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Biological and Pharmacological Activity of Plant Natural Compounds
| Biological and Pharmacological Activity of Plant Natural Compounds |
| Autore | Pezzani Raffaele |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (296 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
natural products
phenylpropanoids phenolic acids plants depression behavioral disorders forced swim test tail suspension test anti-cancer activities multifloroside 10-oxyderivatives of oleoside secoiridoids structure-activity relationship flow cytometry epigallocatechin-3-gallate EGCG catechin green tea cancer preventive pharmacological activities Amelanchier alnifolia Nutt carriers powders bioactive compounds functional food Ageratina havanensis flavonoids UPLC-ESI-MS/MS P-glycoprotein antioxidant potential nootkatone anti-inflammatory acute inflammation granuloma Pharbitis nil colorectal cancer KRAS muscle function juglone NLRP3 inflammasome caspase-1 IL-1β IL-18 plant secondary metabolites natural compounds biological activity phytochemistry pharmacological activity plant side effects Talisia esculenta Brosimum gaudichaudii Genipa americana Bromelia antiacantha RA-3 nephrotoxicity triterpene antioxidant hyperuricemia Hibiscus acetosella phenolic compound antibacterial UPLC Tabebuia impetiginosa Taheebo traditional uses immunopharmacology immunological disorders hesperidin new-clean process extraction nanocrystals anti-ageing zingerone lipopolysaccharide inflammation anti-oxidant cytokine storm procalcitonin histopathology doxorubicin Mahonia aquifolium matrix metalloproteinases cytotoxicity human lung adenocarcinoma |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557471303321 |
Pezzani Raffaele
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biomarkers of Renal Diseases
| Biomarkers of Renal Diseases |
| Autore | García-Estañ Joaquín |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (276 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
poststreptococcal acute glomerulonephritis
infection-related glomerulonephritis nephritis-associated plasmin receptor plasmin acute kidney injury renal biomarkers furosemide stress test functional assessment urine diabetic kidney disease kidney function proteomics mass spectrometry statistical clinical model machine learning acute tubulointerstitial nephritis immunology biomarkers chronic kidney disease differential diagnosis label-free quantification renal transplant extracellular vesicles acute rejection chronic rejection chronic allograft dysfunction calcineurin-inhibitor nephrotoxicity Polyomavirus associated nephropathy immunosuppression upper urinary tract obstruction kidney injury neutrophil gelatinase-associated lipocalin monocyte chemotactic protein-1 kidney injury molecule 1 cystatin C vanin-1 microRNA uromodulin kidney graft function biomarker kidney transplantation long noncoding RNA rejection microvascular injury urinary aminopeptidases arterial hypertension renal function urinary biomarkers markers of AKI cystatin-C NGAL KIM-1 exercise end-stage kidney disease (ESKD) cardiovascular disease epidemiology CKD macrophage subpopulation renal fibrosis trichostatin A kidney graft T-cell-mediated rejection antibody-mediated rejection diagnostic test accuracy gentamicin sepsis miRNA nephrotoxicity vancomycin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557493003321 |
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García-Estañ Joaquín
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cadmium Sources and Toxicity
| Cadmium Sources and Toxicity |
| Autore | Satarug Soisungwan |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (130 p.) |
| Soggetto non controllato |
microRNAs
embryonic kidneys exposure assessment image analysis periodontal disease menopause nephrotoxicity urine protein mitochondrial morphology female alveolar bone population health glomerular filtration rate threshold limit biomarkers toxicity threshold limit osteotoxicity intrauterine exposure metabolic syndrome dietary cadmium periodontitis cadmium toxicity metabolic disruptor cadmium urine cadmium chronic kidney disease N-acetyl-?-d-glucosaminidase estimated glomerular filtration rate one health clinical kidney function measure ?2-microglobulin cause of death follow-up study menarche HIF-1 bioenergetics sub-lethal exposure metformin toxicological mechanism tubular dysfunction mitochondrial network environmental pollution mortality body burden indicator cancer hypertension |
| ISBN | 3-03897-985-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346850303321 |
