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AMP-Activated Protein Kinase Signalling
| AMP-Activated Protein Kinase Signalling |
| Autore | Neumann Dietbert |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (452 p.) |
| Soggetto non controllato |
HDACs
transcription epigenetics spermatozoa par complex A769662 MDCK skeletal muscle AID phosphorylation energy metabolism monocytes autophagy CML liver hindlimb suspension pregnancy preeclampsia gestational diabetes mellitus CaMKK2 assisted reproduction techniques nutrient-sensing signals sonic hedgehog protein acetylation glycogen storage disease AMPK adenosine monophosphate-activated protein kinase AICAR indirect calorimetry IL-1? MyHC I(?) HDAC4/5 endothelial cells infection hepatocyte p70S6K lipid metabolism host defense exercise kidney disease heat shock protein ?RIM mycobacteria activation loop developmental origins of health and disease (DOHaD) CREB TAK1 metabolic-inflammation phenylephrine AMP-activated protein kinase (AMPK) KATs 2-methoxyestradiol DNA methylation NLRP3 pump ?-linker steatosis AMPK kinase stress endothelial nitric-oxide synthase vasodilation adherent junctions epithelial cells glycogen Akt synaptic activation cellular energy sensing glucose uptake transporter co-expression atrophy nutrigenomics motility vasoconstriction fatty acid oxidation oxidative stress AS160 membrane histone modification sirtuin 1 (SIRT1) chromatin remodeling insulin signalling dietary fatty acids ULK CMML adaptive thermogenesis mTOR MDS mechanical unloading AML endothelial function medulloblastoma PKA adipose tissue NAD+ membranes nutrition ZO-1 TBC1D4 adipocyte soluble Adenylyl cyclase metabolism renin-angiotensin system energy utilization proteasome differentiation signaling peroxisome proliferator-activated receptor gamma coactivator 1-? (PGC1?) hypertrophy AMP-activated protein kinase metabolic disease LKB1 soleus muscle macrophages Immediate early genes CBS benign motor endplate remodeling ionomycin nectin-afadin tight junctions resveratrol protein kinase B regrowth mitochondria protein synthesis energy deficiency catechol-O-methyltransferase fiber-type microarrays carrier acetyl-CoA hypertension 3T3-L1 hypothalamus food intake |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346858503321 |
Neumann Dietbert
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Challenges and Advances in Tuberculosis and Mycobacterial Lung Diseases
| Challenges and Advances in Tuberculosis and Mycobacterial Lung Diseases |
| Autore | Szturmowicz Monika |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (140 p.) |
| Soggetto topico | Public health & preventive medicine |
| Soggetto non controllato |
Gordonia bronchialis
microbiological diagnostics respiratory infection Mycobacterium tuberculosis drug resistance XDR-tuberculosis household TB transmission tuberculous pericarditis extrapulmonary tuberculosis pericarditis constrictive pericarditis tuberculosis abscess scrofula head and neck epiglottis larynx airway mycobacteria surgical drainage FluoroType MTBDR molecular isoniazid rifampin bacillus Calmette-Guerin bladder cancer immunotherapy BCGosis BCG pulmonary infection severe respiratory insufficiency nontuberculous mycobacterium lung cancer surgery nontuberculous mycobacteria cystic fibrosis chest computed tomography Beijing-TB Beijing-like genotype Mycobacterium chimaera nontuberculous mycobacterial disease silicosis extracorporeal membrane oxygenation COVID-19 pandemic spoligotyping Poland human immunodeficiency virus acquired immunodeficiency syndrome chest imaging rapidly growing mycobacteria antimicrobial resistance broth microdilution minimal inhibitory concentration (MIC) |
| ISBN | 3-0365-5492-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910637783103321 |
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Szturmowicz Monika
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Feature Paper in Antibiotics for 2019
| Feature Paper in Antibiotics for 2019 |
| Autore | Lipman Jeffrey |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (282 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Antimicrobial resistance
antibiotics antimicrobial stewardship inappropriate prescribing days of therapy Start Smart then Focus piperine piperlongumine antibacterial antifungal synergy non-target feed florfenicol thiamfenicol chloramfenicol HPLC-MS/MS validation swine out-of-hours care primary care quality of care quality indicators practitioners cooperative antibiotic stewardship fluoroquinolones guidelines urinary tract infections quality improvement general practitioners guideline health inequalities health equity assessment tool public health Enterobacteriaceae carbapenem-resistant CRE antibiotic resistance antimicrobials bacteriophages biofilms novel antimicrobials Antibiotics resistance broad-spectrum agents hospital epidemiology antibiotic utilization infection control infection prevention Pseudomonas aeruginosa Acinetobacter baumannii extended-spectrum beta-lactamases carbapenem-resistant Enterobacteriaceae methicillin-resistant Staphylococcus aureus clinical trials infectious disease phage therapy silver complexes camphorimine anti-Candida activity antifungals antibacterials efflux inhibitors efflux pumps erm(41) mutations mycobacteria verapamil actinomycetes bioactivity polyketides polyketide synthases biosynthesis antimicrobial resistance economic evaluation cost-utility analysis cost-effectiveness analysis policy analysis One Health Singapore antibiotic prescribing implementation behavior change stakeholder consultation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557689603321 |
