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Application of Bioinformatics in Cancers
| Application of Bioinformatics in Cancers |
| Autore | Brenner J. Chad |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (418 p.) |
| Soggetto non controllato |
cancer treatment
extreme learning independent prognostic power AID/APOBEC HP gene inactivation biomarkers biomarker discovery chemotherapy artificial intelligence epigenetics comorbidity score denoising autoencoders protein single-biomarkers gene signature extraction high-throughput analysis concatenated deep feature feature selection differential gene expression analysis colorectal cancer ovarian cancer multiple-biomarkers gefitinib cancer biomarkers classification cancer biomarker mutation hierarchical clustering analysis HNSCC cell-free DNA network analysis drug resistance hTERT variable selection KRAS mutation single-cell sequencing network target skin cutaneous melanoma telomeres Neoantigen Prediction datasets clinical/environmental factors StAR PD-L1 miRNA circulating tumor DNA (ctDNA) false discovery rate predictive model Computational Immunology brain metastases observed survival interval next generation sequencing brain machine learning cancer prognosis copy number aberration mutable motif steroidogenic enzymes tumor mortality tumor microenvironment somatic mutation transcriptional signatures omics profiles mitochondrial metabolism Bufadienolide-like chemicals cancer-related pathways intratumor heterogeneity estrogen locoregionally advanced RNA feature extraction and interpretation treatment de-escalation activation induced deaminase knockoffs R package copy number variation gene loss biomarkers cancer CRISPR overall survival histopathological imaging self-organizing map Network Analysis oral cancer biostatistics firehose Bioinformatics tool alternative splicing biomarkers diseases genes histopathological imaging features imaging TCGA decision support systems The Cancer Genome Atlas molecular subtypes molecular mechanism omics curative surgery network pharmacology methylation bioinformatics neurological disorders precision medicine cancer modeling miRNAs breast cancer detection functional analysis biomarker signature anti-cancer hormone sensitive cancers deep learning DNA sequence profile pancreatic cancer telomerase Monte Carlo mixture of normal distributions survival analysis tumor infiltrating lymphocytes curation pathophysiology GEO DataSets head and neck cancer gene expression analysis erlotinib meta-analysis traditional Chinese medicine breast cancer TCGA mining breast cancer prognosis microarray DNA interaction health strengthening herb cancer genomic instability |
| ISBN | 3-03921-789-5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367743403321 |
Brenner J. Chad
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biological and Pharmacological Activity of Plant Natural Compounds II
| Biological and Pharmacological Activity of Plant Natural Compounds II |
| Autore | Pezzani Raffaele |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (338 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
Bergenia species
botanical description traditional uses phytochemistry pharmacology anti-urolithiatic activity bergenin Flaxseed oil linusorb B3 anti-cancer apoptosis actin polymerization Src glioblastoma chlorogenic acid coffee cyclooxygenase espresso instant coffee platelet aggregation Rubia tinctorum L. antioxidants polyphenols ethylene glycol urolithiasis histophatology Saccharomyces cerevisiae β-glucan antimicrobial and anticancer activities detoxification ability immunomodulatory effect Aquilaria sinensis pheophorbide A MMP-2 MMP-9 HT-1080 advanced glycation end product (AGE) oxidative stress epithelial to mesenchymal transition AGE-inhibitor swertiamarin diabetic nephropathy astragaloside IV Astragalus membranaceus huang qi Astragali Radix liver liver regeneration 70% partial hepatectomy proliferation rat memory object recognition Ginkgo biloba dorsal hippocampus formation brain-derived neurotrophic factor Diclofenac γ-lactone nano-emulsion methylcellulose Ostrich oil Struthio camelus Caenorhabditis elegans leaf extract neuroprotection antioxidant activity DAF-16 Clerodendrum infortunatum terpenoids phenylpropanoids antidiabetic breast cancer Combretum indicum L. antidiabetic activity histopathology UPLC-QTOF/ESI-MS network pharmacology Biebersteinia heterostemon galegine hypotensive toxicity Sage Salvia officinalis cytotoxicity hepatoprotection MDA TAOxC MCF-7 HeLA cells HepG-2 cells Peganum harmala anti-inflammatory activity antioxidant LC-ESI-MS/MS traditional medicine rheumatoid arthritis rosmanol carnosol Callicarpa longissima TLR4/NF-κB/MAPK synergistic effect diabetes mellitus anti-diabetic drugs monoterpenes |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566486603321 |
