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Anticancer Properties of Natural and Derivative Products
| Anticancer Properties of Natural and Derivative Products |
| Autore | Lupiáñez José Antonio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (312 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
total phenolic content
total flavonoid content GC-MS DPPH antioxidant anticancer agent anti-inflammatory agent gingival fibroblasts oral cancer natural extract Adenosma bracteosum extract anti-cancer cell line isolated compounds caspase-3 bioactive compounds metabolites wine grapes breast cancer chemoprevention chemotherapy squamous cell carcinoma Moringa oleifera 3-hydroxy-β-ionone antioxidant activity antioxidant enzymes anti-proliferative activity maslinic acid melanoma Olea europaea L. ROS levels photodynamic therapy cancer photosensitiser natural compounds Elaeagnus angustifolia EMT apoptosis AKT/PI3K signaling pathway human hepatocarcinoma HepG2 cells migration activity proliferation oxidative stress ROS level uvaol lung metastases in vivo complementary medicine medicinal mushrooms triterpenoic acid tormentic acid betulinic acid oleanolic acid rhodamine B cytotoxicity hepatocellular carcinoma (HCC) Pogostemon cablin (PPa extract) cell cycle synergism natural photosensitive compounds anticancer activity hypericin emodin quinizarin danthron interaction DNA glioblastoma (GBM) lactucopicrin (LCTP) temozolomide (TMZ) autophagy NF-κB p62/SQSM1 natural product therapeutic triglyceride xenograft study Caveolin-1 actin cytoskeleton betulin glycoconjugates click chemistry 1,3-dipolar cycloaddition |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557370303321 |
Lupiáñez José Antonio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antimicrobial compounds from natural sources [[electronic resource] /] / topic editors: Mirian A. Hayashi, Fernando C. Bizerra and Pedro Ismael Da Silva Jr
| Antimicrobial compounds from natural sources [[electronic resource] /] / topic editors: Mirian A. Hayashi, Fernando C. Bizerra and Pedro Ismael Da Silva Jr |
| Autore | Pedro Ismael Da Silva Jr |
| Pubbl/distr/stampa | Frontiers Media SA, 2014 |
| Descrizione fisica | 1 online resource (149 pages) : illustrations; digital, PDF file(s) |
| Disciplina | 615.792 |
| Collana |
Frontiers in microbiology
Frontiers Research Topics |
| Soggetto topico |
Anti-infective agents
Medicinal plants - Research Medical microbiology Microbiology |
| Soggetto non controllato |
antimicrobial
natural compounds antiseptic preservation Peptides |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910137210603321 |
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Pedro Ismael Da Silva Jr
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| Frontiers Media SA, 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antitumoral Properties of Natural Products
| Antitumoral Properties of Natural Products |
| Autore | Fabiani Roberto |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (344 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
cytotoxic activity
NCI-60 cancer cell line pristimerin Salacia crassifolia Celastraceae Brazilian Cerrado biome Salacia elliptica Cheiloclinium cognatum Plenckia populnea Aspergillus fumigatus Cordyceps sinensis isochromanes chiral resolution ECD calculation cytotoxicity coronarin D JNK osteosarcoma Zeylenone gastric cancer invasion migration apoptosis anti-cancer agents anthraquinones glycosyltransferase Dendrobium officinale structure elucidation anti-tumor activity plantation mode AR Ganoderma tsugae lipogenesis prostate cancer SREBP-1 ursolic acid betulinic acid triterpenoids necrotic quercetin quercetagetin patuletin lichen secondary metabolites tumidulin stemness potential colorectal cancer cells oncogene transcriptional regulation neferine FAK/S6K1 autophagy human neuroblastoma cells natural yellow Monascus pigments water-soluble antioxidation MCF-7 cells phloretin cell proliferation inflammation glucose uptake Catalpa speciosa Taxus cuspidata Magnolia acuminata phenols antioxidants anticancer Colocasia esculenta food bioactive tarin stable nanocapsules entrapment efficiency no-toxicity preclinical tests antitumoral activity chemotherapeutic adjuvant grape leaves ASE TP Antioxidant activities Antiproliferative pro-apoptotic effects Gene expression Nutraceuticals Cucurbitacin B gefitinib-resistant NSCLC EGFR lysosomal degradation CIP2A zerumbone cancer NF-κB IL-6/JAK2/STAT3 Akt FOXO1 multiple myeloma quality control naringenin flavonoids traditional preparation cancer stem cells phytochemicals plant-derived foods fruit vegetable cell signaling Artemisia absinthium endoplasmic reticulum stress mitochondrial-dependent pathway melanoma bee venom melittin temozolomide AKT MAPK antrodin C mTOR metabolic stability capsazepine inflammatory diseases ROS TRPV1 PI3K/AKT/mTOR CLE-10 LC3 MDA-MB-231 lactoferrin hydrolysate copper manganese gastric cancer cells anti-cancer activity molecular mechanism natural product alkaloids cephalotaxine protein synthesis inhibition antiproliferation agents folk medicine DLD-1 cells doxorubicin