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Animal Modeling in Cancer
| Animal Modeling in Cancer |
| Autore | Korinek Vladimir |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (273 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
soy
isoflavones mammary tumor prevention rodent models chemical carcinogens transgenic mice Zebrafish Drosophila rats mice NPM-1 FLT3 ITD ETO-1 IDH1/2 neural stem cells brain and nervous system cancers neurogenic niches radiotherapy sparing of neurogenic regions carcinoma consensus molecular subtypes intestine oncogenes signaling cascades tumor suppressors tumorigenesis MPN (myeloproliferative neoplasms) zebrafish iPSCs JAK2 MPL CALR thrombosis ubiquitin–proteasome system cancer mouse model gene inactivation colorectal cancer mouse models microbiota antitumor immunity melanoma mutation genetics animal model swine MeLiM progression spontaneous regression devitalization metaplasia Cdx animal models epigenetics xenotransplantation drug screen pre-clinical cancer model non-mouse models gene editing stem cells solid tumors hematologic malignancies |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557344403321 |
Korinek Vladimir
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antiviral Agents
| Antiviral Agents |
| Autore | Adamson Catherine |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (386 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Zika virus
nucleoside analogues antiviral agents NS5 prodrugs ProTides neural stem cells RNA-dependent RNA polymerase cytomegalovirus latent infection TALEN Surveyor nuclease mutation detection assay ie-1 gene quantitative real-time PCR Epstein-Barr virus herpes viruses lytic gene expression Burkitt lymphoma cells clozapine antipsychotic drug antiviral drug enteroviruses coxsackievirus B4 persistent infection fluoxetine resistance mutations herpes B virus macacine herpesvirus-1 genistein flavonoids acyclovir ganciclovir Plantago asiatica Clerodendrum trichotomum RSV therapeutic effects acteoside human antimicrobial peptides antiviral strategies defensins cathelicidins hepcidins transferrins influenza A virus brevilin A antiviral sesquiterpene lactone replication PRRSV polyethylenimine PEI virion internalization endocytosis HIV pediatrics Ethiopia pre-treatment drug resistance combination antiretroviral therapy (cART) dried plasma spots dried blood spots sphingolipids glycosphingolipids viruses lipid biosynthesis flavivirus Japanese encephalitis virus furin inhibitor precursor membrane protein measles virus central nervous system tropism treatments porcine reproductive and respiratory syndrome virus ginsenoside Rg1 antiviral activity pro-inflammatory factor NF-κB signaling pathway acute/latent infection congenital infection antiviral agent therapeutic strategies nucleic acid-based therapeutic approach HCMV vaccine adoptive cell therapy Rev response element chemical footprinting SHAPE drug discovery branched peptides herpesvirus immediate-early IE1 IE2 ribozyme RNA interference CRISPR/Cas small molecule orthohantavirus phenyl-benzotriazoles C-FRA Porcine circovirus type 2 epigallocatechin gallate heparan sulfate antiviral effect virus attachment microvirin lectin human immunodeficiency virus hepatitis C virus antiviral inhibitor non-immunogenic viral entry protein drugs LUMS1 oleanane-type derivatives influenza A virus (IAV) virus entry inhibitors hemagglutinin (HA) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557448703321 |
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Adamson Catherine
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Brain Nutrient Sensing in the Control of Energy Balance: New Insights and Perspectives
| Brain Nutrient Sensing in the Control of Energy Balance: New Insights and Perspectives |
| Autore | Cruciani-Guglielmacci Céline |
| Pubbl/distr/stampa | Frontiers Media SA, 2019 |
| Descrizione fisica | 1 electronic resource (114 p.) |
| Soggetto topico |
Science: general issues
Physiology |
| Soggetto non controllato |
nutrient sensing
energy balance hypothalamus olfactory bulb melanocortin system polyunsaturated fatty acids ceramides neural stem cells |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Brain Nutrient Sensing in the Control of Energy Balance |
| Record Nr. | UNINA-9910557756003321 |
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Cruciani-Guglielmacci Céline
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| Frontiers Media SA, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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PPARs as Key Mediators of Metabolic and Inflammatory Regulation
| PPARs as Key Mediators of Metabolic and Inflammatory Regulation |
| Autore | Vázquez-Carrera Manuel |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (456 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Biochemistry |
| Soggetto non controllato |
nuclear receptor
gene transcription inflammation molecular docking PPARβ/δ lung pulmonary artery GW0742 GSK3787 docking lipopolysaccharide (LPS) PPARγ ligand coumarin fluorescent ligand screening crystal structure PPAR atopic dermatitis psoriasis metabolic reprograming glucose fatty acids mycobacteria M. tuberculosis M. leprae PPARs lipid droplets metabolic alterations hepatic damage nuclear factors pharmacological targets AMPK GDF15 insulin resistance type 2 diabetes mellitus peroxisome proliferator-activated receptor gamma (PPARγ) real-time PCR ELISA immunohistochemistry signaling pathway PPAR gamma brain neural stem cells infection neuroinflammation HIV Zika cytomegalovirus neurogenesis microglia liver damage toll-like receptor 4 P2Y2 receptor metabolic syndrome resveratrol quercetin PPARα peroxisome β-oxidation PPRE ligand coregulator micronutrients PPARα knockout adipose tissue browning lipid metabolism depression PPARg neuropathology corticotropin releasing hormone norepinephrine subgenual prefrontal cortex amygdala nucleus accumbens common carotid artery occlusion electroretinography fibroblast growth factor 21 pemafibrate peroxisome proliferator-activated receptor alpha retinal ischemia skeletal muscle substrate metabolism nonalcoholic fatty liver disease (NAFLD) sex dimorphism lipidomics hepatic sex-biased gene expression PPARγ pulmonary arterial hypertension TGFβ vascular injury proliferation kidney fibrosis pattern-recognition receptors phagocytosis nitric oxide synthase fenofibrate oleoylethanolamide palmitoylethanolamide cancer immunity obesity diabetes miRNA DNA methylation histone modification peroxisome-proliferator-activated receptor fatty acid oxidation doping control regulatory T cells exercise nuclear receptors nutrigenomics energy homeostasis dairy animals non-alcoholic fatty liver disease (NAFLD) non-alcoholic steatohepatitis (NASH) peroxisome proliferator-activated receptors (PPAR) bezafibrate fenofibric acid peroxisome proliferator-activated receptor dual/pan agonist X-ray crystallography |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576873703321 |
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Vázquez-Carrera Manuel
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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