Autore	Ohradanova-Repic Anna
Pubbl/distr/stampa	Frontiers Media SA, 2020
Descrizione fisica	1 online resource (224 p.)
Soggetto topico	Immunology Medicine and Nursing
Soggetto non controllato	cell fate decisions immune cell regulation immunometabolism innate lymphoid cells metabolic reprogramming myeloid cells T cells
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Record Nr.	UNINA-9910557426303321

Pubbl/distr/stampa	Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020
Descrizione fisica	1 online resource (578 p.)
Soggetto topico	Biology, life sciences Research & information: general
Soggetto non controllato	ADAM17 adoptive T cell therapy AKT androgens apoptosis autoimmune disease autosomal-dominant hyper IgE syndrome Bone Marrow Failure Syndromes breast cancer cancer cancer models cancer progression cancer-stem cell CD38 CD4+ T cells CD8+ T cells cell cycle cell hierarchy chaperones chemotherapy resistance cirrhosis colon cancer companion animals comparative oncology cytokine cytokine receptor signaling dynamic programming endoplasmic reticulum (ER) stress epidermal growth factor receptor (EGF-R) ERK1/2 escape mechanisms gain-of-function mutation glioblastoma glioma growth hormone insensitivity syndrome heat shock proteins hedging hematopoietic cancers hepatitis C virus (HCV) hepatocellular carcinoma (HCC) hepatocyte nuclear factor 4 alpha (HNF4A) immune check point immune suppression immunosuppression immunotherapy inflammation inflammation associated cancer inflammatory hepatocellular adenomas interleukin-6 JAK JAK family of protein tyrosine kinases JAK2 V617F knockout lipopolyplex lung cancer lymphocytes lymphoma M2 macrophages melanoma meta-analysis metalloprotease metastasis microRNA-122 (miR-122) mitochondria MPN mTOR multiple myeloma mutations myeloid cells myeloid leukemia n/a nanoparticle neoplastic stem cells NGS NK cells nuclear factor erythroid 2-related factor 2 (NRF2) nuclear pore complex nuclear transport receptors nucleocytoplasmic shuttling ovarian cancer oxidative stress (OS) PD-L1 PEI pharmacological inhibitor pharmacological inhibitors polyethylenimine post-decision state variable prolactin proliferation prostate cancer RHOA risk management S3I-1757 SH2 domain shedding signal transducer and activator of transcription signal transducer and activator of transcription 3 (STAT3) siRNA delivery siRNA/RNAi small-molecule inhibitors solid cancers stabilization STAT STAT transcription factors STAT3 STAT3 inhibitor XIII STAT5 STAT5 signaling STAT5B signaling stem/progenitor cells stemness T-cell large granular lymphocytic leukemia T-cell leukemia T-cell prolymphocytic leukemia T-cells T-PLL targeted therapy targeting therapeutic targeting therapy resistance trans-signaling transaction costs tumor microenvironment tumor necrosis factor alpha (TNFα) tumor suppression tumor-associated macrophages tumor-immune cell interactions tumorigenesis tyrosine kinase 2 unfolded protein response (UPR)
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Record Nr.	UNINA-9910557623503321

Autore	Madureira Patrícia Alexandra Saraiva
Pubbl/distr/stampa	Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021
Descrizione fisica	1 online resource (307 p.)
Soggetto topico	Medicine and Nursing
Soggetto non controllato	3D co-culture biomarker biomarkers bladder cancer breast cancer cancer cancer acidity cancer cells subpopulations cancer development cancer recurrence cancer stem cells cancer-associated fibroblast (CAF) carcinoma chemotherapy response clinical trials colon cancer cross-presentation CTLA-4 cytokine/chemokine darwinian evolution diclofenac evolutionary therapy extracellular matrix (ECM) feline mammary carcinoma glioblastoma (GB) glioma stem cells (GSC) growth factors head and neck cancer histone modification hyperosmolarity hypoxia Hypoxia Inducible Factor (HIF) immune cell infiltration immunomodulatory roles immunotherapy inhibitor KDM5B koningic acid lung cancer macrophages mammary gland metastasis microenvironment molecular docking molecular subtypes of pancreatic cancer myeloid cells myeloid derived suppressor cells myeloid-derived suppressor cells oxidative stress PAI-1 PAI-2 pancreatic stellate cells PD-1 PD-L1 plasmin plasminogen pre-metastatic niche preclinical modelling pro- and anti-tumor immune cells pro-inflammatory cytokines prognosis prostate cancer radioresistance radiosensitivity radiotherapy radiotherapy dose fractionation reactive oxygen species regulatory T cells repurposing resistance S100A10 S100A10 (p11) signaling pathways spheroid stroma syngeneic model targeted therapy therapeutic resistance TNF-α triple negative tumor growth tumor microenvironment tumor progression tumor-associated macrophages tumour microenvironment uPA uPAR
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Record Nr.	UNINA-9910557354203321