chemotherapy drug resistance CrataBL glioblastoma mesenchymal stem cells microenvironment plant lectin protease inhibitor cryptolepine neocryptolepine isocryptolepine antiproliferative activity structure activity relationships Licochalcone A ATM-Chk2 13-ethylberberine mitochondrial ROS RT-R breast cancer cells diallyl disulfide PI3K/Akt/mTOR pathway Pulsatilla saponin D SB365 glioblastoma multiforme autophagic flux inhibition lysosomal membrane permeabilization mitochondrial membrane potential CLEFMA p38 proanthocyanins TNF-α lung adenocarcinoma natural compounds cervical cancer cell cycle arrest dicentrine metastasis glioma semi-synthetic derivative ingenol Euphorbia tirucalli protein kinase C seaweed porphyran carrageenan anti-cancer natural products |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557419703321 |
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Fabiani Roberto
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antitumoral Properties of Natural Products : Volume 2
| Antitumoral Properties of Natural Products : Volume 2 |
| Autore | Fabiani Roberto |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (300 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
cytotoxic activity
NCI-60 cancer cell line pristimerin Salacia crassifolia Celastraceae Brazilian Cerrado biome Salacia elliptica Cheiloclinium cognatum Plenckia populnea Aspergillus fumigatus Cordyceps sinensis isochromanes chiral resolution ECD calculation cytotoxicity coronarin D JNK osteosarcoma Zeylenone gastric cancer invasion migration apoptosis anti-cancer agents anthraquinones glycosyltransferase Dendrobium officinale structure elucidation anti-tumor activity plantation mode AR Ganoderma tsugae lipogenesis prostate cancer SREBP-1 ursolic acid betulinic acid triterpenoids necrotic quercetin quercetagetin patuletin lichen secondary metabolites tumidulin stemness potential colorectal cancer cells oncogene transcriptional regulation neferine FAK/S6K1 autophagy human neuroblastoma cells natural yellow Monascus pigments water-soluble antioxidation MCF-7 cells phloretin cell proliferation inflammation glucose uptake Catalpa speciosa Taxus cuspidata Magnolia acuminata phenols antioxidants anticancer Colocasia esculenta food bioactive tarin stable nanocapsules entrapment efficiency no-toxicity preclinical tests antitumoral activity chemotherapeutic adjuvant grape leaves ASE TP Antioxidant activities Antiproliferative pro-apoptotic effects Gene expression Nutraceuticals Cucurbitacin B gefitinib-resistant NSCLC EGFR lysosomal degradation CIP2A zerumbone cancer NF-κB IL-6/JAK2/STAT3 Akt FOXO1 multiple myeloma quality control naringenin flavonoids traditional preparation cancer stem cells phytochemicals plant-derived foods fruit vegetable cell signaling Artemisia absinthium endoplasmic reticulum stress mitochondrial-dependent pathway melanoma bee venom melittin temozolomide AKT MAPK antrodin C mTOR metabolic stability capsazepine inflammatory diseases ROS TRPV1 PI3K/AKT/mTOR CLE-10 LC3 MDA-MB-231 lactoferrin hydrolysate copper manganese gastric cancer cells anti-cancer activity molecular mechanism natural product alkaloids cephalotaxine protein synthesis inhibition antiproliferation agents folk medicine DLD-1 cells doxorubicin chemotherapy drug resistance CrataBL glioblastoma mesenchymal stem cells microenvironment plant lectin protease inhibitor cryptolepine neocryptolepine isocryptolepine antiproliferative activity structure activity relationships Licochalcone A ATM-Chk2 13-ethylberberine mitochondrial ROS RT-R breast cancer cells diallyl disulfide PI3K/Akt/mTOR pathway Pulsatilla saponin D SB365 glioblastoma multiforme autophagic flux inhibition lysosomal membrane permeabilization mitochondrial membrane potential CLEFMA p38 proanthocyanins TNF-α lung adenocarcinoma natural compounds cervical cancer cell cycle arrest dicentrine metastasis glioma semi-synthetic derivative ingenol Euphorbia tirucalli protein kinase C seaweed porphyran carrageenan anti-cancer natural products |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Antitumoral Properties of Natural Products |
| Record Nr. | UNINA-9910557531303321 |
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Fabiani Roberto
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biological Activity and Applications of Natural Compounds
| Biological Activity and Applications of Natural Compounds |
| Autore | Seca Ana M. L |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (206 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
amino acid metabolism
