational fluid dynamics computed tomography contrast media convolutional neural network COVID-19 cyst infection deep learning diffuse idiopathic skeletal hyperostosis endocarditis FDG-PET FDG-PET/CT Grad-CAM hemodynamic image analysis imaging imaging biomarker infection intra-abdominal fat large vessel vasculitis morphological MRI n/a neuroblastoma non-contrast nuclear medicine osteoarthritis peripheral arterial disease QFlow radiological imaging radionuclide imaging radiotracers reliability risk factors rupture spondylodiscitis tissue characterization total body PET/CT TRANCE vascular graft infection venography white blood cell scintigraphy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557748903321 |
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de Jong Pim A
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tea in Health and Disease / Q. Ping Dou
| Tea in Health and Disease / Q. Ping Dou |
| Autore | Dou Q. Ping |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (222 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
polyphenols
cell cycle arrest and apoptosis neuroblastoma salivary ?-amylase activity cancer apoptosis yaupon holly bioaccessibility fracture p53 tea Liubao tea BE(2)-C matrix metalloproteinase-1 (MMP-1) catechin renal stone oxalate protein expression 67LR Alzheimer's disease EGCG nutraceutical diseases anti-oxidant heme oxygenase-1 polyphenol anxiety matcha ERCC1/XPF neuro-sphere tea consumption theanine Rosmarinic acid yerba mate hypercalciuria gene expression microbiota cohort study histone deacetylase 2 (HDAC2) guayusa nuclear factor erythroid 2-related factor 2 (Nrf2) DNA repair mRNA expression caffeine chemoprevention cisplatin 6-OH-11-O-hydroxyphenanthrene adrenal hypertrophy hepatic damage anti-photoaging cell death green tea kudingcha suberoylanilide hydroxamic acid (SAHA) epigallocatechin gallate (EGCG) stress-reduction calcium oxalate monohydrate Camellia sinensis chemoresistance tea polyphenols green tea polyphenols green tea catechins N-MYC cancer epigallocatechin-gallate (EGCG) Parkinson's disease |
| ISBN |
9783038979876
3038979872 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346684203321 |
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Dou Q. Ping
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Venom and Toxin as Targeted Therapy / Hang Fai Henry Kwok
| Venom and Toxin as Targeted Therapy / Hang Fai Henry Kwok |
| Autore | Kwok Hang Fai Henry |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (180 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
cane toad
B cell non-Hodgkin lymphoma Malaysian cobras complement system decay accelerating factor neuroblastoma atopic dermatitis complement dependent cytotoxicity antioxidant enzymes bacterial adhesion cancer therapy N. kaouthia anuran skin secretion frog Apis mellifera syriaca solid phase extraction bee venom phospholipase A2 (bvPLA2) disintegrin toad toxins immunotoxins ribosome-inactivating proteins antimicrobial peptide (AMP) drug design Moxetumomab pasudotox snake venom antiviral activity in vitro effects bombesin-related peptide oxidative stress biomarkers half-life blood vessel formation target therapy 2 MYCN indolealkylamines Huachansu membrane attack complex bouganin bee venom SEM anticancer activity antimicrobial peptide house dust mite extract (DFE) mannose receptor O. hannah bicarinalin gastric cells melittin LC-ESI-MS dermaseptin smooth muscle apoptosis anticancer N. sumatrana Helicobacter pylori inflammation immunotherapy atopic dermatitis (AD) immunotoxin mantle cell lymphoma clearance mass spectrometry Bougainvillea rRNA N-glycosylase activity fungal toxin skin inflammation targeted therapy 4-dinitrochlorobenzene (DNCB) Bee venom VEGF Chansu bufadienolides obsessive-compulsive disorder (OCD) BLF1 antimicrobial activity orellanine VB6-845 acute lymphoblastic leukemia ribosome-inactivating protein CD206 molecular cloning cancer CD22 eIF4A |
| ISBN |
9783039211906
3039211900 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367754703321 |
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Kwok Hang Fai Henry
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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