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Satarug Soisungwan
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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From a Molecule to a Drug: Chemical Features Enhancing Pharmacological Potential
| From a Molecule to a Drug: Chemical Features Enhancing Pharmacological Potential |
| Autore | Ribaudo Giovanni |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (234 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
SARS-CoV-2
benzoic acid derivatives gallic acid molecular docking reactivity parameters selenoxide elimination one-pot imine-enamine reaction mechanism DFT calculations selenium anti-inflammatory drugs QSAR pain management cyclooxygenase multitarget drug cannabinoid neuropathic pain clopidogrel NMR study oxone peroxymonosulfate sodium halide thienopyridine drug discovery precision medicine pharmacodynamics pharmacokinetics coronavirus SARS-CoV-2 COVID-19 3-chymotrypsin-like protease pyrimidonic pharmaceuticals molecular dynamics simulations binding free energy β-carrageenan antioxidant activity Box-Behken extraction Eucheuma gelatinae physic-chemistry rheology quercetin quercetin 3-O-glucuronide cisplatin nephrotoxicity cytoprotection lithium therapy neurocytology toxicology neuroprotection chemoinformatics big data methadone hydrochloride pharmaceutical solutions drug compounding high performance liquid chromatography stability study microbiology fucoidan alginate L-selectin E-selectin MCP-1 ICAM-1 THP-1 macrophage monocyte migration protein binding breast milk M/P ratio statistical modeling molecular descriptors chromatographic descriptors affinity chromatography anti-ACE anti-DPP-IV gastrointestinal digestion in silico molecular dynamics paramyosin seafood target fishing |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | From a Molecule to a Drug |
| Record Nr. | UNINA-9910585940503321 |
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Ribaudo Giovanni
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pharmacogenomics and Personalized Medicine
| Pharmacogenomics and Personalized Medicine |
| Autore | Cecchin Erika |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (208 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
CYP2C9
VKORC1 warfarin warfarin initiation phase of therapy INR pharmacogenetics study pharmacogenomics pharmacogenetics genotype phenotype alleles precision medicine pharmacotranscriptomics high-throughput analysis childhood acute lymphoblastic leukemia clopidogrel acenocoumarol CDSS implementation azathioprine inflammatory bowel disease glutathione-S transferase pharmacokinetics nucleoside analogs microRNAs gene expression drug resistance AML cisplatin nephrotoxicity kidney injury genetic polymorphisms pre-emptive panel breast cancer subtype miRNA pathway crosstalk network precision drugs ovarian cancer platinum resistance focal copy number alterations whole exome sequencing personalized medicine human genetics pharmacology |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557287703321 |
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Cecchin Erika
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Physiology, Biochemistry, and Pharmacology of Transporters for Organic Cations
| Physiology, Biochemistry, and Pharmacology of Transporters for Organic Cations |
| Autore | Ciarimboli Giuliano |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (248 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
transporters
endogenous metabolism functional subgroups SLC22 remote sensing and signaling drug transporters gut microbiome chronic kidney disease solute carrier 22 (SLC22) Remote Sensing and Signaling Theory interorgan communication organic anion transporter organic cation transporter SLC22A15 SLC22A16 SLC22A18 kidney Malpighian tubule TCGA human pathology atlas gene ontology organic cations transport kidneys regulation Nuclear receptor renal excretion bile acids organic cation transporters drug disposition genetic polymorphisms drug-induced kidney injury nephrotoxicity RA Tofacitinib Baricitinib MATE1 solute carrier (SLC) family OCT1 SLC22A1 species differences drugs pesticides cisplatin nephrotoxicity PPAR-alpha organic transporters serotonin transporter plasma membrane monoamine transporter ketamine isoflurane serotonin clearance antidepressant-like activity chronoamperometry tail suspension test forced swim test hepatotoxicity solute carrier pulmonary drug delivery SLC22A1-5 lung epithelium drug uptake β2-agonists chronic lung diseases anticholinergics trospium OCT MATE drug excretion drug transport |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557346203321 |
