Muscle Homeostasis and Regeneration : From Molecular Mechanisms to Therapeutic Opportunities

• Autore: Musarò Antonio
• Pubblicazione: Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020
• Descrizione fisica: 1 online resource (500 p.)
• Soggetto topico: Biology, life sciences; Research and information: general
• Soggetto non controllato: acetylcholine receptor; Acvr1b; aging; atrophy; biomarkers; C2C12 cells; calcium homeostasis; cell culture; cell precursors; Col1a1; confocal microscopy; connexin 26; connexin 43; CRISPR-Cas9; denervation; differentiation; Drosophila; Duchenne muscular dystrophy; electron microscopy; evolution; exercise; exon deletion; exosomes; experimental methods; extracellular vesicles; FAPs; fascicle; fibro/adipogenic progenitors; fibrosis; gap junctions; genetic control; genetic variation; genotype; growth factors; heavy resistance exercise; heterotopic ossification; hibernation; Hibernation; HO precursors; hyperplasia; hypertrophy; IGF2R; immunocytochemistry; inflammation; inflammatory response; iPSC; longitudinal growth; lysine; macrophages; mass cytometry; metazoans; mitochondria; mitochondrial dynamics; mitochondrial fission; mitochondrial fusion; mitochondrial quality control; mitochondrial-derived vesicles (MDVs); mitochondrial-lysosomal axis; mitophagy; mTORC1; muscle; muscle atrophy; muscle differentiation; muscle diversification; muscle homeostasis; muscle pathology; muscle phenotypes; muscle populations; muscle precursors; muscle regeneration; muscle satellite cell; muscle stem cells; muscles; muscular dystrophy; myofiber; myofibril; myofibroblasts; myogenesis; myogenic progenitors; myostatin; neonatal myosin; neural cell adhesion molecule; neuromuscular disorders; neuromuscular junction; NF-Y; Nfix; pericytes; phagocytosis; pharmacological approach; Platelet-Rich Plasma; proliferation; radial growth; regenerative medicine; RhoA-ROCK1; sarcomere; sarcopenia; sarcoplasmic reticulum; satellite cells; septicemia; single-cell; skeletal muscle; skeletal muscle growth; skeletal muscle homeostasis; skeletal muscle regeneration; skeletal muscle stem and progenitor cells; splicing isoforms; splitting; stem cell markers; stem cells; stem cells niche; Tgfbr1; thyroid hormone; tissue niche; transdifferentiation; transforming growth factor (TGF)-β1; transthyretin; α-smooth muscle actin
• Persona (resp. second.): MusaròAntonio
• Sommario/riassunto: The book is a collection of original research and review articles addressing the intriguing field of the cellular and molecular players involved in muscle homeostasis and regeneration. One of the most ambitious aspirations of modern medical science is the possibility of regenerating any damaged part of the body, including skeletal muscle. This desire has prompted clinicians and researchers to search for innovative technologies aimed at replacing organs and tissues that are compromised. In this context, the papers, collected in this book, addressing a specific aspects of muscle homeostasis and regeneration under physiopathologic conditions, will help us to better understand the underlying mechanisms of muscle healing and will help to design more appropriate therapeutic approaches to improve muscle regeneration and to counteract muscle diseases.
• Altri titoli varianti: Muscle Homeostasis and Regeneration
• Titolo autorizzato: Muscle Homeostasis and Regeneration
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910557587003321
• Lo trovi qui: Univ. Federico II