carvacrol metabolomics data oxidative stress Penicillium digitatum Prangos pabularia Lindl volatile oil PTP-1B osthole 5-pentylcyclohexa-1,3-diene antidiabetic activity chalcones aldol condensation biological activity flavanones cytotoxic antioxidant anticholinesterase Maytenus celastroloids semisynthesis antibacterial activity structure–activity relationship rosemary rosmarinic acid anticancer antidiabetic cardioprotective Helianthus annuus Helianthus strumosus Aspergillus niger Candida albicans Cryptococcus neoformans α-pinene oleracone flavonoid anti-aging longevity Portulaca oleracea L. Caenorhabditis elegans total synthesis pimenta d’água Candida fungistatic effect inhibition of dimorphism GC/MS colorectal cancer Salviae miltiorrhizae radix apoptosis honey propolis phenolic compounds wound-healing activity NHDF cells Asteraceae sesquiterpene lactones alantolactone arglabin parthenolide thapsigargin in vivo study anti-inflammatory almond byproducts chlorogenic acid design of experiment phenolic acids ultrasound-assisted extraction natural compounds therapeutic applications essential oils antimicrobial antitumor SAR |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557291403321 |
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Seca Ana M. L
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biological and Pharmacological Activity of Plant Natural Compounds
| Biological and Pharmacological Activity of Plant Natural Compounds |
| Autore | Pezzani Raffaele |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (296 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
natural products
phenylpropanoids phenolic acids plants depression behavioral disorders forced swim test tail suspension test anti-cancer activities multifloroside 10-oxyderivatives of oleoside secoiridoids structure-activity relationship flow cytometry epigallocatechin-3-gallate EGCG catechin green tea cancer preventive pharmacological activities Amelanchier alnifolia Nutt carriers powders bioactive compounds functional food Ageratina havanensis flavonoids UPLC-ESI-MS/MS P-glycoprotein antioxidant potential nootkatone anti-inflammatory acute inflammation granuloma Pharbitis nil colorectal cancer KRAS muscle function juglone NLRP3 inflammasome caspase-1 IL-1β IL-18 plant secondary metabolites natural compounds biological activity phytochemistry pharmacological activity plant side effects Talisia esculenta Brosimum gaudichaudii Genipa americana Bromelia antiacantha RA-3 nephrotoxicity triterpene antioxidant hyperuricemia Hibiscus acetosella phenolic compound antibacterial UPLC Tabebuia impetiginosa Taheebo traditional uses immunopharmacology immunological disorders hesperidin new-clean process extraction nanocrystals anti-ageing zingerone lipopolysaccharide inflammation anti-oxidant cytokine storm procalcitonin histopathology doxorubicin Mahonia aquifolium matrix metalloproteinases cytotoxicity human lung adenocarcinoma |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557471303321 |
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Pezzani Raffaele
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biomaterial-Related Infections
| Biomaterial-Related Infections |
| Autore | Rodrigues Célia F |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (204 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Candida
biofilms diabetes medical devices candidiasis metabolic disorder hyperglycemia infection Candida glabrata candidemia echinocandins resistance micafungin caspofungin in vivo titanium dioxide nanotubes autoclaving titanium alloy biocompatibility wettability mechanical properties silver nanoparticles titanium dioxide nanotubes silver ions release biointegration antimicrobial activity polyethylene terephthalate PET electrospinning nanofibers antimicrobial agents Taguchi method antimicrobial efficiency cold atmospheric-pressure plasma jet (CAPJ) Escherichia coli DNA double-strand breaks scanning electron microscopy Ti6Al4V implants anodization process XPS genotoxicity assessment anti-inflammatory properties oral biofilm infection control Streptococcus mutans Candida spp natural compounds antimicrobial resistance |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557289503321 |
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Rodrigues Célia F
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cellular Oxidative Stress
| Cellular Oxidative Stress |
| Autore | Marino Angela |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (529 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
neuroinflammation
clinical palmitoylethanolamide luteolin co-ultramicronization CNS pathology adaptive immune response cell homeostasis legumes liver hepatic steatosis lipid dyshomeostasis ROS traumatic brain injury palmitoylethanolamide (PEA) therapeutic strategies oxidative stress RNA-Seq RPE Retinitis pigmentosa A2E diabetes glucose exposure Band 3 protein erythrocytes SO42− 4-hydroxy-2-nonenal 3-glutathionyl-4-hydroxynonanal astrocytoma cells soy soybeans soy foods antioxidants reactive oxygen species cardiovascular diseases cancer paw edema cashew nuts antioxidant inflammation polyphenols analgesic d-Galactose glycation SO42− uptake anion exchange diseases immune system NF-κB cigarette smoke extract nasal fibroblasts tissue inhibitor of metalloproteinases matrix metalloproteinase steroids Plasmodium falciparum syk kinase inhibitors artemisinin derivatives hemichromes cellular redox state mitochondrial function cisplatin nephrotoxicity acute pancreatitis obesity nitrosative stress PGC-1α microparticles vesiculation band 3 tert-Bytyl hydroperoxide t-BOOH nitric oxide donor calcium ionophore A23187 age-related macular degeneration (AMD) diet Substance-P adipose-derived stem cells paracrine factors epilepsy status epilepticus Trolox HeLa prooxidant AVD apoptosis neurodegeneration ncRNA miRNA tRNA fragments lncRNA circRNA preeclampsia hemostasis platelets coagulation fish mucosal immunity nasal immunity peroxide vitamin C NAC immunosenescence T cells vaccination aging microvascular permeability bradykinin interleukin 1β NADPH oxidase simvastatin molecular hydrogen autophagy matrix metalloproteinases reactive oxygen species (ROS) phytochemicals dietary chemicals natural compounds programmed cell death anoikis ferroptosis pyroptosis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557338703321 |
