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Nanobody
| Nanobody |
| Autore | Rothbauer Ulrich |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (300 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Bacillus anthracis
immunoassay single-domain antibody genetic fusion Beta galactosidase P-type ATPase nanobody llama Zinc-transport Zinc-transporting P-ATPase ZntA TNF fluorescent nanobodies sensor anti-cytokine therapy autoimmune disease Western equine encephalitis virus MagPlex toxin antibody camelid vaccine biodefense hydrogen exchange-mass spectrometry virus formatting Fc-domain half-life ischemia stroke MCAO single domain antibodies phage display intrabody intracellular antibody GTPase RHO BRET RAS chromobodies live-cell imaging compound screening cellular models single-domain antibody fragments molecular imaging molecular therapy nuclear imaging targeted fluorescence imaging intraoperative imaging Nanobody Single Domain Antibody Cancer Immunotherapy Imaging influenza influenza B virus hemagglutinin single domain antibody NanobodyTM yeast display epitope mapping GFP C. elegans development drosophila zebrafish targeted photodynamic therapy hepatocyte growth factor receptor HGFR c-Met Met VHH photosensitizer single-domain antibodies neurodegenerative diseases brain imaging blood-brain barrier delivery Aids HIV Llama Antibodies bi-specific VHH pepscan competition studies co-crystallisation |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557147503321 |
Rothbauer Ulrich
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Radiopharmaceuticals for PET Imaging - Issue A
| Radiopharmaceuticals for PET Imaging - Issue A |
| Autore | Roivainen Anne |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (212 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
kinetic analysis
Siglec-9 gallium-68 vascular adhesion protein VAP-1 infection inflammation osteomyelitis animal model Staphylococcus aureus multiple myeloma positron emission tomography/computed tomography radiopharmaceuticals 18F-fluorodeoxyglucose tetrazine ligation PET SPECT indium-11 fluorine-18 positron emission tomography (PET), defluorination isotopic exchange silicon-based fluoride acceptor bioorthogonal chemistry tetrazine inverse electron-demand Diels-Alder ligation opioid naloxone overdose fentanyl carfentanil [11C]carfentanil positron emission tomography receptor occupancy pharmacokinetics [18F]AlF NOTA NODAGA PODS thiol-reactive linker affibody molecule bioconjugation EGFR tumor imaging vulnerable plaque molecular imaging PET imaging nanobody single-domain antibody sub-millimetre resolution AlF-radiolabelling preclinical radiopharmaceutical dosimetry image-based internal dosimetry OLINDA MCT1/MCT4 lactate transporter inhibitor [18F]FACH radiation safety sigma-1 receptor availability orthotopic xenograft of glioblastoma in mouse small animal Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI) (S)-(−)-[18F]fluspidine imaging-based biomarker SV2A protein PET radiotracers synaptic loss radiochemistry preclinical development clinical outcomes monocarboxylate transporters (MCTs) FACH 18F-labeled analog of FACH α-CCA blood-brain barrier (BBB) positron emission tomography (PET) imaging peptides proteolysis metabolic stability |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557437003321 |
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Roivainen Anne
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Advances in Antibody Therapeutics
| Recent Advances in Antibody Therapeutics |
| Autore | Heo Yong-Seok |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (238 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
interleukin 33
ST2 receptor scFv C2_2E12 bladder cancer antibodies immune checkpoint inhibitors antibody-drug conjugates sacituzumab govitecan enfortumab vedotin erdafitinib cost-effectiveness G protein-coupled receptor membrane protein antigen therapeutic antibody anti-angiogenesis delta-like ligand irinotecan paclitaxel VEGF SARS-CoV-2 spike protein receptor-binding domain phage display monoclonal antibody cytomegalovirus peptide/major histocompatibility complex class I complex T-cell-receptor-like antibody affinity maturation yeast surface display combinatorial antibody library agonist antibody cell fate bispecific antibodies bioassays mechanisms of action binding assays potency assays atherosclerosis inflammation antibody therapy blood-brain barrier antibody pharmacokinetics disposition biochemical and physicochemical properties Fc binding receptor-mediated transcytosis brain shuttle molecular Trojan horse transferrin anti-cancer antibody antibody engineering biophysical properties computational methods research cell bank antibody therapeutics recombinant antibodies intracellular antibodies single-chain antibody fragment nanobody Human papillomaviruses HPV oncoproteins HPV-associated cancer HPV cancer therapy asthma refractory asthma biomarker |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580204803321 |
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Heo Yong-Seok
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Conformational Universe of Proteins and Peptides: Tales of Order and Disorder
| The Conformational Universe of Proteins and Peptides: Tales of Order and Disorder |
| Autore | Leone Marilisa |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (230 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
mass spectrometric epitope mapping
gas phase immune complex dissociation apparent gas phase dissociation constants apparent gas phase activation energies ITEM-TWO native mass spectrometry TRIOBP cancer deafness hearing loss mental illness schizophrenia actin cytoskeleton disordered structure protein aggregation solid-state NMR ELDOR-detected NMR ATP hydrolysis ATP analogues DnaB helicase ABC transporter biopesticides antifungal activity insecticidal activity mechanism of action transgenic crops protein folding NMR High Hydrostatic Pressure ACE2 viral spike receptor-binding domain SARS-CoV-2 transmission bioinformatics IDP 1 binding 2 molecular dynamics 3 MELD×MD 4 advanced sampling 5 p53 6 MDM2 7 NAD(P)H-dependent oxidoreductase zinc-containing alcohol dehydrogenase cofactor binding and release interdomain cleft dynamics molecular dynamics simulations denatured state ensemble protein coil library peptides intrinsically disordered proteins ion-pairing interaction side-chain length charged amino acids β-hairpin peptide Friedman's test backbone atom coordinate variances and uncertainties superimposition nanobody protein structure immunoglobulin domain |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Conformational Universe of Proteins and Peptides |
| Record Nr. | UNINA-9910557371103321 |
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Leone Marilisa
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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