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Ciarimboli Giuliano
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Advances and Clinical Outcomes of Kidney Transplantation : Volume 2
| Recent Advances and Clinical Outcomes of Kidney Transplantation : Volume 2 |
| Autore | Cheungpasitporn Wisit |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (270 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
malondialdehyde
oxidative stress new-onset diabetes renal transplantation BK virus BK virus nephropathy kidney allograft transplantation Alport syndrome children autosomal dominant polycystic kidney disease epidemiology hospitalization kidney transplantation subarachnoid hemorrhage malignancy post-transplant malignancy renal cell carcinoma meta-analysis systematic reviews tacrolimus C/D-ratio pharmacokinetics opportunistic infection allograft survival urological complications ureteric stent urinary tract infection timing of removal living donor ethnicity age obesity genetic relationship donor/recipient atypical hemolytic uremic syndrome eculizumab glucose intolerance insulin secretion insulin resistance oral glucose tolerance test healthy subject hyperchloremia kidney graft dysfunction living donor kidney transplantation Uropathogenic E. coli UPEC phylogeny genomics antibiotic resistance virulence traits night-time renal transplantation graft survival patient survival/outcome surgical complications acute rejection lymphocyte CD45RC Belatacept cardiovascular high risk outcome machine perfusion organ preservation temperature hypothermic normothermic transplant proton-pump inhibitors iron iron deficiency polyomavirus BKV kidney glomerulus BKVAN nephropathy fluid management delayed graft function goal-directed fluid therapy calcineurin inhibitor nephrotoxcity C/D ratio tacrolimus metabolism ADPKD native nephrectomy patient outcome perioperative complications epidermal growth factor creatinine graft failure new onset diabetes after renal transplantation single nucleotide polymorphisms urinary biomarkers α-GST π-GST nephrotoxicity urinary excretion of N1-methylnicotinamide mortality niacin status dietary intake tryptophan vitamin B3 Kidney transplant vitamin C cancer mortality mycophenolic acid immunosuppression plasmapheresis oxalate hyperoxaluria kidney transplant recipients post-transplantation diabetes mellitus all-cause mortality cardiovascular mortality infectious mortality magnesium hypomagnesaemia cancer kidney transplant survival living kidney donation living-donor kidney transplantation beliefs inequity ischemia reperfusion injury innate immune system adaptive immune system apoptosis necrosis hypoxic inducible factor endothelial dysfunction proton pump inhibitor transplant rejection GFR insulin-like growth factor 1 growth hormone muscle mass patient survival physical activity renal transplant recipients kidney transplant (KT) donor-specific antibodies (DSA) C3d-binding assay antibody-mediated rejection (AMR) arsenic diet fish consumption post-transplant diabetes mellitus N1-methyl-2-pyridone-5-carboxamide N1-methylnicotinamide urinary excretion kidney function biomarker branched chain amino acids posttransplant diarrhea methanogenesis Methanosphaera stadtmanae mucins sulfate-reducing bacteria acute humoral rejection first-line therapy outcomes proteasome inhibitor renal transplant transplant recipients calcineurin inhibitors FK506 pharmacokinetic fast tacrolimus metabolizers |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Recent Advances and Clinical Outcomes of Kidney Transplantation |
| Record Nr. | UNINA-9910557787303321 |
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Cheungpasitporn Wisit
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Advances and Clinical Outcomes of Kidney Transplantation
| Recent Advances and Clinical Outcomes of Kidney Transplantation |
| Autore | Cheungpasitporn Wisit |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (342 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
malondialdehyde
