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Impaired Mitochondrial Bioenergetics under Pathological Conditions
| Impaired Mitochondrial Bioenergetics under Pathological Conditions |
| Autore | Lenaz Giorgio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (460 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Biochemistry |
| Soggetto non controllato |
aging heart
Bcl-2 family mitochondria programmed cell death fatty acid oxidation palmitate oleate m.3243A> G mutation MT-ATP6 m.8909T> C ATP synthase nephropathy oxidative phosphorylation mitochondrial disease cardiolipin Barth syndrome Sengers syndrome respiratory chain Dilated Cardiomyopathy with Ataxia cardiomyopathy mammalian complex I NADH dehydrogenase complex I assembly complex I structure complex I deficiency supernumerary subunits electron transport chain mitochondrial dysfunction Leigh syndrome mitochondrial diseases yeast Saccharomyces cerevisiae pet mutants pancreatic endocrine cells mathematical model cellular bioenergetics diabetes glucagon insulin exercise immune system metabolic disease COVID-19 mitochondrial dynamics viral infections MAVS RIG-I MDA5 innate immune response SARS CoV-2 RSV influenza respiratory supercomplexes ROS ATP synthase/hydrolase mitochondrial permeability transition pore cristae cellular signaling human disease mitochondrial dynamic cell signaling cancer respiratory complexes oxidative stress mitochondrial DNA MTCYB mutations cytochrome b complex III aging energy metabolism entorhinal cortex lipoxidation-derived damage neurodegeneration oxidative damage protein import respiratory complex assembly supercomplexes mitochondrial proteostasis heart failure bioenergetics assembly factor atypical myopathy high-resolution respirometry toxicity assays cell culture equine primary myoblasts fibroblasts frozen tissue leukocytes oxygen consumption platelets respirometry skeletal muscle |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585934503321 |
Lenaz Giorgio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Advances and Clinical Outcomes of Kidney Transplantation : Volume 2
| Recent Advances and Clinical Outcomes of Kidney Transplantation : Volume 2 |
| Autore | Cheungpasitporn Wisit |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (270 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
malondialdehyde
oxidative stress new-onset diabetes renal transplantation BK virus BK virus nephropathy kidney allograft transplantation Alport syndrome children autosomal dominant polycystic kidney disease epidemiology hospitalization kidney transplantation subarachnoid hemorrhage malignancy post-transplant malignancy renal cell carcinoma meta-analysis systematic reviews tacrolimus C/D-ratio pharmacokinetics opportunistic infection allograft survival urological complications ureteric stent urinary tract infection timing of removal living donor ethnicity age obesity genetic relationship donor/recipient atypical hemolytic uremic syndrome eculizumab glucose intolerance insulin secretion insulin resistance oral glucose tolerance test healthy subject hyperchloremia kidney graft dysfunction living donor kidney transplantation Uropathogenic E. coli UPEC phylogeny genomics antibiotic resistance virulence traits night-time renal transplantation graft survival patient survival/outcome surgical complications acute rejection lymphocyte CD45RC Belatacept cardiovascular high risk outcome machine perfusion organ preservation temperature hypothermic normothermic transplant proton-pump inhibitors iron iron deficiency polyomavirus BKV kidney glomerulus BKVAN nephropathy fluid management delayed graft function goal-directed fluid therapy calcineurin inhibitor nephrotoxcity C/D ratio tacrolimus metabolism ADPKD native nephrectomy patient outcome perioperative complications epidermal growth factor creatinine graft failure new onset diabetes after renal transplantation single nucleotide polymorphisms urinary biomarkers α-GST π-GST nephrotoxicity urinary excretion of N1-methylnicotinamide mortality niacin status dietary intake tryptophan vitamin B3 Kidney transplant vitamin C cancer mortality mycophenolic acid immunosuppression plasmapheresis oxalate hyperoxaluria kidney transplant recipients post-transplantation diabetes mellitus all-cause mortality cardiovascular mortality infectious mortality magnesium hypomagnesaemia cancer kidney transplant survival living kidney donation living-donor kidney transplantation beliefs inequity ischemia reperfusion injury innate immune system adaptive immune system apoptosis necrosis hypoxic inducible factor endothelial dysfunction proton pump inhibitor transplant rejection GFR insulin-like growth factor 1 growth hormone muscle mass patient survival physical activity renal transplant recipients kidney transplant (KT) donor-specific antibodies (DSA) C3d-binding assay antibody-mediated rejection (AMR) arsenic diet fish consumption post-transplant diabetes mellitus N1-methyl-2-pyridone-5-carboxamide N1-methylnicotinamide urinary excretion kidney function biomarker branched chain amino acids posttransplant diarrhea methanogenesis Methanosphaera stadtmanae mucins sulfate-reducing bacteria acute humoral rejection first-line therapy outcomes proteasome inhibitor renal transplant transplant recipients calcineurin inhibitors FK506 pharmacokinetic fast tacrolimus metabolizers |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Recent Advances and Clinical Outcomes of Kidney Transplantation |