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Lipman Jeffrey
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Manipulation of the cellular microbicidal response and endocytic dynamic by pathogens membrane factors
| Manipulation of the cellular microbicidal response and endocytic dynamic by pathogens membrane factors |
| Autore | Benjamin Coiffard |
| Pubbl/distr/stampa | Frontiers Media SA, 2015 |
| Descrizione fisica | 1 electronic resource (81 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
rab
RNAi Ubiquitination host-pathogens interaction Coxiella Brucella Planarians Body Lices mycobacteria granulomas Leshmania |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910137093103321 |
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Benjamin Coiffard
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| Frontiers Media SA, 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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PPARs as Key Mediators of Metabolic and Inflammatory Regulation
| PPARs as Key Mediators of Metabolic and Inflammatory Regulation |
| Autore | Vázquez-Carrera Manuel |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (456 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Biochemistry |
| Soggetto non controllato |
nuclear receptor
gene transcription inflammation molecular docking PPARβ/δ lung pulmonary artery GW0742 GSK3787 docking lipopolysaccharide (LPS) PPARγ ligand coumarin fluorescent ligand screening crystal structure PPAR atopic dermatitis psoriasis metabolic reprograming glucose fatty acids mycobacteria M. tuberculosis M. leprae PPARs lipid droplets metabolic alterations hepatic damage nuclear factors pharmacological targets AMPK GDF15 insulin resistance type 2 diabetes mellitus peroxisome proliferator-activated receptor gamma (PPARγ) real-time PCR ELISA immunohistochemistry signaling pathway PPAR gamma brain neural stem cells infection neuroinflammation HIV Zika cytomegalovirus neurogenesis microglia liver damage toll-like receptor 4 P2Y2 receptor metabolic syndrome resveratrol quercetin PPARα peroxisome β-oxidation PPRE ligand coregulator micronutrients PPARα knockout adipose tissue browning lipid metabolism depression PPARg neuropathology corticotropin releasing hormone norepinephrine subgenual prefrontal cortex amygdala nucleus accumbens common carotid artery occlusion electroretinography fibroblast growth factor 21 pemafibrate peroxisome proliferator-activated receptor alpha retinal ischemia skeletal muscle substrate metabolism nonalcoholic fatty liver disease (NAFLD) sex dimorphism lipidomics hepatic sex-biased gene expression PPARγ pulmonary arterial hypertension TGFβ vascular injury proliferation kidney fibrosis pattern-recognition receptors phagocytosis nitric oxide synthase fenofibrate oleoylethanolamide palmitoylethanolamide cancer immunity obesity diabetes miRNA DNA methylation histone modification peroxisome-proliferator-activated receptor fatty acid oxidation doping control regulatory T cells exercise nuclear receptors nutrigenomics energy homeostasis dairy animals non-alcoholic fatty liver disease (NAFLD) non-alcoholic steatohepatitis (NASH) peroxisome proliferator-activated receptors (PPAR) bezafibrate fenofibric acid peroxisome proliferator-activated receptor dual/pan agonist X-ray crystallography |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576873703321 |
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Vázquez-Carrera Manuel
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tuberculosis Drug Discovery and Development 2019
| Tuberculosis Drug Discovery and Development 2019 |
| Autore | Riccardi Giovanna |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (296 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
mycobacteria
tuberculosis multi-drug resistance drug discovery promiscuous targets Mycobacterium tuberculosis rifampin isoniazid mechanisms of resistance mutations granulomas caseum cell envelope dormancy delpazolid macozinone DprE1 inhibitor clinical studies discovery mode of action drug resistance toxicity target energy metabolism electron transport chain oxidative phosphorylation bedaquiline Q203 MID3 pharmacokinetics pharmacodynamics drug-drug interactions in vitro in vivo drug development tuberculosis treatment biomarkers drug combination clinical trial BCG tuberculosis vaccines TBVI EDCTP IAVI CTVD host-directed therapy anti-virulence compounds TB post-treatment sequelae surgery pulmonary rehabilitation Carlo Forlanini artificial pneumothorax structure-based drug design target-based drug design PknB PknG DNA gyrase antibiotic mycobacterium genomics transcriptomics proteomics metabolomics lipidomics target identification mechanism of action antimicrobial drug resistance (AMR) target-based screening phenotypic screening antituberculosis agents antimycobacterial anti-TB drug pipeline privileged targets lead generation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557627203321 |
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Riccardi Giovanna
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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