oxidative stress new-onset diabetes renal transplantation BK virus BK virus nephropathy kidney allograft transplantation Alport syndrome children autosomal dominant polycystic kidney disease epidemiology hospitalization kidney transplantation subarachnoid hemorrhage malignancy post-transplant malignancy renal cell carcinoma meta-analysis systematic reviews tacrolimus C/D-ratio pharmacokinetics opportunistic infection allograft survival urological complications ureteric stent urinary tract infection timing of removal living donor ethnicity age obesity genetic relationship donor/recipient atypical hemolytic uremic syndrome eculizumab glucose intolerance insulin secretion insulin resistance oral glucose tolerance test healthy subject hyperchloremia kidney graft dysfunction living donor kidney transplantation Uropathogenic E. coli UPEC phylogeny genomics antibiotic resistance virulence traits night-time renal transplantation graft survival patient survival/outcome surgical complications acute rejection lymphocyte CD45RC Belatacept cardiovascular high risk outcome machine perfusion organ preservation temperature hypothermic normothermic transplant proton-pump inhibitors iron iron deficiency polyomavirus BKV kidney glomerulus BKVAN nephropathy fluid management delayed graft function goal-directed fluid therapy calcineurin inhibitor nephrotoxcity C/D ratio tacrolimus metabolism ADPKD native nephrectomy patient outcome perioperative complications epidermal growth factor creatinine graft failure new onset diabetes after renal transplantation single nucleotide polymorphisms urinary biomarkers α-GST π-GST nephrotoxicity urinary excretion of N1-methylnicotinamide mortality niacin status dietary intake tryptophan vitamin B3 Kidney transplant vitamin C cancer mortality mycophenolic acid immunosuppression plasmapheresis oxalate hyperoxaluria kidney transplant recipients post-transplantation diabetes mellitus all-cause mortality cardiovascular mortality infectious mortality magnesium hypomagnesaemia cancer kidney transplant survival living kidney donation living-donor kidney transplantation beliefs inequity ischemia reperfusion injury innate immune system adaptive immune system apoptosis necrosis hypoxic inducible factor endothelial dysfunction proton pump inhibitor transplant rejection GFR insulin-like growth factor 1 growth hormone muscle mass patient survival physical activity renal transplant recipients kidney transplant (KT) donor-specific antibodies (DSA) C3d-binding assay antibody-mediated rejection (AMR) arsenic diet fish consumption post-transplant diabetes mellitus N1-methyl-2-pyridone-5-carboxamide N1-methylnicotinamide urinary excretion kidney function biomarker branched chain amino acids posttransplant diarrhea methanogenesis Methanosphaera stadtmanae mucins sulfate-reducing bacteria acute humoral rejection first-line therapy outcomes proteasome inhibitor renal transplant transplant recipients calcineurin inhibitors FK506 pharmacokinetic fast tacrolimus metabolizers |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557632603321 |
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Cheungpasitporn Wisit
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Toxic Metals, Chronic Diseases and Related Cancers
| Toxic Metals, Chronic Diseases and Related Cancers |
| Autore | Satarug Soisungwan |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (318 p.) |
| Soggetto topico | Public health & preventive medicine |
| Soggetto non controllato |
Trace elements
hair children hazardous waste incinerator Constantí (Catalonia, Spain) blood lead level boatyard childhood lead poisoning fishing community lead weights β2-microglobulin cadmium creatinine clearance glomerular filtration N-acetyl-β-d-glucosaminidase nephron mass nephrotoxicity trace elements autopsy tissues temporal trends creatinine excretion glomerular filtration rate lead kidney endocytosis metallothionein flow cytometry proximal tubule epithelial cells OGTT minimal model glucose response mechanism genotoxicity aluminum chloride rats food farmer PTWI (provisional tolerable monthly intake) TWI (tolerable weekly intake) Monte Carlo simulation mercury obesogen lipid profiles hyperlipidemia elevated liver enzymes hexavalent chromium [Cr(VI)] mitochondrial fragmentation dynamin-related protein 1 (Drp1) mitochondrial respiratory chain complex I (MRCC I) reactive oxygen species (ROS) blood lead cellular immunity phagocytosis humoral munity immunosuppression insulin diabetes hyperglycemia hyperinsulinemia lipogenic β-cell toxicity stroke cerebrovascular accident heavy metal rare earth element case-control study mortality lifetime cadmium intake renal diseases urinary cadmium a follow-up study diet kidney function chronic kidney disease threshold limit tolerable intake level heavy metals birth weight preterm birth diet pattern Mediterranean diet pregnancy toxic metals reproduction testicular and ovarian structure |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580214603321 |
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Satarug Soisungwan
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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