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Opioids and Their Receptors : Present and Emerging Concepts in Opioid Drug Discovery
| Opioids and Their Receptors : Present and Emerging Concepts in Opioid Drug Discovery |
| Autore | Spetea Mariana |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (358 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
opioid receptors
neurokinin-1 receptor peptide synthesis receptor binding studies functional assay writhing test tolerance Leu-enkephalin beta-arrestin mu opioid receptor delta opioid receptor biased signaling DADLE ischemia plasma stability morphinan BNTX δ opioid receptor antagonist 1H-NMR experiments mechanism elucidation peripheral antinociception 14-methoxycodeine-6-O-sulfate codeine-6-O-sulfate opioid peptides and peptidomimetics DAMGO DALDA [Dmt1]DALDA KGOP01 binding molecular docking structure-activity relationships β2-amino acids β2-Homo-amino acids µ-opioid receptor opioid peptides TAPP racemic synthesis of β2-amino acids peripheral µ-opioid receptors analgesia peripheral analgesic tolerance dysbiosis opioid bifunctional ligands (−)-N-phenethylnorhydromorphone analogs [35S]GTPgammaS assay forskolin-induced cAMP accumulation assays β-arrestin recruitment assays MOR and DOR agonists respiratory depression bias factor molecular modeling & simulation δ opioid receptor NTI derivative sulfonamide inverse agonist neutral antagonist agonist opioids mu receptor opioid side effects biased agonism partial agonism zerumbone chronic constriction injury (CCI) allodynia hyperalgesia potassium channels over-the-counter drugs misuse abuse opioid drugs pharmacology codeine dihydrocodeine loperamide opioid peptide macrocyclic tetrapeptide multifunctional ligands kappa opioid receptor analgesics opioid liabilities μ opioid receptor receptor model biased ligands dependence pain therapy neonatal opioid withdrawal syndrome naltrexone 6β-naltrexol buprenorphine G-protein bias arrestin recruitment respiration mitragynine heteromer internalization primary hippocampal culture lysosomes µ opioid receptor molecular dynamics docking interaction fingerprints biased agonists SR-17018 PZM21 morphine fentanyl diphenethylamines design and synthesis partial agonist biased agonist antagonist binding affinity selectivity |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Opioids and Their Receptors |
| Record Nr. | UNINA-9910557108003321 |
Spetea Mariana
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pharmacist Services
| Pharmacist Services |
| Autore | Olson Anthony |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (436 p.) |
| Soggetto non controllato |
medication experience
medication safety collaborative practice age disparities Comprehensive Medication Management pharmacist pharmaceutical care readmissions healthy people 2020 multiple chronic conditions comparative case study billing interprofessional care clinical pharmacy safety community pharmacy qualitative research 21st century history medication management innovation science clinical results healthcare access documentation cost avoidance code of ethics misuse intention experiential learning opioid use disorder pharmacist workforce adverse drug events cue orientation pharmacy intern continuity of patient care decision-making community-based pharmacist practitioners service process quality assurance vaccination medication-related problems medication therapy management chronic kidney disease services marketing pharmacist roles health workers disposal federally qualified health center pharmacy services student pharmacist pharmacy communication interrupted time series analysis interprofessional practice and education 20th century history pharmacist services transitions in care retail clinics pharmacy clinical services counseling brown bag chronic diseases observation medication therapy problems ambulatory care mobile health units human papilloma virus community-based pharmacy medication reconciliation pharmacy learners collaboration care plan primary care interprofessional training travel theory of planned behavior information sharing pharmacy practice health care policy medication adherence ethics pharmaceutical intervention medication synchronization counselling comprehensive medication review medication use burden dispensing pharmacy staff communication mental illness pharmacy benefit manager (PBM) focus group interviews South Asian pharmaceutical regulation wellness programs serviced marketing emergency unit immunization pharmacy quality measurement/benchmarking advanced practice pharmacist provider job satisfaction job-related preferences naltrexone medication discrepancies interprofessional CMS Star rating HPV vaccination regulatory clinical practice community pharmacists ethical models immunization programs health policy nurse practitioners history of pharmacy cystic fibrosis focus groups community pharmacy practice gender disparities pharmaceutical care practice comprehensive medication management value design thinking grants value-added services pharmacists adherence implementation opioid primary health care mental health first aid pharmacy practice faculty community pharmacy services comprehensive medication management services pharmacy education coordinated care management mental health care competitive advantage organizations Denmark naloxone compensation |
| ISBN | 3-03921-755-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367748103321 |
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Olson Anthony
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||