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Pezzani Raffaele
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Network Pharmacology and Traditional Medicine
| Network Pharmacology and Traditional Medicine |
| Autore | Li Shao |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (438 p.) |
| Soggetto topico |
Science: general issues
Pharmacology |
| Soggetto non controllato |
network pharmacology
traditional medicine network target complex disease herbal formulae |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557213503321 |
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Li Shao
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Phytochemical Omics in Medicinal Plants
| Phytochemical Omics in Medicinal Plants |
| Autore | Chen Jen-Tsung |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (542 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
network pharmacology
traditional herbal medicine methodological trend polysaccharide fraction Trichoderma atroviride Salvia miltiorrhiza proteomics tanshinones Flos Chrysanthemi indici essential oil extraction method chemical composition biological activity Garcinia linii hypoglycemia benzopyran triterpene bioflavonoid phenolic in silico neurodegenerative diseases naringenin pharmacological targets signaling pathways molecular mechanisms drug delivery systems luteolin hyphenated techniques chromatography colorectal cancer diterpenes inflammatory bowel diseases Polyalthia longifolia herbal medicine DESs preparative-scale purification flavonoids 20-hydroxyecdysone Chenopodium quinoa Zinc oxide nanoparticles anticancer antileishmanial antimicrobial biocompatibility cancer apoptosis herbs cell lines in vivo quercetin polyphenols Alzheimer's disease mechanistic insights clinical directions isodon genus ent-kaurane diterpenoids natural compounds pathways medicinal plants bioactive compounds 4-hydroxynonenal deleterious effects Asiatic acid nasopharyngeal cancer cisplatin resistance MAPK pathway Anthocyanin Solanum nigrum L. flavonoid biosynthesis AtPAP1 licochalcone D non-small cell lung cancer reactive oxygen species Acorus gramineusand Euodia ruticarpa pro-/anti-inflammatory cytokines steam distillation essential oil Th1/Th2 cytokines lignans Trachelospermum asiaticum GNPS targeted isolation Rheum undulatum Glycyrriza uralensis hepatic encephalopathy MMP-9 neuroinflammation luteolin-7-O-glucoside oral cancer migration invasion MMP-2 Astragalus mongholicus ultraviolet-B radiation phenolics untargeted gas chromatography-mass spectrometry targeted liquid chromatography-mass spectrometry Bacopa monnieri cheminformatics neurological diseases spinocerebellar ataxia system pharmacology (-)-epigallocatechin-3-gallate (EGCG) bone morphogenetic protein-2 (BMP-2) catethin fracture healing local use cardiovascular diseases inflammation lipid metabolism non-coding RNA oxidative stress phenolic compounds Peucedanum ostruthium Apiaceae ELINA HetCA, STOCSY coumarines NF-ĸB VCAM-1 E-selectin Withaferin A matrix metalloproteinases antioxidant signaling Curcuma aromatica sesquiterpene anti-inflammatory luciferase assay cytotoxicity |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557507903321 |
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Chen Jen-Tsung
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Role of Natural Compounds in Inflammation and Inflammatory-Related Diseases
| Role of Natural Compounds in Inflammation and Inflammatory-Related Diseases |
| Autore | Maione Francesco |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (174 p.) |
| Soggetto non controllato |
toxicity
long-lasting effect iso-?-acids ammonium glycyrrhizinate metabolomics cytokines Alnus sibirica energy metabolism curcumin antineuroinflammation nitric oxide antioxidant nutraceutical food liver nardochinoid B endometriosis adipose tissue Nardostachys chinensis tau macrophage nociception heme oxygenase-1 enzymatic hydrolysis IL-6 nuciferine docking chronic nonbacterial prostatitis black tea polyphenol network pharmacology Tagetes patula L. SEM lipopolysaccharide solid lipid nanoparticle tauopathy memory lupane-type triterpene acute lung injury inducible nitric oxide synthase inflammation anti-inflammatory microglia resveratrol theaflavins hirsutanonol short-term high-fat diet inflammatory disease juçara oregonin PPARs NF-?B neuroprotection Portulaca oleracea TNF-? depression |
| ISBN | 3-03921-553-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367756703321 |
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Maione Francesco
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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