| Record Nr. | UNINA-9910557787303321 |
|
Cheungpasitporn Wisit
|
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Recent Advances and Clinical Outcomes of Kidney Transplantation
| Recent Advances and Clinical Outcomes of Kidney Transplantation |
| Autore | Cheungpasitporn Wisit |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (342 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
malondialdehyde
oxidative stress new-onset diabetes renal transplantation BK virus BK virus nephropathy kidney allograft transplantation Alport syndrome children autosomal dominant polycystic kidney disease epidemiology hospitalization kidney transplantation subarachnoid hemorrhage malignancy post-transplant malignancy renal cell carcinoma meta-analysis systematic reviews tacrolimus C/D-ratio pharmacokinetics opportunistic infection allograft survival urological complications ureteric stent urinary tract infection timing of removal living donor ethnicity age obesity genetic relationship donor/recipient atypical hemolytic uremic syndrome eculizumab glucose intolerance insulin secretion insulin resistance oral glucose tolerance test healthy subject hyperchloremia kidney graft dysfunction living donor kidney transplantation Uropathogenic E. coli UPEC phylogeny genomics antibiotic resistance virulence traits night-time renal transplantation graft survival patient survival/outcome surgical complications acute rejection lymphocyte CD45RC Belatacept cardiovascular high risk outcome machine perfusion organ preservation temperature hypothermic normothermic transplant proton-pump inhibitors iron iron deficiency polyomavirus BKV kidney glomerulus BKVAN nephropathy fluid management delayed graft function goal-directed fluid therapy calcineurin inhibitor nephrotoxcity C/D ratio tacrolimus metabolism ADPKD native nephrectomy patient outcome perioperative complications epidermal growth factor creatinine graft failure new onset diabetes after renal transplantation single nucleotide polymorphisms urinary biomarkers α-GST π-GST nephrotoxicity urinary excretion of N1-methylnicotinamide mortality niacin status dietary intake tryptophan vitamin B3 Kidney transplant vitamin C cancer mortality mycophenolic acid immunosuppression plasmapheresis oxalate hyperoxaluria kidney transplant recipients post-transplantation diabetes mellitus all-cause mortality cardiovascular mortality infectious mortality magnesium hypomagnesaemia cancer kidney transplant survival living kidney donation living-donor kidney transplantation beliefs inequity ischemia reperfusion injury innate immune system adaptive immune system apoptosis necrosis hypoxic inducible factor endothelial dysfunction proton pump inhibitor transplant rejection GFR insulin-like growth factor 1 growth hormone muscle mass patient survival physical activity renal transplant recipients kidney transplant (KT) donor-specific antibodies (DSA) C3d-binding assay antibody-mediated rejection (AMR) arsenic diet fish consumption post-transplant diabetes mellitus N1-methyl-2-pyridone-5-carboxamide N1-methylnicotinamide urinary excretion kidney function biomarker branched chain amino acids posttransplant diarrhea methanogenesis Methanosphaera stadtmanae mucins sulfate-reducing bacteria acute humoral rejection first-line therapy outcomes proteasome inhibitor renal transplant transplant recipients calcineurin inhibitors FK506 pharmacokinetic fast tacrolimus metabolizers |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557632603321 |
|
Cheungpasitporn Wisit
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The Tight Junction and Its Proteins : More Than Just a Barrier
| The Tight Junction and Its Proteins : More Than Just a Barrier |
| Autore | Fromm Michael |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (432 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
tissue barrier
tight junction claudins tricellulin tight junctions organ preservation intestine transplantation ischemia intestinal mucosa lung epithelia interleukin 13 UBE2Z ubiquitin osmolality hydrostatic pressure cancer sensor tricellular tight junctions endometrial cancer epithelial barrier dysfunction Claudin-7 permeability WNK4 epithelial sodium channel (ENaC), collecting duct cells claudin-1 hydrogen peroxide phosphorylation claudin angulin drug development angubindin-1 Clostridium perfringens enterotoxin Clostridium perfringens iota-toxin antibody Mz-ChA-1 cells biliary epithelial cells phosphatidylcholine mucus paracellular transport atopic dermatitis cytokines STAT3 ZO-2 cholestasis gene transcription hypertrophy tumor suppressor NLS NES CaSR RhoA barrier function paracellular permeability antidiuretic hormone Claudin-14 CLDN14 hearing loss vestibular function cochlear implantation Hepatitis C Virus viral entry epidermal barrier reconstructed human epidermis claudin targeting Campylobacter jejuni curcumin apoptosis co-culture mouse colon TNF NFκB lipolysis-stimulated lipoprotein receptor (LSR) epithelial barrier cell–cell contact caspase kidney stones ion reabsorption quercetin brain barriers blood-brain barrier neurovascular unit blood-cerebrospinal fluid barrier arachnoid barrier glia limitans adherens junctions paracellular sodium transport thick ascending limb nephropathy HELIX syndrome hypokalemia hypermagnesemia anhidrosis gland dysfunction aging blood–brain barrier mutations kidney liver skin human mice disease in silico drug discovery membrane proteins