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Marino Angela
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Computational Approaches: Drug Discovery and Design in Medicinal Chemistry and Bioinformatics
| Computational Approaches: Drug Discovery and Design in Medicinal Chemistry and Bioinformatics |
| Autore | Tutone Marco |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (387 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
3D-QSAR
pharmacophore modeling ligand-based model HDACs isoform-selective histone deacetylase inhibitors aminophenylbenzamide hERG toxicity drug discovery fingerprints machine learning deep learning gene expression signature drug repositioning approaches RNA expression regulation high-throughput virtual screening dual-target lead discovery neurodegenerative disorders Alzheimer's disease dual mode of action multi-modal nicotinic acetylcholine receptor acetylcholinesterase molecular docking methotrexate drug resistance human dihydrofolate reductase virtual screening molecular dynamics simulation epitope binning epitope mapping epitope prediction antibody:antigen interactions protein docking glycoprotein D (gD) herpes simplex virus fusion proteins Src inhibitors pharmacophore model molecular dynamics simulations in silico COX-2 inhibitors molecular modeling sodium-glucose co-transporters 2 FimH uropathogenic bacteria urinary tract infections diabetes drug-resistance mutations HIV-2 protease structural characterization induced structural deformations SARS-CoV-2 COVID-19 multiprotein inhibiting natural compounds MD simulation 3CL-Pro antivirals docking simulations drug repurposing consensus models binding space isomeric space MRP4 SNPs variants protein threading modeling molecular dynamics binding site hTSPO PK11195 cholesterol homology modeling molecular dynamics (MD) simulation carbon nanotubes Stone-Wales defects haeckelite defects doxorubicin encapsulation drug delivery system binding free energies noncovalent interactions main protease mutants inhibitors PF-00835231 Mycobacterium tuberculosis tuberculosis proteasome natural compounds multiscale multitargeting polypharmacology computational biology drug repositioning structural bioinformatics proteomic signature skin aging oxidative stress aging progression mechanism genome-wide genetic and epigenetic network (GWGEN) systems medicine design multiple-molecule drug immunoproteasome non-covalent inhibitors MD binding metadynamics induced-fit docking |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Computational Approaches |
| Record Nr. | UNINA-9910557519403321 |
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Tutone Marco
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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In Silico Strategies for Prospective Drug Repositionings
| In Silico Strategies for Prospective Drug Repositionings |
| Autore | Udrescu Lucreția |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (288 p.) |
| Soggetto topico |
Medicine
Pharmaceutical industries |
| Soggetto non controllato |
COVID-19
drug repurposing topological data analysis persistent Betti function SARS-CoV-2 network-based pharmacology combination therapy nucleoside GS-441524 fluoxetine synergy antidepressant natural compounds QSAR molecular docking drug repositioning UK Biobank vaccine LC-2/ad cell line drug discovery docking MM-GBSA calculation molecular dynamics cytotoxicity assay GWAS multiple sclerosis oxidative stress repurposing ADME-Tox bioinformatics complex network analysis modularity clustering ATC code hidradenitis suppurativa acne inversa transcriptome proteome comorbid disorder biomarker signaling pathway druggable gene drug-repositioning MEK inhibitor MM/GBSA Glide docking MD simulation MM/PBSA single-cell RNA sequencing pulmonary fibrosis biological networks p38α MAPK allosteric inhibitors in silico screening computer-aided drug discovery network analysis psychiatric disorders medications psychiatry mental disorders toxoplasmosis Toxoplasma gondii in vitro screening drug targets drug-disease interaction target-disease interaction DPP4 inhibitors lipid rafts |
| ISBN | 3-0365-6133-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639987703321 |
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Udrescu Lucreția
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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