protein interactions molecular dynamics antibiotic-associated hemorrhagic colitis Klebsiella oxytoca tight junction assembly monocytes celiac disease claudin-2 epithelium inflammation fibrosis proliferation migration tricellular tight junction paracellular water transport tight epithelium MDCK C7 cells cell growth endothelia adherens junction apical junctional complex AMP-activated protein kinase (AMPK) paracellular barrier protein structure protein domain occludin junctional adhesion molecule zonula occludens MAGUK proteins PDZ domain stem cell chemoresistance retinal pigment epithelium retinopathy barrier formation collecting duct claudin-5 neuropathic pain nerve injury dorsal root ganglion enteropathogenic E. coli (EPEC) tight junctions (TJ) polarity atypical aPKCζ transepithelial electrical resistance (TER) sorting nexin 9 (SNX9) EspF claudin 1 tumor metastasis epithelial to mesenchymal transition cerebral cavernous malformation endothelial barrier Rho ROCK MEKK3 ion transport ion channel super-resolution microscopy structured illumination microscopy stimulated emission depletion single molecule localization microscopy Claudin blood-biliary barrier chronic liver disease hepatocellular carcinoma cholangiocellular carcinoma NISCH syndrome repair NHE2 ClC-2 inflammatory bowel disease mucosal immunology ZO-1 actomyosin aquaporin drinking rate epithelial fluid transport enterocyte osmoregulation paracellular proximal tubule calcium permeability claudin-12 paracellular channels and barriers cell polarity pathogens immune cells environmental sensors |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Tight Junction and Its Proteins |
| Record Nr. | UNINA-9910557404603321 |
|
Fromm Michael
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The Tight Junction and Its Proteins: More Than Just a Barrier : More Than Just a Barrier
| The Tight Junction and Its Proteins: More Than Just a Barrier : More Than Just a Barrier |
| Autore | Fromm Michael |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (412 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
tissue barrier
tight junction claudins tricellulin tight junctions organ preservation intestine transplantation ischemia intestinal mucosa lung epithelia interleukin 13 UBE2Z ubiquitin osmolality hydrostatic pressure cancer sensor tricellular tight junctions endometrial cancer epithelial barrier dysfunction Claudin-7 permeability WNK4 epithelial sodium channel (ENaC), collecting duct cells claudin-1 hydrogen peroxide phosphorylation claudin angulin drug development angubindin-1 Clostridium perfringens enterotoxin Clostridium perfringens iota-toxin antibody Mz-ChA-1 cells biliary epithelial cells phosphatidylcholine mucus paracellular transport atopic dermatitis cytokines STAT3 ZO-2 cholestasis gene transcription hypertrophy tumor suppressor NLS NES CaSR RhoA barrier function paracellular permeability antidiuretic hormone Claudin-14 CLDN14 hearing loss vestibular function cochlear implantation Hepatitis C Virus viral entry epidermal barrier reconstructed human epidermis claudin targeting Campylobacter jejuni curcumin apoptosis co-culture mouse colon TNF NFκB lipolysis-stimulated lipoprotein receptor (LSR) epithelial barrier cell–cell contact caspase kidney stones ion reabsorption quercetin brain barriers blood-brain barrier neurovascular unit blood-cerebrospinal fluid barrier arachnoid barrier glia limitans adherens junctions paracellular sodium transport thick ascending limb nephropathy HELIX syndrome hypokalemia hypermagnesemia anhidrosis gland dysfunction aging blood–brain barrier mutations kidney liver skin human mice disease in silico drug discovery membrane proteins protein interactions molecular dynamics antibiotic-associated hemorrhagic colitis Klebsiella oxytoca tight junction assembly monocytes celiac disease claudin-2 epithelium inflammation fibrosis proliferation migration tricellular tight junction paracellular water transport tight epithelium MDCK C7 cells cell growth endothelia adherens junction apical junctional complex AMP-activated protein kinase (AMPK) paracellular barrier protein structure protein domain occludin junctional adhesion molecule zonula occludens MAGUK proteins PDZ domain stem cell chemoresistance retinal pigment epithelium retinopathy barrier formation collecting duct claudin-5 neuropathic pain nerve injury dorsal root ganglion enteropathogenic E. coli (EPEC) tight junctions (TJ) polarity atypical aPKCζ transepithelial electrical resistance (TER) sorting nexin 9 (SNX9) EspF claudin 1 tumor metastasis epithelial to mesenchymal transition cerebral cavernous malformation endothelial barrier Rho ROCK MEKK3 ion transport ion channel super-resolution microscopy structured illumination microscopy stimulated emission depletion single molecule localization microscopy Claudin blood-biliary barrier chronic liver disease hepatocellular carcinoma cholangiocellular carcinoma NISCH syndrome repair NHE2 ClC-2 inflammatory bowel disease mucosal immunology ZO-1 actomyosin aquaporin drinking rate epithelial fluid transport enterocyte osmoregulation paracellular proximal tubule calcium permeability claudin-12 paracellular channels and barriers cell polarity pathogens immune cells environmental sensors |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Tight Junction and Its Proteins |
| Record Nr. | UNINA-9910674057303321 |
|
Fromm Michael
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||